David H. Koch Institute for Integrative Cancer Research
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Parallel synthesis and biophysical characterization of a degradable polymer library for gene delivery.
Journal of the American Chemical Society May, 2003 | Pubmed ID: 12720443
Semi-automated synthesis and screening of a large library of degradable cationic polymers for gene delivery.
Angewandte Chemie (International ed. in English) Jul, 2003 | Pubmed ID: 12866105
Synthesis of poly(beta-amino ester)s optimized for highly effective gene delivery.
Bioconjugate chemistry Sep-Oct, 2003 | Pubmed ID: 13129402
Degradable poly(amino alcohol esters) as potential DNA vectors with low cytotoxicity.
Biomacromolecules Nov-Dec, 2003 | Pubmed ID: 14606906
pH-triggered release of macromolecules from spray-dried polymethacrylate microparticles.
Pharmaceutical research Oct, 2003 | Pubmed ID: 14620503
Nanoliter-scale synthesis of arrayed biomaterials and application to human embryonic stem cells.
Nature biotechnology Jul, 2004 | Pubmed ID: 15195101
Poly-beta amino ester-containing microparticles enhance the activity of nonviral genetic vaccines.
Proceedings of the National Academy of Sciences of the United States of America Jun, 2004 | Pubmed ID: 15210954
pH-triggered microparticles for peptide vaccination.
Journal of immunology (Baltimore, Md. : 1950) Aug, 2004 | Pubmed ID: 15294974
Materials science. Smart biomaterials.
Science (New York, N.Y.) Sep, 2004 | Pubmed ID: 15448260
A polymer library approach to suicide gene therapy for cancer.
Proceedings of the National Academy of Sciences of the United States of America Nov, 2004 | Pubmed ID: 15520369
Structure/property studies of polymeric gene delivery using a library of poly(beta-amino esters).
Molecular therapy : the journal of the American Society of Gene Therapy Mar, 2005 | Pubmed ID: 15727939
Biomaterial microarrays: rapid, microscale screening of polymer-cell interaction.
Biomaterials Aug, 2005 | Pubmed ID: 15763269
Beta-amino ester polymers facilitate in vivo DNA transfection and adjuvant plasmid DNA immunization.
Molecular therapy : the journal of the American Society of Gene Therapy Jul, 2005 | Pubmed ID: 15963932
Direct patterning of mammalian cells onto porous tissue engineering substrates using agarose stamps.
Biomaterials Dec, 2005 | Pubmed ID: 15979701
Biodegradable polymeric vectors for gene delivery to human endothelial cells.
Bioconjugate chemistry Sep-Oct, 2006 | Pubmed ID: 16984124
Synthesis of poly(beta-amino ester)s with thiol-reactive side chains for DNA delivery.
Journal of the American Chemical Society Oct, 2006 | Pubmed ID: 17002366
Electrostatic ligand coatings of nanoparticles enable ligand-specific gene delivery to human primary cells.
Nano letters Apr, 2007 | Pubmed ID: 17362046
Rapid optimization of gene delivery by parallel end-modification of poly(beta-amino ester)s.
Molecular therapy : the journal of the American Society of Gene Therapy Jul, 2007 | Pubmed ID: 17375071
Nanoparticulate delivery of suicide DNA to murine prostate and prostate tumors.
The Prostate Jun, 2007 | Pubmed ID: 17427200
Effective RNAi-mediated gene silencing without interruption of the endogenous microRNA pathway.
Nature Oct, 2007 | Pubmed ID: 17898712
Gene delivery properties of end-modified poly(beta-amino ester)s.
Bioconjugate chemistry Nov-Dec, 2007 | Pubmed ID: 17929884
TOF-SIMS analysis of a 576 micropatterned copolymer array to reveal surface moieties that control wettability.
Analytical chemistry Jan, 2008 | Pubmed ID: 18044847
Nanomechanical control of cell rolling in two dimensions through surface patterning of receptors.
Nano letters Apr, 2008 | Pubmed ID: 18321075
A combinatorial library of lipid-like materials for delivery of RNAi therapeutics.
Nature biotechnology May, 2008 | Pubmed ID: 18438401
Heme oxygenase-1 is an anti-inflammatory host factor that promotes murine plasmodium liver infection.
Cell host & microbe May, 2008 | Pubmed ID: 18474360
A Combinatorial Polymer Library Approach Yields Insight into Nonviral Gene Delivery.
Accounts of chemical research May, 2008 | Pubmed ID: 18507402
Nanoparticle delivery of suicide DNA for epithelial ovarian cancer therapy.
Advances in experimental medicine and biology , 2008 | Pubmed ID: 18546630
Therapeutic RNAi targeting PCSK9 acutely lowers plasma cholesterol in rodents and LDL cholesterol in nonhuman primates.
Proceedings of the National Academy of Sciences of the United States of America Aug, 2008 | Pubmed ID: 18695239
Nanoparticles for gene transfer to human embryonic stem cell colonies.
Nano letters Oct, 2008 | Pubmed ID: 18754690
Delivery of small interfering RNA for inhibition of endothelial cell apoptosis by hypoxia and serum deprivation.
Biochemical and biophysical research communications Nov, 2008 | Pubmed ID: 18765230
Assessing siRNA pharmacodynamics in a luciferase-expressing mouse.
Molecular therapy : the journal of the American Society of Gene Therapy Dec, 2008 | Pubmed ID: 18781145
Cell-compatible, multicomponent protein arrays with subcellular feature resolution.
Small (Weinheim an der Bergstrasse, Germany) Oct, 2008 | Pubmed ID: 18844310
Nanoparticulate delivery of diphtheria toxin DNA effectively kills Mesothelin expressing pancreatic cancer cells.
Cancer biology & therapy Oct, 2008 | Pubmed ID: 19039293
Poly(beta-amino esters): procedures for synthesis and gene delivery.
Methods in molecular biology (Clifton, N.J.) , 2009 | Pubmed ID: 19085119
Knocking down barriers: advances in siRNA delivery.
Nature reviews. Drug discovery Feb, 2009 | Pubmed ID: 19180106
Claudin-3 gene silencing with siRNA suppresses ovarian tumor growth and metastasis.
Proceedings of the National Academy of Sciences of the United States of America Mar, 2009 | Pubmed ID: 19208807
Development of lipidoid-siRNA formulations for systemic delivery to the liver.
Molecular therapy : the journal of the American Society of Gene Therapy May, 2009 | Pubmed ID: 19259063
Preparation of monodisperse biodegradable polymer microparticles using a microfluidic flow-focusing device for controlled drug delivery.
Small (Weinheim an der Bergstrasse, Germany) Jul, 2009 | Pubmed ID: 19296563
A novel high-throughput cell-based method for integrated quantification of type I interferons and in vitro screening of immunostimulatory RNA drug delivery.
Biotechnology and bioengineering Jul, 2009 | Pubmed ID: 19338049
Gold, poly(beta-amino ester) nanoparticles for small interfering RNA delivery.
Nano letters Jun, 2009 | Pubmed ID: 19422265
Locally delivered growth factor enhances the angiogenic efficacy of adipose-derived stromal cells transplanted to ischemic limbs.
Stem cells (Dayton, Ohio) Aug, 2009 | Pubmed ID: 19544425
High-throughput membrane surface modification to control NOM fouling.
Environmental science & technology May, 2009 | Pubmed ID: 19544900
Drug delivery-mediated control of RNA immunostimulation.
Molecular therapy : the journal of the American Society of Gene Therapy Sep, 2009 | Pubmed ID: 19584813
Minicells overcome tumor drug-resistance.
Nature biotechnology Jul, 2009 | Pubmed ID: 19587665
High throughput optimization of stem cell microenvironments.
Combinatorial chemistry & high throughput screening Jul, 2009 | Pubmed ID: 19601753
Nanoparticle-delivered suicide gene therapy effectively reduces ovarian tumor burden in mice.
Cancer research Aug, 2009 | Pubmed ID: 19643734
Microfabrication of homogenous, asymmetric cell-laden hydrogel capsules.
Biomaterials Dec, 2009 | Pubmed ID: 19800116
Genetic engineering of human stem cells for enhanced angiogenesis using biodegradable polymeric nanoparticles.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2010 | Pubmed ID: 19805054
Nanoparticle-delivered multimeric soluble CD40L DNA combined with Toll-Like Receptor agonists as a treatment for melanoma.
PloS one , 2009 | Pubmed ID: 19812695
High throughput methods applied in biomaterial development and discovery.
Biomaterials Jan, 2010 | Pubmed ID: 19815273
Tissue-specific gene delivery via nanoparticle coating.
Biomaterials Feb, 2010 | Pubmed ID: 19850333
Lipid-like materials for low-dose, in vivo gene silencing.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2010 | Pubmed ID: 20080679
Nanoparticulate cellular patches for cell-mediated tumoritropic delivery.
ACS nano Feb, 2010 | Pubmed ID: 20121215
Electrostatic surface modifications to improve gene delivery.
Expert opinion on drug delivery Apr, 2010 | Pubmed ID: 20201712
Rapid biocompatibility analysis of materials via in vivo fluorescence imaging of mouse models.
PloS one , 2010 | Pubmed ID: 20386609
Combinatorial extracellular matrices for human embryonic stem cell differentiation in 3D.
Biomacromolecules Aug, 2010 | Pubmed ID: 20614932
Combinatorial approach to determine functional group effects on lipidoid-mediated siRNA delivery.
Bioconjugate chemistry Aug, 2010 | Pubmed ID: 20715849
Combinatorial development of biomaterials for clonal growth of human pluripotent stem cells.
Nature materials Sep, 2010 | Pubmed ID: 20729850
CanScript, an 18-Base pair DNA sequence, boosts tumor cell-specific promoter activity: implications for targeted gene therapy.
Cancer biology & therapy Nov, 2010 | Pubmed ID: 20798601
A high throughput micro-array system of polymer surfaces for the manipulation of primary pancreatic islet cells.
Biomaterials Dec, 2010 | Pubmed ID: 20828808
Polymer surface functionalities that control human embryoid body cell adhesion revealed by high throughput surface characterization of combinatorial material microarrays.
Biomaterials Dec, 2010 | Pubmed ID: 20832108
An injectable thiol-acrylate poly(ethylene glycol) hydrogel for sustained release of methylprednisolone sodium succinate.
Biomaterials Jan, 2011 | Pubmed ID: 20880573
High throughput surface characterization: A review of a new tool for screening prospective biomedical material arrays.
Journal of drug targeting Dec, 2010 | Pubmed ID: 20945971
DNA-controlled assembly of a NaTl lattice structure from gold nanoparticles and protein nanoparticles.
Nature materials Nov, 2010 | Pubmed ID: 20953184
Real-time in vivo detection of biomaterial-induced reactive oxygen species.
Biomaterials Mar, 2011 | Pubmed ID: 21146868
A novel family of biodegradable poly(ester amide) elastomers.
Advanced materials (Deerfield Beach, Fla.) Mar, 2011 | Pubmed ID: 21394790
Spatiotemporal effects of a controlled-release anti-inflammatory drug on the cellular dynamics of host response.
Biomaterials Jul, 2011 | Pubmed ID: 21429573
Chondrogenic priming adipose-mesenchymal stem cells for cartilage tissue regeneration.
Pharmaceutical research Jun, 2011 | Pubmed ID: 21494923
Development of cationic polymer coatings to regulate foreign-body responses.
Advanced materials (Deerfield Beach, Fla.) Jun, 2011 | Pubmed ID: 21567481
Degradable polyelectrolyte multilayers that promote the release of siRNA.
Langmuir : the ACS journal of surfaces and colloids Jun, 2011 | Pubmed ID: 21574582
Five years of siRNA delivery: spotlight on gold nanoparticles.
Small (Weinheim an der Bergstrasse, Germany) Jul, 2011 | Pubmed ID: 21681985
Poly(β-amino ester)-DNA complexes: time-resolved fluorescence and cellular transfection studies.
Journal of controlled release : official journal of the Controlled Release Society Sep, 2011 | Pubmed ID: 21699928
Synergistic silencing: combinations of lipid-like materials for efficacious siRNA delivery.
Molecular therapy : the journal of the American Society of Gene Therapy Sep, 2011 | Pubmed ID: 21750531
Combinatorial synthesis of chemically diverse core-shell nanoparticles for intracellular delivery.
Proceedings of the National Academy of Sciences of the United States of America Aug, 2011 | Pubmed ID: 21784981
Directing human embryonic stem cell differentiation by non-viral delivery of siRNA in 3D culture.
Biomaterials Nov, 2011 | Pubmed ID: 21835461
Nanoparticles targeting the infarcted heart.
Nano letters Oct, 2011 | Pubmed ID: 21899318
Islets transplanted in immunoisolation devices: a review of the progress and the challenges that remain.
Endocrine reviews Dec, 2011 | Pubmed ID: 21951347
The influence of scaffold elasticity on germ layer specification of human embryonic stem cells.
Biomaterials Dec, 2011 | Pubmed ID: 21963156
Therapeutic siRNA silencing in inflammatory monocytes in mice.
Nature biotechnology Nov, 2011 | Pubmed ID: 21983520
Surface-engineered substrates for improved human pluripotent stem cell culture under fully defined conditions.
Proceedings of the National Academy of Sciences of the United States of America Nov, 2011 | Pubmed ID: 22065768
Combinatorial library of lipidoids for in vitro DNA delivery.
Bioconjugate chemistry Jan, 2012 | Pubmed ID: 22148515
Alkane-modified short polyethyleneimine for siRNA delivery.
Journal of controlled release : official journal of the Controlled Release Society Dec, 2011 | Pubmed ID: 22155553
Treating metastatic cancer with nanotechnology.
Nature reviews. Cancer Jan, 2012 | Pubmed ID: 22193407
Action and Reaction: The Biological Response to siRNA and Its Delivery Vehicles.
Molecular therapy : the journal of the American Society of Gene Therapy Jan, 2012 | Pubmed ID: 22252451
Origins of tumor-associated macrophages and neutrophils.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2012 | Pubmed ID: 22308361
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