bilateral-common-carotid-artery-occlusion-as-an-adequate

Bilateral Common Carotid Artery Occlusion as an Adequate Preconditioning Stimulus to Induce Early Ischemic Tolerance to Focal Cerebral Ischemia

There is accumulating evidence, that ischemic preconditioning - a non-damaging ischemic challenge to the brain - confers a transient protection to a ...

Charité - Universitätsmedizin Berlin, Germany

[Regeneration, following partial hepatectomy, of liver chronically damaged by diethylnitrosamine].

[R&eacute;g&eacute;n&eacute;ration, apr&egrave;s une h&eacute;patectomie partielle, du foie, chroniquement endommag&eacute; par di&eacute;thylnitrosamine].

[Rigenerazione, dopo epatectomia parziale, del fegato cronicamente danneggiata da diethylnitrosamine].

[On regeneration of the DANA-damaged liver following partial hepatectomy].

[Sur la r&eacute;g&eacute;n&eacute;ration de l&#39;h&eacute;patectomie partielle suivante du foie endommag&eacute; par DANA].

[Sulla rigenerazione del danneggiato DANA fegato seguente parziale epatectomia].

[On proliferative activity of the diethylnitrosamine-damaged liver following partial hepatectomy].

[Sur l&#39;activit&eacute; prolif&eacute;rative de l&#39;h&eacute;patectomie partielle suivante foie endommag&eacute; di&eacute;thylnitrosamine].

[Sull&#39;attivit&agrave; proliferativa il danneggiato diethylnitrosamine fegato seguente parziale epatectomia].

The purpose of the study was to test a newly developed, MR-compatible, liquid nitrogen-cooled cryoprobe. The probe has an outer diameter of 3.5 mm and was specifically developed for percutaneous, MR-guided, interstitial cryotherapy. The probe was inserted percutaneously into the livers of 10 rabbits. The cryotherapy procedure was monitored with a surface coil in a 1.5 Tesla magnet using a gradient echo sequence. Follow-up examinations were performed 3 and 7 days after the freezing procedure using T1- and T2-weighted spin echo sequences. At 7 days the animals were sacrificed and the cryolesions were examined histologically. The cryoprobe enabled artifact-free MR imaging of the "iceball" formation during freezing of the rabbit liver. After 1 min of freezing, the iceball at the tip of the probe showed an average maximum diameter of 10.8 mm. No bleeding complications were observed during or after the freezing procedure. Histologic examination 7 days after cryotherapy confirmed that the liver lesions were the same size as had been predicted by the images of the acute iceball. This new, percutaneously inserted, MR-compatible, liquid-nitrogen cooled cryoprobe allows accurate, artifact-free MR imaging of interstitial cryotherapy.

MR-guided interstitial cryotherapy of the liver with a novel, nitrogen-cooled cryoprobe.

L&#39;&eacute;tude visait &agrave; tester une cryosonde nouvellement mis au point, M. compatible, liquide de refroidi &agrave; l&#39;azote. La sonde a un diam&egrave;tre ext&eacute;rieur de 3,5 mm et a &eacute;t&eacute; sp&eacute;cialement d&eacute;velopp&eacute;e pour la cryoth&eacute;rapie percutan&eacute;e, guid&eacute;e, interstitiel. La sonde a &eacute;t&eacute; ins&eacute;r&eacute;e par voie percutan&eacute;e, dans les foies de 10 lapins. La proc&eacute;dure de la cryoth&eacute;rapie a &eacute;t&eacute; suivie avec une bobine de surface dans un aimant de 1,5 Tesla en utilisant une s&eacute;quence d&#39;&eacute;cho de gradient. Les examens de suivi ont &eacute;t&eacute; r&eacute;alis&eacute;s 3 et 7 jours apr&egrave;s la proc&eacute;dure de cong&eacute;lation &agrave; l&#39;aide de s&eacute;quences d&#39;&eacute;cho de spin pond&eacute;r&eacute;es en T1 et en T2. &Agrave; 7 jours, les animaux ont &eacute;t&eacute; sacrifi&eacute;s et les cryolesions ont &eacute;t&eacute; examin&eacute;es histologiquement. La CRYOSONDE activ&eacute; sans artefact M. imagerie de la formation &laquo; qui &raquo; g&egrave;le le foie de lapin. Apr&egrave;s 1 min de la cong&eacute;lation, la qui, &agrave; la pointe de la sonde ont montr&eacute; un diam&egrave;tre maximal moyen de 10,8 mm. Aucune complication h&eacute;morragique ont &eacute;t&eacute; observ&eacute;es pendant ou apr&egrave;s la proc&eacute;dure de cong&eacute;lation. 7 Jours apr&egrave;s que la cryoth&eacute;rapie a confirm&eacute; que les l&eacute;sions du foie &eacute;taient de la m&ecirc;me taille comme avait &eacute;t&eacute; pr&eacute;dit par les images de l&#39;aigu&euml; qui l&#39;examen histologique. Cette nouvelle, par voie percutan&eacute;e ins&eacute;r&eacute;, M.-compatible, azote liquide cryosonde refroidi permet M. pr&eacute;cis, sans artefact d&#39;imagerie de cryoth&eacute;rapie interstitielle.

Guid&eacute;e par Monsieur interstitielle cryoth&eacute;rapie du foie avec une cryosonde roman, refroidi &agrave; l&#39;azote.

Lo scopo dello studio era quello di testare un cryoprobe recentemente sviluppato, signor-compatibile, liquido raffreddato ad azoto. La sonda ha un diametro esterno di 3,5 mm ed &egrave; stato specificamente sviluppata per la crioterapia percutanea, guidata dal signor, interstiziale. La sonda era inserita percutaneo i fegati di 10 conigli. La procedura di crioterapia &egrave; stata monitorata con una bobina di superficie in un magnete di 1,5 Tesla utilizzando una sequenza di eco di pendenza. Gli esami di follow-up sono stati eseguiti 3 e 7 giorni dopo la procedura di congelamento con T1 e T2-pesate spin echo sequenze. A 7 giorni gli animali venivano sacrificati e il cryolesions sono stati esaminati istologicamente. Il cryoprobe abilitato Signor artefatto-free imaging della formazione &quot;iceball&quot; durante il congelamento il fegato di coniglio. Dopo 1 minuto di congelamento, iceball presso la punta della sonda ha mostrato un diametro massimo medio di 10,8 mm. No complicanze emorragiche sono state osservate durante o dopo la procedura di congelamento. Esame istologico 7 giorni dopo la crioterapia ha confermato che le lesioni epatiche avevano le stesse dimensioni, come era stato previsto dalle immagini del iceball acuta. Questo nuovo, percutaneo inserito, signor-compatibile, azoto liquido refrigerato cryoprobe permette Signor accurato, privo di artefatti di imaging della crioterapia interstiziale.

Guidati dal signor crioterapia interstiziale del fegato con un cryoprobe romanzo, raffreddato ad azoto.

[Criochirurgia interstiziale minimamente invasiva con orientamento MRI: possibilit&agrave; di applicazione clinica e ricerca in vivo].

[Minimally invasive interstitial cryosurgery with MRI guidance: possibilities for in vivo research and clinical application].

[Mini-invasive cryochirurgie interstitielle avec orientation MRI: possibilit&eacute;s de recherche in vivo et application clinique].

To test radial k-space scanning by MR fluoroscopy to guide and control MR-guided interstitial cryotherapy of the healthy pig brain.

[Experimental MRI-controlled cryotherapy of the brain with almost real-time imaging by radial k-space scanning].

Pour tester le k-espace radial le balayage par Monsieur fluoroscopie pour guider et contr&ocirc;ler la cryoth&eacute;rapie interstitielle guid&eacute;e du cerveau de porc sain.

[Exp&eacute;rimental contr&ocirc;l&eacute; par MRI cryoth&eacute;rapie du cerveau avec une imagerie en temps quasi r&eacute;el par k-espace radial balayage].

Per testare il k-spazio radiale scansione dal signor fluoroscopia per guidare e controllare guidato dal signor crioterapia interstiziale del cervello sano maiale.

[Sperimentale controllato MRI crioterapia del cervello con quasi in tempo reale immagini di k-spazio radiale scansione].

To evaluate the imaging capabilities of ultrasound (US), computed tomography (CT), and magnetic resonance imaging (MRI) in monitoring interstitial cryotherapy and to compare them with visual control.

Imaging of interstitial cryotherapy--an in vitro comparison of ultrasound, computed tomography, and magnetic resonance imaging.

Afin d&#39;&eacute;valuer les capacit&eacute;s d&#39;imagerie de l&#39;&eacute;chographie (US), calcul&eacute;e par tomodensitom&eacute;trie (TDM) et l&#39;imagerie par r&eacute;sonance magn&eacute;tique (IRM) dans la surveillance interstitielle cryoth&eacute;rapie et de les comparer avec contr&ocirc;le visuel.

Imagerie de la cryoth&eacute;rapie interstitielle--une comparaison in vitro de l&#39;&eacute;chographie, la tomodensitom&eacute;trie et imagerie par r&eacute;sonance magn&eacute;tique.

Per valutare la capacit&agrave; di imaging di ultrasuoni (US), computato tomografia computerizzata (TC) e risonanza magnetica (MRI) nel monitoraggio della crioterapia interstiziale e confrontarli con un controllo visivo.

Imaging della crioterapia interstiziale - un confronto in vitro dell&#39;ecografia, la tomografia computerizzata e risonanza magnetica.

Hyperthermal ablation techniques such as laser or RF ablation require dedicated heat-sensitive MR imaging sequences for monitoring MR imaging--guided interventions. Because cryotherapy does not have these limitations, the purpose of this study was to evaluate the feasibility of MR imaging--guided percutaneous cryotherapy of the brain.

Experimental MR imaging-guided interstitial cryotherapy of the brain.

Ablation hyperthermales techniques tels que le laser ou l&#39;ablation RF n&eacute;cessitent d&eacute;di&eacute; thermosensibles IRM s&eacute;quences pour la surveillance de M. imagerie--guid&eacute; des interventions. Parce que la cryoth&eacute;rapie n&#39;a pas ces limites, le but de cette &eacute;tude &eacute;tait d&#39;&eacute;valuer la faisabilit&eacute; de M. imagerie--guid&eacute; cryoth&eacute;rapie percutan&eacute;e du cerveau.

Experimental Monsieur guid&eacute;e par imagerie interstitielle cryoth&eacute;rapie du cerveau.

Ablazione ipertermali tecniche come il laser o l&#39;ablazione con radiofrequenza richiedono dedicato sensibili al calore MR imaging sequenze per il monitoraggio di MR imaging - guidate interventi. Perch&eacute; la crioterapia non hanno queste limitazioni, lo scopo di questo studio era di valutare la fattibilit&agrave; di MR imaging - guidate crioterapia percutanea del cervello.

Sperimentale MR imaging-guidate interstiziale crioterapia del cervello.

Motorcycle helmet laws: every surgeon's responsibility.

Lois de casque de moto : la responsabilit&eacute; de chaque chirurgien.

Moto leggi casco: responsabilit&agrave; di ogni chirurgo.

Venous thromboembolic events (VTE) are potentially preventable causes of morbidity and mortality after injury. We hypothesized that the current clinical incidence of VTE is relatively low and that VTE risk factors could be identified.

Thromboembolism after trauma: an analysis of 1602 episodes from the American College of Surgeons National Trauma Data Bank.

Thromboembolie veineuse (TEV) est potentiellement &eacute;vitables causes de morbidit&eacute; et de mortalit&eacute; apr&egrave;s une blessure. Nous avons &eacute;mis l&#39;hypoth&egrave;se que l&#39;incidence clinique actuelle d&#39;&eacute;v&eacute;nements thromboemboliques veineux est relativement faible et que les facteurs de risque de TEV pouvaient &ecirc;tre identifi&eacute;es.

Thromboembolies apr&egrave;s un traumatisme : une analyse des &eacute;pisodes de 1602 de l&#39;American College de chirurgiens traumatisme Banque nationale de donn&eacute;es.

Eventi tromboembolici venosi (VTE) sono potenzialmente prevenibile cause di morbilit&agrave; e mortalit&agrave; dopo l&#39;infortunio. Abbiamo ipotizzato che l&#39;attuale incidenza clinica di TEV &egrave; relativamente bassa e che potrebbe essere identificati fattori di rischio di TEV.

Tromboembolia dopo un trauma: un&#39;analisi di 1602 episodi da American College di chirurghi Trauma dati Banca nazionale.

Vascular birthmarks are the most common birthmarks encountered in newborns. Many dermatologists are unfamiliar with the normal physiologic changes that affect and alter their appearance during early infancy. In this article we discuss normal newborn hemodynamic/neurovascular physiology and the associated clinical findings in neonatal skin. The physiologic anemia of infancy and its resultant effects on skin color and the appearance of vascular birthmarks are detailed. Finally, the pitfalls and obstacles to early diagnosis of vascular birthmarks and the subtle differences between them are reviewed, as are the challenges in assessing response to early pulsed dye laser treatment in the context of the changing vascular physiology.

Physiologic changes in vascular birthmarks during early infancy: Mechanisms and clinical implications.

Taches de naissance vasculaires sont les taches de naissance plus courantes rencontr&eacute;es chez le nouveau-n&eacute;. Beaucoup de dermatologues ne connaissent pas les changements physiologiques normaux qui affectent et modifient leur apparence au cours de la petite enfance. Dans cet article, nous discutons physiologie normale d&#39;h&eacute;modynamique/neurovasculaire nouveau-n&eacute; et les r&eacute;sultats cliniques associ&eacute;s &agrave; peau n&eacute;onatale. L&#39;an&eacute;mie physiologique de la petite enfance et de ses effets qui en r&eacute;sultent sur la couleur de la peau et l&#39;apparition de taches de naissance vasculaires sont d&eacute;taill&eacute;es. Enfin, les pi&egrave;ges et les obstacles au diagnostic pr&eacute;coce de la vasculaires birthmarks et les subtiles diff&eacute;rences entre eux sont l&#39;objet, comme le sont les d&eacute;fis pour &eacute;valuer la r&eacute;ponse au traitement laser &agrave; colorant puls&eacute; pr&eacute;coce dans le contexte de l&#39;&eacute;volution de la physiologie vasculaire.

Les changements physiologiques dans des taches de naissance vasculaires au cours de la petite enfance : m&eacute;canismes et implications cliniques.

Voglie vascolari sono le voglie pi&ugrave; comuni incontrati nei neonati. Molti dermatologi non hanno familiarit&agrave; con i normali cambiamenti fisiologici che possono influenzare e alterano la loro comparsa durante la prima infanzia. In questo articolo discutiamo neonato emodinamica/neurovascolare normale fisiologia e i rilievi clinici associati in pelle neonatale. L&#39;anemia fisiologica dell&#39;infanzia e dei suoi effetti risultante sul colore della pelle e la comparsa di voglie vascolari sono dettagliati. Infine, le insidie e gli ostacoli alla diagnosi precoce delle voglie vascolari e le sottili differenze tra loro sono rivisti, come sono le sfide nel valutare la risposta all&#39;inizio del trattamento laser dye pulsato nel contesto della modifica fisiologia vascolare.

Article	Year
[Regeneration, following partial hepatectomy, of liver chronically damaged by diethylnitrosamine]. Zeitschrift fÃ¼r Naturforschung. Teil B: Chemie, Biochemie, Biophysik, Biologie\| PubMed ID: 4386052	1968
[On regeneration of the DANA-damaged liver following partial hepatectomy]. Die Naturwissenschaften\| PubMed ID: 5588752	1967
[On proliferative activity of the diethylnitrosamine-damaged liver following partial hepatectomy]. Die Naturwissenschaften\| PubMed ID: 5626210	1967
MR-guided interstitial cryotherapy of the liver with a novel, nitrogen-cooled cryoprobe. Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine\| PubMed ID: 9498590	1998
[Minimally invasive interstitial cryosurgery with MRI guidance: possibilities for in vivo research and clinical application]. Biomedizinische Technik. Biomedical engineering\| PubMed ID: 9859233	1998
[Experimental MRI-controlled cryotherapy of the brain with almost real-time imaging by radial k-space scanning]. RÃ¶Fo : Fortschritte auf dem Gebiete der RÃ¶ntgenstrahlen und der Nuklearmedizin\| PubMed ID: 10101365	1999
Imaging of interstitial cryotherapy--an in vitro comparison of ultrasound, computed tomography, and magnetic resonance imaging. Cryobiology\| PubMed ID: 10328915	1999
Experimental MR imaging-guided interstitial cryotherapy of the brain. AJNR. American journal of neuroradiology\| PubMed ID: 11237963	2001
Motorcycle helmet laws: every surgeon's responsibility. Journal of the American College of Surgeons\| PubMed ID: 15275883	2004
Thromboembolism after trauma: an analysis of 1602 episodes from the American College of Surgeons National Trauma Data Bank. Annals of surgery\| PubMed ID: 15319720	2004
Physiologic changes in vascular birthmarks during early infancy: Mechanisms and clinical implications. Journal of the American Academy of Dermatology\| PubMed ID: 19167781	2009
Multiple primary cutaneous melanomas in Li-Fraumeni syndrome. Archives of dermatology\| PubMed ID: 21339461	2011

Lukas Julius Speetzen

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