In Vitro and In Vivo Evaluation of Photocontrolled Biologically Active Compounds - Potential Drug Candidates for Cancer Photopharmacology
2.1K Views
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13:17 min
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September 29th, 2023
DOI :
September 29th, 2023
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Chapters in this video
0:00
Introduction
1:22
IC50 Evaluation for LMB002 ("ring-closed" and "ring-open" forms) Using 2D and 3D LLC Cell Cultures
3:06
2D Cell Culture Experiment—Adding the Compounds (Day 2)
4:14
2D Cell Culture Experiment—Staining and Imaging (Days 2–5)
4:45
3D Cell Culture Experiment
5:46
Determination of Photoswitching Efficiency in a Tissue Surrogate
7:46
In Vivo Anticancer Efficacy Determination
9:39
Representative Results
12:40
Conclusion
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