Anne S. Ulrich

Synthesis of trifluoromethyl-substituted proline analogues as 19F NMR labels for peptides in the polyproline II conformation.

Conformation and membrane orientation of amphiphilic helical peptides by oriented circular dichroism.

Membrane thickening by the antimicrobial peptide PGLa.

Temperature-dependent transmembrane insertion of the amphiphilic peptide PGLa in lipid bilayers observed by solid state 19F NMR spectroscopy.

Synergistic transmembrane insertion of the heterodimeric PGLa/magainin 2 complex studied by solid-state NMR.

Orientation and dynamics of peptides in membranes calculated from 2H-NMR data.

Influence of whole-body dynamics on 15N PISEMA NMR spectra of membrane proteins: a theoretical analysis.

Using a sterically restrictive amino acid as a 19F NMR label to monitor and to control peptide aggregation in membranes.

Structure analysis of the membrane protein TatC(d) from the Tat system of B. subtilis by circular dichroism.

Calculation of fluorine chemical shift tensors for the interpretation of oriented (19)F-NMR spectra of gramicidin A in membranes.

Chemical labeling strategy with (R)- and (S)-trifluoromethylalanine for solid state 19F NMR analysis of peptaibols in membranes.

Dynamic transitions of membrane-active peptides.

The conserved Cys76 plays a crucial role for the conformation of reduced glutathione peroxidase-type tryparedoxin peroxidase.

Damage of the bacterial cell envelope by antimicrobial peptides gramicidin S and PGLa as revealed by transmission and scanning electron microscopy.

19F NMR analysis of the antimicrobial peptide PGLa bound to native cell membranes from bacterial protoplasts and human erythrocytes.

Short cationic antimicrobial peptides interact with ATP.

Structural role of the conserved cysteines in the dimerization of the viral transmembrane oncoprotein E5.

Membrane alignment of the pore-forming component TatA(d) of the twin-arginine translocase from Bacillus subtilis resolved by solid-state NMR spectroscopy.

Fluorescence of phytochrome adducts with synthetic locked chromophores.

Using the peptide BP100 as a cell-penetrating tool for the chemical engineering of actin filaments within living plant cells.

Irregular structure of the HIV fusion peptide in membranes demonstrated by solid-state NMR and MD simulations.

Special issue on membrane-active peptides.

A kinked antimicrobial peptide from Bombina maxima. II. Behavior in phospholipid bilayers.

Bilayer-mediated clustering and functional interaction of MscL channels.

Solid-state (19)F-NMR of peptides in native membranes.

Electrochemical insertion of lithium in mechanochemically synthesized Zn2SnO4.

Antimicrobial and cell-penetrating peptides induce lipid vesicle fusion by folding and aggregation.

Structure-activity analysis of the dermcidin-derived peptide DCD-1L, an anionic antimicrobial peptide present in human sweat.

Magnetically oriented dodecylphosphocholine bicelles for solid-state NMR structure analysis.

Hydrophobic mismatch of mobile transmembrane helices: Merging theory and experiments.

A novel dendrimeric peptide with antimicrobial properties: structure-function analysis of SB056.

Alignment of druglike compounds in lipid bilayers analyzed by solid-state (19)F-NMR and molecular dynamics, based on dipolar couplings of adjacent CF3 groups.

Self-assembly of flexible β-strands into immobile amyloid-like β-sheets in membranes as revealed by solid-state 19F NMR.

Comparative analysis of the orientation of transmembrane peptides using solid-state (2)H- and (15)N-NMR: mobility matters.

Hydrophobic matching controls the tilt and stability of the dimeric platelet-derived growth factor receptor (PDGFR) β transmembrane segment.

Rapid calculation of protein chemical shifts using bond polarization theory and its application to protein structure refinement.

Antimicrobial Peptides can Enhance the Risk of Persistent Infections.

Reorientation and dimerization of the membrane-bound antimicrobial peptide PGLa from microsecond all-atom MD simulations.

Structure analysis of the membrane-bound PhoD signal peptide of the Tat translocase shows an N-terminal amphiphilic helix.

Incorporation of cis- and trans-4,5-difluoromethanoprolines into polypeptides.

A peptidic unconjugated GRP78/BiP ligand modulates the unfolded protein response and induces prostate cancer cell death.

Peptide-lipid interactions of the stress-response peptide TisB that induces bacterial persistence.

Multilayered core-shell structure of polyol-stabilized calcium fluoride nanoparticles characterized by NMR.

Resemblance of electrospun collagen nanofibers to their native structure.

Folding and self-assembly of the TatA translocation pore based on a charge zipper mechanism.

Synergistic insertion of antimicrobial magainin-family peptides in membranes depends on the lipid spontaneous curvature.

Canonical azimuthal rotations and flanking residues constrain the orientation of transmembrane helices.

Solid State NMR Structure Analysis of the Antimicrobial Peptide Gramicidin S in Lipid Membranes: Concentration-Dependent Re-alignment and Self-Assembly as a β-Barrel.

Stereochemical effects on the aggregation and biological properties of the fibril-forming peptide [KIGAKI]3 in membranes.

Transformation of the matrix structure of shrimp shells during bacterial deproteination and demineralization.

Transient potential gradients and impedance measures of tethered bilayer lipid membranes: pore-forming peptide insertion and the effect of electroporation.

Controlling biological activity with light: diarylethene-containing cyclic peptidomimetics.

Structure of the membrane anchor of pestivirus glycoprotein E(rns), a long tilted amphipathic helix.

(19)F NMR screening of unrelated antimicrobial peptides shows that membrane interactions are largely governed by lipids.

How reliable are molecular dynamics simulations of membrane active antimicrobial peptides?

3D hydrophobic moment vectors as a tool to characterize the surface polarity of amphiphilic peptides.

Transmembrane helix assembly and the role of salt bridges.

Structure analysis and conformational transitions of the cell penetrating peptide transportan 10 in the membrane-bound state.

Oriented circular dichroism analysis of chiral surface-anchored metal-organic frameworks grown by liquid-phase epitaxy and upon loading with chiral guest compounds.

Labile or stable: can homoleptic and heteroleptic PyrPHOS-copper complexes be processed from solution?

Control and role of pH in peptide-lipid interactions in oriented membrane samples.

Action of the multifunctional peptide BP100 on native biomembranes examined by solid-state NMR.

Enhanced amphiphilic profile of a short β-stranded peptide improves its antimicrobial activity.

γ-(S)-Trifluoromethyl proline: evaluation as a structural substitute of proline for solid state (19)F-NMR peptide studies.

AMPs and OMPs: Is the folding and bilayer insertion of β-stranded outer membrane proteins governed by the same biophysical principles as for α-helical antimicrobial peptides?

Crown ether helical peptides are preferentially inserted in lipid bilayers as a transmembrane ion channels.

Fermentation and Cost-Effective 13C/15N Labeling of the Nonribosomal Peptide Gramicidin S for Nuclear Magnetic Resonance Structure Analysis.

Hydrophobic mismatch demonstrated for membranolytic peptides, and their use as molecular rulers to measure bilayer thickness in native cells.

Influence of hydrophobic residues on the activity of the antimicrobial peptide magainin 2 and its synergy with PGLa.

Micelle-Triggered β-Hairpin to α-Helix Transition in a 14-Residue Peptide from a Choline-Binding Repeat of the Pneumococcal Autolysin LytA.

UV-CD12: synchrotron radiation circular dichroism beamline at ANKA.

Synergistic effect of membrane-active peptides polymyxin B and gramicidin S on multidrug-resistant strains and biofilms of Pseudomonas aeruginosa.

(19)F-Labeling of Peptides Revealing Long-Range NMR Distances in Fluid Membranes.

Hydrophobic Mismatch Drives the Interaction of E5 with the Transmembrane Segment of PDGF Receptor.

An antifungal protein from Ginkgo biloba binds actin and can trigger cell death.

Rational modification of a dendrimeric peptide with antimicrobial activity: consequences on membrane-binding and biological properties.

Oriented Circular Dichroism: A Method to Characterize Membrane-Active Peptides in Oriented Lipid Bilayers.

Extending the Hydrophobic Mismatch Concept to Amphiphilic Membranolytic Peptides.

Alanine scan and (2)H NMR analysis of the membrane-active peptide BP100 point to a distinct carpet mechanism of action.

Direct Photocontrol of Peptidomimetics: An Alternative to Oxygen-Dependent Photodynamic Cancer Therapy.

Homo- and heteromeric interaction strengths of the synergistic antimicrobial peptides PGLa and magainin 2 in membranes.

SYNTHETIC FOLDAMERS. Light flips a membrane-embedded helix.

Does a methionine-to-norleucine substitution in PGLa influence peptide-membrane interactions?

Membrane Thinning and Thickening Induced by Membrane-Active Amphipathic Peptides.

Therapeutic Potential of Gramicidin S in the Treatment of Root Canal Infections.

Design, Synthesis, and Application of an Optimized Monofluorinated Aliphatic Label for Peptide Studies by Solid-State F NMR Spectroscopy.

Delivering Structural Information on the Polar Face of Membrane-Active Peptides: F-NMR Labels with a Cationic Side Chain.

H-NMR and MD Simulations Reveal Membrane-Bound Conformation of Magainin 2 and Its Synergy with PGLa.

Challenge Integrity: The Cell-Penetrating Peptide BP100 Interferes with the Auxin-Actin Oscillator.

Orientation and Location of the Cyclotide Kalata B1 in Lipid Bilayers Revealed by Solid-State NMR.

Antibiotic gold: tethering of antimicrobial peptides to gold nanoparticles maintains conformational flexibility of peptides and improves trypsin susceptibility.

Influence of the Length and Charge on the Activity of α-Helical Amphipathic Antimicrobial Peptides.

Antimicrobial peptide gramicidin S is accumulated in granules of producer cells for storage of bacterial phosphagens.

Membrane permeation of arginine-rich cell-penetrating peptides independent of transmembrane potential as a function of lipid composition and membrane fluidity.

Diphytanoyl lipids as model systems for studying membrane-active peptides.

Loosening of Lipid Packing Promotes Oligoarginine Entry into Cells.

Conformational Plasticity of the Cell-Penetrating Peptide SAP As Revealed by Solid-State F-NMR and Circular Dichroism Spectroscopies.

Structural Behavior of the Peptaibol Harzianin HK VI in a DMPC Bilayer: Insights from MD Simulations.

Membrane Association Landscape of Myelin Basic Protein Portrays Formation of the Myelin Major Dense Line.

Structure analysis of the membrane-bound dermcidin-derived peptide SSL-25 from human sweat.

Lactam-Stapled Cell-Penetrating Peptides: Cell Uptake and Membrane Binding Properties.

Flexibility vs rigidity of amphipathic peptide conjugates when interacting with lipid bilayers.

Molecular mechanism of synergy between the antimicrobial peptides PGLa and magainin 2.

Scaling the Amphiphilic Character and Antimicrobial Activity of Gramicidin S by Dihydroxylation or Ketal Formation.

New insights into the influence of monofluorination on dimyristoylphosphatidylcholine membrane properties: A solid-state NMR study.

"Force-from-lipids" gating of mechanosensitive channels modulated by PUFAs.

Orthogonal F-Labeling for Solid-State NMR Spectroscopy Reveals the Conformation and Orientation of Short Peptaibols in Membranes.

Roles of Amphipathicity and Hydrophobicity in the Micelle-Driven Structural Switch of a 14-mer Peptide Core from a Choline-Binding Repeat.

Efficiently Photocontrollable or Not? Biological Activity of Photoisomerizable Diarylethenes.

Transmembrane Polyproline Helix.

Helix Fraying and Lipid-Dependent Structure of a Short Amphipathic Membrane-Bound Peptide Revealed by Solid-State NMR.

Protein ORIGAMI: A program for the creation of 3D paper models of folded peptides.

Best of Two Worlds? How MD Simulations of Amphiphilic Helical Peptides in Membranes Can Complement Data from Oriented Solid-State NMR.

Structure-Activity Relationships of Photoswitchable Diarylethene-Based β-Hairpin Peptides as Membranolytic Antimicrobial and Anticancer Agents.

Molecular structure and function of myelin protein P0 in membrane stacking.

Tetrameric Charge-Zipper Assembly of the TisB Peptide in Membranes-Computer Simulation and Experiment.

Biocompatibility of Amine-Functionalized Silica Nanoparticles: The Role of Surface Coverage.

Inhibition of Pseudomonas aeruginosa biofilm formation and expression of virulence genes by selective epimerization in the peptide Esculentin-1a(1-21)NH.

4-Aminophthalimide Amino Acids as Small and Environment-Sensitive Fluorescent Probes for Transmembrane Peptides.

Bilayer thickness determines the alignment of model polyproline helices in lipid membranes.

Supreme activity of gramicidin S against resistant, persistent and biofilm cells of staphylococci and enterococci.

Shape-Memory Effect by Sequential Coupling of Functions over Different Length Scales in an Architectured Hydrogel.

Monofluoroalkene-Isostere as a F NMR Label for the Peptide Backbone: Synthesis and Evaluation in Membrane-Bound PGLa and (KIGAKI).

Light-controllable dithienylethene-modified cyclic peptides: photoswitching the in vivo toxicity in zebrafish embryos.

Terminal charges modulate the pore forming activity of cationic amphipathic helices.

Chiral supramolecular architecture of stable transmembrane pores formed by an α-helical antibiotic peptide in the presence of lyso-lipids.

Enhancing the activity of membrane remodeling epsin-peptide by trimerization.

Diarylethene moiety as an enthalpy-entropy switch: photoisomerizable stapled peptides for modulating p53/MDM2 interaction.

Phosphate-dependent aggregation of [KL] peptides affects their membranolytic activity.

Structural and functional characterization of the pore-forming domain of pinholin S68.

Overlapping Properties of the Short Membrane-Active Peptide BP100 With (i) Polycationic TAT and (ii) α-helical Magainin Family Peptides.

Chiral Resolution of Spin-Crossover Active Iron(II) [2x2] Grid Complexes.

Order and disorder-An integrative structure of the full-length human growth hormone receptor.

Behavior of the Antibacterial Peptide Cyclo[RRRWFW], Explored Using a 3-Hydroxychromone-Derived Fluorescent Amino Acid.

Diarylethene-Based Photoswitchable Inhibitors of Serine Proteases.

Membrane-Mediated Activity of Local Anesthetics.

Membrane Interactions of Latarcins: Antimicrobial Peptides from Spider Venom.

Remarkably high solvatochromism in the circular dichroism spectra of the polyproline-II conformation: limitations or new opportunities?

Antibiotic Potential and Biophysical Characterization of Amphipathic β-Stranded [XZ] Peptides With Alternating Cationic and Hydrophobic Residues.

Probing and Manipulating the Lateral Pressure Profile in Lipid Bilayers Using Membrane-Active Peptides-A Solid-State F NMR Study.

Towards in vivo photomediated delivery of anticancer peptides: Insights from pharmacokinetic and -dynamic data.

Highly Fluorinated Peptide Probes with Enhanced In Vivo Stability for F-MRI.

Membranolytic Mechanism of Amphiphilic Antimicrobial β-Stranded [KL] Peptides.

Temperature-Dependent Re-alignment of the Short Multifunctional Peptide BP100 in Membranes Revealed by Solid-State NMR Spectroscopy and Molecular Dynamics Simulations.

Length matters: Functional flip of the short TatA transmembrane helix.

Structural Dissection of Epsin-1 N-Terminal Helical Peptide: The Role of Hydrophobic Residues in Modulating Membrane Curvature.

Key Role of Choline Head Groups in Large Unilamellar Phospholipid Vesicles for the Interaction with and Rupture by Silica Nanoparticles.