Institute of Biochemical Chemistry,
Biophysics,
and Bioengineering,
Institute of Biochemical Chemistry, Biophysics, and Bioengineering
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Quantum dots: an insight and perspective of their biological interaction and how this relates to their relevance for clinical use.
Theranostics , 2012 | Pubmed ID: 22896769
In vitro assessment of engineered nanomaterials using a hepatocyte cell line: cytotoxicity, pro-inflammatory cytokines and functional markers.
Nanotoxicology May, 2013 | Pubmed ID: 22263564
An in vitro liver model--assessing oxidative stress and genotoxicity following exposure of hepatocytes to a panel of engineered nanomaterials.
Particle and fibre toxicology Jul, 2012 | Pubmed ID: 22812506
Investigating the relationship between nanomaterial hazard and physicochemical properties: Informing the exploitation of nanomaterials within therapeutic and diagnostic applications.
Journal of controlled release : official journal of the Controlled Release Society Dec, 2012 | Pubmed ID: 22940205
Primary human hepatocytes versus hepatic cell line: assessing their suitability for in vitro nanotoxicology.
Nanotoxicology Nov, 2013 | Pubmed ID: 23009365
Effects of silver nanoparticles on the liver and hepatocytes in vitro.
Toxicological sciences : an official journal of the Society of Toxicology Feb, 2013 | Pubmed ID: 23086748
Engineered nanomaterial risk. Lessons learnt from completed nanotoxicology studies: potential solutions to current and future challenges.
Critical reviews in toxicology Jan, 2013 | Pubmed ID: 23126553
An in vitro assessment of panel of engineered nanomaterials using a human renal cell line: cytotoxicity, pro-inflammatory response, oxidative stress and genotoxicity.
BMC nephrology Apr, 2013 | Pubmed ID: 23617532
The role of Kupffer cells in the hepatic response to silver nanoparticles.
Nanotoxicology Aug, 2014 | Pubmed ID: 24344730
ITS-NANO - Prioritising nanosafety research to develop a stakeholder driven intelligent testing strategy.
Particle and fibre toxicology , 2014 | Pubmed ID: 24521051
Serum enhanced cytokine responses of macrophages to silica and iron oxide particles and nanomaterials: a comparison of serum to lung lining fluid and albumin dispersions.
Journal of applied toxicology : JAT Nov, 2014 | Pubmed ID: 24737200
Hepatic toxicology following single and multiple exposure of engineered nanomaterials utilising a novel primary human 3D liver microtissue model.
Particle and fibre toxicology Oct, 2014 | Pubmed ID: 25326698
Accumulation dynamics and acute toxicity of silver nanoparticles to Daphnia magna and Lumbriculus variegatus: implications for metal modeling approaches.
Environmental science & technology Apr, 2015 | Pubmed ID: 25756614
Nanomaterial categorization for assessing risk potential to facilitate regulatory decision-making.
ACS nano , 2015 | Pubmed ID: 25791861
Mechanism of neutrophil activation and toxicity elicited by engineered nanomaterials.
Toxicology in vitro : an international journal published in association with BIBRA Aug, 2015 | Pubmed ID: 25962642
Comparative hazard identification by a single dose lung exposure of zinc oxide and silver nanomaterials in mice.
PloS one , 2015 | Pubmed ID: 25966284
Multi-walled carbon nanotube induced frustrated phagocytosis, cytotoxicity and pro-inflammatory conditions in macrophages are length dependent and greater than that of asbestos.
Toxicology in vitro : an international journal published in association with BIBRA Oct, 2015 | Pubmed ID: 26086123
Assessing the acute hazards of zinc oxide nanomaterials to Lumbriculus variegatus.
Ecotoxicology (London, England) Aug, 2015 | Pubmed ID: 26173674
Exploring the cellular and tissue uptake of nanomaterials in a range of biological samples using multimodal nonlinear optical microscopy.
Nanotechnology Dec, 2015 | Pubmed ID: 26584818
A rapid screening assay for identifying mycobacteria targeted nanoparticle antibiotics.
Nanotoxicology Aug, 2016 | Pubmed ID: 26618564
Impact of serum as a dispersion agent for in vitro and in vivo toxicological assessments of TiO nanoparticles.
Archives of toxicology Jan, 2017 | Pubmed ID: 26872950
A Multilaboratory Toxicological Assessment of a Panel of 10 Engineered Nanomaterials to Human Health--ENPRA Project--The Highlights, Limitations, and Current and Future Challenges.
Journal of toxicology and environmental health. Part B, Critical reviews , 2016 | Pubmed ID: 27030582
Expert consensus on an in vitro approach to assess pulmonary fibrogenic potential of aerosolized nanomaterials.
Archives of toxicology Jul, 2016 | Pubmed ID: 27121469
Organ burden and pulmonary toxicity of nano-sized copper (II) oxide particles after short-term inhalation exposure.
Nanotoxicology Oct, 2016 | Pubmed ID: 27132941
Approaches to Develop Alternative Testing Strategies to Inform Human Health Risk Assessment of Nanomaterials.
Risk analysis : an official publication of the Society for Risk Analysis Aug, 2016 | Pubmed ID: 27285586
Neurodegenerative and neurological disorders by small inhaled particles.
Neurotoxicology Sep, 2016 | Pubmed ID: 27448464
Synthesis, characterization and evaluation of in vitro toxicity in hepatocytes of linear polyesters with varied aromatic and aliphatic co-monomers.
Journal of controlled release : official journal of the Controlled Release Society Dec, 2016 | Pubmed ID: 27498019
Advancing Risk Analysis for Nanoscale Materials: Report from an International Workshop on the Role of Alternative Testing Strategies for Advancement.
Risk analysis : an official publication of the Society for Risk Analysis Aug, 2016 | Pubmed ID: 27510619
A Tractable Method for Measuring Nanomaterial Risk Using Bayesian Networks.
Nanoscale research letters Dec, 2016 | Pubmed ID: 27848238
Complete transformation of ZnO and CuO nanoparticles in culture medium and lymphocyte cells during toxicity testing.
Nanotoxicology Mar, 2017 | Pubmed ID: 28165880
Silver Nanoparticles and Metallic Silver Interfere with the Griess Reaction: Reduction of Azo Dye Formation via a Competing Sandmeyer-Like Reaction.
Chemical research in toxicology Apr, 2017 | Pubmed ID: 28282135
The effect of aluminium and sodium impurities on the in vitro toxicity and pro-inflammatory potential of cristobalite.
Environmental research Nov, 2017 | Pubmed ID: 28802207
Development of an in vitro co-culture model to mimic the human intestine in healthy and diseased state.
Toxicology in vitro : an international journal published in association with BIBRA Dec, 2017 | Pubmed ID: 28807632
Impact of copper oxide nanomaterials on differentiated and undifferentiated Caco-2 intestinal epithelial cells; assessment of cytotoxicity, barrier integrity, cytokine production and nanomaterial penetration.
Particle and fibre toxicology Aug, 2017 | Pubmed ID: 28835236
Nanomaterials Versus Ambient Ultrafine Particles: An Opportunity to Exchange Toxicology Knowledge.
Environmental health perspectives 10, 2017 | Pubmed ID: 29017987
Aligning nanotoxicology with the 3Rs: What is needed to realise the short, medium and long-term opportunities?
Regulatory toxicology and pharmacology : RTP Dec, 2017 | Pubmed ID: 29069581
Transcriptional profiling reveals gene expression changes associated with inflammation and cell proliferation following short-term inhalation exposure to copper oxide nanoparticles.
Journal of applied toxicology : JAT Mar, 2018 | Pubmed ID: 29094763
Adoption of in vitro systems and zebrafish embryos as alternative models for reducing rodent use in assessments of immunological and oxidative stress responses to nanomaterials.
Critical reviews in toxicology Mar, 2018 | Pubmed ID: 29239234
The Essential Elements of a Risk Governance Framework for Current and Future Nanotechnologies.
Risk analysis : an official publication of the Society for Risk Analysis Jul, 2018 | Pubmed ID: 29240986
Transformations of Nanoenabled Copper Formulations Govern Release, Antifungal Effectiveness, and Sustainability throughout the Wood Protection Lifecycle.
Environmental science & technology Feb, 2018 | Pubmed ID: 29373787
Quantitative human health risk assessment along the lifecycle of nano-scale copper-based wood preservatives.
Nanotoxicology Sep, 2018 | Pubmed ID: 29893192
Assessing the bioactivity of crystalline silica in heated high-temperature insulation wools.
Inhalation toxicology , 2018 | Pubmed ID: 30328741
Toxicity of copper oxide and basic copper carbonate nanoparticles after short-term oral exposure in rats.
Nanotoxicology Feb, 2019 | Pubmed ID: 30451559
Nanodelivery systems and stabilized solid-drug nanoparticles for orally administered medicine: current landscape.
International journal of nanomedicine , 2018 | Pubmed ID: 30510419
The influence of organic modification on the cytotoxicity of clay particles to keratinocytes, hepatocytes and macrophages; an investigation towards the safe use of polymer-clay nanocomposite packaging.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association Apr, 2019 | Pubmed ID: 30797875
The importance of inter-individual Kupffer cell variability in the governance of hepatic toxicity in a 3D primary human liver microtissue model.
Scientific reports May, 2019 | Pubmed ID: 31086251
Using 3D gastrointestinal tract in vitro models with microfold cells and mucus secreting ability to assess the hazard of copper oxide nanomaterials.
Journal of nanobiotechnology May, 2019 | Pubmed ID: 31113462
The mechanism-based toxicity screening of particles with use in the food and nutrition sector via the ToxTracker reporter system.
Toxicology in vitro : an international journal published in association with BIBRA Dec, 2019 | Pubmed ID: 31279906
The variances in cytokine production profiles from non- or activated THP-1, Kupffer cell and human blood derived primary macrophages following exposure to either alcohol or a panel of engineered nanomaterials.
PloS one , 2019 | Pubmed ID: 31393970
Assessment of nanomaterial-induced hepatotoxicity using a 3D human primary multi-cellular microtissue exposed repeatedly over 21 days - the suitability of the in vitro system as an in vivo surrogate.
Particle and fibre toxicology Nov, 2019 | Pubmed ID: 31739797
Ongoing inflammation enhances the toxicity of engineered nanomaterials: Application of an in vitro co-culture model of the healthy and inflamed intestine.
Toxicology in vitro : an international journal published in association with BIBRA Mar, 2020 | Pubmed ID: 31760064
Use of EpiAlveolar Lung Model to Predict Fibrotic Potential of Multiwalled Carbon Nanotubes.
ACS nano Apr, 2020 | Pubmed ID: 32167743
Polylactic is a Sustainable, Low Absorption, Low Autofluorescence Alternative to Other Plastics for Microfluidic and Organ-on-Chip Applications.
Analytical chemistry May, 2020 | Pubmed ID: 32233401
A review of hepatic nanotoxicology - summation of recent findings and considerations for the next generation of study designs.
Journal of toxicology and environmental health. Part B, Critical reviews May, 2020 | Pubmed ID: 32321383
A Method to Assess the Relevance of Nanomaterial Dissolution During Reactivity Testing.
Materials (Basel, Switzerland) May, 2020 | Pubmed ID: 32414026
Improving Quality in Nanoparticle-Induced Cytotoxicity Testing by a Tiered Inter-Laboratory Comparison Study.
Nanomaterials (Basel, Switzerland) Jul, 2020 | Pubmed ID: 32707981
An In Vitro Lung System to Assess the Proinflammatory Hazard of Carbon Nanotube Aerosols.
International journal of molecular sciences Jul, 2020 | Pubmed ID: 32727099
Risk Management Framework for Nano-Biomaterials Used in Medical Devices and Advanced Therapy Medicinal Products.
Materials (Basel, Switzerland) Oct, 2020 | Pubmed ID: 33066064
Neutrophil activation by nanomaterials : comparing strengths and limitations of primary human cells with those of an immortalized (HL-60) cell line.
Nanotoxicology Feb, 2021 | Pubmed ID: 33272088
Time dependent impact of copper oxide nanomaterials on the expression of genes associated with oxidative stress, metal binding, inflammation and mucus secretion in single and co-culture intestinal in vitro models.
Toxicology in vitro : an international journal published in association with BIBRA Aug, 2021 | Pubmed ID: 33839236
Particulate and drug-induced toxicity assessed in novel quadruple cell human primary hepatic disease models of steatosis and pre-fibrotic NASH.
Archives of toxicology Jan, 2022 | Pubmed ID: 34668024
Grouping Hypotheses and an Integrated Approach to Testing and Assessment of Nanomaterials Following Oral Ingestion.
Nanomaterials (Basel, Switzerland) Oct, 2021 | Pubmed ID: 34685072
An Integrated Approach to Testing and Assessment to Support Grouping and Read-Across of Nanomaterials After Inhalation Exposure.
Applied in vitro toxicology Sep, 2021 | Pubmed ID: 34746334
An in vitro assessment of the toxicity of two-dimensional synthetic and natural layered silicates.
Toxicology in vitro : an international journal published in association with BIBRA Feb, 2022 | Pubmed ID: 34801683
Acute hazard assessment of silver nanoparticles following intratracheal instillation, oral and intravenous injection exposures.
Nanotoxicology Dec, 2021 | Pubmed ID: 35015612
Development of a standard operating procedure for the DCFH-DA acellular assessment of reactive oxygen species produced by nanomaterials.
Toxicology mechanisms and methods Jul, 2022 | Pubmed ID: 35086424
The Road to Achieving the European Commission's Chemicals Strategy for Nanomaterial Sustainability-A PATROLS Perspective on New Approach Methodologies.
Small (Weinheim an der Bergstrasse, Germany) Apr, 2022 | Pubmed ID: 35324067
An investigation of the hepatic toxicity of PEGylated polymeric redox responsive nanoparticles.
RSC advances Apr, 2022 | Pubmed ID: 35496338
The application of existing genotoxicity methodologies for grouping of nanomaterials: towards an integrated approach to testing and assessment.
Particle and fibre toxicology May, 2022 | Pubmed ID: 35525968
Acute waterborne and chronic sediment toxicity of silver and titanium dioxide nanomaterials towards the oligochaete, Lumbriculus variegatus.
NanoImpact Jan, 2021 | Pubmed ID: 35559780
How can we justify grouping of nanoforms for hazard assessment? Concepts and tools to quantify similarity.
NanoImpact Jan, 2022 | Pubmed ID: 35559874
Bayesian based similarity assessment of nanomaterials to inform grouping.
NanoImpact Jan, 2022 | Pubmed ID: 35559895
Pulmonary toxicity and gene expression changes after short-term inhalation exposure to surface-modified copper oxide nanoparticles.
NanoImpact Apr, 2021 | Pubmed ID: 35559970
An integrated approach to testing and assessment of high aspect ratio nanomaterials and its application for grouping based on a common mesothelioma hazard.
NanoImpact Apr, 2021 | Pubmed ID: 35559971
Determining nanoform similarity via assessment of surface reactivity by abiotic and in vitro assays.
NanoImpact Apr, 2022 | Pubmed ID: 35560290
Integrated approaches to testing and assessment for grouping nanomaterials following dermal exposure.
Nanotoxicology Apr, 2022 | Pubmed ID: 35704509
How to formulate hypotheses and IATAs to support grouping and read-across of nanoforms.
ALTEX , 2023 | Pubmed ID: 35796348
Transgenic zebrafish larvae as a non-rodent alternative model to assess pro-inflammatory (neutrophil) responses to nanomaterials.
Nanotoxicology Apr, 2022 | Pubmed ID: 35797989
Grouping MWCNTs based on their similar potential to cause pulmonary hazard after inhalation: a case-study.
Particle and fibre toxicology Jul, 2022 | Pubmed ID: 35854357
Assessing the transferability and reproducibility of 3D in vitro liver models from primary human multi-cellular microtissues to cell-line based HepG2 spheroids.
Toxicology in vitro : an international journal published in association with BIBRA Dec, 2022 | Pubmed ID: 36108805
Comparison of In Vitro Approaches to Assess the Antibacterial Effects of Nanomaterials.
Journal of functional biomaterials Nov, 2022 | Pubmed ID: 36412895
Editorial to the special issue on "similarity assessment of nanoforms: Concepts, tools and case studies of the GRACIOUS project".
NanoImpact Oct, 2022 | Pubmed ID: 36427811
Grouping of orally ingested silica nanomaterials via use of an integrated approach to testing and assessment to streamline risk assessment.
Particle and fibre toxicology Dec, 2022 | Pubmed ID: 36461106
Comparative, collaborative, and integrative risk governance for emerging technologies.
Environment systems & decisions May, 2018 | Pubmed ID: 37829286
Critical aspects in dissolution testing of nanomaterials in the oro-gastrointestinal tract: the relevance of juice composition for hazard identification and grouping.
Nanoscale advances Jan, 2024 | Pubmed ID: 38298600
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