Key Laboratory of Medical Electrophysiology of Ministry of Education,
Collaborative Innovation Center for Prevention and Treatment of Cardiovascular Disease,
Institute of Cardiovascular Research,
Key Laboratory of Medical Electrophysiology of Ministry of Education, Collaborative Innovation Center for Prevention and Treatment of Cardiovascular Disease, Institute of Cardiovascular Research
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Pak1 is required to maintain ventricular Ca²⁺ homeostasis and electrophysiological stability through SERCA2a regulation in mice.
Circulation. Arrhythmia and electrophysiology Oct, 2014 | Pubmed ID: 25217043
Effect of sphingosine-1-phosphate on L-type calcium current and Ca(2+) transient in rat ventricular myocytes.
Molecular and cellular biochemistry Aug, 2016 | Pubmed ID: 27372350
Three-dimensional image reconstruction of distribution of Pnmt cell-derived cells in murine heart.
Scientific data Sep, 2017 | Pubmed ID: 28949324
Late sodium current associated cardiac electrophysiological and mechanical dysfunction.
Pflugers Archiv : European journal of physiology Mar, 2018 | Pubmed ID: 29127493
Modernized Classification of Cardiac Antiarrhythmic Drugs.
Circulation Oct, 2018 | Pubmed ID: 30354657
Biochemical studies of membrane fusion at the single-particle level.
Progress in lipid research Jan, 2019 | Pubmed ID: 30611882
Response by Lei et al to Letter Regarding Article, "Modernized Classification of Cardiac Antiarrhythmic Drugs".
Circulation Mar, 2019 | Pubmed ID: 30908105
Pnmt-Derived Cardiomyocytes: Anatomical Localization, Function and Future Perspectives.
Frontiers in physiology , 2019 | Pubmed ID: 31354504
A Protocol for Dual Calcium-Voltage Optical Mapping in Murine Sinoatrial Preparation With Optogenetic Pacing.
Frontiers in physiology , 2019 | Pubmed ID: 31456689
Cardiac arrhythmogenesis: a tale of two clocks?
Cardiovascular research Dec, 2020 | Pubmed ID: 31800017
Update on antiarrhythmic drug pharmacology.
Journal of cardiovascular electrophysiology Feb, 2020 | Pubmed ID: 31930579
A potent antiarrhythmic drug N-methyl berbamine extends the action potential through inhibiting both calcium and potassium currents.
Journal of pharmacological sciences Apr, 2020 | Pubmed ID: 31992491
Distinct roles of calmodulin and Ca/calmodulin-dependent protein kinase II in isopreterenol-induced cardiac hypertrophy.
Biochemical and biophysical research communications Jun, 2020 | Pubmed ID: 32303334
Generation of three iPSC lines (XACHi007-A, XACHi008-A, XACHi009-A) from a Chinese family with long QT syndrome type 5 with heterozygous c.226G>A (p.D76N) mutation in KCNE1gene.
Stem cell research May, 2020 | Pubmed ID: 32344329
Editorial: Optogenetics: An Emerging Approach in Cardiac Electrophysiology.
Frontiers in physiology , 2020 | Pubmed ID: 32411019
Generation of two induced pluripotent stem cell lines (XACHi0010-A, XACHi0011-A) from a Chinese family with combined oxidative phosphorylation deficiency carrying homozygous and heterozygous C1QBP-L275F mutation.
Stem cell research Jul, 2020 | Pubmed ID: 32707487
Novel cardiac cell subpopulations: Pnmt-derived cardiomyocytes.
Open biology Aug, 2020 | Pubmed ID: 32810421
Establishment of iPSC line from a Chinese infant (XACHi012-A) with Jervell and Lange-Nielsen syndrome carrying combined KCNQ1 frameshift c.431delC(p.I145Sfs*92) and nonsense c.1175G > A (p.W392X) variants and two iPSC lines from the parents (XACHi013-A, XACHi014-A).
Stem cell research May, 2021 | Pubmed ID: 34088017
Generation of induced pluripotent stem cells (iPSCs) from a Chinese infant (XACHi015-A) with type 2 Long QT syndrome carrying the heterozygous mutation c.1814C>T(p.P605L) in KCNH2.
Stem cell research Oct, 2021 | Pubmed ID: 34438161
Electrophysiological and Proarrhythmic Effects of Hydroxychloroquine Challenge in Guinea-Pig Hearts.
ACS pharmacology & translational science Oct, 2021 | Pubmed ID: 34661080
Ventricular SK2 upregulation following angiotensin II challenge: Modulation by p21-activated kinase-1.
Journal of molecular and cellular cardiology Mar, 2022 | Pubmed ID: 34774547
A Comparative Study of Systolic and Diastolic Mechanical Synchrony in Canine, Primate, and Healthy and Failing Human Hearts.
Frontiers in cardiovascular medicine , 2021 | Pubmed ID: 34778406
A dataset of dual calcium and voltage optical mapping in healthy and hypertrophied murine hearts.
Scientific data Dec, 2021 | Pubmed ID: 34916511
Ageing Increases Cardiac Electrical Remodelling in Rats and Mice via NOX4/ROS/CaMKII-Mediated Calcium Signalling.
Oxidative medicine and cellular longevity , 2022 | Pubmed ID: 35387264
Neuropilin-1 is a valuable biomarker for predicting response of advanced non-small cell lung cancer patients to hypofractionated radiotherapy and PD-1 blockade.
International immunopharmacology Aug, 2022 | Pubmed ID: 35468364
High-Resolution 3D Heart Models of Cardiomyocyte Subpopulations in Cleared Murine Heart.
Frontiers in physiology , 2022 | Pubmed ID: 35665220
Exploration of interaction property between nonylphenol and G protein-coupled receptor 30 based on molecular simulation and biological experiments.
Steroids Dec, 2022 | Pubmed ID: 36154832
Various Fractions of Alcoholic Extracts from Functionalized Antioxidation and Antiaging in D-Galactose-Induced Aging Mice.
Frontiers in bioscience (Landmark edition) Nov, 2022 | Pubmed ID: 36472113
Cardiac deficiency of P21-activated kinase 1 promotes atrial arrhythmogenesis in mice following adrenergic challenge.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences Jun, 2023 | Pubmed ID: 37122217
Generation of cardiomyocytes from human-induced pluripotent stem cells resembling atrial cells with ability to respond to adrenoceptor agonists.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences Jun, 2023 | Pubmed ID: 37122218
Phenome-wide association study and precision medicine of cardiovascular diseases in the post-COVID-19 era.
Acta pharmacologica Sinica Dec, 2023 | Pubmed ID: 37532784
Editorial: Cardiovascular remodeling.
Frontiers in pharmacology , 2023 | Pubmed ID: 37554980
The novel peptide athycaltide-1 attenuates Ang II-induced pathological myocardial hypertrophy by reducing ROS and inhibiting the activation of CaMKII and ERK1/2.
European journal of pharmacology Oct, 2023 | Pubmed ID: 37567457
Single-cell RNA sequencing of murine hearts for studying the development of the cardiac conduction system.
Scientific data Sep, 2023 | Pubmed ID: 37666871
Dbh catecholaminergic cardiomyocytes contribute to the structure and function of the cardiac conduction system in murine heart.
Nature communications Nov, 2023 | Pubmed ID: 38016975
Mechanosensitive channels TMEM63A and TMEM63B mediate lung inflation-induced surfactant secretion.
The Journal of clinical investigation Dec, 2023 | Pubmed ID: 38127458
Yangpeng Li*,1,2,
Jun Yang*,1,
Rui Zhang1,
Tangting Chen1,
Shiyu Zhang1,
Yuqing Zheng1,
Qiang Wen3,
Tao Li1,
Xiaoqiu Tan1,2,
Ming Lei1,4,
Xianhong Ou1
1Key Laboratory of Medical Electrophysiology of Ministry of Education, Collaborative Innovation Center for Prevention and Treatment of Cardiovascular Disease, Institute of Cardiovascular Research, Southwest Medical University,
2Department of Cardiology, the Affiliated Hospital of Southwest Medical University,
3Department of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology,
4Department of Pharmacology, University of Oxford
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