Wei Kong

[Extracellular matrix, matrix-degrading proteases and vascular calcification].

Regulatory role of thioredoxin in homocysteine-induced monocyte chemoattractant protein-1 secretion in monocytes/macrophages.

ADAMTS-7 mediates vascular smooth muscle cell migration and neointima formation in balloon-injured rat arteries.

Regulatory T cells ameliorate hyperhomocysteinaemia-accelerated atherosclerosis in apoE-/- mice.

Homocysteine promotes vascular smooth muscle cell migration by induction of the adipokine resistin.

Cartilage oligomeric matrix protein maintains the contractile phenotype of vascular smooth muscle cells by interacting with alpha(7)beta(1) integrin.

A novel mechanism of γ/δ T-lymphocyte and endothelial activation by shear stress: the role of ecto-ATP synthase β chain.

Cartilage oligomeric matrix protein inhibits vascular smooth muscle calcification by interacting with bone morphogenetic protein-2.

Mitochondrial reactive oxygen species promote p65 nuclear translocation mediating high-phosphate-induced vascular calcification in vitro and in vivo.

[The role of adventitia in atherosclerosis].

[Diabetic cardiomyopathy].

Homocysteine upregulates soluble epoxide hydrolase in vascular endothelium in vitro and in vivo.

Small-molecule inhibition of human immunodeficiency virus type 1 replication by targeting the interaction between Vif and ElonginC.

Activation of nuclear factor-kappa B accelerates vascular calcification by inhibiting ankylosis protein homolog expression.

Fenofibrate enhances the in vitro differentiation of foxp3(+) regulatory T cells in mice.

Fenofibrate inhibited the differentiation of T helper 17 cells in vitro.

Hyperhomocysteinemia exaggerates adventitial inflammation and angiotensin II-induced abdominal aortic aneurysm in mice.

Upregulation of a disintegrin and metalloproteinase with thrombospondin motifs-7 by miR-29 repression mediates vascular smooth muscle calcification.

CTLA4-IgG ameliorates homocysteine-accelerated atherosclerosis by inhibiting T-cell overactivation in apoE(-/-) mice.

Phosphate-induced autophagy counteracts vascular calcification by reducing matrix vesicle release.

Hyperhomocysteinemia promotes insulin resistance by inducing endoplasmic reticulum stress in adipose tissue.

Deficiency of cartilage oligomeric matrix protein causes dilated cardiomyopathy.

Intermedin inhibits macrophage foam-cell formation via tristetraprolin-mediated decay of CD36 mRNA.

Hyperhomocysteinemia and methylenetetrahydrofolate reductase polymorphism in cervical artery dissection: a meta-analysis.

Disruption of TGF-β signaling in smooth muscle cell prevents elastase-induced abdominal aortic aneurysm.

Disruption of TGF-β signaling in smooth muscle cell prevents flow-induced vascular remodeling.

Macrophage inflammasome mediates hyperhomocysteinemia-aggravated abdominal aortic aneurysm.

ADAMTS-7 Inhibits Re-Endothelialization of Injured Arteries and Promotes Vascular Remodeling Via Cleavage of Thrombospondin-1.

ADAMTS-7 promotes vascular smooth muscle cells proliferation in vitro and in vivo.

Cartilage oligomeric matrix protein is a natural inhibitor of thrombin.

Mammalian target of rapamycin signaling inhibition ameliorates vascular calcification via Klotho upregulation.

Predicting Abdominal Aortic Aneurysm Target Genes by Level-2 Protein-Protein Interaction.

Microsomal Prostaglandin E Synthase-1-Derived PGE2 Inhibits Vascular Smooth Muscle Cell Calcification.

A disintegrin and metalloproteinase with thrombospondin motif 1 (ADAMTS1) expression increases in acute aortic dissection.

Hyaluronan Is Crucial for Stem Cell Differentiation into Smooth Muscle Lineage.

Shift of Macrophage Phenotype Due to Cartilage Oligomeric Matrix Protein Deficiency Drives Atherosclerotic Calcification.

ECM-mimetic heparin glycosamioglycan-functionalized surface favors constructing functional vascular smooth muscle tissue in vitro.

Cartilage oligomeric matrix protein prevents vascular aging and vascular smooth muscle cells senescence.

The E3 ubiquitin ligase c-Cbl mediates integrin β1 ubiquitination during dilated cardiomyopathy.

[The mechanisms of medial vascular calcification].

ADAM17: A Molecular Switch to Control TNFR2 During Atherogenesis In Vivo.

Cartilage Oligomeric Matrix Protein: Matricellular and Matricrine Signaling in Cardiovascular Homeostasis and Disease.

Cardioprotection of ischemic preconditioning in rats involves upregulating adiponectin.

Transdifferentiated Human Vascular Smooth Muscle Cells are a New Potential Cell Source for Endothelial Regeneration.

CYLD Deubiquitinates Nicotinamide Adenine Dinucleotide Phosphate Oxidase 4 Contributing to Adventitial Remodeling.

Basic and Translational Vascular Research in China: Past, Present, and Future.

Hyperhomocysteinemia and Vascular Injury: The Advance of Mechanisms and Drug Targets.

Hypoxia decrease expression of cartilage oligomeric matrix protein to promote phenotype switching of pulmonary arterial smooth muscle cells.

Unspliced XBP1 Confers VSMC Homeostasis and Prevents Aortic Aneurysm Formation via FoxO4 Interaction.

Small infrarenal aortic diameter associated with lower-extremity peripheral artery disease in Chinese hypertensive adults.

Matrix stiffness determines the phenotype of vascular smooth muscle cell in vitro and in vivo: Role of DNA methyltransferase 1.

Homocysteine directly interacts and activates the angiotensin II type I receptor to aggravate vascular injury.

Extracellular matrix remodeling and cardiac fibrosis.

Gq activity- and β-arrestin-1 scaffolding-mediated ADGRG2/CFTR coupling are required for male fertility.

Novel Adipokine, FAM19A5, Inhibits Neointima Formation After Injury Through Sphingosine-1-Phosphate Receptor 2.

Adipocyte-derived Lysophosphatidylcholine Activates Adipocyte and Adipose Tissue Macrophage Nod-Like Receptor Protein 3 Inflammasomes Mediating Homocysteine-Induced Insulin Resistance.

Renal injury in Seipin-deficient lipodystrophic mice and its reversal by adipose tissue transplantation or leptin administration alone: adipose tissue-kidney crosstalk.

The Increased Endogenous Sulfur Dioxide Acts as a Compensatory Mechanism for the Downregulated Endogenous Hydrogen Sulfide Pathway in the Endothelial Cell Inflammation.

Deficiency of FAM3D (Family With Sequence Similarity 3, Member D), A Novel Chemokine, Attenuates Neutrophil Recruitment and Ameliorates Abdominal Aortic Aneurysm Development.

COMP-prohibitin 2 interaction maintains mitochondrial homeostasis and controls smooth muscle cell identity.

Histone Variant H2A.Z Is Required for the Maintenance of Smooth Muscle Cell Identity as Revealed by Single-Cell Transcriptomics.

Cartilage oligomeric matrix protein is a novel notch ligand driving embryonic stem cell differentiation towards the smooth muscle lineage.

Naringenin inhibits N-nitro-L-arginine methyl ester-induced hypertensive left ventricular hypertrophy by decreasing angiotensin-converting enzyme 1 expression.

Postnatal deficiency of ADAMTS1 ameliorates thoracic aortic aneurysm and dissection in mice.

Rapamycin prevents thoracic aortic aneurysm and dissection in mice.

DNA methyltransferase 1 and Krüppel-like factor 4 axis regulates macrophage inflammation and atherosclerosis.

Gpihbp1 deficiency accelerates atherosclerosis and plaque instability in diabetic Ldlr mice.

Rapamycin attenuates a murine model of thoracic aortic aneurysm by downregulating the miR-126-3p mediated activation of MAPK/ERK signalling pathway.

The -methyladenosine (mA)-forming enzyme METTL3 facilitates M1 macrophage polarization through the methylation of mRNA.

Ablation of gut microbiota alleviates obesity-induced hepatic steatosis and glucose intolerance by modulating bile acid metabolism in hamsters.

Macrophage metabolic reprogramming aggravates aortic dissection through the HIF1α-ADAM17 pathway.

Endogenous hydrogen sulfide sulfhydrates IKKβ at cysteine 179 to control pulmonary artery endothelial cell inflammation.

Adipocyte Hypoxia-Inducible Factor 2α Suppresses Atherosclerosis by Promoting Adipose Ceramide Catabolism.

Genetically Encoded Fluorescent Amino Acid for Monitoring Protein Interactions through FRET.

Kindlin-2 suppresses transcription factor GATA4 through interaction with SUV39H1 to attenuate hypertrophy.

Endothelial tight junctions and their regulatory signaling pathways in vascular homeostasis and disease.

B cell-derived anti-beta 2 glycoprotein I antibody contributes to hyperhomocysteinaemia-aggravated abdominal aortic aneurysm.

PSMP/MSMP promotes hepatic fibrosis through CCR2 and represents a novel therapeutic target.

L-Cystathionine Protects against Homocysteine-Induced Mitochondria-Dependent Apoptosis of Vascular Endothelial Cells.

Hypermethylation of mitochondrial DNA in vascular smooth muscle cells impairs cell contractility.

Macrophage-derived sulfur dioxide is a novel inflammation regulator.

Cellular signaling in Abdominal Aortic Aneurysm.

Runx2 (Runt-Related Transcription Factor 2)-Mediated Microcalcification Is a Novel Pathological Characteristic and Potential Mediator of Abdominal Aortic Aneurysm.

Elevated serum cartilage oligomeric matrix protein and the metalloproteinase-ADAMTS7 levels are associated with vascular calcification in maintenance hemodialysis patients.

Vascular Extracellular Matrix Remodeling and Hypertension.

Kindlin-2 deficiency induces fatal intestinal obstruction in mice.

Extracellular matrix dynamics in vascular remodeling.

NSun2 regulates aneurysm formation by promoting autotaxin expression and T cell recruitment.

DeSiphering receptor core-induced and ligand-dependent conformational changes in arrestin via genetic encoded trimethylsilyl H-NMR probe.

Cartilage oligomeric matrix protein fine-tunes disturbed flow-induced endothelial activation and atherogenesis.

Naringin Alleviates Atherosclerosis in ApoE Mice by Regulating Cholesterol Metabolism Involved in Gut Microbiota Remodeling.

FAM3D is essential for colon homeostasis and host defense against inflammation associated carcinogenesis.

Post-translational Modifications of IκBα: The State of the Art.

Cartilage oligomeric matrix protein is an endogenous β-arrestin-2-selective allosteric modulator of AT1 receptor counteracting vascular injury.

Endogenous SO-dependent Smad3 redox modification controls vascular remodeling.

X-box binding protein 1-mediated COL4A1s secretion regulates communication between vascular smooth muscle and stem/progenitor cells.

LOXL4 Abrogation Does Not Exaggerate Angiotensin II-Induced Thoracic or Abdominal Aortic Aneurysm in Mice.

Blocking FcγRIIB in Smooth Muscle Cells Reduces Hypertension.

Identification of COL3A1 variants associated with sporadic thoracic aortic dissection: a case-control study.

Whole-Mount Kidney Clearing and Visualization Reveal Renal Sympathetic Hyperinnervation in Heart Failure Mice.

Nidogen-2 Maintains the Contractile Phenotype of Vascular Smooth Muscle Cells and Prevents Neointima Formation via Bridging Jagged1-Notch3 Signaling.

Pan-HDAC (Histone Deacetylase) Inhibitors Increase Susceptibility of Thoracic Aortic Aneurysm and Dissection in Mice.

The binding of autotaxin to integrins mediates hyperhomocysteinemia-potentiated platelet activation and thrombosis in mice and humans.

Association between Lipid Levels and Risk for Different Types of Aneurysms: A Mendelian Randomization Study.

COMP (Cartilage Oligomeric Matrix Protein), a Novel PIEZO1 Regulator That Controls Blood Pressure.

Vascular smooth muscle cell-derived hydrogen sulfide promotes atherosclerotic plaque stability via TFEB (transcription factor EB)-mediated autophagy.

Single-cell RNA sequencing reveals B cell-T cell interactions in vascular adventitia of hyperhomocysteinemia-accelerated atherosclerosis.

Targeting macrophage TFEB-14-3-3 epsilon Interface by naringenin inhibits abdominal aortic aneurysm.

Investigating the inverse association between glycaemia and abdominal aortic dilatation in a large Chinese hypertensive population: a cross-sectional study.

Endogenous Hydrogen Sulfide Persulfidates Caspase-3 at Cysteine 163 to Inhibit Doxorubicin-Induced Cardiomyocyte Apoptosis.

Matricellular proteins: Potential biomarkers and mechanistic factors in aortic aneurysms.

MicroRNA-Disease Network Analysis Repurposes Methotrexate for the Treatment of Abdominal Aortic Aneurysm in Mice.

PHB2 Maintains the Contractile Phenotype of VSMCs by Counteracting PKM2 Splicing.

Nidogen-2 is a Novel Endogenous Ligand of LGR4 to Inhibit Vascular Calcification.