Arminja N. Kettenbach

Plk1 regulates the kinesin-13 protein Kif2b to promote faithful chromosome segregation.

Structures of Down syndrome kinases, DYRKs, reveal mechanisms of kinase activation and substrate recognition.

Dueling kinases regulate cell size at division through the SAD kinase Cdr2.

Yeast vacuolar HOPS, regulated by its kinase, exploits affinities for acidic lipids and Rab:GTP for membrane binding and to catalyze tethering and fusion.

SPECHT - single-stage phosphopeptide enrichment and stable-isotope chemical tagging: quantitative phosphoproteomics of insulin action in muscle.

Quantitative phosphoproteomics reveals pathways for coordination of cell growth and division by the conserved fission yeast kinase pom1.

Quantitative phosphoproteomics reveals new roles for the protein phosphatase PP6 in mitotic cells.

Phosphorylation Regulates Id2 Degradation and Mediates the Proliferation of Neural Precursor Cells.

Identification of Candidate Cyclin-dependent kinase 1 (Cdk1) Substrates in Mitosis by Quantitative Phosphoproteomics.

HOPS catalyzes the interdependent assembly of each vacuolar SNARE into a SNARE complex.

A bifurcated signaling cascade of NIMA-related kinases controls distinct kinesins in anaphase.

Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.

Cyclin A/Cdk1 modulates Plk1 activity in prometaphase to regulate kinetochore-microtubule attachment stability.

PP1:Tautomycetin Complex Reveals a Path toward the Development of PP1-Specific Inhibitors.

Identification of Candidate Casein Kinase 2 Substrates in Mitosis by Quantitative Phosphoproteomics.

Mechanisms Connecting the Conserved Protein Kinases Ssp1, Kin1, and Pom1 in Fission Yeast Cell Polarity and Division.

Therapeutically targeting tumor microenvironment-mediated drug resistance in estrogen receptor-positive breast cancer.

Coordination of Protein Kinase and Phosphoprotein Phosphatase Activities in Mitosis.

Global assessment of its network dynamics reveals that the kinase Plk1 inhibits the phosphatase PP6 to promote Aurora A activity.

Aurora B opposes PP1 function in mitosis by phosphorylating the conserved PP1-binding RVxF motif in PP1 regulatory proteins.

Comparative Analysis of Mutant Huntingtin Binding Partners in Yeast Species.

A Quantitative Chemical Proteomic Strategy for Profiling Phosphoprotein Phosphatases from Yeast to Humans.

Identification of the substrate recruitment mechanism of the muscle glycogen protein phosphatase 1 holoenzyme.

The Phospho-Code Determining Circadian Feedback Loop Closure and Output in Neurospora.

A complex containing lysine-acetylated actin inhibits the formin INF2.

R-DeeP: Proteome-wide and Quantitative Identification of RNA-Dependent Proteins by Density Gradient Ultracentrifugation.

Estrogen therapy induces an unfolded protein response to drive cell death in ER+ breast cancer.

A Transcriptionally Definable Subgroup of Triple-Negative Breast and Ovarian Cancer Samples Shows Sensitivity to HSP90 Inhibition.

A Consensus Binding Motif for the PP4 Protein Phosphatase.

Leveraging New Definitions of the LxVP SLiM To Discover Novel Calcineurin Regulators and Substrates.

A mechanism for how Cdr1/Nim1 kinase promotes mitotic entry by inhibiting Wee1.

Identification, quantification and bioinformatic analysis of RNA-dependent proteins by RNase treatment and density gradient ultracentrifugation using R-DeeP.

A dynamic charge-charge interaction modulates PP2A:B56 substrate recruitment.

Mechanisms of site-specific dephosphorylation and kinase opposition imposed by PP2A regulatory subunits.

Fission yeast Pak1 phosphorylates anillin-like Mid1 for spatial control of cytokinesis.

Quantitative kinase and phosphatase profiling reveal that CDK1 phosphorylates PP2Ac to promote mitotic entry.

Effects of carboxyl-terminal methylation on holoenzyme function of the PP2A subfamily.

Receptor-mediated clustering of FIP200 bypasses the role of LC3 lipidation in autophagy.

A disorder-related variant (E420K) of a PP2A-regulatory subunit (PPP2R5D) causes constitutively active AKT-mTOR signaling and uncoordinated cell growth.

Coupling of Cdc20 inhibition and activation by BubR1.

Use of Mitotic Protein Kinase Inhibitors and Phospho-Specific Antibodies to Monitor Protein Phosphorylation During the Cell Cycle.

Selective dephosphorylation by PP2A-B55 directs the meiosis I-meiosis II transition in oocytes.

Affinity-based profiling of endogenous phosphoprotein phosphatases by mass spectrometry.

A complex of BRCA2 and PP2A-B56 is required for DNA repair by homologous recombination.

Regulation of PP2A, PP4, and PP6 holoenzyme assembly by carboxyl-terminal methylation.

The Candida albicans Cdk8-dependent phosphoproteome reveals repression of hyphal growth through a Flo8-dependent pathway.

Myosin II proteins are required for organization of calcium-induced actin networks upstream of mitochondrial division.