Department of Pharmacology and Chemical Biology
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Adenosine-mediated inhibition of the cytotoxic activity and cytokine production by activated natural killer cells.
Cancer research Aug, 2006 | Pubmed ID: 16885379
Sex hormones and hypertension.
Cardiovascular research Feb, 2002 | Pubmed ID: 11861040
A(2B) adenosine receptors stimulate growth of porcine and rat arterial endothelial cells.
Hypertension (Dallas, Tex. : 1979) Feb, 2002 | Pubmed ID: 11882603
Long-term caffeine consumption exacerbates renal failure in obese, diabetic, ZSF1 (fa-fa(cp)) rats.
Kidney international Apr, 2002 | Pubmed ID: 11918750
Catecholamines block 2-hydroxyestradiol-induced antimitogenesis in mesangial cells.
Hypertension (Dallas, Tex. : 1979) Apr, 2002 | Pubmed ID: 11967239
Expression of adenosine receptors in the preglomerular microcirculation.
American journal of physiology. Renal physiology Jul, 2002 | Pubmed ID: 12060585
Administration of adenosine receptor agonists or antagonists after controlled cortical impact in mice: effects on function and histopathology.
Brain research Oct, 2002 | Pubmed ID: 12270497
2-Hydroxyestradiol attenuates renal disease in chronic puromycin aminonucleoside nephropathy.
Journal of the American Society of Nephrology : JASN Nov, 2002 | Pubmed ID: 12397044
alpha 2-Adrenoceptors potentiate angiotensin II- and vasopressin-induced renal vasoconstriction in spontaneously hypertensive rats.
The Journal of pharmacology and experimental therapeutics May, 2003 | Pubmed ID: 12606648
Role of EGFR transactivation in angiotensin II signaling to extracellular regulated kinase in preglomerular smooth muscle cells.
Hypertension (Dallas, Tex. : 1979) Mar, 2003 | Pubmed ID: 12623996
Type IV phosphodiesterase inhibition improves cardiac contractility in endotoxemic rats.
European journal of pharmacology Mar, 2003 | Pubmed ID: 12650842
Oviduct cells express the cyclic AMP-adenosine pathway.
Biology of reproduction Sep, 2003 | Pubmed ID: 12724271
Methylation of 2-hydroxyestradiol in isolated organs.
Hypertension (Dallas, Tex. : 1979) Jul, 2003 | Pubmed ID: 12771046
Rat models of the metabolic syndrome.
Methods in molecular medicine , 2003 | Pubmed ID: 12886760
Renal extraction of angiotensin II.
The Journal of pharmacology and experimental therapeutics Dec, 2003 | Pubmed ID: 14534364
Adenosine biosynthesis in the collecting duct.
The Journal of pharmacology and experimental therapeutics Dec, 2003 | Pubmed ID: 14560043
Methoxyestradiols mediate the antimitogenic effects of 17beta-estradiol: direct evidence from catechol-O-methyltransferase-knockout mice.
Circulation Dec, 2003 | Pubmed ID: 14662705
AT2 receptors attenuate AT1 receptor-induced phospholipase D activation in vascular smooth muscle cells.
The Journal of pharmacology and experimental therapeutics Apr, 2004 | Pubmed ID: 14722318
2-hydroxyestradiol is a prodrug of 2-methoxyestradiol.
The Journal of pharmacology and experimental therapeutics Jun, 2004 | Pubmed ID: 14872091
The extracellular cyclic AMP-adenosine pathway in renal physiology.
Annual review of physiology , 2004 | Pubmed ID: 14977414
Vascular endothelial growth factor is increased in cerebrospinal fluid after traumatic brain injury in infants and children.
Neurosurgery Mar, 2004 | Pubmed ID: 15028134
Modulation of cyclic AMP production by signal transduction pathways in preglomerular microvessels and microvascular smooth muscle cells.
The Journal of pharmacology and experimental therapeutics Jul, 2004 | Pubmed ID: 15087474
A gas chromatography/mass spectrometry assay to measure estradiol, catecholestradiols, and methoxyestradiols in plasma.
Steroids Apr, 2004 | Pubmed ID: 15183691
Increased expression of the sodium transporter BSC-1 in spontaneously hypertensive rats.
The Journal of pharmacology and experimental therapeutics Dec, 2004 | Pubmed ID: 15340004
Continuous versus intermittent cerebrospinal fluid drainage after severe traumatic brain injury in children: effect on biochemical markers.
Journal of neurotrauma Sep, 2004 | Pubmed ID: 15453982
Hormone replacement therapy and cardiovascular disease: what went wrong and where do we go from here?
Hypertension (Dallas, Tex. : 1979) Dec, 2004 | Pubmed ID: 15477384
Intraperitoneal administration of adenosine inhibits formation of abdominal adhesions.
Diseases of the colon and rectum Aug, 2004 | Pubmed ID: 15484355
Enhanced activation of RhoA by angiotensin II in SHR preglomerular microvascular smooth muscle cells.
Journal of cardiovascular pharmacology Apr, 2005 | Pubmed ID: 15772513
Vascular consequences of menopause and hormone therapy: importance of timing of treatment and type of estrogen.
Cardiovascular research May, 2005 | Pubmed ID: 15820198
Mechanism of the vascular angiotensin II/alpha2-adrenoceptor interaction.
The Journal of pharmacology and experimental therapeutics Sep, 2005 | Pubmed ID: 15901799
Characterization of the effects of adenosine receptor agonists on cerebral blood flow in uninjured and traumatically injured rat brain using continuous arterial spin-labeled magnetic resonance imaging.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism Dec, 2005 | Pubmed ID: 15931163
Estradiol metabolites attenuate renal and cardiovascular injury induced by chronic nitric oxide synthase inhibition.
Journal of cardiovascular pharmacology Jul, 2005 | Pubmed ID: 15965351
Adenosine inhibits PDGF-induced growth of human glomerular mesangial cells via A(2B) receptors.
Hypertension (Dallas, Tex. : 1979) Sep, 2005 | Pubmed ID: 16103269
Adenosine A1 receptor knockout mice develop lethal status epilepticus after experimental traumatic brain injury.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism Apr, 2006 | Pubmed ID: 16121125
Estradiol metabolites attenuate monocrotaline-induced pulmonary hypertension in rats.
Journal of cardiovascular pharmacology Oct, 2005 | Pubmed ID: 16160593
Gs protein-coupled adenosine receptor signaling and lytic function of activated NK cells.
Journal of immunology (Baltimore, Md. : 1950) Oct, 2005 | Pubmed ID: 16177079
Pancreatic polypeptide-fold peptide receptors and angiotensin II-induced renal vasoconstriction.
Hypertension (Dallas, Tex. : 1979) Mar, 2006 | Pubmed ID: 16365188
cAMP-adenosine pathway in the proximal tubule.
The Journal of pharmacology and experimental therapeutics Jun, 2006 | Pubmed ID: 16527902
Role of renal sympathetic nerves in regulating renovascular responses to angiotensin II in spontaneously hypertensive rats.
The Journal of pharmacology and experimental therapeutics Jun, 2006 | Pubmed ID: 16537795
2-Methoxyestradiol mediates the protective effects of estradiol in monocrotaline-induced pulmonary hypertension.
Vascular pharmacology Dec, 2006 | Pubmed ID: 16872912
A2A adenosine receptor protects tumors from antitumor T cells.
Proceedings of the National Academy of Sciences of the United States of America Aug, 2006 | Pubmed ID: 16916931
Conversion of tibolone to 7alpha-methyl-ethinyl estradiol using gas chromatography-mass spectrometry and liquid chromatography-mass spectrometry: interpretation and clinical implications.
Menopause (New York, N.Y.) Nov-Dec, 2006 | Pubmed ID: 17006378
The extracellular cAMP-adenosine pathway significantly contributes to the in vivo production of adenosine.
The Journal of pharmacology and experimental therapeutics Jan, 2007 | Pubmed ID: 17028245
2-Methoxyestradiol and 2-ethoxyestradiol retard the progression of renal disease in aged, obese, diabetic ZSF1 rats.
Journal of cardiovascular pharmacology Jan, 2007 | Pubmed ID: 17261964
PPAR alpha agonists improve renal preservation in kidneys subjected to chronic in vitro perfusion: interaction with mannitol.
Transplant international : official journal of the European Society for Organ Transplantation Mar, 2007 | Pubmed ID: 17291221
Characterization of renal ecto-phosphodiesterase.
The Journal of pharmacology and experimental therapeutics May, 2007 | Pubmed ID: 17308037
Phospholipase C and Src modulate angiotensin II-induced cyclic AMP production in preglomerular microvascular smooth-muscle cells from spontaneously hypertensive rats.
Journal of cardiovascular pharmacology Feb, 2007 | Pubmed ID: 17312452
The pancreatohepatorenal cAMP-adenosine mechanism.
The Journal of pharmacology and experimental therapeutics May, 2007 | Pubmed ID: 17314200
Adenosine-mediated inhibition of cytotoxic activity and cytokine production by IL-2/NKp46-activated NK cells: involvement of protein kinase A isozyme I (PKA I).
Immunologic research , 2006 | Pubmed ID: 17337770
Norepinephrine, via beta-adrenoceptors, regulates bumetanide-sensitive cotransporter type 1 expression in thick ascending limb cells.
Hypertension (Dallas, Tex. : 1979) Jun, 2007 | Pubmed ID: 17438304
Inhibition of cytokine production and cytotoxic activity of human antimelanoma specific CD8+ and CD4+ T lymphocytes by adenosine-protein kinase A type I signaling.
Cancer research Jun, 2007 | Pubmed ID: 17575165
Emergency preservation and resuscitation with profound hypothermia, oxygen, and glucose allows reliable neurological recovery after 3 h of cardiac arrest from rapid exsanguination in dogs.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism Feb, 2008 | Pubmed ID: 17622254
Increases in cerebrospinal fluid caffeine concentration are associated with favorable outcome after severe traumatic brain injury in humans.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism Feb, 2008 | Pubmed ID: 17684518
Inhibition of renal dipeptidyl peptidase IV enhances peptide YY1-36-induced potentiation of angiotensin II-mediated renal vasoconstriction in spontaneously hypertensive rats.
The Journal of pharmacology and experimental therapeutics Nov, 2007 | Pubmed ID: 17726157
Cellular distribution of the renal bumetanide-sensitive Na-K-2Cl cotransporter BSC-1 in the inner stripe of the outer medulla during the development of hypertension in the spontaneously hypertensive rat.
Clinical and experimental pharmacology & physiology Dec, 2007 | Pubmed ID: 17973873
Early renal injury induced by caffeine consumption in obese, diabetic ZSF1 rats.
Renal failure , 2007 | Pubmed ID: 17994459
Importance of tissue perfusion in ST segment elevation myocardial infarction patients undergoing reperfusion strategies: role of adenosine.
Clinical cardiology Nov, 2007 | Pubmed ID: 18000974
Multiplex assessment of cytokine and chemokine levels in cerebrospinal fluid following severe pediatric traumatic brain injury: effects of moderate hypothermia.
Journal of neurotrauma Nov, 2007 | Pubmed ID: 18001201
Effects of dipeptidyl peptidase iv inhibition on arterial blood pressure.
Clinical and experimental pharmacology & physiology Jan, 2008 | Pubmed ID: 18047624
Chronic noradrenaline increases renal expression of NHE-3, NBC-1, BSC-1 and aquaporin-2.
Clinical and experimental pharmacology & physiology May, 2008 | Pubmed ID: 18177483
Regulation of renal ectophosphodiesterase by protein kinase C and sodium diet.
The Journal of pharmacology and experimental therapeutics Apr, 2008 | Pubmed ID: 18223197
Alpha2-adrenoceptors enhance angiotensin II-induced renal vasoconstriction: role for NADPH oxidase and RhoA.
Hypertension (Dallas, Tex. : 1979) Mar, 2008 | Pubmed ID: 18250367
Assessment of nerve stimulation-induced release of purines from mouse kidneys by tandem mass spectrometry.
The Journal of pharmacology and experimental therapeutics Jun, 2008 | Pubmed ID: 18322147
2-Ethoxyestradiol is antimitogenic and attenuates monocrotaline-induced pulmonary hypertension and vascular remodeling.
Vascular pharmacology Apr-Jun, 2008 | Pubmed ID: 18373958
Sitagliptin augments sympathetic enhancement of the renovascular effects of angiotensin II in genetic hypertension.
Hypertension (Dallas, Tex. : 1979) Jun, 2008 | Pubmed ID: 18443229
Identification and quantification of 2',3'-cAMP release by the kidney.
The Journal of pharmacology and experimental therapeutics Mar, 2009 | Pubmed ID: 19033554
Treating acute "no-reflow" with intracoronary adenosine in 4 patients during percutaneous coronary intervention.
Texas Heart Institute journal , 2008 | Pubmed ID: 19156238
Nonresolving inflammation in gp91phox-/- mice, a model of human chronic granulomatous disease, has lower adenosine and cyclic adenosine 5'-monophosphate.
Journal of immunology (Baltimore, Md. : 1950) Mar, 2009 | Pubmed ID: 19234224
Adenosine deaminase-adenosine pathway in hemolysis-associated pulmonary hypertension.
Medical hypotheses Jun, 2009 | Pubmed ID: 19237250
Regulation of renovascular adenosine 3',5'-cyclic monophosphate in spontaneously hypertensive rats.
Hypertension (Dallas, Tex. : 1979) Aug, 2009 | Pubmed ID: 19528365
2-methoxyestradiol attenuates bleomycin-induced pulmonary hypertension and fibrosis in estrogen-deficient rats.
Vascular pharmacology Aug-Sep, 2009 | Pubmed ID: 19540933
Multidrug resistance protein 4 mediates cAMP efflux from rat preglomerular vascular smooth muscle cells.
Clinical and experimental pharmacology & physiology Feb, 2010 | Pubmed ID: 19671067
Potential vascular actions of 2-methoxyestradiol.
Trends in endocrinology and metabolism: TEM Oct, 2009 | Pubmed ID: 19734053
Effects of estradiol metabolites on cAMP production and degradation.
Prilozi Jul, 2009 | Pubmed ID: 19736528
Extracellular 2',3'-cAMP is a source of adenosine.
The Journal of biological chemistry Nov, 2009 | Pubmed ID: 19801686
Increased ectonucleotidase expression and activity in regulatory T cells of patients with head and neck cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research Oct, 2009 | Pubmed ID: 19825957
Generation and accumulation of immunosuppressive adenosine by human CD4+CD25highFOXP3+ regulatory T cells.
The Journal of biological chemistry Mar, 2010 | Pubmed ID: 19858205
Adenosine A1 receptor activation as a brake on the microglial response after experimental traumatic brain injury in mice.
Journal of neurotrauma May, 2010 | Pubmed ID: 20121416
Extracellular 3',5'-cAMP-adenosine pathway inhibits glomerular mesangial cell growth.
The Journal of pharmacology and experimental therapeutics Jun, 2010 | Pubmed ID: 20194527
Sitagliptin augments angiotensin II-induced renal vasoconstriction in kidneys from rats with metabolic syndrome.
Clinical and experimental pharmacology & physiology Jul, 2010 | Pubmed ID: 20374254
Extracellular 2,3-cyclic adenosine monophosphate is a potent inhibitor of preglomerular vascular smooth muscle cell and mesangial cell growth [corrected].
Hypertension (Dallas, Tex. : 1979) Jul, 2010 | Pubmed ID: 20516392
Resveratrol, a red wine constituent, blocks the antimitogenic effects of estradiol on human female coronary artery smooth muscle cells.
The Journal of clinical endocrinology and metabolism Sep, 2010 | Pubmed ID: 20534756
Adenosine and prostaglandin E2 cooperate in the suppression of immune responses mediated by adaptive regulatory T cells.
The Journal of biological chemistry Sep, 2010 | Pubmed ID: 20558731
Estradiol stimulates capillary formation by human endothelial progenitor cells: role of estrogen receptor-{alpha}/{beta}, heme oxygenase 1, and tyrosine kinase.
Hypertension Sep, 2010 | Pubmed ID: 20644008
Synergistic therapeutic effects of 2-methoxyestradiol with either sildenafil or bosentan on amelioration of monocrotaline-induced pulmonary hypertension and vascular remodeling.
Journal of cardiovascular pharmacology Nov, 2010 | Pubmed ID: 20881615
Candidate genes and mechanisms for 2-methoxyestradiol-mediated vasoprotection.
Hypertension (Dallas, Tex. : 1979) Nov, 2010 | Pubmed ID: 20921434
Receptor desensitization and blockade of the suppressive effects of prostaglandin E(2) and adenosine on the cytotoxic activity of human melanoma-infiltrating T lymphocytes.
Cancer immunology, immunotherapy : CII Jan, 2011 | Pubmed ID: 20960188
Regulation of 3',5'-cAMP in preglomerular smooth muscle and endothelial cells from genetically hypertensive rats.
Hypertension (Dallas, Tex. : 1979) Dec, 2010 | Pubmed ID: 20975032
2'-AMP and 3'-AMP inhibit proliferation of preglomerular vascular smooth muscle cells and glomerular mesangial cells via A2B receptors.
The Journal of pharmacology and experimental therapeutics May, 2011 | Pubmed ID: 21270135
Blast exposure in rats with body shielding is characterized primarily by diffuse axonal injury.
Journal of neurotrauma Jun, 2011 | Pubmed ID: 21449683
Role of sphingosine-1-phosphate in the renal medulla.
American journal of physiology. Renal physiology Jul, 2011 | Pubmed ID: 21511695
2',3'-cAMP, 3'-AMP, and 2'-AMP inhibit human aortic and coronary vascular smooth muscle cell proliferation via A2B receptors.
American journal of physiology. Heart and circulatory physiology Aug, 2011 | Pubmed ID: 21622827
Extracellular cAMP-adenosine pathways in the mouse kidney.
American journal of physiology. Renal physiology Sep, 2011 | Pubmed ID: 21653635
Expression of the 2',3'-cAMP-adenosine pathway in astrocytes and microglia.
Journal of neurochemistry Sep, 2011 | Pubmed ID: 21777245
Receptor for activated protein kinase C1 regulates cell proliferation by modulating calcium signaling.
Hypertension Oct, 2011 | Pubmed ID: 21844488
The 2',3'-cAMP-adenosine pathway.
American journal of physiology. Renal physiology Dec, 2011 | Pubmed ID: 21937608
Microglial depletion using intrahippocampal injection of liposome-encapsulated clodronate in prolonged hypothermic cardiac arrest in rats.
Resuscitation Apr, 2012 | Pubmed ID: 21970817
Endogenous adenosine contributes to renal sympathetic neurotransmission via postjunctional A1 receptor-mediated coincident signaling.
American journal of physiology. Renal physiology Feb, 2012 | Pubmed ID: 22114202
Hypertension, tachycardia, and reversible cardiomyopathy temporally associated with milnacipran use.
Texas Heart Institute journal , 2011 | Pubmed ID: 22199446
Increased adenosine concentration in bronchoalveolar lavage fluid of horses with lower airway inflammation.
Veterinary journal (London, England : 1997) Dec, 2011 | Pubmed ID: 22206730
The brain in vivo expresses the 2',3'-cAMP-adenosine pathway.
Journal of neurochemistry Jul, 2012 | Pubmed ID: 22360621
Modulation of bladder function by luminal adenosine turnover and A1 receptor activation.
American journal of physiology. Renal physiology Jul, 2012 | Pubmed ID: 22552934
Extracellular 2',3'-cAMP and 3',5'-cAMP stimulate proliferation of preglomerular vascular endothelial cells and renal epithelial cells.
American journal of physiology. Renal physiology Oct, 2012 | Pubmed ID: 22791337
Dipeptidyl peptidase IV regulates proliferation of preglomerular vascular smooth muscle and mesangial cells.
Hypertension (Dallas, Tex. : 1979) Sep, 2012 | Pubmed ID: 22802229
Role of A1 receptors in renal sympathetic neurotransmission in the mouse kidney.
American journal of physiology. Renal physiology Oct, 2012 | Pubmed ID: 22874760
CD26 expression and adenosine deaminase activity in regulatory T cells (Treg) and CD4(+) T effector cells in patients with head and neck squamous cell carcinoma.
Oncoimmunology Aug, 2012 | Pubmed ID: 22934258
Extracellular 2',3'-cAMP-adenosine pathway in proximal tubular, thick ascending limb, and collecting duct epithelial cells.
American journal of physiology. Renal physiology Jan, 2013 | Pubmed ID: 23077101
Extracellular guanosine regulates extracellular adenosine levels.
American journal of physiology. Cell physiology Mar, 2013 | Pubmed ID: 23242185
Role of RACK1 in the differential proliferative effects of neuropeptide Y(1-36) and peptide YY(1-36) in SHR vs. WKY preglomerular vascular smooth muscle cells.
American journal of physiology. Renal physiology Mar, 2013 | Pubmed ID: 23303411
Screening of biochemical and molecular mechanisms of secondary injury and repair in the brain after experimental blast-induced traumatic brain injury in rats.
Journal of neurotrauma Jun, 2013 | Pubmed ID: 23496248
Adenosine production by human B cells and B cell-mediated suppression of activated T cells.
Blood Jul, 2013 | Pubmed ID: 23678003
In vivo cardiovascular pharmacology of 2',3'-cAMP, 2'-AMP, and 3'-AMP in the rat.
The Journal of pharmacology and experimental therapeutics Aug, 2013 | Pubmed ID: 23759508
CD39 expression by hepatic myeloid dendritic cells attenuates inflammation in liver transplant ischemia-reperfusion injury in mice.
Hepatology (Baltimore, Md.) Dec, 2013 | Pubmed ID: 23813862
Adenosine and prostaglandin e2 production by human inducible regulatory T cells in health and disease.
Frontiers in immunology , 2013 | Pubmed ID: 23898333
Role of CNPase in the oligodendrocytic extracellular 2',3'-cAMP-adenosine pathway.
Glia Oct, 2013 | Pubmed ID: 23922219
Regulation of Cell Proliferation by the Guanosine-Adenosine Mechanism: Role of Adenosine Receptors.
Physiological reports Aug, 2013 | Pubmed ID: 23956837
The β-blocker Nebivolol Is a GRK/β-arrestin biased agonist.
PloS one , 2013 | Pubmed ID: 23977191
CD4⁺CD73⁺ T cells are associated with lower T-cell activation and C reactive protein levels and are depleted in HIV-1 infection regardless of viral suppression.
AIDS (London, England) Jun, 2013 | Pubmed ID: 24005375
Pharmacological inhibition of pleckstrin homology domain leucine-rich repeat protein phosphatase is neuroprotective: differential effects on astrocytes.
The Journal of pharmacology and experimental therapeutics Nov, 2013 | Pubmed ID: 24023368
Role of CD73 in Renal Sympathetic Neurotransmission in the Mouse Kidney.
Physiological reports Aug, 2013 | Pubmed ID: 24066228
A novel adenosine precursor 2',3'-cyclic adenosine monophosphate inhibits formation of post-surgical adhesions.
Digestive diseases and sciences Sep, 2014 | Pubmed ID: 24711075
Hemorrhagic shock shifts the serum cytokine profile from pro- to anti-inflammatory after experimental traumatic brain injury in mice.
Journal of neurotrauma Aug, 2014 | Pubmed ID: 24773520
Role of 2',3'-cyclic nucleotide 3'-phosphodiesterase in the renal 2',3'-cAMP-adenosine pathway.
American journal of physiology. Renal physiology Jul, 2014 | Pubmed ID: 24808540
Guanosine regulates adenosine levels in the kidney.
Physiological reports May, 2014 | Pubmed ID: 24872359
Interactive roles of CD73 and tissue nonspecific alkaline phosphatase in the renal vascular metabolism of 5'-AMP.
American journal of physiology. Renal physiology Sep, 2014 | Pubmed ID: 24990899
The guanosine-adenosine interaction exists in vivo.
The Journal of pharmacology and experimental therapeutics Sep, 2014 | Pubmed ID: 25002416
Angiotensin II type 2 receptor regulates ROMK-like K⁺ channel activity in the renal cortical collecting duct during high dietary K⁺ adaptation.
American journal of physiology. Renal physiology Oct, 2014 | Pubmed ID: 25100281
Systemic oxygenation weakens the hypoxia and hypoxia inducible factor 1α-dependent and extracellular adenosine-mediated tumor protection.
Journal of molecular medicine (Berlin, Germany) Dec, 2014 | Pubmed ID: 25120128
Prevention of skin carcinogenesis by the β-blocker carvedilol.
Cancer prevention research (Philadelphia, Pa.) Jan, 2015 | Pubmed ID: 25367979
Effect of dipeptidyl peptidase 4 inhibition on arterial blood pressure is context dependent.
Hypertension (Dallas, Tex. : 1979) Jan, 2015 | Pubmed ID: 25368027
2',3'-cAMP, 3'-AMP, 2'-AMP and adenosine inhibit TNF-α and CXCL10 production from activated primary murine microglia via A2A receptors.
Brain research Jan, 2015 | Pubmed ID: 25451117
Blockade of ENaCs by amiloride induces c-Fos activation of the area postrema.
Brain research Mar, 2015 | Pubmed ID: 25557402
The nuclear splicing factor RNA binding motif 5 promotes caspase activation in human neuronal cells, and increases after traumatic brain injury in mice.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism Apr, 2015 | Pubmed ID: 25586139
Emerging therapies in traumatic brain injury.
Seminars in neurology Feb, 2015 | Pubmed ID: 25714870
Immunological mechanisms of the antitumor effects of supplemental oxygenation.
Science translational medicine Mar, 2015 | Pubmed ID: 25739764
Detection of PHLPP1α/β in human and mouse brain by different anti-PHLPP1 antibodies.
Scientific reports Apr, 2015 | Pubmed ID: 25827478
Schwann Cells Metabolize Extracellular 2',3'-cAMP to 2'-AMP.
The Journal of pharmacology and experimental therapeutics Aug, 2015 | Pubmed ID: 25998049
Structure Guided Chemical Modifications of Propylthiouracil Reveal Novel Small Molecule Inhibitors of Cytochrome b5 Reductase 3 That Increase Nitric Oxide Bioavailability.
The Journal of biological chemistry Jul, 2015 | Pubmed ID: 26001785
Genetic variation in the adenosine regulatory cycle is associated with posttraumatic epilepsy development.
Epilepsia Aug, 2015 | Pubmed ID: 26040919
Critical Role for the Adenosine Pathway in Controlling Simian Immunodeficiency Virus-Related Immune Activation and Inflammation in Gut Mucosal Tissues.
Journal of virology Sep, 2015 | Pubmed ID: 26178986
Cold stress protein RBM3 responds to temperature change in an ultra-sensitive manner in young neurons.
Neuroscience Oct, 2015 | Pubmed ID: 26265550
NPY1-36 and PYY1-36 activate cardiac fibroblasts: an effect enhanced by genetic hypertension and inhibition of dipeptidyl peptidase 4.
American journal of physiology. Heart and circulatory physiology Nov, 2015 | Pubmed ID: 26371160
Adenosine Attenuates Human Coronary Artery Smooth Muscle Cell Proliferation by Inhibiting Multiple Signaling Pathways That Converge on Cyclin D.
Hypertension (Dallas, Tex. : 1979) Dec, 2015 | Pubmed ID: 26416848
2-Methoxyestradiol blocks the RhoA/ROCK1 pathway in human aortic smooth muscle cells.
American journal of physiology. Endocrinology and metabolism Dec, 2015 | Pubmed ID: 26487003
Renal 2',3'-Cyclic Nucleotide 3'-Phosphodiesterase Is an Important Determinant of AKI Severity after Ischemia-Reperfusion.
Journal of the American Society of Nephrology : JASN 07, 2016 | Pubmed ID: 26574047
Dual A1/A2B Receptor Blockade Improves Cardiac and Renal Outcomes in a Rat Model of Heart Failure with Preserved Ejection Fraction.
The Journal of pharmacology and experimental therapeutics Feb, 2016 | Pubmed ID: 26585572
Discovery and Roles of 2',3'-cAMP in Biological Systems.
Handbook of experimental pharmacology , 2017 | Pubmed ID: 26721674
2-Methoxyestradiol, an endogenous 17β-estradiol metabolite, inhibits microglial proliferation and activation via an estrogen receptor-independent mechanism.
American journal of physiology. Endocrinology and metabolism Mar, 2016 | Pubmed ID: 26732685
Purines: forgotten mediators in traumatic brain injury.
Journal of neurochemistry Apr, 2016 | Pubmed ID: 26809224
Adenosine metabolism of human mesenchymal stromal cells isolated from patients with head and neck squamous cell carcinoma.
Immunobiology 01, 2017 | Pubmed ID: 26898925
Estrogens in Men: Another Layer of Complexity of Estradiol Metabolism in Pulmonary Hypertension.
American journal of respiratory and critical care medicine 05, 2016 | Pubmed ID: 27174480
8-Aminoguanosine and 8-Aminoguanine Exert Diuretic, Natriuretic, Glucosuric, and Antihypertensive Activity.
The Journal of pharmacology and experimental therapeutics Dec, 2016 | Pubmed ID: 27679494
The Kallikrein-Kinin System: A Novel Mediator of IL-17-Driven Anti-Candida Immunity in the Kidney.
PLoS pathogens Nov, 2016 | Pubmed ID: 27814401
Context-dependent effects of dipeptidyl peptidase 4 inhibitors.
Current opinion in nephrology and hypertension 03, 2017 | Pubmed ID: 27898522
RACK1 regulates angiotensin II-induced contractions of SHR preglomerular vascular smooth muscle cells.
American journal of physiology. Renal physiology 04, 2017 | Pubmed ID: 28100502
Alkaline Phosphatase Inhibitors Attenuate Renovascular Responses to Norepinephrine.
Hypertension (Dallas, Tex. : 1979) 03, 2017 | Pubmed ID: 28137984
Editorial for "Hypertension's 3 Dilemmas & 3 Solutions: Pharmacology of the Kidney in Hypertension".
Journal of cardiovascular pharmacology 03, 2017 | Pubmed ID: 28267686
Adenosine production by brain cells.
Journal of neurochemistry 06, 2017 | Pubmed ID: 28294336
Suppression of Lymphocyte Functions by Plasma Exosomes Correlates with Disease Activity in Patients with Head and Neck Cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research Aug, 2017 | Pubmed ID: 28400428
Proximal tubule apical endocytosis is modulated by fluid shear stress via an mTOR-dependent pathway.
Molecular biology of the cell Sep, 2017 | Pubmed ID: 28720662
Human tumor-derived exosomes (TEX) regulate Treg functions via cell surface signaling rather than uptake mechanisms.
Oncoimmunology , 2017 | Pubmed ID: 28919985
8-Aminoguanosine Exerts Diuretic, Natriuretic, and Glucosuric Activity via Conversion to 8-Aminoguanine, Yet Has Direct Antikaliuretic Effects.
The Journal of pharmacology and experimental therapeutics 12, 2017 | Pubmed ID: 28928119
Circulating exosomes carrying an immunosuppressive cargo interfere with cellular immunotherapy in acute myeloid leukemia.
Scientific reports 10, 2017 | Pubmed ID: 29089618
SDF-1α (Stromal Cell-Derived Factor 1α) Induces Cardiac Fibroblasts, Renal Microvascular Smooth Muscle Cells, and Glomerular Mesangial Cells to Proliferate, Cause Hypertrophy, and Produce Collagen.
Journal of the American Heart Association Nov, 2017 | Pubmed ID: 29114002
BrainPhys® increases neurofilament levels in CNS cultures, and facilitates investigation of axonal damage after a mechanical stretch-injury in vitro.
Experimental neurology 02, 2018 | Pubmed ID: 29199132
The influence of chemotherapy on adenosine-producing B cells in patients with head and neck squamous cell carcinoma.
Oncotarget Jan, 2018 | Pubmed ID: 29464038
Captopril Attenuates Cardiovascular and Renal Disease in a Rat Model of Heart Failure With Preserved Ejection Fraction.
Journal of cardiovascular pharmacology 04, 2018 | Pubmed ID: 29620605
Acute Physiology and Neurologic Outcomes after Brain Injury in SCOP/PHLPP1 KO Mice.
Scientific reports 05, 2018 | Pubmed ID: 29739983
Adenosine Receptors Influence Hypertension in Dahl Salt-Sensitive Rats: Dependence on Receptor Subtype, Salt Diet, and Sex.
Hypertension (Dallas, Tex. : 1979) 08, 2018 | Pubmed ID: 29941515
Experimental intravascular hemolysis induces hemodynamic and pathological pulmonary hypertension: association with accelerated purine metabolism.
Pulmonary circulation Jul-Sep, 2018 | Pubmed ID: 30003836
Aging increases the expression of vasopressin receptors in both the kidney and urinary bladder.
Neurourology and urodynamics 01, 2019 | Pubmed ID: 30311671
Extracellular Ubiquitin(1-76) and Ubiquitin(1-74) Regulate Cardiac Fibroblast Proliferation.
Hypertension (Dallas, Tex. : 1979) 10, 2018 | Pubmed ID: 30354710
Oxidative stress induces release of 2'-AMP from microglia.
Brain research 03, 2019 | Pubmed ID: 30395838
Paths to Successful Translation of New Therapies for Severe Traumatic Brain Injury in the Golden Age of Traumatic Brain Injury Research: A Pittsburgh Vision.
Journal of neurotrauma 11, 2020 | Pubmed ID: 30520681
8-Aminoguanine Induces Diuresis, Natriuresis, and Glucosuria by Inhibiting Purine Nucleoside Phosphorylase and Reduces Potassium Excretion by Inhibiting Rac1.
Journal of the American Heart Association 11, 2018 | Pubmed ID: 30608204
2',3'-cGMP exists in vivo and comprises a 2',3'-cGMP-guanosine pathway.
American journal of physiology. Regulatory, integrative and comparative physiology 06, 2019 | Pubmed ID: 30789788
2-Methoxyestradiol Attenuates Angiotensin II-Induced Hypertension, Cardiovascular Remodeling, and Renal Injury.
Journal of cardiovascular pharmacology 03, 2019 | Pubmed ID: 30839510
Mechanism of 17β-estradiol stimulated integration of human mesenchymal stem cells in heart tissue.
Journal of molecular and cellular cardiology 08, 2019 | Pubmed ID: 31201797
A Randomized, Placebo-Controlled, Pilot Clinical Trial of Dipyridamole to Decrease Human Immunodeficiency Virus-Associated Chronic Inflammation.
The Journal of infectious diseases 04, 2020 | Pubmed ID: 31282542
Adenosine, Via A Receptors, Inhibits Human (P-SMC) Progenitor Smooth Muscle Cell Growth.
Hypertension (Dallas, Tex. : 1979) 01, 2020 | Pubmed ID: 31786976
Estradiol Metabolism: Crossroads in Pulmonary Arterial Hypertension.
International journal of molecular sciences Dec, 2019 | Pubmed ID: 31877978
DPP4 Inhibition, NPY, PYY, SDF-1, and a Hypertensive Genetic Background Conspire to Augment Cell Proliferation and Collagen Production: Effects That Are Abolished by Low Concentrations of 2-Methoxyestradiol.
The Journal of pharmacology and experimental therapeutics 04, 2020 | Pubmed ID: 32015161
Adenosine-producing regulatory B cells in head and neck cancer.
Cancer immunology, immunotherapy : CII Jul, 2020 | Pubmed ID: 32146518
Activation of AMP-activated protein kinase during sepsis/inflammation improves survival by preserving cellular metabolic fitness.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 05, 2020 | Pubmed ID: 32246808
Intercalated cell BKα subunit is required for flow-induced K+ secretion.
JCI insight 04, 2020 | Pubmed ID: 32255763
Simultaneous Inhibition of Glycolysis and Oxidative Phosphorylation Triggers a Multi-Fold Increase in Secretion of Exosomes: Possible Role of 2'3'-cAMP.
Scientific reports 04, 2020 | Pubmed ID: 32332778
Identification of Novel Targets of RBM5 in the Healthy and Injured Brain.
Neuroscience 08, 2020 | Pubmed ID: 32335213
Characterization of the N-etheno-bridge method to assess extracellular metabolism of adenine nucleotides: detection of a possible role for purine nucleoside phosphorylase in adenosine metabolism.
Purinergic signalling 06, 2020 | Pubmed ID: 32367441
Tumor-derived exosomes promote angiogenesis via adenosine A receptor signaling.
Angiogenesis 11, 2020 | Pubmed ID: 32419057
-Adrenoceptors: Challenges and Opportunities-Enlightenment from the Kidney.
Cardiovascular therapeutics , 2020 | Pubmed ID: 32426035
Adenosine receptors regulate exosome production.
Purinergic signalling 06, 2020 | Pubmed ID: 32440820
Role of exosome-associated adenosine in promoting angiogenesis.
Vessel plus , 2020 | Pubmed ID: 32490359
Purine Metabolites in Tumor-Derived Exosomes May Facilitate Immune Escape of Head and Neck Squamous Cell Carcinoma.
Cancers Jun, 2020 | Pubmed ID: 32560461
Immune Suppressive Effects of Plasma-Derived Exosome Populations in Head and Neck Cancer.
Cancers Jul, 2020 | Pubmed ID: 32708274
Author Correction: Simultaneous Inhibition of Glycolysis and Oxidative Phosphorylation Triggers a Multi-Fold Increase in Secretion of Exosomes: Possible Role of 2',3'-cAMP.
Scientific reports Aug, 2020 | Pubmed ID: 32807847
Alkaline Phosphatase Activity Is a Key Determinant of Vascular Responsiveness to Norepinephrine.
Hypertension (Dallas, Tex. : 1979) 10, 2020 | Pubmed ID: 32829665
Purine nucleoside phosphorylase inhibition ameliorates age-associated lower urinary tract dysfunctions.
JCI insight 10, 2020 | Pubmed ID: 32910805
A uro-protective agent with restorative actions on urethral and striated muscle morphology.
World journal of urology Oct, 2020 | Pubmed ID: 33078215
Brief Report: Dipyridamole Decreases Gut Mucosal Regulatory T-Cell Frequencies Among People With HIV on Antiretroviral Therapy.
Journal of acquired immune deficiency syndromes (1999) 12, 2020 | Pubmed ID: 33177477
Novel Guidewire Design and Coating for Continuous Delivery of Adenosine During Interventional Procedures.
Journal of the American Heart Association Feb, 2021 | Pubmed ID: 33496190
Long-Term Dipeptidyl Peptidase 4 Inhibition Worsens Hypertension and Renal and Cardiac Abnormalities in Obese Spontaneously Hypertensive Heart Failure Rats.
Journal of the American Heart Association Mar, 2021 | Pubmed ID: 33682436
Angiotensin II augments renal vascular smooth muscle soluble GC expression via an AT receptor-forkhead box subclass O transcription factor signalling axis.
British journal of pharmacology May, 2021 | Pubmed ID: 33963547
Modulation of Cyclic AMP Levels in Fallopian Tube Cells by Natural and Environmental Estrogens.
Cells May, 2021 | Pubmed ID: 34069403
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