Arminja N. Kettenbach

Department of Biochemistry and Cell Biology, Geisel School of Medicine at Dartmouth

Affiliated withGeisel School of Medicine at Dartmouth Norris Cotton Cancer Center

Research Area

BiochemistryUnit 1

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2022

Other Publications

Article	Year
Plk1 regulates the kinesin-13 protein Kif2b to promote faithful chromosome segregation. Molecular biology of the cell\| PubMed ID: 22535524	2012
Structures of Down syndrome kinases, DYRKs, reveal mechanisms of kinase activation and substrate recognition. Structure (London, England : 1993)\| PubMed ID: 23665168	2013
Dueling kinases regulate cell size at division through the SAD kinase Cdr2. Current biology : CB\| PubMed ID: 24508166	2014
Yeast vacuolar HOPS, regulated by its kinase, exploits affinities for acidic lipids and Rab:GTP for membrane binding and to catalyze tethering and fusion. Molecular biology of the cell\| PubMed ID: 25411340	2015
SPECHT - single-stage phosphopeptide enrichment and stable-isotope chemical tagging: quantitative phosphoproteomics of insulin action in muscle. Journal of proteomics\| PubMed ID: 25463755	2015
Quantitative phosphoproteomics reveals pathways for coordination of cell growth and division by the conserved fission yeast kinase pom1. Molecular & cellular proteomics : MCP\| PubMed ID: 25720772	2015
Quantitative phosphoproteomics reveals new roles for the protein phosphatase PP6 in mitotic cells. Science signaling\| PubMed ID: 26462736	2015
Phosphorylation Regulates Id2 Degradation and Mediates the Proliferation of Neural Precursor Cells. Stem cells (Dayton, Ohio)\| PubMed ID: 26756672	2016
Identification of Candidate Cyclin-dependent kinase 1 (Cdk1) Substrates in Mitosis by Quantitative Phosphoproteomics. Molecular & cellular proteomics : MCP\| PubMed ID: 27134283	2016
HOPS catalyzes the interdependent assembly of each vacuolar SNARE into a SNARE complex. Molecular biology of the cell\| PubMed ID: 28148647	2017
A bifurcated signaling cascade of NIMA-related kinases controls distinct kinesins in anaphase. The Journal of cell biology\| PubMed ID: 28630147	2017
Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 28807998	2017
Cyclin A/Cdk1 modulates Plk1 activity in prometaphase to regulate kinetochore-microtubule attachment stability. eLife\| PubMed ID: 29154753	2017
PP1:Tautomycetin Complex Reveals a Path toward the Development of PP1-Specific Inhibitors. Journal of the American Chemical Society\| PubMed ID: 29156132	2017
Identification of Candidate Casein Kinase 2 Substrates in Mitosis by Quantitative Phosphoproteomics. Frontiers in cell and developmental biology\| PubMed ID: 29214152	2017
Mechanisms Connecting the Conserved Protein Kinases Ssp1, Kin1, and Pom1 in Fission Yeast Cell Polarity and Division. Current biology : CB\| PubMed ID: 29249658	2018
Therapeutically targeting tumor microenvironment-mediated drug resistance in estrogen receptor-positive breast cancer. The Journal of experimental medicine\| PubMed ID: 29436393	2018
Coordination of Protein Kinase and Phosphoprotein Phosphatase Activities in Mitosis. Frontiers in cell and developmental biology\| PubMed ID: 29623276	2018
Global assessment of its network dynamics reveals that the kinase Plk1 inhibits the phosphatase PP6 to promote Aurora A activity. Science signaling\| PubMed ID: 29764989	2018
Aurora B opposes PP1 function in mitosis by phosphorylating the conserved PP1-binding RVxF motif in PP1 regulatory proteins. Science signaling\| PubMed ID: 29764992	2018
Comparative Analysis of Mutant Huntingtin Binding Partners in Yeast Species. Scientific reports\| PubMed ID: 29934597	2018
A Quantitative Chemical Proteomic Strategy for Profiling Phosphoprotein Phosphatases from Yeast to Humans. Molecular & cellular proteomics : MCP\| PubMed ID: 30228194	2018
Identification of the substrate recruitment mechanism of the muscle glycogen protein phosphatase 1 holoenzyme. Science advances\| PubMed ID: 30443599	2018
The Phospho-Code Determining Circadian Feedback Loop Closure and Output in Neurospora. Molecular cell\| PubMed ID: 30954403	2019
A complex containing lysine-acetylated actin inhibits the formin INF2. Nature cell biology\| PubMed ID: 30962575	2019
R-DeeP: Proteome-wide and Quantitative Identification of RNA-Dependent Proteins by Density Gradient Ultracentrifugation. Molecular cell\| PubMed ID: 31076284	2019
Estrogen therapy induces an unfolded protein response to drive cell death in ER+ breast cancer. Molecular oncology\| PubMed ID: 31180176	2019
A Transcriptionally Definable Subgroup of Triple-Negative Breast and Ovarian Cancer Samples Shows Sensitivity to HSP90 Inhibition. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 31558472	2020
A Consensus Binding Motif for the PP4 Protein Phosphatase. Molecular cell\| PubMed ID: 31585692	2019
Leveraging New Definitions of the LxVP SLiM To Discover Novel Calcineurin Regulators and Substrates. ACS chemical biology\| PubMed ID: 31633908	2019
A mechanism for how Cdr1/Nim1 kinase promotes mitotic entry by inhibiting Wee1. Molecular biology of the cell\| PubMed ID: 31644361	2019
Identification, quantification and bioinformatic analysis of RNA-dependent proteins by RNase treatment and density gradient ultracentrifugation using R-DeeP. Nature protocols\| PubMed ID: 32094787	2020
A dynamic charge-charge interaction modulates PP2A:B56 substrate recruitment. eLife\| PubMed ID: 32195664	2020
Mechanisms of site-specific dephosphorylation and kinase opposition imposed by PP2A regulatory subunits. The EMBO journal\| PubMed ID: 32400009	2020
Fission yeast Pak1 phosphorylates anillin-like Mid1 for spatial control of cytokinesis. The Journal of cell biology\| PubMed ID: 32421151	2020
Quantitative kinase and phosphatase profiling reveal that CDK1 phosphorylates PP2Ac to promote mitotic entry. Science signaling\| PubMed ID: 32900880	2020
Effects of carboxyl-terminal methylation on holoenzyme function of the PP2A subfamily. Biochemical Society transactions\| PubMed ID: 33125487	2020
Receptor-mediated clustering of FIP200 bypasses the role of LC3 lipidation in autophagy. The EMBO journal\| PubMed ID: 33226137	2020
A disorder-related variant (E420K) of a PP2A-regulatory subunit (PPP2R5D) causes constitutively active AKT-mTOR signaling and uncoordinated cell growth. The Journal of biological chemistry\| PubMed ID: 33482199	2021
Coupling of Cdc20 inhibition and activation by BubR1. The Journal of cell biology\| PubMed ID: 33819340	2021
Use of Mitotic Protein Kinase Inhibitors and Phospho-Specific Antibodies to Monitor Protein Phosphorylation During the Cell Cycle. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 34085225	2021
Selective dephosphorylation by PP2A-B55 directs the meiosis I-meiosis II transition in oocytes. eLife\| PubMed ID: 34342579	2021
Affinity-based profiling of endogenous phosphoprotein phosphatases by mass spectrometry. Nature protocols\| PubMed ID: 34518704	2021
A complex of BRCA2 and PP2A-B56 is required for DNA repair by homologous recombination. Nature communications\| PubMed ID: 34593815	2021
Regulation of PP2A, PP4, and PP6 holoenzyme assembly by carboxyl-terminal methylation. Scientific reports\| PubMed ID: 34845248	2021
The Candida albicans Cdk8-dependent phosphoproteome reveals repression of hyphal growth through a Flo8-dependent pathway. PLoS genetics\| PubMed ID: 34982775	2022
Myosin II proteins are required for organization of calcium-induced actin networks upstream of mitochondrial division. Molecular biology of the cell\| PubMed ID: 35427150	2022