Leonard Zon

Children's Hospital, Harvard Medical School

Affiliated withHarvard Medical School Children’s Hospital Boston

Research Area

Biology

Biography

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title	2007
Publication title	2009

Other Publications

Article	Year
Organogenesis--heart and blood formation from the zebrafish point of view. Science (New York, N.Y.)\| PubMed ID: 11799232	2002
Non-cell autonomous requirement for the bloodless gene in primitive hematopoiesis of zebrafish. Development (Cambridge, England)\| PubMed ID: 11830566	2002
Hematopoiesis and stem cells: plasticity versus developmental heterogeneity. Nature immunology\| PubMed ID: 11919568	2002
Walking the walk: migration and other common themes in blood and vascular development. Cell\| PubMed ID: 11955426	2002
Evolutionary conservation of zebrafish linkage group 14 with frequently deleted regions of human chromosome 5 in myeloid malignancies. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 11983906	2002
Zebrafish SPI-1 (PU.1) marks a site of myeloid development independent of primitive erythropoiesis: implications for axial patterning. Developmental biology\| PubMed ID: 12051816	2002
Zebrafish as a cancer model system. Cancer cell\| PubMed ID: 12086858	2002
Neuropilin-1 is required for vascular development and is a mediator of VEGF-dependent angiogenesis in zebrafish. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12142468	2002
Attack of the fish clones. Nature biotechnology\| PubMed ID: 12148002	2002
Characterization of zebrafish merlot/chablis as non-mammalian vertebrate models for severe congenital anemia due to protein 4.1 deficiency. Development (Cambridge, England)\| PubMed ID: 12183387	2002
Isolation and characterization of zebrafish NFE2. Physiological genomics\| PubMed ID: 12388799	2002
The zebrafish mutant gene chardonnay (cdy) encodes divalent metal transporter 1 (DMT1). Blood\| PubMed ID: 12393445	2002
SUMO-1 modification represses Sp3 transcriptional activation and modulates its subnuclear localization. Molecular cell\| PubMed ID: 12419227	2002
SUMO-1 protease-1 regulates gene transcription through PML. Molecular cell\| PubMed ID: 12419228	2002
Portrait of a stem cell. Developmental cell\| PubMed ID: 12431368	2002
Isolation and characterization of runxa and runxb, zebrafish members of the runt family of transcriptional regulators. Experimental hematology\| PubMed ID: 12482499	2002
Ontogeny of hematopoiesis: examining the emergence of hematopoietic cells in the vertebrate embryo. Current topics in developmental biology\| PubMed ID: 12510667	2003
Biomedicine. Love, honor, and protect (your liver). Science (New York, N.Y.)\| PubMed ID: 12574609	2003
Myc-induced T cell leukemia in transgenic zebrafish. Science (New York, N.Y.)\| PubMed ID: 12574629	2003
Characterization of embryonic globin genes of the zebrafish. Developmental biology\| PubMed ID: 12618133	2003
Cell-specific mitotic defect and dyserythropoiesis associated with erythroid band 3 deficiency. Nature genetics\| PubMed ID: 12669066	2003
Cancer genetics and drug discovery in the zebrafish. Nature reviews. Cancer\| PubMed ID: 12835673	2003
The zebrafish spi1 promoter drives myeloid-specific expression in stable transgenic fish. Blood\| PubMed ID: 12869502	2003
Inhibition of zebrafish epidermal growth factor receptor activity results in cardiovascular defects. Mechanisms of development\| PubMed ID: 12915231	2003
The zebrafish van gogh mutation disrupts tbx1, which is involved in the DiGeorge deletion syndrome in humans. Development (Cambridge, England)\| PubMed ID: 12952905	2003
cdx4 mutants fail to specify blood progenitors and can be rescued by multiple hox genes. Nature\| PubMed ID: 13679919	2003
Modeling human hematopoietic and cardiovascular diseases in zebrafish. Developmental dynamics : an official publication of the American Association of Anatomists\| PubMed ID: 14579393	2003
Transplantation and in vivo imaging of multilineage engraftment in zebrafish bloodless mutants. Nature immunology\| PubMed ID: 14608381	2003
Allan j. Erslev, m.d.: truly a great dane (1919-2003). Stem cells (Dayton, Ohio)\| PubMed ID: 14688399	2004
The zebrafish as a model organism to study development of the immune system. Advances in immunology\| PubMed ID: 14711058	2003
The pu.1 promoter drives myeloid gene expression in zebrafish. Blood\| PubMed ID: 14996705	2004
The use of zebrafish to understand immunity. Immunity\| PubMed ID: 15084267	2004
In vivo tracking of T cell development, ablation, and engraftment in transgenic zebrafish. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 15123839	2004
Effects of lethal irradiation in zebrafish and rescue by hematopoietic cell transplantation. Blood\| PubMed ID: 15142873	2004
Expression and mapping of duplicate neuropilin-1 and neuropilin-2 genes in developing zebrafish. Gene expression patterns : GEP\| PubMed ID: 15183302	2004
Taking the stem cell debate to the public. PLoS biology\| PubMed ID: 15208732	2004
Two distinct teleost hepatocyte nuclear factor 1 genes, hnf1alpha/tcf1 and hnf1beta/tcf2, abundantly expressed in liver, pancreas, gut and kidney of zebrafish. Gene\| PubMed ID: 15302404	2004
The zebrafish moonshine gene encodes transcriptional intermediary factor 1gamma, an essential regulator of hematopoiesis. PLoS biology\| PubMed ID: 15314655	2004
The 'definitive' (and 'primitive') guide to zebrafish hematopoiesis. Oncogene\| PubMed ID: 15378083	2004
Analysis of hematopoietic development in the zebrafish. Methods in molecular medicine\| PubMed ID: 15492396	2005
Hematopoietic gene expression profile in zebrafish kidney marrow. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 15520368	2004
The clinical potential of stem cells. Current opinion in cell biology\| PubMed ID: 15530786	2004
An Mll-dependent Hox program drives hematopoietic progenitor expansion. Current biology : CB\| PubMed ID: 15556871	2004
The chianti zebrafish mutant provides a model for erythroid-specific disruption of transferrin receptor 1. Development (Cambridge, England)\| PubMed ID: 15563524	2004
Use of the DsRed fluorescent reporter in zebrafish. Methods in cell biology\| PubMed ID: 15602868	2004
The Zon laboratory guide to positional cloning in zebrafish. Methods in cell biology\| PubMed ID: 15602919	2004
Zebrafish scl functions independently in hematopoietic and endothelial development. Developmental biology\| PubMed ID: 15617691	2005
Loss of gata1 but not gata2 converts erythropoiesis to myelopoiesis in zebrafish embryos. Developmental cell\| PubMed ID: 15621534	2005
tp53 mutant zebrafish develop malignant peripheral nerve sheath tumors. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 15630097	2005
In vivo drug discovery in the zebrafish. Nature reviews. Drug discovery\| PubMed ID: 15688071	2005
BRAF mutations are sufficient to promote nevi formation and cooperate with p53 in the genesis of melanoma. Current biology : CB\| PubMed ID: 15694309	2005
Mutation in the transcriptional coactivator EYA4 causes dilated cardiomyopathy and sensorineural hearing loss. Nature genetics\| PubMed ID: 15735644	2005
The zebrafish: a new model of T-cell and thymic development. Nature reviews. Immunology\| PubMed ID: 15803150	2005
Mutant-specific gene programs in the zebrafish. Blood\| PubMed ID: 15827125	2005
The complex cartography of stem cell commitment. Cell\| PubMed ID: 15851023	2005
Regulation of the lmo2 promoter during hematopoietic and vascular development in zebrafish. Developmental biology\| PubMed ID: 15893977	2005
Ferroportin1 is required for normal iron cycling in zebrafish. The Journal of clinical investigation\| PubMed ID: 15902304	2005
Zebrafish slc4a2/ae2 anion exchanger: cDNA cloning, mapping, functional characterization, and localization. American journal of physiology. Renal physiology\| PubMed ID: 15914778	2005
The iron exporter ferroportin/Slc40a1 is essential for iron homeostasis. Cell metabolism\| PubMed ID: 16054062	2005
Analysis of thrombocyte development in CD41-GFP transgenic zebrafish. Blood\| PubMed ID: 16099879	2005
Deficiency of glutaredoxin 5 reveals Fe-S clusters are required for vertebrate haem synthesis. Nature\| PubMed ID: 16110529	2005
Transcriptional regulation of hematopoietic stem cell development in zebrafish. Experimental hematology\| PubMed ID: 16140148	2005
A zebrafish bmyb mutation causes genome instability and increased cancer susceptibility. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 16150706	2005
Hematopoietic stem cell fate is established by the Notch-Runx pathway. Genes & development\| PubMed ID: 16166372	2005
Zebrafish KLF4 is essential for anterior mesendoderm/pre-polster differentiation and hatching. Developmental dynamics : an official publication of the American Association of Anatomists\| PubMed ID: 16222715	2005
Zebrafish to humans: evolution of the alpha3-chain of type IV collagen and emergence of the autoimmune epitopes associated with Goodpasture syndrome. Blood\| PubMed ID: 16254142	2006
Use of the zebrafish system to study primitive and definitive hematopoiesis. Annual review of genetics\| PubMed ID: 16285869	2005
A critical role for calponin 2 in vascular development. The Journal of biological chemistry\| PubMed ID: 16317011	2006
Genetic analysis of cavefish reveals molecular convergence in the evolution of albinism. Nature genetics\| PubMed ID: 16341223	2006
Piloting the zebrafish genome browser. Developmental dynamics : an official publication of the American Association of Anatomists\| PubMed ID: 16372332	2006
Small molecules that delay S phase suppress a zebrafish bmyb mutant. Nature chemical biology\| PubMed ID: 16372403	2005
The caudal-related homeobox genes cdx1a and cdx4 act redundantly to regulate hox gene expression and the formation of putative hematopoietic stem cells during zebrafish embryogenesis. Developmental biology\| PubMed ID: 16457800	2006
Mitoferrin is essential for erythroid iron assimilation. Nature\| PubMed ID: 16511496	2006
BMP signaling restricts hemato-vascular development from lateral mesoderm during somitogenesis. Development (Cambridge, England)\| PubMed ID: 16672337	2006
AlphaA-crystallin expression prevents gamma-crystallin insolubility and cataract formation in the zebrafish cloche mutant lens. Development (Cambridge, England)\| PubMed ID: 16728471	2006
A novel endothelial-specific heat shock protein HspA12B is required in both zebrafish development and endothelial functions in vitro. Journal of cell science\| PubMed ID: 16968741	2006
Cdx4 dysregulates Hox gene expression and generates acute myeloid leukemia alone and in cooperation with Meis1a in a murine model. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17068127	2006
A chemical genetic screen for cell cycle inhibitors in zebrafish embryos. Chemical biology & drug design\| PubMed ID: 17105485	2006
Homing sweet homing: odyssey of hematopoietic stem cells. Immunity\| PubMed ID: 17174927	2006
A mutation in separase causes genome instability and increased susceptibility to epithelial cancer. Genes & development\| PubMed ID: 17210788	2007
Gene Duplication of the zebrafish kit ligand and partitioning of melanocyte development functions to kit ligand a. PLoS genetics\| PubMed ID: 17257055	2007
Notch and MAML signaling drives Scl-dependent interneuron diversity in the spinal cord. Neuron\| PubMed ID: 17359917	2007
Zebrafish orthologs of human muscular dystrophy genes. BMC genomics\| PubMed ID: 17374169	2007
Network of coregulated spliceosome components revealed by zebrafish mutant in recycling factor p110. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17416673	2007
Effects of RAS on the genesis of embryonal rhabdomyosarcoma. Genes & development\| PubMed ID: 17510286	2007
Heat shock-inducible Cre/Lox approaches to induce diverse types of tumors and hyperplasia in transgenic zebrafish. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17517602	2007
New waves of discovery: modeling cancer in zebrafish. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 17557959	2007
Ultrasound biomicroscopy permits in vivo characterization of zebrafish liver tumors. Nature methods\| PubMed ID: 17572681	2007
The zebra fish cassiopeia mutant reveals that SIL is required for mitotic spindle organization. Molecular and cellular biology\| PubMed ID: 17576815	2007
Functional conservation of erythropoietin signaling in zebrafish. Blood\| PubMed ID: 17579187	2007
Prostaglandin E2 regulates vertebrate haematopoietic stem cell homeostasis. Nature\| PubMed ID: 17581586	2007
Definition of the zebrafish genome using flow cytometry and cytogenetic mapping. BMC genomics\| PubMed ID: 17597531	2007
The zebrafish runzel muscular dystrophy is linked to the titin gene. Developmental biology\| PubMed ID: 17678642	2007
Duplicate VegfA genes and orthologues of the KDR receptor tyrosine kinase family mediate vascular development in the zebrafish. Blood\| PubMed ID: 17698971	2007
Generation and characterization of transgenic zebrafish lines using different ubiquitous promoters. Transgenic research\| PubMed ID: 17968670	2008
APC and colon cancer: two hits for one. Nature medicine\| PubMed ID: 17987022	2007
Prostaglandin E2: making more of your marrow. Cell cycle (Georgetown, Tex.)\| PubMed ID: 18075310	2007
Combinatorial regulation of novel erythroid gene expression in zebrafish. Experimental hematology\| PubMed ID: 18243489	2008
Taking human cancer genes to the fish: a transgenic model of melanoma in zebrafish. Zebrafish\| PubMed ID: 18248215	2005
Hematopoiesis: an evolving paradigm for stem cell biology. Cell\| PubMed ID: 18295580	2008
SnapShot: hematopoiesis. Cell\| PubMed ID: 18295585	2008
Minimum information specification for in situ hybridization and immunohistochemistry experiments (MISFISHIE). Nature biotechnology\| PubMed ID: 18327244	2008
Cell stem cell. Cell stem cell\| PubMed ID: 18371324	2007
Teratoma formation assays with human embryonic stem cells: a rationale for one type of human-animal chimera. Cell stem cell\| PubMed ID: 18371359	2007
BMP and Wnt specify hematopoietic fate by activation of the Cdx-Hox pathway. Cell stem cell\| PubMed ID: 18371423	2008
Transparent adult zebrafish as a tool for in vivo transplantation analysis. Cell stem cell\| PubMed ID: 18371439	2008
Use of zebrafish models for the analysis of human disease. Current protocols in human genetics / editorial board, Jonathan L. Haines ... [et al.]\| PubMed ID: 18428328	2002
Intrinsic and extrinsic control of haematopoietic stem-cell self-renewal. Nature\| PubMed ID: 18480811	2008
Zebrafish VEGF receptors: a guideline to nomenclature. PLoS genetics\| PubMed ID: 18516225	2008
Self-renewal and differentiation at Cell Stem Cell. Cell stem cell\| PubMed ID: 18522838	2008
montalcino, A zebrafish model for variegate porphyria. Experimental hematology\| PubMed ID: 18550261	2008
APC mutant zebrafish uncover a changing temporal requirement for wnt signaling in liver development. Developmental biology\| PubMed ID: 18585699	2008
Zebrafish mutants with disrupted early T-cell and thymus development identified in early pressure screen. Developmental dynamics : an official publication of the American Association of Anatomists\| PubMed ID: 18729230	2008
Melanocytes in development, regeneration, and cancer. Cell stem cell\| PubMed ID: 18786412	2008
Eya4 regulation of Na+/K+-ATPase is required for sensory system development in zebrafish. Development (Cambridge, England)\| PubMed ID: 18799547	2008
Intestinal differentiation in zebrafish requires Cdx1b, a functional equivalent of mammalian Cdx2. Gastroenterology\| PubMed ID: 18804112	2008
A non-canonical function of zebrafish telomerase reverse transcriptase is required for developmental hematopoiesis. PloS one\| PubMed ID: 18846223	2008
Construction and application of a zebrafish array comparative genomic hybridization platform. Genes, chromosomes & cancer\| PubMed ID: 18973135	2009
Transferrin-a modulates hepcidin expression in zebrafish embryos. Blood\| PubMed ID: 19047682	2009
Abnormal nuclear pore formation triggers apoptosis in the intestinal epithelium of elys-deficient zebrafish. Gastroenterology\| PubMed ID: 19073184	2009
Melanoma biology and the promise of zebrafish. Zebrafish\| PubMed ID: 19133823	2008
The effect of a depth gradient on the mating behavior, oviposition site preference, and embryo production in the zebrafish, Danio rerio. Zebrafish\| PubMed ID: 19133832	2008
Genetic interaction of PGE2 and Wnt signaling regulates developmental specification of stem cells and regeneration. Cell\| PubMed ID: 19303855	2009
A genetic screen in zebrafish defines a hierarchical network of pathways required for hematopoietic stem cell emergence. Blood\| PubMed ID: 19332767	2009
Topoisomerase II alpha is required for embryonic development and liver regeneration in zebrafish. Molecular and cellular biology\| PubMed ID: 19380487	2009
Zebrafish kidney stromal cell lines support multilineage hematopoiesis. Blood\| PubMed ID: 19433857	2009
Hematopoietic stem cell development is dependent on blood flow. Cell\| PubMed ID: 19450519	2009
Zebrafish blood stem cells. Journal of cellular biochemistry\| PubMed ID: 19565566	2009
Defining cancer stem cells by xenotransplantation in zebrafish. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 19582417	2009
Chemical genetic screening in the zebrafish embryo. Nature protocols\| PubMed ID: 19745824	2009
Melanocytes in development and cancer. Journal of cellular physiology\| PubMed ID: 19795394	2010
Oncogenic NRAS cooperates with p53 loss to generate melanoma in zebrafish. Zebrafish\| PubMed ID: 19954345	2009
Zebrafish tumor assays: the state of transplantation. Zebrafish\| PubMed ID: 20047467	2009
High-throughput cell transplantation establishes that tumor-initiating cells are abundant in zebrafish T-cell acute lymphoblastic leukemia. Blood\| PubMed ID: 20056790	2010
Derivation of adult stem cells during embryogenesis. Harvey lectures\| PubMed ID: 20166566	2006
Swimming into the future of drug discovery: in vivo chemical screens in zebrafish. ACS chemical biology\| PubMed ID: 20166761	2010
Resolving the controversy about N-cadherin and hematopoietic stem cells. Cell stem cell\| PubMed ID: 20207222	2010
Small molecule screen in zebrafish and HSC expansion. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 20336531	2010
The Wnt/beta-catenin pathway is required for the development of leukemia stem cells in AML. Science (New York, N.Y.)\| PubMed ID: 20339075	2010
Interaction of retinoic acid and scl controls primitive blood development. Blood\| PubMed ID: 20410509	2010
The new age of chemical screening in zebrafish. Zebrafish\| PubMed ID: 20415642	2010
A chemical genetic screen in zebrafish for pathways interacting with cdx4 in primitive hematopoiesis. Zebrafish\| PubMed ID: 20415644	2010
Newly emerging roles for prostaglandin E2 regulation of hematopoiesis and hematopoietic stem cell engraftment. Current opinion in hematology\| PubMed ID: 20473159	2010
Cdx4 is dispensable for murine adult hematopoietic stem cells but promotes MLL-AF9-mediated leukemogenesis. Haematologica\| PubMed ID: 20494928	2010
TIF1gamma controls erythroid cell fate by regulating transcription elongation. Cell\| PubMed ID: 20603019	2010
Blood flow: metalloproteases cut loose in primitive erythrocytes. Current biology : CB\| PubMed ID: 20619808	2010
Fishing at the cellular level. Nature methods\| PubMed ID: 20676080	2010
Zebrafish models of p53 functions. Cold Spring Harbor perspectives in biology\| PubMed ID: 20679337	2010
Hematopoietic development in the zebrafish. The International journal of developmental biology\| PubMed ID: 20711990	2010
PGE2-regulated wnt signaling and N-acetylcysteine are synergistically hepatoprotective in zebrafish acetaminophen injury. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 20855591	2010
T-lymphoblastic lymphoma cells express high levels of BCL2, S1P1, and ICAM1, leading to a blockade of tumor cell intravasation. Cancer cell\| PubMed ID: 20951945	2010
The zebrafish: cellular and developmental biology, part A. Preface. Methods in cell biology\| PubMed ID: 21111211	2010
Stem cells: The blood balance. Nature\| PubMed ID: 21124447	2010
Ubiquitous transgene expression and Cre-based recombination driven by the ubiquitin promoter in zebrafish. Development (Cambridge, England)\| PubMed ID: 21138979	2011
Lessons from the Niche for Generation and Expansion of Hematopoietic Stem Cells. Drug discovery today. Therapeutic strategies\| PubMed ID: 21212834	2009
The zebrafish dag1 mutant: a novel genetic model for dystroglycanopathies. Human molecular genetics\| PubMed ID: 21296866	2011
The ERGonomics of hematopoietic stem cell self-renewal. Genes & development\| PubMed ID: 21325129	2011
cpsf1 is required for definitive HSC survival in zebrafish. Blood\| PubMed ID: 21330472	2011
Isolation and transcriptome analysis of adult zebrafish cells enriched for skeletal muscle progenitors. Muscle & nerve\| PubMed ID: 21337346	2011
Characterization of immune-matched hematopoietic transplantation in zebrafish. Blood\| PubMed ID: 21346254	2011
Clonal analysis of hematopoietic progenitor cells in the zebrafish. Blood\| PubMed ID: 21415264	2011
The histone methyltransferase SETDB1 is recurrently amplified in melanoma and accelerates its onset. Nature\| PubMed ID: 21430779	2011
DHODH modulates transcriptional elongation in the neural crest and melanoma. Nature\| PubMed ID: 21430780	2011
Modeling Diamond Blackfan anemia in the zebrafish. Seminars in hematology\| PubMed ID: 21435504	2011
Prostaglandin E2 enhances human cord blood stem cell xenotransplants and shows long-term safety in preclinical nonhuman primate transplant models. Cell stem cell\| PubMed ID: 21474107	2011
Stem cell migration: a zebrafish model. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 21618090	2011
Stromal cell-derived factor-1 and hematopoietic cell homing in an adult zebrafish model of hematopoietic cell transplantation. Blood\| PubMed ID: 21622651	2011
Zebrafish as a model for normal and malignant hematopoiesis. Disease models & mechanisms\| PubMed ID: 21708900	2011
A new system for the rapid collection of large numbers of developmentally staged zebrafish embryos. PloS one\| PubMed ID: 21738776	2011
Genetic suppressor screens in haploids. Methods in cell biology\| PubMed ID: 21924160	2011
Advanced zebrafish transgenesis with Tol2 and application for Cre/lox recombination experiments. Methods in cell biology\| PubMed ID: 21924163	2011
The zon laboratory guide to positional cloning in zebrafish. Methods in cell biology\| PubMed ID: 21924169	2011
Chromatin immunoprecipitation in adult zebrafish red cells. Methods in cell biology\| PubMed ID: 21924172	2011
The NOTCH pathway contributes to cell fate decision in myelopoiesis. Haematologica\| PubMed ID: 21933862	2011
Transplantation in zebrafish. Methods in cell biology\| PubMed ID: 21951540	2011
Chemical screening in zebrafish for novel biological and therapeutic discovery. Methods in cell biology\| PubMed ID: 21951544	2011
Lineage regulators direct BMP and Wnt pathways to cell-specific programs during differentiation and regeneration. Cell\| PubMed ID: 22036566	2011
The zebrafish. Preface. Methods in cell biology\| PubMed ID: 22043535	2011
Hematopoietic defects in rps29 mutant zebrafish depend upon p53 activation. Experimental hematology\| PubMed ID: 22120640	2012
An optical platform for cell tracking in adult zebrafish. Cytometry. Part A : the journal of the International Society for Analytical Cytology\| PubMed ID: 22162445	2012
Extensive genetic diversity and substructuring among zebrafish strains revealed through copy number variant analysis. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 22203992	2012
Hematopoietic stem cells, hematopoiesis and disease: lessons from the zebrafish model. Genome medicine\| PubMed ID: 22206610	2011
Linking hematopoietic regeneration to developmental signaling pathways: A story of BMP and Wnt. Cell cycle (Georgetown, Tex.)\| PubMed ID: 22262185	2012
Stem cells: The right neighbour. Nature\| PubMed ID: 22281591	2012
Direct recruitment of polycomb repressive complex 1 to chromatin by core binding transcription factors. Molecular cell\| PubMed ID: 22325351	2012
Nanog-like regulates endoderm formation through the Mxtx2-Nodal pathway. Developmental cell\| PubMed ID: 22421047	2012
Zebrafish globin switching occurs in two developmental stages and is controlled by the LCR. Developmental biology\| PubMed ID: 22537494	2012
A great match. Cell stem cell\| PubMed ID: 22704496	2012
Hooked! Modeling human disease in zebrafish. The Journal of clinical investigation\| PubMed ID: 22751109	2012
Histocompatibility and hematopoietic transplantation in the zebrafish. Advances in hematology\| PubMed ID: 22778744	2012
Cancer and inflammation: an aspirin a day keeps the cancer at bay. Current biology : CB\| PubMed ID: 22789999	2012
Formation of a PKCζ/β-catenin complex in endothelial cells promotes angiopoietin-1-induced collective directional migration and angiogenic sprouting. Blood\| PubMed ID: 22936663	2012
Ccdc94 protects cells from ionizing radiation by inhibiting the expression of p53. PLoS genetics\| PubMed ID: 22952453	2012
A splice site mutation in laminin-α2 results in a severe muscular dystrophy and growth abnormalities in zebrafish. PloS one\| PubMed ID: 22952766	2012
Teleost growth factor independence (gfi) genes differentially regulate successive waves of hematopoiesis. Developmental biology\| PubMed ID: 22960038	2013
Loss of 5-hydroxymethylcytosine is an epigenetic hallmark of melanoma. Cell\| PubMed ID: 22980977	2012
In situ hybridization assay-based small molecule screening in zebrafish. Current protocols in chemical biology\| PubMed ID: 23001521	2012
CHMP1A encodes an essential regulator of BMI1-INK4A in cerebellar development. Nature genetics\| PubMed ID: 23023333	2012
The transcriptional landscape of hematopoietic stem cell ontogeny. Cell stem cell\| PubMed ID: 23122293	2012
TiF1-gamma plays an essential role in murine hematopoiesis and regulates transcriptional elongation of erythroid genes. Developmental biology\| PubMed ID: 23159334	2013
Phospholipase C gamma-1 is required for granulocyte maturation in zebrafish. Developmental biology\| PubMed ID: 23220656	2013
Signaling axis involving Hedgehog, Notch, and Scl promotes the embryonic endothelial-to-hematopoietic transition. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23236128	2013
Ageing: Stem cells on a stress-busting diet. Nature\| PubMed ID: 23389448	2013
Potential of zebrafish for anticancer drug screening. Expert opinion on drug discovery\| PubMed ID: 23506108	2008
A model for primary melanoma of the CNS implicates NRAS. Cancer discovery\| PubMed ID: 23580282	2013
The zebrafish reference genome sequence and its relationship to the human genome. Nature\| PubMed ID: 23594743	2013
A novel chemical screening strategy in zebrafish identifies common pathways in embryogenesis and rhabdomyosarcoma development. Development (Cambridge, England)\| PubMed ID: 23615277	2013
The histone methyltransferase SUV39H1 suppresses embryonal rhabdomyosarcoma formation in zebrafish. PloS one\| PubMed ID: 23705022	2013
Hematopoiesis. Development (Cambridge, England)\| PubMed ID: 23715539	2013
Site-directed zebrafish transgenesis into single landing sites with the phiC31 integrase system. Developmental dynamics : an official publication of the American Association of Anatomists\| PubMed ID: 23723152	2013
Small molecule screening in zebrafish: swimming in potential drug therapies. Wiley interdisciplinary reviews. Developmental biology\| PubMed ID: 23801494	2012
Zebrafish rhabdomyosarcoma reflects the developmental stage of oncogene expression during myogenesis. Development (Cambridge, England)\| PubMed ID: 23821038	2013
Assaying hematopoiesis using zebrafish. Blood cells, molecules & diseases\| PubMed ID: 23916372	2013
Zebrafish cancer: the state of the art and the path forward. Nature reviews. Cancer\| PubMed ID: 23969693	2013
Prostaglandin-modulated umbilical cord blood hematopoietic stem cell transplantation. Blood\| PubMed ID: 23996087	2013
Induction of multipotential hematopoietic progenitors from human pluripotent stem cells via respecification of lineage-restricted precursors. Cell stem cell\| PubMed ID: 24094326	2013
The zebrafish granulocyte colony stimulating factors (Gcsfs): two paralogous cytokines and their roles in hematopoietic development and maintenance. Blood\| PubMed ID: 24128862	2013
The genetic heterogeneity and mutational burden of engineered melanomas in zebrafish models. Genome biology\| PubMed ID: 24148783	2013
zebraflash transgenic lines for in vivo bioluminescence imaging of stem cells and regeneration in adult zebrafish. Development (Cambridge, England)\| PubMed ID: 24198277	2013
A zebrafish embryo culture system defines factors that promote vertebrate myogenesis across species. Cell\| PubMed ID: 24209627	2013
A network of epigenetic regulators guides developmental haematopoiesis in vivo. Nature cell biology\| PubMed ID: 24240475	2013
Of fish and men: using zebrafish to fight human diseases. Trends in cell biology\| PubMed ID: 24275383	2013
A Cdx4-Sall4 regulatory module controls the transition from mesoderm formation to embryonic hematopoiesis. Stem cell reports\| PubMed ID: 24286030	2013
Novel cardiovascular gene functions revealed via systematic phenotype prediction in zebrafish. Development (Cambridge, England)\| PubMed ID: 24346703	2014
A non-canonical function of telomerase RNA in the regulation of developmental myelopoiesis in zebrafish. Nature communications\| PubMed ID: 24496182	2014
Tissue specific roles for the ribosome biogenesis factor Wdr43 in zebrafish development. PLoS genetics\| PubMed ID: 24497835	2014
Translational research: the path for bringing discovery to patients. Cell stem cell\| PubMed ID: 24506882	2014
Unexpectedly uneven: posttransplant skeletal distribution of hematopoietic stem cell clones. The Journal of experimental medicine\| PubMed ID: 24616474	2014
Mutations in QARS, encoding glutaminyl-tRNA synthetase, cause progressive microcephaly, cerebral-cerebellar atrophy, and intractable seizures. American journal of human genetics\| PubMed ID: 24656866	2014
Neural crest development and craniofacial morphogenesis is coordinated by nitric oxide and histone acetylation. Chemistry & biology\| PubMed ID: 24684905	2014
Whole-exome sequencing and functional studies identify RPS29 as a novel gene mutated in multicase Diamond-Blackfan anemia families. Blood\| PubMed ID: 24829207	2014
Dissection of vertebrate hematopoiesis using zebrafish thrombopoietin. Blood\| PubMed ID: 24869937	2014
From fish tank to bedside in cancer therapy: an interview with Leonard Zon. Disease models & mechanisms\| PubMed ID: 24973742	2014
Intrinsic expression of a multiexon type 3 deiodinase gene controls zebrafish embryo size. Endocrinology\| PubMed ID: 25004091	2014
Getting more for your marrow: boosting hematopoietic stem cell numbers with PGE2. Experimental cell research\| PubMed ID: 25094063	2014
Selective microRNA uridylation by Zcchc6 (TUT7) and Zcchc11 (TUT4). Nucleic acids research\| PubMed ID: 25223788	2014
A comparison of non-integrating reprogramming methods. Nature biotechnology\| PubMed ID: 25437882	2015
A zebrafish model of myelodysplastic syndrome produced through tet2 genomic editing. Molecular and cellular biology\| PubMed ID: 25512612	2015
Notch1 acts via Foxc2 to promote definitive hematopoiesis via effects on hemogenic endothelium. Blood\| PubMed ID: 25587036	2015
Hematopoietic stem cell arrival triggers dynamic remodeling of the perivascular niche. Cell\| PubMed ID: 25594182	2015
Angiopoietin-like proteins stimulate HSPC development through interaction with notch receptor signaling. eLife\| PubMed ID: 25714926	2015
A CRISPR/Cas9 Vector System for Tissue-Specific Gene Disruption in Zebrafish. Developmental cell\| PubMed ID: 25752963	2015
Screening for melanoma resistance genes in vivo. Pigment cell & melanoma research\| PubMed ID: 25818368	2015