Chris I. Jones

A novel variant on chromosome 7q22.3 associated with mean platelet volume, counts, and function.

PECAM-1 expression and activity negatively regulate multiple platelet signaling pathways.

Platelets release novel thiol isomerase enzymes which are recruited to the cell surface following activation.

LXR as a novel antithrombotic target.

Regulation of platelet biology by platelet endothelial cell adhesion molecule-1.

Endogenous inhibitory mechanisms and the regulation of platelet function.

Gap junctions and connexin hemichannels underpin hemostasis and thrombosis.

Tangeretin regulates platelet function through inhibition of phosphoinositide 3-kinase and cyclic nucleotide signaling.

Platelet endothelial cell adhesion molecule-1 inhibits platelet response to thrombin and von Willebrand factor by regulating the internalization of glycoprotein Ib via AKT/glycogen synthase kinase-3/dynamin and integrin αIIbβ3.

Discovery of novel GPVI receptor antagonists by structure-based repurposing.

EphB2 regulates contact-dependent and contact-independent signaling to control platelet function.

Pharmacological actions of nobiletin in the modulation of platelet function.

Syncytiotrophoblast Extracellular Vesicles from Pre-Eclampsia Placentas Differentially Affect Platelet Function.

Platelet function and ageing.

Evidence for shear-mediated Ca entry through mechanosensitive cation channels in human platelets and a megakaryocytic cell line.

Farnesoid X Receptor and Liver X Receptor Ligands Initiate Formation of Coated Platelets.

Immobilization of Nonactivated Unfixed Platelets for Real-Time Single-Cell Analysis.

Structural, functional, and mechanistic insights uncover the fundamental role of orphan connexin-62 in platelets.

An efficient alpha helix model and simulation framework for stationary electrostatic interaction force estimation.

Multi-parameter phenotyping of platelet reactivity for stratification of human cohorts.