Department of Biological Sciences,
Dornsife College of Letters,
Arts,
and Sciences,
Norris Comprehensive Cancer Center,
Keck School of Medicine,
Department of Biochemistry and Molecular Medicine
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High definition profiling of mammalian DNA methylation by array capture and single molecule bisulfite sequencing.
Genome research Sep, 2009 | Pubmed ID: 19581485
Updates to the RMAP short-read mapping software.
Bioinformatics (Oxford, England) Nov, 2009 | Pubmed ID: 19736251
The maize methylome influences mRNA splice sites and reveals widespread paramutation-like switches guided by small RNA.
Genome research Oct, 2013 | Pubmed ID: 23739895
Rapid phenotypic and genomic change in response to therapeutic pressure in prostate cancer inferred by high content analysis of single circulating tumor cells.
PloS one , 2014 | Pubmed ID: 25084170
Limited genomic heterogeneity of circulating melanoma cells in advanced stage patients.
Physical biology Jan, 2015 | Pubmed ID: 25574741
Paired High-Content Analysis of Prostate Cancer Cells in Bone Marrow and Blood Characterizes Increased Androgen Receptor Expression in Tumor Cell Clusters.
Clinical cancer research : an official journal of the American Association for Cancer Research Apr, 2017 | Pubmed ID: 27702818
Vasculogenic mimicry in small cell lung cancer.
Nature communications 11, 2016 | Pubmed ID: 27827359
TGF-β reduces DNA ds-break repair mechanisms to heighten genetic diversity and adaptability of CD44+/CD24- cancer cells.
eLife 01, 2017 | Pubmed ID: 28092266
Whole-genome single-cell copy number profiling from formalin-fixed paraffin-embedded samples.
Nature medicine Mar, 2017 | Pubmed ID: 28165479
Unravelling biology and shifting paradigms in cancer with single-cell sequencing.
Nature reviews. Cancer 08, 2017 | Pubmed ID: 28835719
Potential of Aqueous Humor as a Surrogate Tumor Biopsy for Retinoblastoma.
JAMA ophthalmology , | Pubmed ID: 29049475
Effect of Blood Collection Tube Type and Time to Processing on the Enumeration and High-Content Characterization of Circulating Tumor Cells Using the High-Definition Single-Cell Assay.
Archives of pathology & laboratory medicine Feb, 2018 | Pubmed ID: 29144792
Potential of Aqueous Humor as a Surrogate Tumor Biopsy for Retinoblastoma-Reply.
JAMA ophthalmology 05, 2018 | Pubmed ID: 29566117
When it comes to genomic analysis of tumours, don't buy in bulk.
British journal of cancer 05, 2018 | Pubmed ID: 29743553
Opportunities to implement a sustainable genomic medicine program: lessons learned from the IGNITE Network.
Genetics in medicine : official journal of the American College of Medical Genetics 03, 2019 | Pubmed ID: 29997387
Improved molecular karyotyping in glioblastoma.
Mutation research 09, 2018 | Pubmed ID: 30055482
Single-cell RNA-seq analysis identifies markers of resistance to targeted BRAF inhibitors in melanoma cell populations.
Genome research 09, 2018 | Pubmed ID: 30061114
Genomic cfDNA Analysis of Aqueous Humor in Retinoblastoma Predicts Eye Salvage: The Surrogate Tumor Biopsy for Retinoblastoma.
Molecular cancer research : MCR , | Pubmed ID: 30061186
Correction: Opportunities to implement a sustainable genomic medicine program: lessons learned from the IGNITE Network.
Genetics in medicine : official journal of the American College of Medical Genetics Jul, 2019 | Pubmed ID: 30158693
Single-Cell Applications of Next-Generation Sequencing.
Cold Spring Harbor perspectives in medicine 10, 2019 | Pubmed ID: 30617056
Single-Cell Analysis of Circulating Tumor Cells.
Methods in molecular biology (Clifton, N.J.) , 2019 | Pubmed ID: 30649733
Multiplex protein detection on circulating tumor cells from liquid biopsies using imaging mass cytometry.
Convergent science physical oncology Mar, 2018 | Pubmed ID: 30906572
SMURF-seq: efficient copy number profiling on long-read sequencers.
Genome biology 07, 2019 | Pubmed ID: 31287019
Circulating tumor cells as a response monitor in stage IV non-small cell lung cancer.
Journal of translational medicine 08, 2019 | Pubmed ID: 31462312
Circulating Tumor Cells Exhibit Metastatic Tropism and Reveal Brain Metastasis Drivers.
Cancer discovery 01, 2020 | Pubmed ID: 31601552
Aqueous Humor Is Superior to Blood as a Liquid Biopsy for Retinoblastoma.
Ophthalmology , | Pubmed ID: 31767439
A truncating mutation in the autophagy gene UVRAG drives inflammation and tumorigenesis in mice.
Nature communications 12, 2019 | Pubmed ID: 31831743
Single cell correlation analysis of liquid and solid biopsies in metastatic colorectal cancer.
Oncotarget Dec, 2019 | Pubmed ID: 31903162
Preanalytical Variables for the Genomic Assessment of the Cellular and Acellular Fractions of the Liquid Biopsy in a Cohort of Breast Cancer Patients.
The Journal of molecular diagnostics : JMD 03, 2020 | Pubmed ID: 31978562
Minimum Technical Data Elements for Liquid Biopsy Data Submitted to Public Databases.
Clinical pharmacology and therapeutics 04, 2020 | Pubmed ID: 32017048
Whole-Exome Sequencing Analysis of the Progression from Non-Low-Grade Ductal Carcinoma to Invasive Ductal Carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 07, 2020 | Pubmed ID: 32220886
Single-Cell Circulating Tumor Cell Analysis Reveals Genomic Instability as a Distinctive Feature of Aggressive Prostate Cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 08, 2020 | Pubmed ID: 32341031
Variability in retinoblastoma genome stability is driven by age and not heritability.
Genes, chromosomes & cancer , | Pubmed ID: 32390242
Chromosome 6p Amplification in Aqueous Humor Cell-Free DNA Is a Prognostic Biomarker for Retinoblastoma Ocular Survival.
Molecular cancer research : MCR , | Pubmed ID: 32434859
Liquid Biopsy in Colorectal Carcinoma: Clinical Applications and Challenges.
Cancers May, 2020 | Pubmed ID: 32471160
Clonal diversity revealed by morphoproteomic and copy number profiles of single prostate cancer cells at diagnosis.
Convergent science physical oncology Mar, 2018 | Pubmed ID: 32670616
Correction: Opportunities to implement a sustainable genomic medicine program: lessons learned from the IGNITE Network.
Genetics in medicine : official journal of the American College of Medical Genetics Oct, 2020 | Pubmed ID: 32719393
Simultaneous identification of clinically relevant mutations and copy number alterations in aqueous humor of retinoblastoma eyes.
Ophthalmic genetics , | Pubmed ID: 32799607
Author Correction: SMURF-seq: efficient copy number profiling on long-read sequencers.
Genome biology Aug, 2020 | Pubmed ID: 32843071
Generic Protocols for the Analytical Validation of Next-Generation Sequencing-Based ctDNA Assays: A Joint Consensus Recommendation of the BloodPAC's Analytical Variables Working Group.
Clinical chemistry 09, 2020 | Pubmed ID: 32870995
Modeling the Onset of Symptoms of COVID-19.
Frontiers in public health , 2020 | Pubmed ID: 32903584
Cell-Free DNA Tumor Fraction in the Aqueous Humor Is Associated With Therapeutic Response in Retinoblastoma Patients.
Translational vision science & technology 09, 2020 | Pubmed ID: 33062393
Treatment response and tumor evolution: lessons from an extended series of multianalyte liquid biopsies in a metastatic breast cancer patient.
Cold Spring Harbor molecular case studies 12, 2020 | Pubmed ID: 33203646
Correction: Opportunities to implement a sustainable genomic medicine program: lessons learned from the IGNITE Network.
Genetics in medicine : official journal of the American College of Medical Genetics Dec, 2020 | Pubmed ID: 33288881
N-Acetyl-L-cysteine Promotes Growth and Expansion of Single Circulating Tumor Cells by Mitigating Cellular Stress Responses.
Molecular cancer research : MCR 03, 2021 | Pubmed ID: 33303691
Large Extracellular Vesicle Characterization and Association with Circulating Tumor Cells in Metastatic Castrate Resistant Prostate Cancer.
Cancers Mar, 2021 | Pubmed ID: 33801459
Establishing the Clinical Utility of ctDNA Analysis for Diagnosis, Prognosis, and Treatment Monitoring of Retinoblastoma: The Aqueous Humor Liquid Biopsy.
Cancers Mar, 2021 | Pubmed ID: 33805776
Comprehensive Somatic Copy Number Analysis Using Aqueous Humor Liquid Biopsy for Retinoblastoma.
Cancers Jul, 2021 | Pubmed ID: 34283049
Inter-eye genomic heterogeneity in bilateral retinoblastoma via aqueous humor liquid biopsy.
NPJ precision oncology Jul, 2021 | Pubmed ID: 34316014
Platelet-coated circulating tumor cells are a predictive biomarker in patients with metastatic castrate resistant prostate cancer.
Molecular cancer research : MCR Aug, 2021 | Pubmed ID: 34462330
Mary E. Kim1,2,
Liya Xu1,2,3,11,
Rishvanth K. Prabakar4,
Lishuang Shen5,
Chen-Ching Peng1,3,
Peter Kuhn3,6,7,8,
Xiaowu Gai5,9,
James Hicks3,6,10,
Jesse L. Berry1,2,6,11
1The Vision Center, Children’s Hospital Los Angeles,
2USC Roski Eye Institute, Keck School of Medicine of the University of Southern California,
3Department of Biological Sciences, Dornsife College of Letters, Arts, and Sciences, University of Southern California,
4Department of Molecular and Computational Biology, University of Southern California,
5Center for Personalized Medicine, Department of Pathology and Laboratory Medicine, Children’s Hospital Los Angeles,
6Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California,
7Department of Aerospace and Mechanical Engineering, Viterbi School of Engineering, University of Southern California,
8Department of Biomedical Engineering, Viterbi School of Engineering, University of Southern California,
9Department of Pathology and Laboratory Medicine, Keck School of Medicine of USC,
10Department of Biochemistry and Molecular Medicine, Keck School of Medicine, University of Southern California,
11The Saban Research Institute, Children’s Hospital Los Angeles
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