Anees Khatib is a Ph.D. student in the Biochemistry and Molecular Biology Department, The Hebrew University, Jerusalem. He received his first degree (B.Sc.) in Biotechnology from The Hadassah Academic College, Jerusalem.
In 2016, He started his M.Sc. degree at Yoav Shaul's lab, The Hebrew University. Anees developed an enthusiastic focus on a Mesenchymal Metabolic Signature (MMS) gene called Glutathione Peroxidase8 (gpx8), and on its essential role in maintaining Triple Negative Breast Cancer's aggressive phenotype.
In 2019, Anees completed his M.Sc. degree and started Ph.D. under the topic '' Characterization of GPX8 as a regulator of cancer cell fate''.
In 2020, He joined the Hebrew University teaching staff as a teaching assistant and received the prestigious Teva's Bio-Innovation Fellowship.
Anees is interested in cancer research and mainly in; Epithelial-Mesenchymal Transition (EMT), Tumor microenvironment (TME) and oncogenic signaling pathways.
Publications:
• Solaimuthu B, Hayashi A, Khatib A, Shaul YD. Monitoring Breast Cancer Growth and Metastatic Colony Formation in Mice using Bioluminescence. J Vis Exp. 2021. PMID: 34806708.
• Khatib A, Balakrishnan S, Ben Yosef M, Abu Rmaileh A, Tanna M, Oren G, Schlesinger Frisch M, Axelrod JH, Lichtenstein M, Shaul YD.The glutathione peroxidase 8 (GPX8)/IL-6/STAT3 axis is essential in maintaining an aggressive breast cancer phenotype. Proc Natl Acad Sci U S A (2020). 117:21420-21431. PMID: 32817494.
• Rmaileh AA, Balakrishnan S, Tanna M, Khatib A, Yosef MB, Hayashi A, Lichtenstein M, Shaul YD. Large-Scale Differential Gene Expression Transcriptomic Analysis Identifies a Metabolic Signature Shared by All Cancer Cells. Biomolecules (2020). 10:701. PMID: 32365991
