Gergely Rona
Department of Biochemistry and Molecular Pharmacology,
Laura and Isaac Perlmutter Cancer Center,
Howard Hughes Medical Institute
New York University School of Medicine
Currently I work as a Postdoctoral Fellow at the NYU Grossman School of Medicine and at HHMI in the field of DNA Damage and Repair. As a molecular biologist, I am trying to gain a better understanding about the fundamental processes that maintain genomic integrity within our cells. I find it intriguing how information encoded in our genome is maintained with an unparalleled precision yet at the same time is plastic enough to be able to adopt to environmental changes. DNA repair is also crucial in cancer biology as mis-regulation of this process is often a driving force of several cancer types and diseases.
Cyclin F-Mediated Degradation of SLBP Limits H2A.X Accumulation and Apoptosis upon Genotoxic Stress in G2.
Molecular cell Nov, 2016 | Pubmed ID: 27773672
Identification of Extracellular Segments by Mass Spectrometry Improves Topology Prediction of Transmembrane Proteins.
Scientific reports 02, 2017 | Pubmed ID: 28211907
PARP1-dependent recruitment of the FBXL10-RNF68-RNF2 ubiquitin ligase to sites of DNA damage controls H2A.Z loading.
eLife 07, 2018 | Pubmed ID: 29985131
CRISPR/Cas9-Mediated Knock-Out of dUTPase in Mice Leads to Early Embryonic Lethality.
Biomolecules 04, 2019 | Pubmed ID: 30987342
Absence of the Tks4 Scaffold Protein Induces Epithelial-Mesenchymal Transition-Like Changes in Human Colon Cancer Cells.
Cells 10, 2019 | Pubmed ID: 31671862
Mixed ubiquitin chains regulate DNA repair.
Genes & development 12, 2019 | Pubmed ID: 31792015
Interaction between NSMCE4A and GPS1 links the SMC5/6 complex to the COP9 signalosome.
BMC molecular and cell biology May, 2020 | Pubmed ID: 32384871
Genome-wide alterations of uracil distribution patterns in human DNA upon chemotherapeutic treatments.
eLife 09, 2020 | Pubmed ID: 32956035
AMBRA1 regulates cyclin D to guard S-phase entry and genomic integrity.
Nature Apr, 2021 | Pubmed ID: 33854232
CRL4 is a master regulator of D-type cyclins.
Nature Apr, 2021 | Pubmed ID: 33854235
The NSP14/NSP10 RNA repair complex as a Pan-coronavirus therapeutic target.
Cell death and differentiation Feb, 2022 | Pubmed ID: 34862481
Extrachromosomal DNA Amplification Contributes to Small Cell Lung Cancer Heterogeneity and Is Associated with Worse Outcomes.
Cancer discovery Apr, 2023 | Pubmed ID: 36715552
Visualizing Single-Stranded DNA Foci in the G1 Phase of the Cell Cycle
1Department of Biochemistry and Molecular Pharmacology, NYU Grossman School of Medicine,
2The Laura and Isaac Perlmutter Cancer Center, NYU Langone Health,
3Department of Cell Biology, NYU Grossman School of Medicine,
4Howard Hughes Medical Institute, NYU Grossman School of Medicine,
5Institute of Enzymology, Centre of Excellence of the Hungarian Academy of Sciences, HUN-REN Research Centre for Natural Sciences
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