Mitchell Cancer Institute,
College of Medicine,
Mitchell Cancer Institute, College of Medicine
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CXCL8 and its cognate receptors in melanoma progression and metastasis.
Future oncology (London, England) Jan, 2010 | Pubmed ID: 20021212
MicroRNA-based Cancer Therapeutics: Big Hope from Small RNAs.
Molecular and cellular pharmacology , 2010 | Pubmed ID: 21289871
Modulation of protein phosphatase 2A activity alters androgen-independent growth of prostate cancer cells: therapeutic implications.
Molecular cancer therapeutics May, 2011 | Pubmed ID: 21393425
Honokiol arrests cell cycle, induces apoptosis, and potentiates the cytotoxic effect of gemcitabine in human pancreatic cancer cells.
PloS one , 2011 | Pubmed ID: 21720559
CXCR1 and CXCR2 silencing modulates CXCL8-dependent endothelial cell proliferation, migration and capillary-like structure formation.
Microvascular research Nov, 2011 | Pubmed ID: 21749879
MicroRNA-150 directly targets MUC4 and suppresses growth and malignant behavior of pancreatic cancer cells.
Carcinogenesis Dec, 2011 | Pubmed ID: 21983127
Myb overexpression overrides androgen depletion-induced cell cycle arrest and apoptosis in prostate cancer cells, and confers aggressive malignant traits: potential role in castration resistance.
Carcinogenesis Jun, 2012 | Pubmed ID: 22431717
Honokiol: a novel natural agent for cancer prevention and therapy.
Current molecular medicine Dec, 2012 | Pubmed ID: 22834827
CXCL12/CXCR4 protein signaling axis induces sonic hedgehog expression in pancreatic cancer cells via extracellular regulated kinase- and Akt kinase-mediated activation of nuclear factor κB: implications for bidirectional tumor-stromal interactions.
The Journal of biological chemistry Nov, 2012 | Pubmed ID: 22995914
An undesired effect of chemotherapy: gemcitabine promotes pancreatic cancer cell invasiveness through reactive oxygen species-dependent, nuclear factor κB- and hypoxia-inducible factor 1α-mediated up-regulation of CXCR4.
The Journal of biological chemistry Jul, 2013 | Pubmed ID: 23740244
Cancer "stemness"- regulating microRNAs: role, mechanisms and therapeutic potential.
Current drug targets Sep, 2013 | Pubmed ID: 23834145
MicroRNAs in pancreatic malignancy: progress and promises.
Cancer letters Jun, 2014 | Pubmed ID: 24561061
Synthesis, characterization, and evaluation of poly (D,L-lactide-co-glycolide)-based nanoformulation of miRNA-150: potential implications for pancreatic cancer therapy.
International journal of nanomedicine , 2014 | Pubmed ID: 24971005
p-21 activated kinase 4 promotes proliferation and survival of pancreatic cancer cells through AKT- and ERK-dependent activation of NF-κB pathway.
Oncotarget Sep, 2014 | Pubmed ID: 25238288
CXCL12/CXCR4 signaling counteracts docetaxel-induced microtubule stabilization via p21-activated kinase 4-dependent activation of LIM domain kinase 1.
Oncotarget Nov, 2014 | Pubmed ID: 25359780
Silver nanoparticles protect human keratinocytes against UVB radiation-induced DNA damage and apoptosis: potential for prevention of skin carcinogenesis.
Nanomedicine : nanotechnology, biology, and medicine Jul, 2015 | Pubmed ID: 25804413
Modulation of microRNAs by phytochemicals in cancer: underlying mechanisms and translational significance.
BioMed research international , 2015 | Pubmed ID: 25853141
MicroRNAs: emerging novel targets of cancer therapies.
BioMed research international , 2015 | Pubmed ID: 25866788
Resistin and interleukin-6 exhibit racially-disparate expression in breast cancer patients, display molecular association and promote growth and aggressiveness of tumor cells through STAT3 activation.
Oncotarget May, 2015 | Pubmed ID: 25868978
Gemcitabine triggers angiogenesis-promoting molecular signals in pancreatic cancer cells: Therapeutic implications.
Oncotarget Nov, 2015 | Pubmed ID: 25970774
MicroRNA-345 induces apoptosis in pancreatic cancer cells through potentiation of caspase-dependent and -independent pathways.
British journal of cancer Aug, 2015 | Pubmed ID: 26247574
Development and Characterization of a Novel in vitro Progression Model for UVB-Induced Skin Carcinogenesis.
Scientific reports Sep, 2015 | Pubmed ID: 26349906
Size is an essential parameter in governing the UVB-protective efficacy of silver nanoparticles in human keratinocytes.
BMC cancer Sep, 2015 | Pubmed ID: 26373391
p-21 activated kinase 4 (PAK4) maintains stem cell-like phenotypes in pancreatic cancer cells through activation of STAT3 signaling.
Cancer letters Jan, 2016 | Pubmed ID: 26546043
MYB is a novel regulator of pancreatic tumour growth and metastasis.
British journal of cancer Dec, 2015 | Pubmed ID: 26657649
Pancreatic Cancer Exosomes: Shedding Off for a Meaningful Journey.
Pancreatic disorders & therapy , 2016 | Pubmed ID: 27030812
Molecular Targets of Honokiol: A Promising Phytochemical for Effective Cancer Management.
The Enzymes , 2014 | Pubmed ID: 27102704
MYB Promotes Desmoplasia in Pancreatic Cancer through Direct Transcriptional Up-regulation and Cooperative Action of Sonic Hedgehog and Adrenomedullin.
The Journal of biological chemistry 07, 2016 | Pubmed ID: 27246849
Deep sequencing and in silico analyses identify MYB-regulated gene networks and signaling pathways in pancreatic cancer.
Scientific reports 06, 2016 | Pubmed ID: 27354262
Honokiol suppresses pancreatic tumor growth, metastasis and desmoplasia by interfering with tumor-stromal cross-talk.
Carcinogenesis 11, 2016 | Pubmed ID: 27609457
Comparative analysis of the relative potential of silver, Zinc-oxide and titanium-dioxide nanoparticles against UVB-induced DNA damage for the prevention of skin carcinogenesis.
Cancer letters 12, 2016 | Pubmed ID: 27693632
Racial disparities in prostate cancer: a molecular perspective.
Frontiers in bioscience (Landmark edition) 01, 2017 | Pubmed ID: 27814645
Epigenetic basis of cancer health disparities: Looking beyond genetic differences.
Biochimica et biophysica acta. Reviews on cancer Aug, 2017 | Pubmed ID: 28108348
Biological basis of cancer health disparities: resources and challenges for research.
American journal of cancer research , 2017 | Pubmed ID: 28123843
Exosomes confer chemoresistance to pancreatic cancer cells by promoting ROS detoxification and miR-155-mediated suppression of key gemcitabine-metabolising enzyme, DCK.
British journal of cancer Feb, 2017 | Pubmed ID: 28152544
Resistin potentiates chemoresistance and stemness of breast cancer cells: Implications for racially disparate therapeutic outcomes.
Cancer letters 06, 2017 | Pubmed ID: 28302531
Emerging evidence for the role of differential tumor microenvironment in breast cancer racial disparity: a closer look at the surroundings.
Carcinogenesis 08, 2017 | Pubmed ID: 28430867
MicroRNAs in gynecological cancers: Small molecules with big implications.
Cancer letters 10, 2017 | Pubmed ID: 28549791
Exosomal Markers (CD63 and CD9) Expression Pattern Using Immunohistochemistry in Resected Malignant and Nonmalignant Pancreatic Specimens.
Pancreas Jul, 2017 | Pubmed ID: 28609367
Racial health disparities in ovarian cancer: not just black and white.
Journal of ovarian research Sep, 2017 | Pubmed ID: 28931403
ETV4 Facilitates Cell-Cycle Progression in Pancreatic Cells through Transcriptional Regulation of Cyclin D1.
Molecular cancer research : MCR 02, 2018 | Pubmed ID: 29117940
Germline pharmacogenomics of DPYD*9A (c.85T>C) variant in patients with gastrointestinal malignancies treated with fluoropyrimidines.
Journal of gastrointestinal oncology Jun, 2018 | Pubmed ID: 29998006
ETV4: an emerging target in pancreatic cancer.
Oncoscience Sep, 2018 | Pubmed ID: 30460327
Revisiting the Clinical Importance of DPYD*9A (c.85T>C) Variant of Dihydropyrimidine Dehydrogenase (DPYD) Gene in Patients Treated with Fluoropyrimidine-Based Chemotherapy.
Journal of molecular biomarkers & diagnosis , 2018 | Pubmed ID: 31105991
The Prevalence of DPYD*9A(c.85T>C) Genotype and the Genotype-Phenotype Correlation in Patients with Gastrointestinal Malignancies Treated With Fluoropyrimidines: Updated Analysis.
Clinical colorectal cancer 09, 2019 | Pubmed ID: 31160238
Exosomal markers (CD63 and CD9) expression and their prognostic significance using immunohistochemistry in patients with pancreatic ductal adenocarcinoma.
Journal of gastrointestinal oncology Aug, 2019 | Pubmed ID: 31392050
Hypoxia alters the release and size distribution of extracellular vesicles in pancreatic cancer cells to support their adaptive survival.
Journal of cellular biochemistry 01, 2020 | Pubmed ID: 31407387
Modulation of the tumor microenvironment by natural agents: implications for cancer prevention and therapy.
Seminars in cancer biology May, 2020 | Pubmed ID: 32470379
Epidermal growth factor receptor-activating mutation(E746_T751>VP) in pancreatic ductal adenocarcinoma responds to erlotinib, followed by epidermal growth factor receptor resistance-mediating mutation (A647T): A case report and literature review.
Journal of cancer research and therapeutics Jul-Sep, 2020 | Pubmed ID: 32930150
The prevalence and clinical relevance of 2R/2R TYMS genotype in patients with gastrointestinal malignancies treated with fluoropyrimidine-based chemotherapy regimens.
The pharmacogenomics journal 06, 2021 | Pubmed ID: 33608662
Clinicopathologic significance and race-specific prognostic association of MYB overexpression in ovarian cancer.
Scientific reports 06, 2021 | Pubmed ID: 34145334
The impact of neoadjuvant concurrent chemoradiation on exosomal markers (CD63 and CD9) expression and their prognostic significance in patients with rectal adenocarcinoma.
Oncotarget Jul, 2021 | Pubmed ID: 34316329
Platinum-resistant ovarian cancer: From drug resistance mechanisms to liquid biopsy-based biomarkers for disease management.
Seminars in cancer biology 12, 2021 | Pubmed ID: 34418576
MYB interacts with androgen receptor, sustains its ligand-independent activation and promotes castration resistance in prostate cancer.
British journal of cancer Nov, 2021 | Pubmed ID: 34837075
Determining the Size Distribution and Integrity of Extracellular Vesicles by Dynamic Light Scattering.
Methods in molecular biology (Clifton, N.J.) , 2022 | Pubmed ID: 35044664
Alyson Nguyen*,1,
Keith Battle*,2,3,
Sunita S. Paudel*,2,3,
Ningyong Xu2,
Jessica Bell3,
Linn Ayers3,
Cassandra Chapman4,
Ajay P. Singh5,
Srinivas Palanki6,
Thomas Rich3,7,
Diego F. Alvarez8,
Troy Stevens2,3,
Dhananjay T. Tambe3,4,7
1Biomedical Sciences, Pat Capps Covey College of Allied Health Professions, University of South Alabama,
2Department of Physiology and Cell Biology, College of Medicine, University of South Alabama,
3Center for Lung Biology, College of Medicine, University of South Alabama,
4William B. Burnsed Jr. Mechanical, Aerospace, and Biomedical Engineering Department, College of Engineering, University of South Alabama,
5Mitchell Cancer Institute, College of Medicine, University of South Alabama,
6Department of Chemical and Biomedical Engineering, West Virginia University,
7Department of Pharmacology, College of Medicine, University of South Alabama,
8Department of Physiology & Pharmacology, College of Osteopathic Medicine, Sam Houston State University
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