Robert M. Graham

Phe(303) in TMVI of the alpha(1B)-adrenergic receptor is a key residue coupling TM helical movements to G-protein activation.

Mutation of a single TMVI residue, Phe(282), in the beta(2)-adrenergic receptor results in structurally distinct activated receptor conformations.

Molecular mechanisms of inherited cardiomyopathies.

Evolutionary specialization of a tryptophan indole group for transition-state stabilization by eukaryotic transglutaminases.

Involvement of chymase-mediated angiotensin II generation in blood pressure regulation.

Molecular basis of exopeptidase activity in the C-terminal domain of human angiotensin I-converting enzyme: insights into the origins of its exopeptidase activity.

The alpha(1D)-adrenergic receptor: cinderella or ugly stepsister.

Mutation of a critical arginine in the GTP-binding site of transglutaminase 2 disinhibits intracellular cross-linking activity.

Cross-linking transglutaminases with G protein-coupled receptor signaling.

Profound thrombocytopenia related to G-CSF.

Actions and therapeutic potential of G-CSF and GM-CSF in cardiovascular disease.

Mechanism of allosteric regulation of transglutaminase 2 by GTP.

Wide turn diversity in protein transmembrane helices implications for G-protein-coupled receptor and other polytopic membrane protein structure and function.

Safety and efficacy of consecutive cycles of granulocyte-colony stimulating factor, and an intracoronary CD133+ cell infusion in patients with chronic refractory ischemic heart disease: the G-CSF in angina patients with IHD to stimulate neovascularization (GAIN I) trial.

Transglutaminases and disease: lessons from genetically engineered mouse models and inherited disorders.

Reproducibility of adenosine stress cardiovascular magnetic resonance in multi-vessel symptomatic coronary artery disease.

The elusive π-helix.

A recombinant human neuregulin-1 peptide improves preservation of the rodent heart after prolonged hypothermic storage.

Regulation of murine cardiac contractility by activation of α(1A)-adrenergic receptor-operated Ca(2+) entry.

The ontogeny of cardiac regeneration.

Granulocyte colony stimulating factor in chronic angina to stimulate neovascularisation: a placebo controlled crossover trial.

Functional Characterization of a Novel Mutation in NKX2-5 Associated with Congenital Heart Disease and Adult-Onset Cardiomyopathy.

Glucose homeostasis in mice is transglutaminase 2 independent.

A proliferative burst during preadolescence establishes the final cardiomyocyte number.

RhoA/ROCK signaling and pleiotropic α1A-adrenergic receptor regulation of cardiac contractility.

Thyroid hormone action in postnatal heart development.

Introduction to the special issue on heart regeneration and rejuvenation.

Irreversible triggers for hypertrophic cardiomyopathy are established in the early postnatal period.

Rapid Knockout and Reporter Mouse Line Generation and Breeding Colony Establishment Using EUCOMM Conditional-Ready Embryonic Stem Cells: A Case Study.

Overexpression of Cardiomyocyte α1A-Adrenergic Receptors Attenuates Postinfarct Remodeling by Inducing Angiogenesis Through Heterocellular Signaling.

Cardiac Regeneration Therapies - Targeting Neuregulin 1 Signalling.

Cardiomyocytes Replicate and their Numbers Increase in Young Hearts.

Heterologously-expressed and Liposome-reconstituted Human Transient Receptor Potential Melastatin 4 Channel (TRPM4) is a Functional Tetramer.

Identifying ligands at orphan GPCRs: current status using structure-based approaches.

Ablation of cardiac myosin binding protein-C disrupts the super-relaxed state of myosin in murine cardiomyocytes.

Targeted Doxorubicin Delivery to Brain Tumors via Minicells: Proof of Principle Using Dogs with Spontaneously Occurring Tumors as a Model.

Metalloprotease cleavage of the N terminus of the orphan G protein-coupled receptor GPR37L1 reduces its constitutive activity.

IGF-1 degradation by mouse mast cell protease 4 promotes cell death and adverse cardiac remodeling days after a myocardial infarction.

Gestational stress induces the unfolded protein response, resulting in heart defects.

Outcomes of patients with spontaneous coronary artery dissection.

Angiotensin type 2-receptor (AT2R) activation induces hypotension in apolipoprotein E-deficient mice by activating peroxisome proliferator-activated receptor-γ.

Pathophysiological Trends During Withdrawal of Life Support: Implications for Organ Donation After Circulatory Death.

Orphan receptor ligand discovery by pickpocketing pharmacological neighbors.

The Mystery and Enigma of Spontaneous Coronary Artery Dissection.

A Screening Approach to Identify Clinically Actionable Variants Causing Congenital Heart Disease in Exome Data.

Orphan receptor GPR37L1 contributes to the sexual dimorphism of central cardiovascular control.

Cardiac hypertrophy limits infarct expansion after myocardial infarction in mice.

Identification of clinically actionable variants from genome sequencing of families with congenital heart disease.

Association of the PHACTR1/EDN1 Genetic Locus With Spontaneous Coronary Artery Dissection.

The Australian Cardiovascular Alliance-Towards an Integrated Whole-of-Nation Strategy to Address Our Major Health Burden.

A vascular smooth muscle cell X-box binding protein 1 and transglutaminase 2 regulatory circuit limits neointimal hyperplasia.

Generation of VCCRIi001-A, a human induced pluripotent stem cell line, from a patient with spontaneous coronary artery dissection.

Redox activation of JNK2α2 mediates thyroid hormone-stimulated proliferation of neonatal murine cardiomyocytes.

Platelet-derived growth factor-AB improves scar mechanics and vascularity after myocardial infarction.

Spontaneous Coronary Artery Dissection and Fibromuscular Dysplasia: Vasculopathies With a Predilection for Women.

Essential Role for CD30-Transglutaminase 2 Axis in Memory Th1 and Th17 Cell Generation.

Pressure overload by suprarenal aortic constriction in mice leads to left ventricular hypertrophy without c-Kit expression in cardiomyocytes.

Spontaneous Coronary Artery Dissection: Insights on Rare Genetic Variation From Genome Sequencing.

The N-terminus of GPR37L1 is proteolytically processed by matrix metalloproteases.

DUSP5 expression in left ventricular cardiomyocytes of young hearts regulates thyroid hormone (T3)-induced proliferative ERK1/2 signaling.

Deletion of Orphan G Protein-Coupled Receptor GPR37L1 in Mice Alters Cardiovascular Homeostasis in a Sex-Specific Manner.

Adaptation to exercise-induced stress is not dependent on cardiomyocyte α-adrenergic receptors.

Retraction Note: Orphan receptor ligand discovery by pickpocketing pharmacological neighbors.

Cardiac Gq Receptors and Calcineurin Activation Are Not Required for the Hypertrophic Response to Mechanical Left Ventricular Pressure Overload.

Thyroid hormone plus dual-specificity phosphatase-5 siRNA increases the number of cardiac muscle cells and improves left ventricular contractile function in chronic doxorubicin-injured hearts.

Everolimus for the Prevention of Calcineurin-Inhibitor-Induced Left Ventricular Hypertrophy After Heart Transplantation (RADTAC Study).

The Ca-activated cation channel TRPM4 is a positive regulator of pressure overload-induced cardiac hypertrophy.

Involvement of GPR37L1 in murine blood pressure regulation and human cardiac disease pathophysiology.

Mechanism-Based Cardiac Regeneration Strategies in Mammals.

Vascular Stiffness in Aging and Disease.

Accuracy of vascular tortuosity measures using computational modelling.

Exploring the Genetic Architecture of Spontaneous Coronary Artery Dissection Using Whole-Genome Sequencing.

Remuscularization with triiodothyronine and β-blocker therapy reverses post-ischemic left ventricular dysfunction and adverse remodeling.

Cardiovascular Magnetic Resonance for Rejection Surveillance After Cardiac Transplantation.

Adverse events after spontaneous coronary artery dissection.

Standardised method for cardiomyocyte isolation and purification from individual murine neonatal, infant, and adult hearts.