Wei Kong

Department of Physiology and Pathophysiology, Peking University

Research Area

Biology

Biography

Wei Kong has not added Biography.
If you are Wei Kong and would like to personalize this page please email our Author Liaison for assistance.

JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2022

Other Publications

Article	Year
[Extracellular matrix, matrix-degrading proteases and vascular calcification]. Sheng li ke xue jin zhan [Progress in physiology]\| PubMed ID: 18819486	2008
Regulatory role of thioredoxin in homocysteine-induced monocyte chemoattractant protein-1 secretion in monocytes/macrophages. FEBS letters\| PubMed ID: 18976655	2008
ADAMTS-7 mediates vascular smooth muscle cell migration and neointima formation in balloon-injured rat arteries. Circulation research\| PubMed ID: 19168437	2009
Regulatory T cells ameliorate hyperhomocysteinaemia-accelerated atherosclerosis in apoE-/- mice. Cardiovascular research\| PubMed ID: 19502284	2009
Homocysteine promotes vascular smooth muscle cell migration by induction of the adipokine resistin. American journal of physiology. Cell physiology\| PubMed ID: 19828833	2009
Cartilage oligomeric matrix protein maintains the contractile phenotype of vascular smooth muscle cells by interacting with alpha(7)beta(1) integrin. Circulation research\| PubMed ID: 20019333	2010
A novel mechanism of γ/δ T-lymphocyte and endothelial activation by shear stress: the role of ecto-ATP synthase β chain. Circulation research\| PubMed ID: 21193741	2011
Cartilage oligomeric matrix protein inhibits vascular smooth muscle calcification by interacting with bone morphogenetic protein-2. Circulation research\| PubMed ID: 21350216	2011
Mitochondrial reactive oxygen species promote p65 nuclear translocation mediating high-phosphate-induced vascular calcification in vitro and in vivo. Kidney international\| PubMed ID: 21368742	2011
[The role of adventitia in atherosclerosis]. Sheng li ke xue jin zhan [Progress in physiology]\| PubMed ID: 21416976	2010
[Diabetic cardiomyopathy]. Sheng li ke xue jin zhan [Progress in physiology]\| PubMed ID: 21417012	2010
Homocysteine upregulates soluble epoxide hydrolase in vascular endothelium in vitro and in vivo. Circulation research\| PubMed ID: 22354938	2012
Small-molecule inhibition of human immunodeficiency virus type 1 replication by targeting the interaction between Vif and ElonginC. Journal of virology\| PubMed ID: 22379088	2012
Activation of nuclear factor-kappa B accelerates vascular calcification by inhibiting ankylosis protein homolog expression. Kidney international\| PubMed ID: 22437419	2012
Fenofibrate enhances the in vitro differentiation of foxp3(+) regulatory T cells in mice. PPAR research\| PubMed ID: 22536210	2012
Fenofibrate inhibited the differentiation of T helper 17 cells in vitro. PPAR research\| PubMed ID: 22792085	2012
Hyperhomocysteinemia exaggerates adventitial inflammation and angiotensin II-induced abdominal aortic aneurysm in mice. Circulation research\| PubMed ID: 22912384	2012
Upregulation of a disintegrin and metalloproteinase with thrombospondin motifs-7 by miR-29 repression mediates vascular smooth muscle calcification. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 22995515	2012
CTLA4-IgG ameliorates homocysteine-accelerated atherosclerosis by inhibiting T-cell overactivation in apoE(-/-) mice. Cardiovascular research\| PubMed ID: 23118130	2013
Phosphate-induced autophagy counteracts vascular calcification by reducing matrix vesicle release. Kidney international\| PubMed ID: 23364520	2013
Hyperhomocysteinemia promotes insulin resistance by inducing endoplasmic reticulum stress in adipose tissue. The Journal of biological chemistry\| PubMed ID: 23417716	2013
Deficiency of cartilage oligomeric matrix protein causes dilated cardiomyopathy. Basic research in cardiology\| PubMed ID: 23917519	2013
Intermedin inhibits macrophage foam-cell formation via tristetraprolin-mediated decay of CD36 mRNA. Cardiovascular research\| PubMed ID: 24253523	2014
Hyperhomocysteinemia and methylenetetrahydrofolate reductase polymorphism in cervical artery dissection: a meta-analysis. Cerebrovascular diseases (Basel, Switzerland)\| PubMed ID: 24903192	2014
Disruption of TGF-β signaling in smooth muscle cell prevents elastase-induced abdominal aortic aneurysm. Biochemical and biophysical research communications\| PubMed ID: 25450370	2014
Disruption of TGF-β signaling in smooth muscle cell prevents flow-induced vascular remodeling. Biochemical and biophysical research communications\| PubMed ID: 25451249	2014
Macrophage inflammasome mediates hyperhomocysteinemia-aggravated abdominal aortic aneurysm. Journal of molecular and cellular cardiology\| PubMed ID: 25680906	2015
ADAMTS-7 Inhibits Re-Endothelialization of Injured Arteries and Promotes Vascular Remodeling Via Cleavage of Thrombospondin-1. Circulation\| PubMed ID: 25712208	2015
ADAMTS-7 promotes vascular smooth muscle cells proliferation in vitro and in vivo. Science China. Life sciences\| PubMed ID: 25921940	2015
Cartilage oligomeric matrix protein is a natural inhibitor of thrombin. Blood\| PubMed ID: 26045608	2015
Mammalian target of rapamycin signaling inhibition ameliorates vascular calcification via Klotho upregulation. Kidney international\| PubMed ID: 26061549	2015
Predicting Abdominal Aortic Aneurysm Target Genes by Level-2 Protein-Protein Interaction. PloS one\| PubMed ID: 26496478	2015
Microsomal Prostaglandin E Synthase-1-Derived PGE2 Inhibits Vascular Smooth Muscle Cell Calcification. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 26543101	2016
A disintegrin and metalloproteinase with thrombospondin motif 1 (ADAMTS1) expression increases in acute aortic dissection. Science China. Life sciences\| PubMed ID: 26563155	2016
Hyaluronan Is Crucial for Stem Cell Differentiation into Smooth Muscle Lineage. Stem cells (Dayton, Ohio)\| PubMed ID: 26867148	2016
Shift of Macrophage Phenotype Due to Cartilage Oligomeric Matrix Protein Deficiency Drives Atherosclerotic Calcification. Circulation research\| PubMed ID: 27151399	2016
ECM-mimetic heparin glycosamioglycan-functionalized surface favors constructing functional vascular smooth muscle tissue in vitro. Colloids and surfaces. B, Biointerfaces\| PubMed ID: 27351139	2016
Cartilage oligomeric matrix protein prevents vascular aging and vascular smooth muscle cells senescence. Biochemical and biophysical research communications\| PubMed ID: 27498005	2016
The E3 ubiquitin ligase c-Cbl mediates integrin β1 ubiquitination during dilated cardiomyopathy. Biochemical and biophysical research communications\| PubMed ID: 27693578	2016
[The mechanisms of medial vascular calcification]. Sheng li xue bao : [Acta physiologica Sinica]\| PubMed ID: 27778024	2016
ADAM17: A Molecular Switch to Control TNFR2 During Atherogenesis In Vivo. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 28122773	2017
Cartilage Oligomeric Matrix Protein: Matricellular and Matricrine Signaling in Cardiovascular Homeostasis and Disease. Current vascular pharmacology\| PubMed ID: 28155614	2017
Cardioprotection of ischemic preconditioning in rats involves upregulating adiponectin. Journal of molecular endocrinology\| PubMed ID: 28219936	2017
Transdifferentiated Human Vascular Smooth Muscle Cells are a New Potential Cell Source for Endothelial Regeneration. Scientific reports\| PubMed ID: 28717251	2017
CYLD Deubiquitinates Nicotinamide Adenine Dinucleotide Phosphate Oxidase 4 Contributing to Adventitial Remodeling. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 28751569	2017
Basic and Translational Vascular Research in China: Past, Present, and Future. Circulation research\| PubMed ID: 28775012	2017
Hyperhomocysteinemia and Vascular Injury: The Advance of Mechanisms and Drug Targets. British journal of pharmacology\| PubMed ID: 28836260	2017
Hypoxia decrease expression of cartilage oligomeric matrix protein to promote phenotype switching of pulmonary arterial smooth muscle cells. The international journal of biochemistry & cell biology\| PubMed ID: 28860005	2017
Unspliced XBP1 Confers VSMC Homeostasis and Prevents Aortic Aneurysm Formation via FoxO4 Interaction. Circulation research\| PubMed ID: 29089350	2017
Small infrarenal aortic diameter associated with lower-extremity peripheral artery disease in Chinese hypertensive adults. Scientific reports\| PubMed ID: 29109408	2017
Matrix stiffness determines the phenotype of vascular smooth muscle cell in vitro and in vivo: Role of DNA methyltransferase 1. Biomaterials\| PubMed ID: 29182961	2018
Homocysteine directly interacts and activates the angiotensin II type I receptor to aggravate vascular injury. Nature communications\| PubMed ID: 29296021	2018
Extracellular matrix remodeling and cardiac fibrosis. Matrix biology : journal of the International Society for Matrix Biology\| PubMed ID: 29371055	2018
Gq activity- and β-arrestin-1 scaffolding-mediated ADGRG2/CFTR coupling are required for male fertility. eLife\| PubMed ID: 29393851	2018
Novel Adipokine, FAM19A5, Inhibits Neointima Formation After Injury Through Sphingosine-1-Phosphate Receptor 2. Circulation\| PubMed ID: 29453251	2018
Adipocyte-derived Lysophosphatidylcholine Activates Adipocyte and Adipose Tissue Macrophage Nod-Like Receptor Protein 3 Inflammasomes Mediating Homocysteine-Induced Insulin Resistance. EBioMedicine\| PubMed ID: 29735414	2018
Renal injury in Seipin-deficient lipodystrophic mice and its reversal by adipose tissue transplantation or leptin administration alone: adipose tissue-kidney crosstalk. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 29738274	2018
The Increased Endogenous Sulfur Dioxide Acts as a Compensatory Mechanism for the Downregulated Endogenous Hydrogen Sulfide Pathway in the Endothelial Cell Inflammation. Frontiers in immunology\| PubMed ID: 29760703	2018
Deficiency of FAM3D (Family With Sequence Similarity 3, Member D), A Novel Chemokine, Attenuates Neutrophil Recruitment and Ameliorates Abdominal Aortic Aneurysm Development. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 29853563	2018
COMP-prohibitin 2 interaction maintains mitochondrial homeostasis and controls smooth muscle cell identity. Cell death & disease\| PubMed ID: 29867124	2018
Histone Variant H2A.Z Is Required for the Maintenance of Smooth Muscle Cell Identity as Revealed by Single-Cell Transcriptomics. Circulation\| PubMed ID: 29871976	2018
Cartilage oligomeric matrix protein is a novel notch ligand driving embryonic stem cell differentiation towards the smooth muscle lineage. Journal of molecular and cellular cardiology\| PubMed ID: 29981303	2018
Naringenin inhibits N-nitro-L-arginine methyl ester-induced hypertensive left ventricular hypertrophy by decreasing angiotensin-converting enzyme 1 expression. Experimental and therapeutic medicine\| PubMed ID: 30112041	2018
Postnatal deficiency of ADAMTS1 ameliorates thoracic aortic aneurysm and dissection in mice. Experimental physiology\| PubMed ID: 30191627	2018
Rapamycin prevents thoracic aortic aneurysm and dissection in mice. Journal of vascular surgery\| PubMed ID: 30253896	2019
DNA methyltransferase 1 and Krüppel-like factor 4 axis regulates macrophage inflammation and atherosclerosis. Journal of molecular and cellular cardiology\| PubMed ID: 30659837	2019
Gpihbp1 deficiency accelerates atherosclerosis and plaque instability in diabetic Ldlr mice. Atherosclerosis\| PubMed ID: 30721842	2019
Rapamycin attenuates a murine model of thoracic aortic aneurysm by downregulating the miR-126-3p mediated activation of MAPK/ERK signalling pathway. Biochemical and biophysical research communications\| PubMed ID: 30904162	2019
The -methyladenosine (mA)-forming enzyme METTL3 facilitates M1 macrophage polarization through the methylation of mRNA. American journal of physiology. Cell physiology\| PubMed ID: 31365297	2019
Ablation of gut microbiota alleviates obesity-induced hepatic steatosis and glucose intolerance by modulating bile acid metabolism in hamsters. Acta pharmaceutica Sinica. B\| PubMed ID: 31384531	2019
Macrophage metabolic reprogramming aggravates aortic dissection through the HIF1α-ADAM17 pathway. EBioMedicine\| PubMed ID: 31640947	2019
Endogenous hydrogen sulfide sulfhydrates IKKβ at cysteine 179 to control pulmonary artery endothelial cell inflammation. Clinical science (London, England : 1979)\| PubMed ID: 31654061	2019
Adipocyte Hypoxia-Inducible Factor 2α Suppresses Atherosclerosis by Promoting Adipose Ceramide Catabolism. Cell metabolism\| PubMed ID: 31668872	2019
Genetically Encoded Fluorescent Amino Acid for Monitoring Protein Interactions through FRET. Analytical chemistry\| PubMed ID: 31670502	2019
Kindlin-2 suppresses transcription factor GATA4 through interaction with SUV39H1 to attenuate hypertrophy. Cell death & disease\| PubMed ID: 31767831	2019
Endothelial tight junctions and their regulatory signaling pathways in vascular homeostasis and disease. Cellular signalling\| PubMed ID: 31770579	2020
B cell-derived anti-beta 2 glycoprotein I antibody contributes to hyperhomocysteinaemia-aggravated abdominal aortic aneurysm. Cardiovascular research\| PubMed ID: 31782769	2020
PSMP/MSMP promotes hepatic fibrosis through CCR2 and represents a novel therapeutic target. Journal of hepatology\| PubMed ID: 31813573	2020
L-Cystathionine Protects against Homocysteine-Induced Mitochondria-Dependent Apoptosis of Vascular Endothelial Cells. Oxidative medicine and cellular longevity\| PubMed ID: 31885769	2019
Hypermethylation of mitochondrial DNA in vascular smooth muscle cells impairs cell contractility. Cell death & disease\| PubMed ID: 31959742	2020
Macrophage-derived sulfur dioxide is a novel inflammation regulator. Biochemical and biophysical research communications\| PubMed ID: 32057367	2020
Cellular signaling in Abdominal Aortic Aneurysm. Cellular signalling\| PubMed ID: 32088371	2020
Runx2 (Runt-Related Transcription Factor 2)-Mediated Microcalcification Is a Novel Pathological Characteristic and Potential Mediator of Abdominal Aortic Aneurysm. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 32212850	2020
Elevated serum cartilage oligomeric matrix protein and the metalloproteinase-ADAMTS7 levels are associated with vascular calcification in maintenance hemodialysis patients. Seminars in dialysis\| PubMed ID: 32441044	2020
Vascular Extracellular Matrix Remodeling and Hypertension. Antioxidants & redox signaling\| PubMed ID: 32460598	2021
Kindlin-2 deficiency induces fatal intestinal obstruction in mice. Theranostics\| PubMed ID: 32483447	2020
Extracellular matrix dynamics in vascular remodeling. American journal of physiology. Cell physiology\| PubMed ID: 32579472	2020
NSun2 regulates aneurysm formation by promoting autotaxin expression and T cell recruitment. Cellular and molecular life sciences : CMLS\| PubMed ID: 32734582	2021
DeSiphering receptor core-induced and ligand-dependent conformational changes in arrestin via genetic encoded trimethylsilyl H-NMR probe. Nature communications\| PubMed ID: 32978402	2020
Cartilage oligomeric matrix protein fine-tunes disturbed flow-induced endothelial activation and atherogenesis. Matrix biology : journal of the International Society for Matrix Biology\| PubMed ID: 33068727	2021
Naringin Alleviates Atherosclerosis in ApoE Mice by Regulating Cholesterol Metabolism Involved in Gut Microbiota Remodeling. Journal of agricultural and food chemistry\| PubMed ID: 33107729	2020
FAM3D is essential for colon homeostasis and host defense against inflammation associated carcinogenesis. Nature communications\| PubMed ID: 33219235	2020
Post-translational Modifications of IκBα: The State of the Art. Frontiers in cell and developmental biology\| PubMed ID: 33224945	2020
Cartilage oligomeric matrix protein is an endogenous β-arrestin-2-selective allosteric modulator of AT1 receptor counteracting vascular injury. Cell research\| PubMed ID: 33510386	2021
Endogenous SO-dependent Smad3 redox modification controls vascular remodeling. Redox biology\| PubMed ID: 33647858	2021
X-box binding protein 1-mediated COL4A1s secretion regulates communication between vascular smooth muscle and stem/progenitor cells. The Journal of biological chemistry\| PubMed ID: 33722606	2021
LOXL4 Abrogation Does Not Exaggerate Angiotensin II-Induced Thoracic or Abdominal Aortic Aneurysm in Mice. Genes\| PubMed ID: 33807332	2021
Blocking FcγRIIB in Smooth Muscle Cells Reduces Hypertension. Circulation research\| PubMed ID: 33980031	2021
Identification of COL3A1 variants associated with sporadic thoracic aortic dissection: a case-control study. Frontiers of medicine\| PubMed ID: 34047934	2021
Whole-Mount Kidney Clearing and Visualization Reveal Renal Sympathetic Hyperinnervation in Heart Failure Mice. Frontiers in physiology\| PubMed ID: 34305650	2021
Nidogen-2 Maintains the Contractile Phenotype of Vascular Smooth Muscle Cells and Prevents Neointima Formation via Bridging Jagged1-Notch3 Signaling. Circulation\| PubMed ID: 34315224	2021
Pan-HDAC (Histone Deacetylase) Inhibitors Increase Susceptibility of Thoracic Aortic Aneurysm and Dissection in Mice. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 34525846	2021
The binding of autotaxin to integrins mediates hyperhomocysteinemia-potentiated platelet activation and thrombosis in mice and humans. Blood advances\| PubMed ID: 34559203	2022
Association between Lipid Levels and Risk for Different Types of Aneurysms: A Mendelian Randomization Study. Journal of personalized medicine\| PubMed ID: 34834523	2021
COMP (Cartilage Oligomeric Matrix Protein), a Novel PIEZO1 Regulator That Controls Blood Pressure. Hypertension (Dallas, Tex. : 1979)\| PubMed ID: 34983194	2022
Vascular smooth muscle cell-derived hydrogen sulfide promotes atherosclerotic plaque stability via TFEB (transcription factor EB)-mediated autophagy. Autophagy\| PubMed ID: 35090378	2022
Single-cell RNA sequencing reveals B cell-T cell interactions in vascular adventitia of hyperhomocysteinemia-accelerated atherosclerosis. Protein & cell\| PubMed ID: 35175542	2022
Targeting macrophage TFEB-14-3-3 epsilon Interface by naringenin inhibits abdominal aortic aneurysm. Cell discovery\| PubMed ID: 35228523	2022
Investigating the inverse association between glycaemia and abdominal aortic dilatation in a large Chinese hypertensive population: a cross-sectional study. Annals of translational medicine\| PubMed ID: 35530958	2022
Endogenous Hydrogen Sulfide Persulfidates Caspase-3 at Cysteine 163 to Inhibit Doxorubicin-Induced Cardiomyocyte Apoptosis. Oxidative medicine and cellular longevity\| PubMed ID: 35571249	2022
Matricellular proteins: Potential biomarkers and mechanistic factors in aortic aneurysms. Journal of molecular and cellular cardiology\| PubMed ID: 35576729	2022
MicroRNA-Disease Network Analysis Repurposes Methotrexate for the Treatment of Abdominal Aortic Aneurysm in Mice. Genomics, proteomics & bioinformatics\| PubMed ID: 36030000	2022
PHB2 Maintains the Contractile Phenotype of VSMCs by Counteracting PKM2 Splicing. Circulation research\| PubMed ID: 36200440	2022
Nidogen-2 is a Novel Endogenous Ligand of LGR4 to Inhibit Vascular Calcification. Circulation research\| PubMed ID: 36354004	2022