Department of Neurological Surgery
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Classification of current anticancer immunotherapies.
Oncotarget Dec, 2014 | Pubmed ID: 25537519
CD200 in CNS tumor-induced immunosuppression: the role for CD200 pathway blockade in targeted immunotherapy.
Journal for immunotherapy of cancer , 2014 | Pubmed ID: 25598973
Transgene-derived overexpression of miR-17-92 in CD8+ T-cells confers enhanced cytotoxic activity.
Biochemical and biophysical research communications Mar, 2015 | Pubmed ID: 25677619
Abstracts of the 29th Annual Scientific Meeting of the Society for Immunotherapy of Cancer (SITC).
Journal for immunotherapy of cancer , 2014 | Pubmed ID: 25746013
Protective role of STING against gliomagenesis: Rational use of STING agonist in anti-glioma immunotherapy.
Oncoimmunology Apr, 2015 | Pubmed ID: 26137417
Immunotherapy response assessment in neuro-oncology: a report of the RANO working group.
The Lancet. Oncology Nov, 2015 | Pubmed ID: 26545842
IDH mutant gliomas escape natural killer cell immune surveillance by downregulation of NKG2D ligand expression.
Neuro-oncology Oct, 2016 | Pubmed ID: 27116977
Cellular immunotherapy for malignant gliomas.
Expert opinion on biological therapy Oct, 2016 | Pubmed ID: 27434205
Detection of inflammatory cell function using (13)C magnetic resonance spectroscopy of hyperpolarized [6-(13)C]-arginine.
Scientific reports Aug, 2016 | Pubmed ID: 27507680
Is the immune response a friend or foe for viral therapy of glioma?
Neuro-oncology Jul, 2017 | Pubmed ID: 28874006
Novel and shared neoantigen derived from histone 3 variant H3.3K27M mutation for glioma T cell therapy.
The Journal of experimental medicine Jan, 2018 | Pubmed ID: 29203539
Fluorine-19 nuclear magnetic resonance of chimeric antigen receptor T cell biodistribution in murine cancer model.
Scientific reports Dec, 2017 | Pubmed ID: 29255242
Single-cell profiling of human gliomas reveals macrophage ontogeny as a basis for regional differences in macrophage activation in the tumor microenvironment.
Genome biology Dec, 2017 | Pubmed ID: 29262845
Antigenic expression and spontaneous immune responses support the use of a selected peptide set from the IMA950 glioblastoma vaccine for immunotherapy of grade II and III glioma.
Oncoimmunology , 2018 | Pubmed ID: 29308320
Immunotherapy of Primary Brain Tumors: Facts and Hopes.
Clinical cancer research : an official journal of the American Association for Cancer Research Nov, 2018 | Pubmed ID: 29871908
Cell penetrating peptide functionalized perfluorocarbon nanoemulsions for targeted cell labeling and enhanced fluorine-19 MRI detection.
Magnetic resonance in medicine Mar, 2020 | Pubmed ID: 31631402
Treatment-induced lesions in newly diagnosed glioblastoma patients undergoing chemoradiotherapy and heat-shock protein vaccine therapy.
Journal of neuro-oncology Jan, 2020 | Pubmed ID: 31728884
Perspectives in immunotherapy: meeting report from the "Immunotherapy Bridge 2018" (28-29 November, 2018, Naples, Italy).
Journal for immunotherapy of cancer Nov, 2019 | Pubmed ID: 31783779
Tumor antigens in glioma.
Seminars in immunology Feb, 2020 | Pubmed ID: 32037183
T-Cell based therapies for overcoming neuroanatomical and immunosuppressive challenges within the glioma microenvironment.
Journal of neuro-oncology Apr, 2020 | Pubmed ID: 32185647
Introduction to immunotherapy for brain tumor patients: challenges and future perspectives.
Neuro-oncology practice Oct, 2020 | Pubmed ID: 33014387
Considerations when treating high-grade pediatric glioma patients with immunotherapy.
Expert review of neurotherapeutics Feb, 2021 | Pubmed ID: 33225764
Zika virus oncolytic activity requires CD8+ T cells and is boosted by immune checkpoint blockade.
JCI insight Jan, 2021 | Pubmed ID: 33232299
Current Advances in Immunotherapy for Glioblastoma.
Current oncology reports Jan, 2021 | Pubmed ID: 33496872
Assessing Oximetry Response to Chimeric Antigen Receptor T-cell Therapy against Glioma with F MRI in a Murine Model.
Radiology. Imaging cancer Jan, 2021 | Pubmed ID: 33575659
SynNotch-CAR T cells overcome challenges of specificity, heterogeneity, and persistence in treating glioblastoma.
Science translational medicine Apr, 2021 | Pubmed ID: 33910979
Deep immune profiling reveals targetable mechanisms of immune evasion in immune checkpoint inhibitor-refractory glioblastoma.
Journal for immunotherapy of cancer Jun, 2021 | Pubmed ID: 34083417
IFN-γ- and IL-17-producing CD8 T (Tc17-1) cells in combination with poly-ICLC and peptide vaccine exhibit antiglioma activity.
Journal for immunotherapy of cancer Jun, 2021 | Pubmed ID: 34193567
Inhibition of D-2HG leads to upregulation of a proinflammatory gene signature in a novel HLA-A2/HLA-DR1 transgenic mouse model of IDH1R132H-expressing glioma.
Journal for immunotherapy of cancer May, 2022 | Pubmed ID: 35606087
The future of cancer immunotherapy for brain tumors: a collaborative workshop.
Journal of translational medicine May, 2022 | Pubmed ID: 35606815
RASA2 ablation in T cells boosts antigen sensitivity and long-term function.
Nature Sep, 2022 | Pubmed ID: 36002574
Magnetic Resonance Spectroscopy Metabolites as Biomarkers of Disease Status in Pediatric Diffuse Intrinsic Pontine Gliomas (DIPG) Treated with Glioma-Associated Antigen Peptide Vaccines.
Cancers Dec, 2022 | Pubmed ID: 36497477
Correspondence on 'H3.3K27M mutation is not a suitable target for immunotherapy in HLA-A2+ patients with diffuse midline glioma' by Immisch .
Journal for immunotherapy of cancer Mar, 2023 | Pubmed ID: 36944450
Sex-Biased T-cell Exhaustion Drives Differential Immune Responses in Glioblastoma.
Cancer discovery Sep, 2023 | Pubmed ID: 37378557
Glioblastoma evolution and heterogeneity from a 3D whole-tumor perspective.
Cell Jan, 2024 | Pubmed ID: 38242087
Challenges in the discovery of tumor-specific alternative splicing-derived cell-surface antigens in glioma.
Scientific reports Mar, 2024 | Pubmed ID: 38493204
IRF8-driven reprogramming of the immune microenvironment enhances anti-tumor adaptive immunity and reduces immunosuppression in murine glioblastoma.
bioRxiv : the preprint server for biology Apr, 2024 | Pubmed ID: 38617245
A Roadmap of CAR-T-Cell Therapy in Glioblastoma: Challenges and Future Perspectives.
Cells Apr, 2024 | Pubmed ID: 38727262
IRF8-driven reprogramming of the immune microenvironment enhances anti-tumor adaptive immunity and reduces immunosuppression in murine glioblastoma.
Neuro-oncology Aug, 2024 | Pubmed ID: 39115195
Activating the dark genome to illuminate cancer vaccine targets.
Nature genetics Sep, 2024 | Pubmed ID: 39223317
Kisoo Kim1,2,
Marco Gallus3,
Tianrun Xiao1,
Akshay S. Parchure4,
Bhavya R. Shah4,
Hideho Okada3,
Chris Diederich5,
Eugene Ozhinsky*,1,
Kazim Narsinh*,1
1Department of Radiology & Biomedical Imaging, University of California, San Francisco,
2Department of Biomedical Engineering, Kyung Hee University,
3Department of Neurological Surgery, University of California, San Francisco,
4, University of Texas Southwestern Medical Center,
5Department of Radiation Oncology, University of California, San Francisco
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