Department of Molecular and Medical Pharmacology,
Crump Institute for Molecular Imaging,
Jonsson Comprehensive Cancer Center
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Asparagine promotes cancer cell proliferation through use as an amino acid exchange factor.
Nature communications Apr, 2016 | Pubmed ID: 27126896
Chronic IL-1β-induced inflammation regulates epithelial-to-mesenchymal transition memory phenotypes via epigenetic modifications in non-small cell lung cancer.
Scientific reports Jan, 2020 | Pubmed ID: 31941995
Author Correction: Chronic IL-1β-induced inflammation regulates epithelial-to-mesenchymal transition memory phenotypes via epigenetic modifications in non-small cell lung cancer.
Scientific reports Mar, 2020 | Pubmed ID: 32127587
Gene therapy for guanidinoacetate methyltransferase deficiency restores cerebral and myocardial creatine while resolving behavioral abnormalities.
Molecular therapy. Methods & clinical development Jun, 2022 | Pubmed ID: 35505663
Poly(trehalose methacrylate) as an Excipient for Insulin Stabilization: Mechanism and Safety.
ACS applied materials & interfaces Aug, 2022 | Pubmed ID: 35968684
Low-dose exposure to PBDE disrupts genomic integrity and innate immunity in mammary tissue.
Frontiers in genetics , 2022 | Pubmed ID: 36035174
M2 isoform of pyruvate kinase rewires glucose metabolism during radiation therapy to promote an antioxidant response and glioblastoma radioresistance.
Neuro-oncology Nov, 2023 | Pubmed ID: 37279645
Real-time resolution studies of the regulation of pyruvate-dependent lactate metabolism by hexokinases in single cells.
PloS one , 2023 | Pubmed ID: 37917627
89Zr-ImmunoPET for the Specific Detection of EMP2-Positive Tumors.
Molecular cancer therapeutics Jun, 2024 | Pubmed ID: 38417138
Real-time resolution studies of the regulation of lactate production by hexokinases binding to mitochondria in single cells.
PloS one , 2024 | Pubmed ID: 38457438
A Tumor Agnostic Therapeutic Strategy for Hexokinase 1-Null/Hexokinase 2-Positive Cancers.
Cancer research Dec, 2019 | Pubmed ID: 31434645
Metabolic Modifier Screen Reveals Secondary Targets of Protein Kinase Inhibitors within Nucleotide Metabolism.
Cell chemical biology 02, 2020 | Pubmed ID: 31734178
Comparison of the Efficacy and Sensitivity of Alternative PET Reporter Gene/PET Reporter Probe Systems That Minimize Biological Variables.
Methods in molecular biology (Clifton, N.J.) , 2020 | Pubmed ID: 32112389
Positron Emission Tomography Tracer Design of Targeted Synthetic Peptides via F-Sydnone Alkyne Cycloaddition.
Bioconjugate chemistry Sep, 2021 | Pubmed ID: 34415731
Spatial mapping of mitochondrial networks and bioenergetics in lung cancer.
Nature Mar, 2023 | Pubmed ID: 36922590
F-Labeled brain-penetrant EGFR tyrosine kinase inhibitors for PET imaging of glioblastoma.
Chemical science Dec, 2023 | Pubmed ID: 38075671
1University of California Los Angeles (UCLA) Cardiac Arrhythmia Center, UCLA Health System, David Geffen School of Medicine at UCLA,
2Neurocardiology Program of Excellence, UCLA,
3Department of Molecular and Medical Pharmacology, David Geffen School of Medicine at UCLA,
4Crump Institute for Molecular Imaging, David Geffen School of Medicine at UCLA,
5Jonsson Comprehensive Cancer Center, David Geffen School of Medicine at UCLA
Isabel L. Day1,2,
Mikayla Tamboline1,2,
Andrea Litwak1,2,
Andrea Sarabia1,2,
Yin Tintut3,4,5,
Linda L. Demer3,4,6,
Shili Xu1,2,7
1Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles,
2Crump Institute for Molecular Imaging, David Geffen School of Medicine, University of California, Los Angeles,
3Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles,
4Department of Physiology, David Geffen School of Medicine, University of California, Los Angeles,
5Department of Orthopaedic Surgery, David Geffen School of Medicine, University of California, Los Angeles,
6Department of Bioengineering, University of California, Los Angeles,
7Jonsson Comprehensive Cancer Center, University of California, Los Angeles
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