Manabu Tokeshi

Division of Applied Chemistry, Hokkaido University

Research Area

Biochemistry

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2022

Other Publications

Article	Year
Fabrication of functionalized double-lamellar multifunctional envelope-type nanodevices using a microfluidic chip with a chaotic mixer array. PloS one\| PubMed ID: 22723929	2012
A method of cryoprotection for protein crystallography by using a microfluidic chip and its application for in situ X-ray diffraction measurements. Analytical chemistry\| PubMed ID: 25834918	2015
Arrangement of a nanostructure array to control equilibrium and nonequilibrium transports of macromolecules. Nano letters\| PubMed ID: 25879141	2015
A microfluidic cell culture system for monitoring of sequential changes in endothelial cells after heat stress. Thrombosis research\| PubMed ID: 26044666	2015
An instrument-free, screen-printed paper microfluidic device that enables bio and chemical sensing. The Analyst\| PubMed ID: 26207925	2015
Fluorescence polarization measurement system using a liquid crystal layer and an image sensor. Analytical chemistry\| PubMed ID: 26352939	2015
A Portable Liquid Chromatograph with a Battery-operated Compact Electroosmotic Pump and a Microfluidic Chip Device with a Reversed Phase Packed Column. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry\| PubMed ID: 26561261	2015
Microfluidic Approaches for Protein Crystal Structure Analysis. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry\| PubMed ID: 26753699	2016
Elucidation of the physicochemical properties and potency of siRNA-loaded small-sized lipid nanoparticles for siRNA delivery. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 26995758	2016
3,3',5,5'-Tetramethylbenzidine Oxidation on Paper Devices for Horseradish Peroxidase-based Assays. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry\| PubMed ID: 27506705	2016
Label-free detection of real-time DNA amplification using a nanofluidic diffraction grating. Scientific reports\| PubMed ID: 27531471	2016
Novel concept of washing for microfluidic paper-based analytical devices based on capillary force of paper substrates. Analytical and bioanalytical chemistry\| PubMed ID: 27544520	2016
Image analysis for a microfluidic paper-based analytical device using the CIE Lab* color system. The Analyst\| PubMed ID: 27830841	2016
A competitive immunoassay system for microfluidic paper-based analytical detection of small size molecules. The Analyst\| PubMed ID: 27858015	2016
An immuno-wall microdevice exhibits rapid and sensitive detection of IDH1-R132H mutation specific to grade II and III gliomas. Science and technology of advanced materials\| PubMed ID: 27877908	2016
Rapid Detection of Cat Cystatin C (cCys-C) Using Immuno-Pillar Chips. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry\| PubMed ID: 27941268	2016
Fabrication and Evaluation of Microfluidic Immunoassay Devices with Antibody-Immobilized Microbeads Retained in Porous Hydrogel Micropillars. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 28044286	2017
A millisecond micro-RNA separation technique by a hybrid structure of nanopillars and nanoslits. Scientific reports\| PubMed ID: 28272420	2017
Using Laser Interference Lithography in the Fabrication of a Simplified Micro- and Nanofluidic Device for Label-free Detection. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry\| PubMed ID: 28993597	2017
Understanding the formation mechanism of lipid nanoparticles in microfluidic devices with chaotic micromixers. PloS one\| PubMed ID: 29182626	2017
Characteristics of Microfluidic Paper-based Analytical Devices Fabricated by Four Different Methods. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry\| PubMed ID: 29321455	2018
A compact fluorescence polarization analyzer with high-transmittance liquid crystal layer. The Review of scientific instruments\| PubMed ID: 29495833	2018
Advances in microfluidics for lipid nanoparticles and extracellular vesicles and applications in drug delivery systems. Advanced drug delivery reviews\| PubMed ID: 29567396	2018
Microfluidic Devices for Drug Delivery Systems. Advanced drug delivery reviews\| PubMed ID: 29908612	2018
Advances in Microfluidic Paper-Based Analytical Devices for Food and Water Analysis. Micromachines\| PubMed ID: 30404261	2016
Microfluidic Autologous Serum Eye-Drops Preparation as a Potential Dry Eye Treatment. Micromachines\| PubMed ID: 30404287	2016
Micro/Nano Devices for Chemical Analysis. Micromachines\| PubMed ID: 30404336	2016
Recent Microdevice-Based Aptamer Sensors. Micromachines\| PubMed ID: 30424135	2018
Development of a microdevice for facile analysis of theophylline in whole blood by a cloned enzyme donor immunoassay. Lab on a chip\| PubMed ID: 30547178	2019
Understanding structure-activity relationships of pH-sensitive cationic lipids facilitates the rational identification of promising lipid nanoparticles for delivering siRNAs in vivo. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 30610950	2019
The Use of a Microfluidic Device to Encapsulate a Poorly Water-Soluble Drug CoQ in Lipid Nanoparticles and an Attempt to Regulate Intracellular Trafficking to Reach Mitochondria. Journal of pharmaceutical sciences\| PubMed ID: 30959057	2019
Ultrasensitive detection of disease biomarkers using an immuno-wall device with enzymatic amplification. The Analyst\| PubMed ID: 31237262	2019
High-throughput fluorescence polarization immunoassay by using a portable fluorescence polarization imaging analyzer. Lab on a chip\| PubMed ID: 31250849	2019
An Electrochemical Sensor Based on Structure Switching of Dithiol-modified Aptamer for Simple Detection of Ochratoxin A. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry\| PubMed ID: 31327816	2019
A paper-based analytical device coupled with electrochemical detection for the determination of dexamethasone and prednisolone in adulterated traditional medicines. Analytica chimica acta\| PubMed ID: 31358214	2019
Development of the iLiNP Device: Fine Tuning the Lipid Nanoparticle Size within 10 nm for Drug Delivery. ACS omega\| PubMed ID: 31458718	2018
Rapid, Sensitive, and Selective Detection of H5 Hemagglutinin from Avian Influenza Virus Using an Immunowall Device. ACS omega\| PubMed ID: 31616851	2019
Hydrophobic scaffolds of pH-sensitive cationic lipids contribute to miscibility with phospholipids and improve the efficiency of delivering short interfering RNA by small-sized lipid nanopar... Acta biomaterialia\| PubMed ID: 31733331	2020
The Effect of Size and Charge of Lipid Nanoparticles Prepared by Microfluidic Mixing on Their Lymph Node Transitivity and Distribution. Molecular pharmaceutics\| PubMed ID: 31990567	2020
Paper-Based Device for the Facile Colorimetric Determination of Lithium Ions in Human Whole Blood. ACS sensors\| PubMed ID: 32283919	2020
Rapid detection of anti-H5 avian influenza virus antibody by fluorescence polarization immunoassay using a portable fluorescence polarization analyzer. Sensors and actuators. B, Chemical\| PubMed ID: 32322135	2020
Observation of Ethanol-Induced Condensation and Decondensation Processes at a Single-DNA Molecular Level in Microfluidic Devices Equipped with a Rapid Solution Exchange System. Analytical chemistry\| PubMed ID: 32483963	2020
Development of a Microfluidic-Based Post-Treatment Process for Size-Controlled Lipid Nanoparticles and Application to siRNA Delivery. ACS applied materials & interfaces\| PubMed ID: 32667806	2020
Real-Time Measurement of Protein Crystal Growth Rates within the Microfluidic Device to Understand the Microspace Effect. ACS omega\| PubMed ID: 32715205	2020
The use of design of experiments with multiple responses to determine optimal formulations for in vivo hepatic mRNA delivery. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 32853732	2020
Noncompetitive Fluorescence Polarization Immunoassay for Protein Determination. Analytical chemistry\| PubMed ID: 33094615	2020
Development of an immuno-wall device for the rapid and sensitive detection of EGFR mutations in tumor tissues resected from lung cancer patients. PloS one\| PubMed ID: 33196648	2020
Enhanced dispersion stability of gold nanoparticles by the physisorption of cyclic poly(ethylene glycol). Nature communications\| PubMed ID: 33257670	2020
Lipid nanoparticles loaded with ribonucleoprotein-oligonucleotide complexes synthesized using a microfluidic device exhibit robust genome editing and hepatitis B virus inhibition. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 33333121	2021
Rapid, sensitive universal paper-based device enhances competitive immunoassays of small molecules. Analytica chimica acta\| PubMed ID: 33453801	2021
Non-competitive fluorescence polarization immunoassay for detection of H5 avian influenza virus using a portable analyzer. Analytical and bioanalytical chemistry\| PubMed ID: 33547481	2021
Dip-Type Paper-Based Analytical Device for Straightforward Quantitative Detection without Precise Sample Introduction. ACS sensors\| PubMed ID: 33660502	2021
Simple Approach for Fluorescence Signal Amplification Utilizing a Poly(vinyl alcohol)-Based Polymer Structure in a Microchannel. ACS omega\| PubMed ID: 33817494	2021
Delivery of Oligonucleotides Using a Self-Degradable Lipid-Like Material. Pharmaceutics\| PubMed ID: 33924589	2021
Room-temperature crystallography using a microfluidic protein crystal array device and its application to protein-ligand complex structure analysis. Chemical science\| PubMed ID: 34094189	2020
Facile and rapid detection of SARS-CoV-2 antibody based on a noncompetitive fluorescence polarization immunoassay in human serum samples. Biosensors & bioelectronics\| PubMed ID: 34130087	2021
Determination of blood lithium-ion concentration using digital microfluidic whole-blood separation and preloaded paper sensors. Biosensors & bioelectronics\| PubMed ID: 34571482	2022
Microchip Immunoassays for Monitoring Renal Function: Rapid, Low-Cost, and Highly Sensitive Quantification of Urinary Biomarkers of Diabetic Nephropathy. Micromachines\| PubMed ID: 34832765	2021
Electrochemical enzyme-based blood ATP and lactate sensor for a rapid and straightforward evaluation of illness severity. Biosensors & bioelectronics\| PubMed ID: 34856516	2022
Topology-Dependent Interaction of Cyclic Poly(ethylene glycol) Complexed with Gold Nanoparticles against Bovine Serum Albumin for a Colorimetric Change. Langmuir : the ACS journal of surfaces and colloids\| PubMed ID: 34878285	2021
Paper-Based Analytical Device for the On-Site Detection of Nerve Agents. ACS applied bio materials\| PubMed ID: 35006863	2021
One-Step Production Using a Microfluidic Device of Highly Biocompatible Size-Controlled Noncationic Exosome-like Nanoparticles for RNA Delivery. ACS applied bio materials\| PubMed ID: 35014524	2021
Microfluidic technologies and devices for lipid nanoparticle-based RNA delivery. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 35183654	2022
Enzyme kinetics in confined geometries at the single enzyme level. The Analyst\| PubMed ID: 35230361	2022
Dimethoxytriadinylation LC-MS/MS of Novichok A-Series Degradation Products in Human Urine. Analytical chemistry\| PubMed ID: 35253439	2022