Matthias Mack

3-Methylglutaconyl-CoA hydratase from Acinetobacter sp.

Riboflavin analogs and inhibitors of riboflavin biosynthesis.

Biochemical characterization of human 3-methylglutaconyl-CoA hydratase and its role in leucine metabolism.

Characterization of riboflavin (vitamin B2) transport proteins from Bacillus subtilis and Corynebacterium glutamicum.

The bifunctional flavokinase/flavin adenine dinucleotide synthetase from Streptomyces davawensis produces inactive flavin cofactors and is not involved in resistance to the antibiotic roseoflavin.

A high-throughput microtiter plate-based screening method for the detection of full-length recombinant proteins.

The RFN riboswitch of Bacillus subtilis is a target for the antibiotic roseoflavin produced by Streptomyces davawensis.

Comparison of two expression platforms in respect to protein yield and quality: Pichia pastoris versus Pichia angusta.

A novel N,N-8-amino-8-demethyl-D-riboflavin Dimethyltransferase (RosA) catalyzing the two terminal steps of roseoflavin biosynthesis in Streptomyces davawensis.

The antibiotics roseoflavin and 8-demethyl-8-amino-riboflavin from Streptomyces davawensis are metabolized by human flavokinase and human FAD synthetase.

RibM from Streptomyces davawensis is a riboflavin/roseoflavin transporter and may be useful for the optimization of riboflavin production strains.

A highly specialized flavin mononucleotide riboswitch responds differently to similar ligands and confers roseoflavin resistance to Streptomyces davawensis.

Bacteriophage T7 RNA polymerase-based expression in Pichia pastoris.

Thermodynamic and Probabilistic Metabolic Control Analysis of Riboflavin (Vitamin B₂) Biosynthesis in Bacteria.

A dual control mechanism synchronizes riboflavin and sulphur metabolism in Bacillus subtilis.

Identification of the Key Enzyme of Roseoflavin Biosynthesis.

Uptake and Metabolism of Antibiotics Roseoflavin and 8-Demethyl-8-Aminoriboflavin in Riboflavin-Auxotrophic Listeria monocytogenes.

Dual-Targeting Small-Molecule Inhibitors of the Staphylococcus aureus FMN Riboswitch Disrupt Riboflavin Homeostasis in an Infectious Setting.

Taxonomic analyses of members of the Streptomyces cinnabarinus cluster, description of Streptomyces cinnabarigriseus sp. nov. and Streptomyces davaonensis sp. nov.

Formation of 3-hydroxyglutaric acid in glutaric aciduria type I: in vitro participation of medium chain acyl-CoA dehydrogenase.

Metabolic engineering of roseoflavin-overproducing microorganisms.

Rational engineering of transcriptional riboswitches leads to enhanced metabolite levels in Bacillus subtilis.

Engineering of Synechococcus sp. strain PCC 7002 for the photoautotrophic production of light-sensitive riboflavin (vitamin B2).