Addmore Shonhai

Department of Biochemistry & Microbiology, University of Venda

Research Area

Biochemistry

Biography

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JoVE Journal Publications

Article Total : 1	Year
Publication title	2024

Other Publications

Article	Year
Immunomodulatory activity of zinc peroxide (ZnO₂) and titanium dioxide (TiO₂) nanoparticles and their effects on DNA and protein integrity. Toxicology letters\| PubMed ID: 24631018	2014
DnaK protein alleviates toxicity induced by citrate-coated gold nanoparticles in Escherichia coli. PloS one\| PubMed ID: 25837593	2015
Overexpression, Purification and Characterisation of the Plasmodium falciparum Hsp70-z (PfHsp70-z) Protein. PloS one\| PubMed ID: 26083397	2015
Plasmodium falciparum Hop (PfHop) Interacts with the Hsp70 Chaperone in a Nucleotide-Dependent Fashion and Exhibits Ligand Selectivity. PloS one\| PubMed ID: 26267894	2015
Plasmodium falciparum Hsp70-z, an Hsp110 homologue, exhibits independent chaperone activity and interacts with Hsp70-1 in a nucleotide-dependent fashion. Cell stress & chaperones\| PubMed ID: 26894764	2016
Use of a Chimeric Hsp70 to Enhance the Quality of Recombinant Plasmodium falciparum S-Adenosylmethionine Decarboxylase Protein Produced in Escherichia coli. PloS one\| PubMed ID: 27031344	2016
Plasmodium falciparum Heat Shock Protein 70 Lacks Immune Modulatory Activity. Protein and peptide letters\| PubMed ID: 28201964	2017
Polymyxin B inhibits the chaperone activity of Plasmodium falciparum Hsp70. Cell stress & chaperones\| PubMed ID: 28455613	2017
Extracts Obtained from Pterocarpus angolensis DC and Ziziphus mucronata Exhibit Antiplasmodial Activity and Inhibit Heat Shock Protein 70 (Hsp70) Function. Molecules (Basel, Switzerland)\| PubMed ID: 28788073	2017
(-)-Epigallocatechin-3-Gallate Inhibits the Chaperone Activity of Plasmodium falciparum Hsp70 Chaperones and Abrogates Their Association with Functional Partners. Molecules (Basel, Switzerland)\| PubMed ID: 29206141	2017
The Presence of Toxic and Non-Toxic Cyanobacteria in the Sediments of the Limpopo River Basin: Implications for Human Health. Toxins\| PubMed ID: 29970791	2018
Structural and biochemical characterization of Plasmodium falciparum Hsp70-x reveals functional versatility of its C-terminal EEVN motif. Proteins\| PubMed ID: 30183110	2018
Heat Shock Proteins as Immunomodulants. Molecules (Basel, Switzerland)\| PubMed ID: 30388847	2018
Proteomic analysis of Plasmodium falciparum histone deacetylase 1 complex proteins. Experimental parasitology\| PubMed ID: 30682336	2019
Comparative structure-function features of Hsp70s of Plasmodium falciparum and human origins. Biophysical reviews\| PubMed ID: 31280465	2019
Partners in Mischief: Functional Networks of Heat Shock Proteins of and Their Influence on Parasite Virulence. Biomolecules\| PubMed ID: 31340488	2019
The Link That Binds: The Linker of Hsp70 as a Helm of the Protein's Function. Biomolecules\| PubMed ID: 31569820	2019
Plasmodium falciparum R2TP complex: driver of parasite Hsp90 function. Biophysical reviews\| PubMed ID: 31734827	2019
Small Molecule Inhibitors Targeting the Heat Shock Protein System of Human Obligate Protozoan Parasites. International journal of molecular sciences\| PubMed ID: 31775392	2019
Biophysical analysis of Plasmodium falciparum Hsp70-Hsp90 organising protein (PfHop) reveals a monomer that is characterised by folded segments connected by flexible linkers. PloS one\| PubMed ID: 32343703	2020
Comparative Characterization of Hsp70-1 Relative to DnaK Reveals the Functional Specificity of the Parasite Chaperone. Biomolecules\| PubMed ID: 32512819	2020
The Role of Non-Canonical Hsp70s (Hsp110/Grp170) in Cancer. Cells\| PubMed ID: 33525518	2021
Mutation of GGMP Repeat Segments of Hsp70-1 Compromises Chaperone Function and Hop Co-Chaperone Binding. International journal of molecular sciences\| PubMed ID: 33672387	2021
Characterisation of a unique linker segment of the Plasmodium falciparum cytosol localised Hsp110 chaperone. International journal of biological macromolecules\| PubMed ID: 33741370	2021
Design and synthesis of quinoline-pyrimidine inspired hybrids as potential plasmodial inhibitors. European journal of medicinal chemistry\| PubMed ID: 33744688	2021
'Meet the editor series'-Addmore Shonhai. Biophysical reviews\| PubMed ID: 33927784	2021
Supporting data on characterisation of linker switch mutants of heat shock protein 110 and canonical Hsp70. Data in brief\| PubMed ID: 34141839	2021
Characterization of an Atypical Hsp70 Demonstrates Its Cytosolic-Nuclear Localization and Modulation by Quercetin and Methylene Blue. International journal of molecular sciences\| PubMed ID: 34202520	2021
Heat Shock Proteins: Potential Modulators and Candidate Biomarkers of Peripartum Cardiomyopathy. Frontiers in cardiovascular medicine\| PubMed ID: 34222357	2021
The Role of Hsp70s in the Development and Pathogenicity of Plasmodium falciparum. Advances in experimental medicine and biology\| PubMed ID: 34569021	2021
Bioprospecting for Novel Heat Shock Protein Modulators: The New Frontier for Antimalarial Drug Discovery? Advances in experimental medicine and biology\| PubMed ID: 34569026	2021
Heat Shock Proteins of Malaria: Highlights and Future Prospects. Advances in experimental medicine and biology\| PubMed ID: 34569028	2021
Host cell stress response as a predictor of COVID-19 infectivity and disease progression. Frontiers in molecular biosciences\| PubMed ID: 36032680	2022
Inhibition of Hsp70-Hop partnership by 2-phenylthynesulfonamide. Frontiers in molecular biosciences\| PubMed ID: 36177352	2022
Human granzyme B binds Plasmodium falciparum Hsp70-x and mediates antiplasmodial activity in vitro. Cell stress & chaperones\| PubMed ID: 37074531	2023
The Genome of a Pigeonpea Compatible Rhizobial Strain '10ap3' Appears to Lack Common Nodulation Genes. Genes\| PubMed ID: 37239443	2023
2-Hydroxypropyl-β-cyclodextrin (HPβCD) as a Potential Therapeutic Agent for Breast Cancer. Cancers\| PubMed ID: 37345165	2023
Pharmacophore Model-Based Virtual Screening Workflow for Discovery of Inhibitors Targeting Hsp90. ACS omega\| PubMed ID: 37867657	2023
Insertion of GGMP repeat residues of Plasmodium falciparum Hsp70-1 in the lid of DnaK adversely impacts client recognition. International journal of biological macromolecules\| PubMed ID: 37981279	2024
The multi-faceted roles of R2TP complex span across regulation of gene expression, translation, and protein functional assembly. Biophysical reviews\| PubMed ID: 38192347	2023
Ursolic acid acetate and iso-mukaadial acetate bind to Plasmodium falciparum Hsp90, abrogating its chaperone function in vitro. Naunyn-Schmiedeberg's archives of pharmacology\| PubMed ID: 38252299	2024
Correction: Bopape et al. The Genome of a Pigeonpea Compatible Rhizobial Strain '10ap3' Appears to Lack Common Nodulation Genes. 2023, , 1084. Genes\| PubMed ID: 38255010	2024