Department of Chemistry
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Solution structure of domain 5 of a group II intron ribozyme reveals a new RNA motif.
Nature structural & molecular biology Feb, 2004 | Pubmed ID: 14745440
Acid-base and metal-ion binding properties of the RNA dinucleotide uridylyl-(5'-->3')-[5']uridylate (pUpU3-).
Chemistry (Weinheim an der Bergstrasse, Germany) Jul, 2005 | Pubmed ID: 15861476
Acid-base properties of the nucleic-acid model 2'-deoxyguanylyl(5'-->3')-2'-deoxy-5'-guanylate, d(pGpG)3-, and of related guanine derivatives.
Organic & biomolecular chemistry Mar, 2006 | Pubmed ID: 16525552
Metal-ion-coordinating properties of the dinucleotide 2'-deoxyguanylyl(5'-->3')-2'-deoxy-5'-guanylate (d(pGpG)3-): isomeric equilibria including macrochelated complexes relevant for nucleic acids.
Chemistry (Weinheim an der Bergstrasse, Germany) , 2007 | Pubmed ID: 17121397
Solution structure of domain 6 from a self-splicing group II intron ribozyme: a Mg(2+) binding site is located close to the stacked branch adenosine.
Chembiochem : a European journal of chemical biology Feb, 2007 | Pubmed ID: 17200997
Alternative roles for metal ions in enzyme catalysis and the implications for ribozyme chemistry.
Chemical reviews Jan, 2007 | Pubmed ID: 17212472
Binding interaction of [Re(H2O)3(CO)3]+ with the DNA fragment d(CpGpG).
Inorganic chemistry Dec, 2007 | Pubmed ID: 18001120
Determination of the intrinsic affinities of multiple site-specific Mg(2+) ions coordinated to domain 6 of a group II intron ribozyme.
Inorganic chemistry Dec, 2007 | Pubmed ID: 18044881
Discrimination in metal-ion binding to RNA dinucleotides with a non-bridging oxygen or sulfur in the phosphate diester link.
Chemistry (Weinheim an der Bergstrasse, Germany) , 2008 | Pubmed ID: 18270983
Using in vitro transcription to construct scaffolds for one-dimensional arrays of mercuric ions.
Journal of inorganic biochemistry , 2008 | Pubmed ID: 18289686
The corrin moiety of coenzyme B12 is the determinant for switching the btuB riboswitch of E. coli.
Chembiochem : a European journal of chemical biology Jun, 2008 | Pubmed ID: 18506875
Divalent metal ions tune the self-splicing reaction of the yeast mitochondrial group II intron Sc.ai5gamma.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry Aug, 2008 | Pubmed ID: 18528718
Comparison of the acid-base properties of ribose and 2'-deoxyribose nucleotides.
Chemistry (Weinheim an der Bergstrasse, Germany) , 2008 | Pubmed ID: 18567033
Single-molecule studies of group II intron ribozymes.
Proceedings of the National Academy of Sciences of the United States of America Sep, 2008 | Pubmed ID: 18772388
Effect of the ribose versus 2'-deoxyribose residue on the metal ion-binding properties of purine nucleotides.
Dalton transactions (Cambridge, England : 2003) Oct, 2008 | Pubmed ID: 18827944
Divalent metal ions promote the formation of the 5'-splice site recognition complex in a self-splicing group II intron.
Journal of inorganic biochemistry Dec, 2008 | Pubmed ID: 18842303
Ca2+ induces the formation of two distinct subpopulations of group II intron molecules.
Angewandte Chemie (International ed. in English) , 2009 | Pubmed ID: 19924747
Controlling ribozyme activity by metal ions.
Current opinion in chemical biology Apr, 2010 | Pubmed ID: 20047851
Metal ion-N7 coordination in a ribozyme branch domain by NMR.
Journal of inorganic biochemistry May, 2010 | Pubmed ID: 20170966
A stability concept for metal ion coordination to single-stranded nucleic acids and affinities of individual sites.
Accounts of chemical research Jul, 2010 | Pubmed ID: 20235593
The change of corrin-amides to carboxylates leads to altered structures of the B12-responding btuB riboswitch.
Chemical communications (Cambridge, England) Jan, 2011 | Pubmed ID: 20830434
Solution structure of a DNA double helix with consecutive metal-mediated base pairs.
Nature chemistry Mar, 2010 | Pubmed ID: 21124482
Shaping RNA structures with metal ions and metal ion complexes.
Chimia , 2010 | Pubmed ID: 21140903
Stability and structure of mixed-ligand metal ion complexes that contain Ni2+, Cu2+, or Zn2+, and Histamine, as well as adenosine 5'-triphosphate (ATP4-) or uridine 5'-triphosphate (UTP(4-): an intricate network of equilibria.
Chemistry (Weinheim an der Bergstrasse, Germany) May, 2011 | Pubmed ID: 21465580
Probing the metal-ion-binding strength of the hydroxyl group.
Chemical reviews Aug, 2011 | Pubmed ID: 21595429
MINAS--a database of Metal Ions in Nucleic AcidS.
Nucleic acids research Jan, 2012 | Pubmed ID: 22096233
Characterization of metal ion-nucleic acid interactions in solution.
Metal ions in life sciences , 2012 | Pubmed ID: 22210334
Single molecule FRET characterization of large ribozyme folding.
Methods in molecular biology (Clifton, N.J.) , 2012 | Pubmed ID: 22315073
Metal ion-RNA interactions studied via multinuclear NMR.
Methods in molecular biology (Clifton, N.J.) , 2012 | Pubmed ID: 22315074
Unusually high-affinity Mg(2+) binding at the AU-rich sequence within the antiterminator hairpin of a Mg(2+) riboswitch.
Chemistry & biodiversity Sep, 2012 | Pubmed ID: 22976989
NMR spectroscopy in bioinorganic chemistry.
Chimia , 2012 | Pubmed ID: 23146267
The structural stabilization of the κ three-way junction by Mg(II) represents the first step in the folding of a group II intron.
Nucleic acids research Feb, 2013 | Pubmed ID: 23275550
Helicase-mediated changes in RNA structure at the single-molecule level.
RNA biology Jan, 2013 | Pubmed ID: 23353571
Complex formation of cadmium with sugar residues, nucleobases, phosphates, nucleotides, and nucleic acids.
Metal ions in life sciences , 2013 | Pubmed ID: 23430775
Intrinsic acid-base properties of a hexa-2'-deoxynucleoside pentaphosphate, d(ApGpGpCpCpT): neighboring effects and isomeric equilibria.
Chemistry (Weinheim an der Bergstrasse, Germany) Jun, 2013 | Pubmed ID: 23595830
Distance-dependent duplex DNA destabilization proximal to G-quadruplex/i-motif sequences.
Nucleic acids research Aug, 2013 | Pubmed ID: 23771141
Kinetic subpopulations detected by single-molecule spectroscopy: fundamental property of functional nucleic acids or experimental artefact?
Chimia , 2013 | Pubmed ID: 23967697
Structure and conformational dynamics of the domain 5 RNA hairpin of a bacterial group II intron revealed by solution nuclear magnetic resonance and molecular dynamics simulations.
Biochemistry Oct, 2013 | Pubmed ID: 24001362
Diversity of cobalamin riboswitches in the corrinoid-producing organohalide respirer Desulfitobacterium hafniense.
Journal of bacteriology Nov, 2013 | Pubmed ID: 24039263
Monitoring global structural changes and specific metal-ion-binding sites in RNA by in-line probing and Tb(III) cleavage.
Methods in molecular biology (Clifton, N.J.) , 2014 | Pubmed ID: 24136602
Mg(2+)-induced conformational changes in the btuB riboswitch from E. coli.
RNA (New York, N.Y.) Jan, 2014 | Pubmed ID: 24243114
BOBA FRET: bootstrap-based analysis of single-molecule FRET data.
PloS one , 2013 | Pubmed ID: 24386343
NMR structure of the 5' splice site in the group IIB intron Sc.ai5γ--conformational requirements for exon-intron recognition.
RNA (New York, N.Y.) Mar, 2014 | Pubmed ID: 24448450
Structure determination of noncanonical RNA motifs guided by ¹H NMR chemical shifts.
Nature methods Apr, 2014 | Pubmed ID: 24584194
Solution structure and metal ion binding sites of the human CPEB3 ribozyme's P4 domain.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry Aug, 2014 | Pubmed ID: 24652468
Synthesis, physico-chemical properties and biological analysis of newly obtained copper(II) complexes with pyrazole derivatives.
Journal of inorganic biochemistry Jun, 2014 | Pubmed ID: 24662465
The role of Mg(II) in DNA cleavage site recognition in group II intron ribozymes: solution structure and metal ion binding sites of the RNA-DNA complex.
The Journal of biological chemistry Jul, 2014 | Pubmed ID: 24895129
The AdoCbl-riboswitch interaction investigated by in-line probing and surface plasmon resonance spectroscopy (SPR).
Methods in enzymology , 2014 | Pubmed ID: 25432761
Cation-induced kinetic heterogeneity of the intron-exon recognition in single group II introns.
Proceedings of the National Academy of Sciences of the United States of America Mar, 2015 | Pubmed ID: 25737541
Strategy for Internal Labeling of Large RNAs with Minimal Perturbation by Using Fluorescent PNA.
Chembiochem : a European journal of chemical biology Jun, 2015 | Pubmed ID: 25872497
Explicit analytic equations for multimolecular thermal melting curves.
Biophysical chemistry Jul, 2015 | Pubmed ID: 25910861
Protonation-Dependent Base Flipping at Neutral pH in the Catalytic Triad of a Self-Splicing Bacterial Group II Intron.
Angewandte Chemie (International ed. in English) Aug, 2015 | Pubmed ID: 26119804
Studying metal ion binding properties of a three-way junction RNA by heteronuclear NMR.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry Jun, 2016 | Pubmed ID: 26880094
Secondary structure confirmation and localization of Mg2+ ions in the mammalian CPEB3 ribozyme.
RNA (New York, N.Y.) May, 2016 | Pubmed ID: 26966151
The X-ray Structures of Six Octameric RNA Duplexes in the Presence of Different Di- and Trivalent Cations.
International journal of molecular sciences Jun, 2016 | Pubmed ID: 27355942
Sequence-Specific Post-Synthetic Oligonucleotide Labeling for Single-Molecule Fluorescence Applications.
ACS chemical biology Sep, 2016 | Pubmed ID: 27409145
Distinct differences in metal ion specificity of RNA and DNA G-quadruplexes.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry Dec, 2016 | Pubmed ID: 27704222
An atomistic view on carbocyanine photophysics in the realm of RNA.
Physical chemistry chemical physics : PCCP Oct, 2016 | Pubmed ID: 27783069
Influence of pH and Mg(ii) on the catalytic core domain 5 of a bacterial group II intron.
Dalton transactions (Cambridge, England : 2003) Mar, 2017 | Pubmed ID: 28265619
Tb-Cleavage Assays Reveal Specific Mg Binding Sites Necessary to Pre-fold the Riboswitch for AdoCbl Binding.
Frontiers in chemistry , 2017 | Pubmed ID: 28377919
Site-specific dual-color labeling of long RNAs for single-molecule spectroscopy.
Nucleic acids research Feb, 2018 | Pubmed ID: 29136199
Specific phosphorothioate substitution within domain 6 of a group II intron ribozyme leads to changes in local structure and metal ion binding.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry Jan, 2018 | Pubmed ID: 29218637
Celebrating Helmut Sigel.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry Jan, 2018 | Pubmed ID: 29218638
Simulations of camera-based single-molecule fluorescence experiments.
PloS one , 2018 | Pubmed ID: 29652886
Optimal molecular crowding accelerates group II intron folding and maximizes catalysis.
Proceedings of the National Academy of Sciences of the United States of America Nov, 2018 | Pubmed ID: 30397128
The Bioinorganic Periodic Table.
Chimia Mar, 2019 | Pubmed ID: 30890214
NMR solution structure of tricyclo-DNA containing duplexes: insight into enhanced thermal stability and nuclease resistance.
Nucleic acids research May, 2019 | Pubmed ID: 30916334
Stick, Flick, Click: DNA-guided Fluorescent Labeling of Long RNA for Single-molecule FRET.
Chimia Apr, 2019 | Pubmed ID: 30975253
Concerted dynamics of metallo-base pairs in an A/B-form helical transition.
Nature communications Oct, 2019 | Pubmed ID: 31645548
Site-Specific Dual-Color Labeling of Long RNAs.
Methods in molecular biology (Clifton, N.J.) , 2020 | Pubmed ID: 31889263
Metal ions and sugar puckering balance single-molecule kinetic heterogeneity in RNA and DNA tertiary contacts.
Nature communications Jan, 2020 | Pubmed ID: 31913262
Encapsulation of Fluorescently Labeled RNAs into Surface-Tethered Vesicles for Single-Molecule FRET Studies in TIRF Microscopy.
Methods in molecular biology (Clifton, N.J.) , 2020 | Pubmed ID: 32006303
Screening for potential interaction partners with surface plasmon resonance imaging coupled to MALDI mass spectrometry.
Analytical biochemistry Jul, 2021 | Pubmed ID: 33857502
Puf6 primes 60S pre-ribosome nuclear export at low temperature.
Nature communications Aug, 2021 | Pubmed ID: 34349113
FRETraj: integrating single-molecule spectroscopy with molecular dynamics.
Bioinformatics (Oxford, England) Nov, 2021 | Pubmed ID: 34478493
Single-Molecule Kinetic Studies of Nucleic Acids by Förster Resonance Energy Transfer.
Methods in molecular biology (Clifton, N.J.) , 2022 | Pubmed ID: 35226322
Chemical Dual End-Labeling of Large Ribozymes.
Methods in molecular biology (Clifton, N.J.) , 2022 | Pubmed ID: 35226323
Coordination Chemistry of Nucleotides and Antivirally Active Acyclic Nucleoside Phosphonates, including Mechanistic Considerations.
Molecules (Basel, Switzerland) Apr, 2022 | Pubmed ID: 35565975
Magnesium(II)-ATP Complexes in 1-Ethyl-3-Methylimidazolium Acetate Solutions Characterized by Mg β-Radiation-Detected NMR Spectroscopy.
Angewandte Chemie (International ed. in English) Aug, 2022 | Pubmed ID: 35718746
A blind benchmark of analysis tools to infer kinetic rate constants from single-molecule FRET trajectories.
Nature communications Sep, 2022 | Pubmed ID: 36104339
The structural features of the ligand-free moaA riboswitch and its ion-dependent folding.
Journal of inorganic biochemistry May, 2023 | Pubmed ID: 36774787
Organometallic Pillarplexes That Bind DNA 4-Way Holliday Junctions and Forks.
Journal of the American Chemical Society Jun, 2023 | Pubmed ID: 37318835
Group II Introns: Highly Structured yet Dynamic.
Chimia Apr, 2023 | Pubmed ID: 38047803
Identification of HDV-like theta ribozymes involved in tRNA-based recoding of gut bacteriophages.
Nature communications Feb, 2024 | Pubmed ID: 38378708
From Enigma to Revelation: Unravelling Biological Functions of Ubiquitous Small Ribozymes.
Chimia Apr, 2024 | Pubmed ID: 38676609
Reply to: On the statistical foundation of a recent single molecule FRET benchmark.
Nature communications Apr, 2024 | Pubmed ID: 38688911
FRET-guided modeling of nucleic acids.
Nucleic acids research Jul, 2024 | Pubmed ID: 38869063
Corrin Ring Modifications Reveal the Chemical and Spatial Requirements for the B-btuB Riboswitch Interaction.
Chemistry (Weinheim an der Bergstrasse, Germany) Sep, 2024 | Pubmed ID: 38922714
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