Filip Lardon

Messenger RNA electroporation of human monocytes, followed by rapid in vitro differentiation, leads to highly stimulatory antigen-loaded mature dendritic cells.

Comparison of the sulforhodamine B assay and the clonogenic assay for in vitro chemoradiation studies.

Cell cycle effect of gemcitabine and its role in the radiosensitizing mechanism in vitro.

Can cervical cancer screening be stopped at 50? The prevalence of HPV in elderly women.

The prevalence of the human papillomavirus in cervix and vagina in low-risk and high-risk populations.

Combined modality therapy of gemcitabine and radiation.

Unraveling the mechanism of radiosensitization by gemcitabine: the role of TP53.

Combined Pap and HPV testing in primary screening for cervical abnormalities: should HPV detection be delayed until age 35?

Cell cycle effects of vinflunine, the most recent promising Vinca alkaloid, and its interaction with radiation, in vitro.

The radiosensitising effect of difluorodeoxyuridine, a metabolite of gemcitabine, in vitro.

Comparison of three commonly used PCR-based techniques to analyze MSI status in sporadic colorectal cancer.

The relation between deoxycytidine kinase activity and the radiosensitising effect of gemcitabine in eight different human tumour cell lines.

Review: implications of in vitro research on the effect of radiotherapy and chemotherapy under hypoxic conditions.

Further mechanistic unravelling of the influence of the cell cycle effects on the radiosensitising mechanism of vinflunine, in vitro.

Detection of microsatellite instability in colorectal cancer using an alternative multiplex assay of quasi-monomorphic mononucleotide markers.

Comparative study of the radiosensitizing and cell cycle effects of vinflunine and vinorelbine, in vitro.

Microsatellite instability in sporadic colon carcinomas has no independent prognostic value in a Belgian study population.

Chemoradiation interactions under reduced oxygen conditions: Cellular characteristics of an in vitro model.

Everything you always wanted to know about HPV (but could not ask your doctor).

Counting clonogenic assays from normoxic and anoxic irradiation experiments manually or by using densitometric software.

Detection of HPV and the role of p16INK4A overexpression as a surrogate marker for the presence of functional HPV oncoprotein E7 in colorectal cancer.

Tumor infiltrating lymphocytes: an intriguing player in the survival of colorectal cancer patients.

A review of the most promising biomarkers in colorectal cancer: one step closer to targeted therapy.

In vitro study on the schedule-dependency of the interaction between pemetrexed, gemcitabine and irradiation in non-small cell lung cancer and head and neck cancer cells.

Role of cell cycle perturbations in the combination therapy of chemotherapeutic agents and radiation.

The presence of Y chromosomal deoxyribonucleic acid in the female vaginal swab: possible implications for human papillomavirus testing.

Retention of the in vitro radiosensitizing potential of gemcitabine under anoxic conditions, in p53 wild-type and p53-deficient non-small-cell lung carcinoma cells.

Immune Cells in Colorectal Cancer: Prognostic Relevance and Role of MSI.

Expression analysis on archival material: comparison of 5 commercially available RNA isolation kits for FFPE material.

Tumor cells and tumor-associated macrophages: secreted proteins as potential targets for therapy.

Probiotics enhance the clearance of human papillomavirus-related cervical lesions: a prospective controlled pilot study.

The interaction between ER and NFκB in resistance to endocrine therapy.

The intriguing interplay between therapies targeting the epidermal growth factor receptor, the hypoxic microenvironment and hypoxia-inducible factors.

Comparative analysis of dynamic cell viability, migration and invasion assessments by novel real-time technology and classic endpoint assays.

Expression analysis on archival material revisited: isolation and quantification of RNA extracted from FFPE samples.

Anti-epidermal growth factor receptor therapy in head and neck squamous cell carcinoma: focus on potential molecular mechanisms of drug resistance.

Krüppel-like factors in cancer progression: three fingers on the steering wheel.

Pharmacological levels of Withaferin A (Withania somnifera) trigger clinically relevant anticancer effects specific to triple negative breast cancer cells.

Study assessing the quality of quantification of estrogen receptor protein expression by immunohistochemistry and gene expression in breast cancer.

Synthesis and in vivo preclinical evaluation of an (18)F labeled uPA inhibitor as a potential PET imaging agent.

Mutation analysis of genes in the EGFR pathway in Head and Neck cancer patients: implications for anti-EGFR treatment response.

Phase II multicenter clinical trial of pulmonary metastasectomy and isolated lung perfusion with melphalan in patients with resectable lung metastases.

The radiosensitising effect of gemcitabine and its main metabolite dFdU under low oxygen conditions is in vitro not dependent on functional HIF-1 protein.

Overcoming cetuximab resistance in HNSCC: the role of AURKB and DUSP proteins.

Expression profiling of migrated and invaded breast cancer cells predicts early metastatic relapse and reveals Krüppel-like factor 9 as a potential suppressor of invasive growth in breast cancer.

Decreased expression of ABAT and STC2 hallmarks ER-positive inflammatory breast cancer and endocrine therapy resistance in advanced disease.

The hypoxic tumor microenvironment and drug resistance against EGFR inhibitors: preclinical study in cetuximab-sensitive head and neck squamous cell carcinoma cell lines.

The MDM2-inhibitor Nutlin-3 synergizes with cisplatin to induce p53 dependent tumor cell apoptosis in non-small cell lung cancer.

Establishment and characterization of cetuximab resistant head and neck squamous cell carcinoma cell lines: focus on the contribution of the AP-1 transcription factor.

Immune Checkpoint Modulation in Colorectal Cancer: What's New and What to Expect.

In vitro and in vivo investigations on the antitumour activity of Chelidonium majus.

TP53 and MDM2 genetic alterations in non-small cell lung cancer: Evaluating their prognostic and predictive value.

APR-246 (PRIMA-1(MET)) strongly synergizes with AZD2281 (olaparib) induced PARP inhibition to induce apoptosis in non-small cell lung cancer cell lines.

Efficacy Screening of Gloriosa Superba Extracts in a Murine Pancreatic Cancer Model Using (18)F-FDG PET/CT for Monitoring Treatment Response.

Primary skeletal muscle myoblasts from chronic heart failure patients exhibit loss of anti-inflammatory and proliferative activity.

A Comparison of Cell-Free DNA Isolation Kits: Isolation and Quantification of Cell-Free DNA in Plasma.

Better to be alone than in bad company: The antagonistic effect of cisplatin and crizotinib combination therapy in non-small cell lung cancer.

Deep sequencing of the TP53 gene reveals a potential risk allele for non-small cell lung cancer and supports the negative prognostic value of TP53 variants.

Towards Prognostic Profiling of Non-Small Cell Lung Cancer: New Perspectives on the Relevance of Polo-Like Kinase 1 Expression, the Mutation Status and Hypoxia.

SNP309 and SNP285 Act as Negative Prognostic Markers for Non-small Cell Lung Cancer Adenocarcinoma Patients.

Dual Targeting of Epidermal Growth Factor Receptor and HER3 by MEHD7945A as Monotherapy or in Combination with Cisplatin Partially Overcomes Cetuximab Resistance in Head and Neck Squamous Cell Carcinoma Cell Lines.

Interleukin-15 stimulates natural killer cell-mediated killing of both human pancreatic cancer and stellate cells.

Preclinical data on the combination of cisplatin and anti-CD70 therapy in non-small cell lung cancer as an excellent match in the era of combination therapy.

Poly(I:C) primes primary human glioblastoma cells for an immune response invigorated by PD-L1 blockade.

Simultaneous targeting of EGFR, HER2, and HER4 by afatinib overcomes intrinsic and acquired cetuximab resistance in head and neck squamous cell carcinoma cell lines.

Hypoxia-Induced Cisplatin Resistance in Non-Small Cell Lung Cancer Cells Is Mediated by HIF-1α and Mutant p53 and Can Be Overcome by Induction of Oxidative Stress.

Monitoring EGFR TKI resistance in real time using ddPCR-based liquid biopsy: a case report.

Unveiling a CD70-positive subset of cancer-associated fibroblasts marked by pro-migratory activity and thriving regulatory T cell accumulation.

Overcoming Intrinsic and Acquired Cetuximab Resistance in RAS Wild-Type Colorectal Cancer: An In Vitro Study on the Expression of HER Receptors and the Potential of Afatinib.

RANK/RANKL signaling inhibition may improve the effectiveness of checkpoint blockade in cancer treatment.

In vitro study of the Polo-like kinase 1 inhibitor volasertib in non-small-cell lung cancer reveals a role for the tumor suppressor p53.

Circulating Cell-Free DNA and RNA Analysis as Liquid Biopsy: Optimal Centrifugation Protocol.

Multicenter Phase II Clinical Trial of Isolated Lung Perfusion in Patients With Lung Metastases.

RANK-RANKL Signaling in Cancer of the Uterine Cervix: A Review.

Decrease in phospho-PRAS40 plays a role in the synergy between erlotinib and crizotinib in an EGFR and cMET wild-type squamous non-small cell lung cancer cell line.

The Benefit of Reactivating p53 under MAPK Inhibition on the Efficacy of Radiotherapy in Melanoma.

The potential and controversy of targeting STAT family members in cancer.

Cold Atmospheric Plasma-Treated PBS Eliminates Immunosuppressive Pancreatic Stellate Cells and Induces Immunogenic Cell Death of Pancreatic Cancer Cells.

Radiosensitization of Non-Small Cell Lung Cancer Cells by the Plk1 Inhibitor Volasertib Is Dependent on the p53 Status.

The Role of c-Met as a Biomarker and Player in Innate and Acquired Resistance in Non-Small-Cell Lung Cancer: Two New Mutations Warrant Further Studies.

Specialized Blood Collection Tubes for Liquid Biopsy: Improving the Pre-analytical Conditions.

Cetuximab-induced natural killer cell cytotoxicity in head and neck squamous cell carcinoma cell lines: investigation of the role of cetuximab sensitivity and HPV status.

Novel combination immunotherapy for pancreatic cancer: potent anti-tumor effects with CD40 agonist and interleukin-15 treatment.

Targeting the PD-1 Axis with Pembrolizumab for Recurrent or Metastatic Cancer of the Uterine Cervix: A Brief Update.

Cancer-Associated Fibroblasts as a Common Orchestrator of Therapy Resistance in Lung and Pancreatic Cancer.

Recent insights in the PI3K/Akt pathway as a promising therapeutic target in combination with EGFR-targeting agents to treat head and neck squamous cell carcinoma.

A systematic review on poly(I:C) and poly-ICLC in glioblastoma: adjuvants coordinating the unlocking of immunotherapy.

Evaluation of Cytologic Sample Preparations for Compatibility With Nucleic Acid Analysis.

The Right Partner in Crime: Unlocking the Potential of the Anti-EGFR Antibody Cetuximab Combination With Natural Killer Cell Chartering Immunotherapeutic Strategies.

The Role of Akt in Acquired Cetuximab Resistant Head and Neck Squamous Cell Carcinoma: An Study on a Novel Combination Strategy.

Auranofin and Cold Atmospheric Plasma Synergize to Trigger Distinct Cell Death Mechanisms and Immunogenic Responses in Glioblastoma.

Targeting hedgehog signaling in pancreatic ductal adenocarcinoma.

NTRK Gene Fusion Detection in a Pan-Cancer Setting Using the Idylla GeneFusion Assay.

Characterization of acquired nutlin-3 resistant non-small cell lung cancer cells.

Expression of SARS-CoV-2-Related Surface Proteins in Non-Small-Cell Lung Cancer Patients and the Influence of Standard of Care Therapy.

Prognostic implications of cellular senescence in resected non-small cell lung cancer.

The effect of local non-thermal plasma therapy on the cancer-immunity cycle in a melanoma mouse model.

The prognostic impact of the immune signature in head and neck squamous cell carcinoma.

OrBITS: label-free and time-lapse monitoring of patient derived organoids for advanced drug screening.