Division of Obstetrics and Gynecology,
Department of Clinical Science,
Intervention and Technology,
Division of Obstetrics and Gynecology, Department of Clinical Science, Intervention and Technology
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Reporter zebrafish: endocrine disruption meets estrogen signaling.
Endocrinology Jul, 2011 | Pubmed ID: 21697454
A single dose of enterolactone activates estrogen signaling and regulates expression of circadian clock genes in mice.
The Journal of nutrition Sep, 2011 | Pubmed ID: 21753063
Biosensors paving the way to understanding the interaction between cadmium and the estrogen receptor alpha.
PloS one , 2011 | Pubmed ID: 21829690
Cadmium-induced effects on cellular signaling pathways in the liver of transgenic estrogen reporter mice.
Toxicological sciences : an official journal of the Society of Toxicology May, 2012 | Pubmed ID: 22314386
Clonal culturing of human embryonic stem cells on laminin-521/E-cadherin matrix in defined and xeno-free environment.
Nature communications , 2014 | Pubmed ID: 24463987
Spider silk for xeno-free long-term self-renewal and differentiation of human pluripotent stem cells.
Biomaterials Oct, 2014 | Pubmed ID: 25043502
Cadmium at nanomolar concentrations activates Raf-MEK-ERK1/2 MAPKs signaling via EGFR in human cancer cell lines.
Chemico-biological interactions Apr, 2015 | Pubmed ID: 25744307
Emerging role of PLAG1 as a regulator of growth and reproduction.
The Journal of endocrinology Feb, 2016 | Pubmed ID: 26577933
Human embryonic stem cells.
Best practice & research. Clinical obstetrics & gynaecology Feb, 2016 | Pubmed ID: 26602389
From pure compounds to complex exposure: Effects of dietary cadmium and lignans on estrogen, epidermal growth factor receptor, and mitogen activated protein kinase signaling in vivo.
Toxicology letters Jun, 2016 | Pubmed ID: 27108949
The Hydroxysteroid (17β) Dehydrogenase Family Gene HSD17B12 Is Involved in the Prostaglandin Synthesis Pathway, the Ovarian Function, and Regulation of Fertility.
Endocrinology Oct, 2016 | Pubmed ID: 27490311
Resveratrol supports and alpha-naphthoflavone disrupts growth of human ovarian follicles in an in vitro tissue culture model.
Toxicology and applied pharmacology Jan, 2018 | Pubmed ID: 29146461
Concentrations of perfluoroalkyl substances (PFASs) in human embryonic and fetal organs from first, second, and third trimester pregnancies.
Environment international Mar, 2019 | Pubmed ID: 30684806
Gestational exposure to an epidemiologically defined mixture of phthalates leads to gonadal dysfunction in mouse offspring of both sexes.
Scientific reports Apr, 2019 | Pubmed ID: 31015488
Retinoic acid signaling in ovarian folliculogenesis and steroidogenesis.
Reproductive toxicology (Elmsford, N.Y.) Aug, 2019 | Pubmed ID: 31059772
Pleomorphic Adenoma Gene 1 Is Needed For Timely Zygotic Genome Activation and Early Embryo Development.
Scientific reports Jun, 2019 | Pubmed ID: 31182756
Impact of first-line cancer treatment on the follicle quality in cryopreserved ovarian samples from girls and young women.
Human reproduction (Oxford, England) Sep, 2019 | Pubmed ID: 31411325
In-utero stress and mode of conception: impact on regulation of imprinted genes, fetal development and future health.
Human reproduction update Nov, 2019 | Pubmed ID: 31633761
Human induced pluripotent stem cells from two azoospermic patients with Klinefelter syndrome show similar X chromosome inactivation behavior to female pluripotent stem cells.
Human reproduction (Oxford, England) Nov, 2019 | Pubmed ID: 31743397
Persistent environmental endocrine-disrupting chemicals in ovarian follicular fluid and fertilization treatment outcome in women.
Upsala journal of medical sciences May, 2020 | Pubmed ID: 32093529
Single-cell analysis of human ovarian cortex identifies distinct cell populations but no oogonial stem cells.
Nature communications Mar, 2020 | Pubmed ID: 32123174
Reply: Impact of first-line cancer treatment on follicle quality in cryopreserved ovarian samples.
Human reproduction (Oxford, England) May, 2020 | Pubmed ID: 32281630
Safeguarding Female Reproductive Health against Endocrine Disrupting Chemicals-The FREIA Project.
International journal of molecular sciences May, 2020 | Pubmed ID: 32370092
Persistent organic pollutants, pre-pregnancy use of combined oral contraceptives, age, and time-to-pregnancy in the SELMA cohort.
Environmental health : a global access science source Jun, 2020 | Pubmed ID: 32539770
Putative adverse outcome pathways for female reproductive disorders to improve testing and regulation of chemicals.
Archives of toxicology Oct, 2020 | Pubmed ID: 32638039
Transcriptome analysis of the epididymis from Plag1 deficient mice suggests dysregulation of sperm maturation and extracellular matrix genes.
Developmental dynamics : an official publication of the American Association of Anatomists Dec, 2020 | Pubmed ID: 32959928
Fertility Preservation for Prepubertal Patients at Risk of Infertility: Present Status and Future Perspectives.
Hormone research in paediatrics , 2020 | Pubmed ID: 33887724
Persistent organic pollutants and the size of ovarian reserve in reproductive-aged women.
Environment international Oct, 2021 | Pubmed ID: 33945905
Phthalates, ovarian function and fertility in adulthood.
Best practice & research. Clinical endocrinology & metabolism Sep, 2021 | Pubmed ID: 34238683
Mixtures of persistent organic pollutants are found in vital organs of late gestation human fetuses.
Chemosphere Nov, 2021 | Pubmed ID: 34467953
A Pragmatic Approach to Adverse Outcome Pathway Development and Evaluation.
Toxicological sciences : an official journal of the Society of Toxicology Nov, 2021 | Pubmed ID: 34534351
Suspect and non-target screening of ovarian follicular fluid and serum - identification of anthropogenic chemicals and investigation of their association to fertility.
Environmental science. Processes & impacts Oct, 2021 | Pubmed ID: 34581388
Perfluorooctane sulfonate (PFOS) exposure of bovine oocytes affects early embryonic development at human-relevant levels in an in vitro model.
Toxicology Dec, 2021 | Pubmed ID: 34762985
Follicular fluid and blood levels of persistent organic pollutants and reproductive outcomes among women undergoing assisted reproductive technologies.
Environmental research May, 2022 | Pubmed ID: 34973191
From cohorts to molecules: Adverse impacts of endocrine disrupting mixtures.
Science (New York, N.Y.) Feb, 2022 | Pubmed ID: 35175820
Bovine oocyte exposure to perfluorohexane sulfonate (PFHxS) induces phenotypic, transcriptomic, and DNA methylation changes in resulting embryos in vitro.
Reproductive toxicology (Elmsford, N.Y.) Apr, 2022 | Pubmed ID: 35219833
In vivo and in vitro postovulatory aging: when time works against oocyte quality?
Journal of assisted reproduction and genetics Apr, 2022 | Pubmed ID: 35312936
Overexpression of Human Estrogen Biosynthetic Enzyme Hydroxysteroid (17beta) Dehydrogenase Type 1 Induces Adenomyosis-like Phenotype in Transgenic Mice.
International journal of molecular sciences Apr, 2022 | Pubmed ID: 35563206
Development and application of a health-based framework for informing regulatory action in relation to exposure of microplastic particles in California drinking water.
Microplastics and nanoplastics , 2022 | Pubmed ID: 35634037
Toxicity Assessment of Resveratrol Liposomes-in-Hydrogel Delivery System by EpiVaginal Tissue Model.
Pharmaceutics Jun, 2022 | Pubmed ID: 35745867
AOP key event relationship report: Linking decreased androgen receptor activation with decreased granulosa cell proliferation of gonadotropin-independent follicles.
Reproductive toxicology (Elmsford, N.Y.) Sep, 2022 | Pubmed ID: 35868514
Endocrine disrupting chemicals interfere with decidualization of human primary endometrial stromal cells .
Frontiers in endocrinology , 2022 | Pubmed ID: 36060944
Spatial Proteomics for Further Exploration of Missing Proteins: A Case Study of the Ovary.
Journal of proteome research Apr, 2023 | Pubmed ID: 36108145
The Continued Absence of Functional Germline Stem Cells in Adult Ovaries.
Stem cells (Dayton, Ohio) Mar, 2023 | Pubmed ID: 36153824
Association between chemical mixtures and female fertility in women undergoing assisted reproduction in Sweden and Estonia.
Environmental research Jan, 2023 | Pubmed ID: 36181890
In Reply: Revisiting Claims of the Continued Absence of Functional Germline Stem Cells in Adult Ovaries.
Stem cells (Dayton, Ohio) Mar, 2023 | Pubmed ID: 36472571
Identification of biomarkers and outcomes of endocrine disruption in human ovarian cortex using In Vitro Models.
Toxicology Feb, 2023 | Pubmed ID: 36621641
Identification of phthalate mixture exposure targets in the human and mouse ovary in vitro.
Reproductive toxicology (Elmsford, N.Y.) Aug, 2023 | Pubmed ID: 37160244
Quantitative analysis of ovarian surface photographs as a tool for assessment of chemical effects on folliculogenesis and ovulation in rats.
Reproductive toxicology (Elmsford, N.Y.) Aug, 2023 | Pubmed ID: 37268149
Associations between lifestyle factors and levels of per- and polyfluoroalkyl substances (PFASs), phthalates and parabens in follicular fluid in women undergoing fertility treatment.
Journal of exposure science & environmental epidemiology Sep, 2023 | Pubmed ID: 37481638
Reference standards for follicular density in ovarian cortex from birth to sexual maturity.
Reproductive biomedicine online Oct, 2023 | Pubmed ID: 37603956
Ambient black carbon particles in human ovarian tissue and follicular fluid.
Environment international Sep, 2023 | Pubmed ID: 37603992
Pregnancy-related maternal physiological adaptations and fetal chemical exposure.
Molecular and cellular endocrinology Dec, 2023 | Pubmed ID: 37683908
Comparison of female rat reproductive effects of pubertal adult exposure to known endocrine disruptors.
Frontiers in endocrinology , 2023 | Pubmed ID: 37854179
Transcriptomics and Spatial Proteomics for Discovery and Validation of Missing Proteins in the Human Ovary.
Journal of proteome research Jan, 2024 | Pubmed ID: 38085962
The Upper Reproductive System Microbiome: Evidence beyond the Uterus.
Seminars in reproductive medicine Sep, 2023 | Pubmed ID: 38320577
Investigating the impact of vitrification on bovine ovarian tissue morphology, follicle survival, and transcriptomic signature.
Journal of assisted reproduction and genetics Apr, 2024 | Pubmed ID: 38358432
Endocrine disrupting chemicals are a threat to hormone health: a commentary on behalf of the ESE.
Nature reviews. Endocrinology Apr, 2024 | Pubmed ID: 38388677
Exposure to the phthalate metabolite MEHP impacts survival and growth of human ovarian follicles in vitro.
Toxicology Jun, 2024 | Pubmed ID: 38685446
Persistent organic pollutants dysregulate energy homeostasis in human ovaries in vitro.
Environment international May, 2024 | Pubmed ID: 38701644
The profile of steroid hormones in human fetal and adult ovaries.
Reproductive biology and endocrinology : RB&E May, 2024 | Pubmed ID: 38778396
Effects of chemical activation versus fragmentation on human ovarian tissue and follicle growth in culture.
Human reproduction open , 2024 | Pubmed ID: 38803550
Enhanced identification of endocrine disruptors through integration of science-based regulatory practices and innovative methodologies: The MERLON Project.
Open research Europe , 2024 | Pubmed ID: 38883262
Epidemiologically relevant phthalates affect human endometrial cells in vitro through cell specific gene expression changes related to the cytoskeleton and mitochondria.
Reproductive toxicology (Elmsford, N.Y.) Sep, 2024 | Pubmed ID: 38992643
In-depth analysis of transcriptomes in ovarian cortical follicles from children and adults reveals interfollicular heterogeneity.
Nature communications Aug, 2024 | Pubmed ID: 39168975
Reduced ovarian cholesterol and steroid biosynthesis along with increased inflammation are associated with high DEHP metabolite levels in human ovarian follicular fluids.
Environment international Sep, 2024 | Pubmed ID: 39173238
AOP Report: An Upstream Network for Reduced Androgen Signaling Leading to Altered Gene Expression of Androgen Receptor-Responsive Genes in Target Tissues.
Environmental toxicology and chemistry Nov, 2024 | Pubmed ID: 39206816
Phthalate monoesters affect membrane fluidity and cell-cell contacts in endometrial stromal adherent cell lines and spheroids.
Reproductive toxicology (Elmsford, N.Y.) Oct, 2024 | Pubmed ID: 39396682
Jasmin Hassan1,2,
Pauliina Damdimopoulou1,2,
Atte Lahtinen3,4,
Kirsi Jahnukainen5,6,
Katri Knuus7,
Ganesh Acharya1,
Richelle D. Björvang1,8,9
1Division of Obstetrics and Gynecology, Department of Clinical Science, Intervention and Technology, Karolinska Institutet,
2Department of Gynecology and Reproductive Medicine, Karolinska University Hospital,
3Applied Tumor Genomics Research Program, Faculty of Medicine, University of Helsinki,
4Department of Medical and Clinical Genetics, Medicum, Faculty of Medicine, University of Helsinki,
5Children's Hospital, Pediatric Research Centre, University of Helsinki and Helsinki University Hospital,
6NORDFERTIL Research Lab Stockholm, Department of Women's, and Children's Health, Karolinska Institutet, and Karolinska University Hospital,
7Department of Obstetrics and Gynecology, Helsinki University Hospital, University of Helsinki,
8Department of Cell and Molecular Biology, Uppsala University,
9Department of Women's and Children's Health, Uppsala University
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