Center for Oncological Research (CORE),
Integrated Personalized & Precision Oncology Network (IPPON),
Center for Oncological Research (CORE), Integrated Personalized & Precision Oncology Network (IPPON)
Filip Lardon has not added Biography.
If you are Filip Lardon and would like to personalize this page please email our Author Liaison for assistance.
Messenger RNA electroporation of human monocytes, followed by rapid in vitro differentiation, leads to highly stimulatory antigen-loaded mature dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) Aug, 2002 | Pubmed ID: 12165485
Comparison of the sulforhodamine B assay and the clonogenic assay for in vitro chemoradiation studies.
Cancer chemotherapy and pharmacology Mar, 2003 | Pubmed ID: 12655440
Cell cycle effect of gemcitabine and its role in the radiosensitizing mechanism in vitro.
International journal of radiation oncology, biology, physics Nov, 2003 | Pubmed ID: 14575839
Can cervical cancer screening be stopped at 50? The prevalence of HPV in elderly women.
International journal of cancer Jan, 2004 | Pubmed ID: 14639612
The prevalence of the human papillomavirus in cervix and vagina in low-risk and high-risk populations.
Scandinavian journal of infectious diseases , 2004 | Pubmed ID: 15307568
Combined modality therapy of gemcitabine and radiation.
The oncologist Jan, 2005 | Pubmed ID: 15632251
Unraveling the mechanism of radiosensitization by gemcitabine: the role of TP53.
Radiation research Nov, 2005 | Pubmed ID: 16238441
Combined Pap and HPV testing in primary screening for cervical abnormalities: should HPV detection be delayed until age 35?
European journal of cancer (Oxford, England : 1990) Nov, 2005 | Pubmed ID: 16242316
Cell cycle effects of vinflunine, the most recent promising Vinca alkaloid, and its interaction with radiation, in vitro.
Cancer chemotherapy and pharmacology Aug, 2006 | Pubmed ID: 16317558
The radiosensitising effect of difluorodeoxyuridine, a metabolite of gemcitabine, in vitro.
Cancer chemotherapy and pharmacology Aug, 2006 | Pubmed ID: 16331496
Comparison of three commonly used PCR-based techniques to analyze MSI status in sporadic colorectal cancer.
Journal of clinical laboratory analysis , 2006 | Pubmed ID: 16538640
The relation between deoxycytidine kinase activity and the radiosensitising effect of gemcitabine in eight different human tumour cell lines.
BMC cancer May, 2006 | Pubmed ID: 16734894
Review: implications of in vitro research on the effect of radiotherapy and chemotherapy under hypoxic conditions.
The oncologist Jun, 2007 | Pubmed ID: 17602059
Further mechanistic unravelling of the influence of the cell cycle effects on the radiosensitising mechanism of vinflunine, in vitro.
Cancer chemotherapy and pharmacology Jul, 2008 | Pubmed ID: 17899084
Detection of microsatellite instability in colorectal cancer using an alternative multiplex assay of quasi-monomorphic mononucleotide markers.
The Journal of molecular diagnostics : JMD Mar, 2008 | Pubmed ID: 18258928
Comparative study of the radiosensitizing and cell cycle effects of vinflunine and vinorelbine, in vitro.
BMC cancer Feb, 2008 | Pubmed ID: 18312675
Microsatellite instability in sporadic colon carcinomas has no independent prognostic value in a Belgian study population.
European journal of cancer (Oxford, England : 1990) Oct, 2008 | Pubmed ID: 18707864
Chemoradiation interactions under reduced oxygen conditions: Cellular characteristics of an in vitro model.
Cancer letters Dec, 2009 | Pubmed ID: 19540039
Everything you always wanted to know about HPV (but could not ask your doctor).
Patient education and counseling Oct, 2010 | Pubmed ID: 20056371
Counting clonogenic assays from normoxic and anoxic irradiation experiments manually or by using densitometric software.
Physics in medicine and biology Apr, 2010 | Pubmed ID: 20208097
Detection of HPV and the role of p16INK4A overexpression as a surrogate marker for the presence of functional HPV oncoprotein E7 in colorectal cancer.
BMC cancer Mar, 2010 | Pubmed ID: 20346145
Tumor infiltrating lymphocytes: an intriguing player in the survival of colorectal cancer patients.
BMC immunology Apr, 2010 | Pubmed ID: 20385003
A review of the most promising biomarkers in colorectal cancer: one step closer to targeted therapy.
The oncologist , 2010 | Pubmed ID: 20584808
In vitro study on the schedule-dependency of the interaction between pemetrexed, gemcitabine and irradiation in non-small cell lung cancer and head and neck cancer cells.
BMC cancer Aug, 2010 | Pubmed ID: 20723210
Role of cell cycle perturbations in the combination therapy of chemotherapeutic agents and radiation.
Future oncology (London, England) Sep, 2010 | Pubmed ID: 20919831
The presence of Y chromosomal deoxyribonucleic acid in the female vaginal swab: possible implications for human papillomavirus testing.
Cancer epidemiology Feb, 2011 | Pubmed ID: 21095173
Retention of the in vitro radiosensitizing potential of gemcitabine under anoxic conditions, in p53 wild-type and p53-deficient non-small-cell lung carcinoma cells.
International journal of radiation oncology, biology, physics Jun, 2011 | Pubmed ID: 21377279
Immune Cells in Colorectal Cancer: Prognostic Relevance and Role of MSI.
Cancer microenvironment : official journal of the International Cancer Microenvironment Society Dec, 2011 | Pubmed ID: 21618031
Expression analysis on archival material: comparison of 5 commercially available RNA isolation kits for FFPE material.
Diagnostic molecular pathology : the American journal of surgical pathology, part B Dec, 2011 | Pubmed ID: 22089347
Tumor cells and tumor-associated macrophages: secreted proteins as potential targets for therapy.
Clinical & developmental immunology , 2011 | Pubmed ID: 22162712
Probiotics enhance the clearance of human papillomavirus-related cervical lesions: a prospective controlled pilot study.
European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) Jan, 2013 | Pubmed ID: 22706167
The interaction between ER and NFκB in resistance to endocrine therapy.
Breast cancer research : BCR , 2012 | Pubmed ID: 22963717
The intriguing interplay between therapies targeting the epidermal growth factor receptor, the hypoxic microenvironment and hypoxia-inducible factors.
Current pharmaceutical design , 2013 | Pubmed ID: 22973959
Comparative analysis of dynamic cell viability, migration and invasion assessments by novel real-time technology and classic endpoint assays.
PloS one , 2012 | Pubmed ID: 23094027
Expression analysis on archival material revisited: isolation and quantification of RNA extracted from FFPE samples.
Diagnostic molecular pathology : the American journal of surgical pathology, part B Mar, 2013 | Pubmed ID: 23370428
Anti-epidermal growth factor receptor therapy in head and neck squamous cell carcinoma: focus on potential molecular mechanisms of drug resistance.
The oncologist , 2013 | Pubmed ID: 23821327
Krüppel-like factors in cancer progression: three fingers on the steering wheel.
Oncotarget Jan, 2014 | Pubmed ID: 24429391
Pharmacological levels of Withaferin A (Withania somnifera) trigger clinically relevant anticancer effects specific to triple negative breast cancer cells.
PloS one , 2014 | Pubmed ID: 24498382
Study assessing the quality of quantification of estrogen receptor protein expression by immunohistochemistry and gene expression in breast cancer.
Pathology research international , 2014 | Pubmed ID: 24734208
Synthesis and in vivo preclinical evaluation of an (18)F labeled uPA inhibitor as a potential PET imaging agent.
Nuclear medicine and biology Jul, 2014 | Pubmed ID: 24768145
Mutation analysis of genes in the EGFR pathway in Head and Neck cancer patients: implications for anti-EGFR treatment response.
BMC research notes , 2014 | Pubmed ID: 24899223
Phase II multicenter clinical trial of pulmonary metastasectomy and isolated lung perfusion with melphalan in patients with resectable lung metastases.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer Oct, 2014 | Pubmed ID: 25105436
The radiosensitising effect of gemcitabine and its main metabolite dFdU under low oxygen conditions is in vitro not dependent on functional HIF-1 protein.
BMC cancer , 2014 | Pubmed ID: 25128202
Overcoming cetuximab resistance in HNSCC: the role of AURKB and DUSP proteins.
Cancer letters Nov, 2014 | Pubmed ID: 25192874
Expression profiling of migrated and invaded breast cancer cells predicts early metastatic relapse and reveals Krüppel-like factor 9 as a potential suppressor of invasive growth in breast cancer.
Oncoscience , 2014 | Pubmed ID: 25593984
Decreased expression of ABAT and STC2 hallmarks ER-positive inflammatory breast cancer and endocrine therapy resistance in advanced disease.
Molecular oncology Jun, 2015 | Pubmed ID: 25771305
The hypoxic tumor microenvironment and drug resistance against EGFR inhibitors: preclinical study in cetuximab-sensitive head and neck squamous cell carcinoma cell lines.
BMC research notes , 2015 | Pubmed ID: 26032726
The MDM2-inhibitor Nutlin-3 synergizes with cisplatin to induce p53 dependent tumor cell apoptosis in non-small cell lung cancer.
Oncotarget Sep, 2015 | Pubmed ID: 26125230
Establishment and characterization of cetuximab resistant head and neck squamous cell carcinoma cell lines: focus on the contribution of the AP-1 transcription factor.
American journal of cancer research , 2015 | Pubmed ID: 26269754
Immune Checkpoint Modulation in Colorectal Cancer: What's New and What to Expect.
Journal of immunology research , 2015 | Pubmed ID: 26605342
In vitro and in vivo investigations on the antitumour activity of Chelidonium majus.
Phytomedicine : international journal of phytotherapy and phytopharmacology Dec, 2015 | Pubmed ID: 26626193
TP53 and MDM2 genetic alterations in non-small cell lung cancer: Evaluating their prognostic and predictive value.
Critical reviews in oncology/hematology Mar, 2016 | Pubmed ID: 26689115
APR-246 (PRIMA-1(MET)) strongly synergizes with AZD2281 (olaparib) induced PARP inhibition to induce apoptosis in non-small cell lung cancer cell lines.
Cancer letters Jun, 2016 | Pubmed ID: 26975633
Efficacy Screening of Gloriosa Superba Extracts in a Murine Pancreatic Cancer Model Using (18)F-FDG PET/CT for Monitoring Treatment Response.
Cancer biotherapy & radiopharmaceuticals Apr, 2016 | Pubmed ID: 27093343
Primary skeletal muscle myoblasts from chronic heart failure patients exhibit loss of anti-inflammatory and proliferative activity.
BMC cardiovascular disorders May, 2016 | Pubmed ID: 27228977
A Comparison of Cell-Free DNA Isolation Kits: Isolation and Quantification of Cell-Free DNA in Plasma.
The Journal of molecular diagnostics : JMD Jan, 2017 | Pubmed ID: 27865784
Better to be alone than in bad company: The antagonistic effect of cisplatin and crizotinib combination therapy in non-small cell lung cancer.
World journal of clinical oncology Dec, 2016 | Pubmed ID: 28008383
Deep sequencing of the TP53 gene reveals a potential risk allele for non-small cell lung cancer and supports the negative prognostic value of TP53 variants.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine Feb, 2017 | Pubmed ID: 28240049
Towards Prognostic Profiling of Non-Small Cell Lung Cancer: New Perspectives on the Relevance of Polo-Like Kinase 1 Expression, the Mutation Status and Hypoxia.
Journal of Cancer , 2017 | Pubmed ID: 28638459
SNP309 and SNP285 Act as Negative Prognostic Markers for Non-small Cell Lung Cancer Adenocarcinoma Patients.
Journal of Cancer , 2017 | Pubmed ID: 28819417
Dual Targeting of Epidermal Growth Factor Receptor and HER3 by MEHD7945A as Monotherapy or in Combination with Cisplatin Partially Overcomes Cetuximab Resistance in Head and Neck Squamous Cell Carcinoma Cell Lines.
Cancer biotherapy & radiopharmaceuticals Sep, 2017 | Pubmed ID: 28910149
Interleukin-15 stimulates natural killer cell-mediated killing of both human pancreatic cancer and stellate cells.
Oncotarget Aug, 2017 | Pubmed ID: 28915646
Preclinical data on the combination of cisplatin and anti-CD70 therapy in non-small cell lung cancer as an excellent match in the era of combination therapy.
Oncotarget Sep, 2017 | Pubmed ID: 29088768
Poly(I:C) primes primary human glioblastoma cells for an immune response invigorated by PD-L1 blockade.
Oncoimmunology , 2018 | Pubmed ID: 29399410
Simultaneous targeting of EGFR, HER2, and HER4 by afatinib overcomes intrinsic and acquired cetuximab resistance in head and neck squamous cell carcinoma cell lines.
Molecular oncology Jun, 2018 | Pubmed ID: 29603584
Hypoxia-Induced Cisplatin Resistance in Non-Small Cell Lung Cancer Cells Is Mediated by HIF-1α and Mutant p53 and Can Be Overcome by Induction of Oxidative Stress.
Cancers Apr, 2018 | Pubmed ID: 29690507
Monitoring EGFR TKI resistance in real time using ddPCR-based liquid biopsy: a case report.
Journal of clinical pathology Aug, 2018 | Pubmed ID: 29853531
Unveiling a CD70-positive subset of cancer-associated fibroblasts marked by pro-migratory activity and thriving regulatory T cell accumulation.
Oncoimmunology , 2018 | Pubmed ID: 29900042
Overcoming Intrinsic and Acquired Cetuximab Resistance in RAS Wild-Type Colorectal Cancer: An In Vitro Study on the Expression of HER Receptors and the Potential of Afatinib.
Cancers Jan, 2019 | Pubmed ID: 30650638
RANK/RANKL signaling inhibition may improve the effectiveness of checkpoint blockade in cancer treatment.
Critical reviews in oncology/hematology Jan, 2019 | Pubmed ID: 30661662
In vitro study of the Polo-like kinase 1 inhibitor volasertib in non-small-cell lung cancer reveals a role for the tumor suppressor p53.
Molecular oncology May, 2019 | Pubmed ID: 30859681
Circulating Cell-Free DNA and RNA Analysis as Liquid Biopsy: Optimal Centrifugation Protocol.
Cancers Mar, 2019 | Pubmed ID: 30935089
Multicenter Phase II Clinical Trial of Isolated Lung Perfusion in Patients With Lung Metastases.
The Annals of thoracic surgery Jul, 2019 | Pubmed ID: 30951699
RANK-RANKL Signaling in Cancer of the Uterine Cervix: A Review.
International journal of molecular sciences May, 2019 | Pubmed ID: 31052546
Decrease in phospho-PRAS40 plays a role in the synergy between erlotinib and crizotinib in an EGFR and cMET wild-type squamous non-small cell lung cancer cell line.
Biochemical pharmacology Aug, 2019 | Pubmed ID: 31078602
The Benefit of Reactivating p53 under MAPK Inhibition on the Efficacy of Radiotherapy in Melanoma.
Cancers Aug, 2019 | Pubmed ID: 31374895
The potential and controversy of targeting STAT family members in cancer.
Seminars in cancer biology Feb, 2020 | Pubmed ID: 31605750
Cold Atmospheric Plasma-Treated PBS Eliminates Immunosuppressive Pancreatic Stellate Cells and Induces Immunogenic Cell Death of Pancreatic Cancer Cells.
Cancers Oct, 2019 | Pubmed ID: 31635070
Radiosensitization of Non-Small Cell Lung Cancer Cells by the Plk1 Inhibitor Volasertib Is Dependent on the p53 Status.
Cancers Nov, 2019 | Pubmed ID: 31795121
The Role of c-Met as a Biomarker and Player in Innate and Acquired Resistance in Non-Small-Cell Lung Cancer: Two New Mutations Warrant Further Studies.
Molecules (Basel, Switzerland) Dec, 2019 | Pubmed ID: 31817278
Specialized Blood Collection Tubes for Liquid Biopsy: Improving the Pre-analytical Conditions.
Molecular diagnosis & therapy Feb, 2020 | Pubmed ID: 31838654
Cetuximab-induced natural killer cell cytotoxicity in head and neck squamous cell carcinoma cell lines: investigation of the role of cetuximab sensitivity and HPV status.
British journal of cancer Sep, 2020 | Pubmed ID: 32541873
Novel combination immunotherapy for pancreatic cancer: potent anti-tumor effects with CD40 agonist and interleukin-15 treatment.
Clinical & translational immunology , 2020 | Pubmed ID: 32821382
Targeting the PD-1 Axis with Pembrolizumab for Recurrent or Metastatic Cancer of the Uterine Cervix: A Brief Update.
International journal of molecular sciences Feb, 2021 | Pubmed ID: 33670397
Cancer-Associated Fibroblasts as a Common Orchestrator of Therapy Resistance in Lung and Pancreatic Cancer.
Cancers Feb, 2021 | Pubmed ID: 33673405
Recent insights in the PI3K/Akt pathway as a promising therapeutic target in combination with EGFR-targeting agents to treat head and neck squamous cell carcinoma.
Medicinal research reviews Jan, 2022 | Pubmed ID: 33928670
A systematic review on poly(I:C) and poly-ICLC in glioblastoma: adjuvants coordinating the unlocking of immunotherapy.
Journal of experimental & clinical cancer research : CR Jun, 2021 | Pubmed ID: 34172082
Evaluation of Cytologic Sample Preparations for Compatibility With Nucleic Acid Analysis.
American journal of clinical pathology Feb, 2022 | Pubmed ID: 34542583
The Right Partner in Crime: Unlocking the Potential of the Anti-EGFR Antibody Cetuximab Combination With Natural Killer Cell Chartering Immunotherapeutic Strategies.
Frontiers in immunology , 2021 | Pubmed ID: 34557197
The Role of Akt in Acquired Cetuximab Resistant Head and Neck Squamous Cell Carcinoma: An Study on a Novel Combination Strategy.
Frontiers in oncology , 2021 | Pubmed ID: 34568028
Auranofin and Cold Atmospheric Plasma Synergize to Trigger Distinct Cell Death Mechanisms and Immunogenic Responses in Glioblastoma.
Cells Oct, 2021 | Pubmed ID: 34831159
Targeting hedgehog signaling in pancreatic ductal adenocarcinoma.
Pharmacology & therapeutics Aug, 2022 | Pubmed ID: 34999181
NTRK Gene Fusion Detection in a Pan-Cancer Setting Using the Idylla GeneFusion Assay.
The Journal of molecular diagnostics : JMD Jul, 2022 | Pubmed ID: 35550184
Characterization of acquired nutlin-3 resistant non-small cell lung cancer cells.
Cancer drug resistance (Alhambra, Calif.) , 2021 | Pubmed ID: 35582010
Expression of SARS-CoV-2-Related Surface Proteins in Non-Small-Cell Lung Cancer Patients and the Influence of Standard of Care Therapy.
Cancers Aug, 2022 | Pubmed ID: 36077610
Prognostic implications of cellular senescence in resected non-small cell lung cancer.
Translational lung cancer research Aug, 2022 | Pubmed ID: 36090630
The effect of local non-thermal plasma therapy on the cancer-immunity cycle in a melanoma mouse model.
Bioengineering & translational medicine Sep, 2022 | Pubmed ID: 36176603
The prognostic impact of the immune signature in head and neck squamous cell carcinoma.
Frontiers in immunology , 2022 | Pubmed ID: 36268020
OrBITS: label-free and time-lapse monitoring of patient derived organoids for advanced drug screening.
Cellular oncology (Dordrecht) Dec, 2022 | Pubmed ID: 36508089
Maxim Le Compte1,
Edgar Cardenas De La Hoz2,
Sofía Peeters1,
Evelien Smits1,
Filip Lardon1,
Geert Roeyen1,3,
Steve Vanlanduit2,
Hans Prenen1,4,
Marc Peeters1,4,
Abraham Lin1,5,
Christophe Deben1
1Center for Oncological Research (CORE), Integrated Personalized & Precision Oncology Network (IPPON), University of Antwerp,
2Industrial Vision Lab, University of Antwerp,
3Department of Hepatobiliary Transplantation and Endocrine Surgery, University Hospital Antwerp (UZA),
4Department of Oncology, University Hospital Antwerp (UZA),
5Plasma Lab for Applications in Sustainability and Medicine ANTwerp (PLASMANT), University of Antwerp
ABOUT JoVE
Copyright © 2024 MyJoVE Corporation. All rights reserved