Center for Immunology and Inflammatory Diseases,
and Pulmonary and Critical Care Unit,
Center for Immunology and Inflammatory Diseases, and Pulmonary and Critical Care Unit
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Quantitative impact of thymic selection on Foxp3+ and Foxp3- subsets of self-peptide/MHC class II-specific CD4+ T cells.
Proceedings of the National Academy of Sciences of the United States of America Aug, 2011 | Pubmed ID: 21873213
Robust antigen specific th17 T cell response to group A Streptococcus is dependent on IL-6 and intranasal route of infection.
PLoS pathogens Sep, 2011 | Pubmed ID: 21966268
CARMA1 is necessary for optimal T cell responses in a murine model of allergic asthma.
Journal of immunology (Baltimore, Md. : 1950) Dec, 2011 | Pubmed ID: 22075698
Enhancing humoral responses to a malaria antigen with nanoparticle vaccines that expand Tfh cells and promote germinal center induction.
Proceedings of the National Academy of Sciences of the United States of America Jan, 2012 | Pubmed ID: 22247289
The role of naive T cell precursor frequency and recruitment in dictating immune response magnitude.
Journal of immunology (Baltimore, Md. : 1950) May, 2012 | Pubmed ID: 22517866
Detection of an autoreactive T-cell population within the polyclonal repertoire that undergoes distinct autoimmune regulator (Aire)-mediated selection.
Proceedings of the National Academy of Sciences of the United States of America May, 2012 | Pubmed ID: 22552229
CXCR3 chemokine receptor-ligand interactions in the lymph node optimize CD4+ T helper 1 cell differentiation.
Immunity Dec, 2012 | Pubmed ID: 23123063
Adjuvant formulation structure and composition are critical for the development of an effective vaccine against tuberculosis.
Journal of controlled release : official journal of the Controlled Release Society Nov, 2013 | Pubmed ID: 23933525
Cutting edge: type 1 diabetes occurs despite robust anergy among endogenous insulin-specific CD4 T cells in NOD mice.
Journal of immunology (Baltimore, Md. : 1950) Nov, 2013 | Pubmed ID: 24123682
A dual TLR agonist adjuvant enhances the immunogenicity and protective efficacy of the tuberculosis vaccine antigen ID93.
PloS one , 2014 | Pubmed ID: 24404140
T cell receptor cross-reactivity between similar foreign and self peptides influences naive cell population size and autoimmunity.
Immunity Jan, 2015 | Pubmed ID: 25601203
The human T-cell repertoire grows up.
Immunology and cell biology Aug, 2015 | Pubmed ID: 25939281
Characterization of a New Epitope of IRBP That Induces Moderate to Severe Uveoretinitis in Mice With H-2b Haplotype.
Investigative ophthalmology & visual science Aug, 2015 | Pubmed ID: 26284549
CD4+ T Cell Tolerance to Tissue-Restricted Self Antigens Is Mediated by Antigen-Specific Regulatory T Cells Rather Than Deletion.
Immunity Nov, 2015 | Pubmed ID: 26572061
A Wave of Regulatory T Cells into Neonatal Skin Mediates Tolerance to Commensal Microbes.
Immunity Nov, 2015 | Pubmed ID: 26588783
Interleukin-2-Dependent Allergen-Specific Tissue-Resident Memory Cells Drive Asthma.
Immunity Jan, 2016 | Pubmed ID: 26750312
Delayed Cytotoxic T Lymphocyte-Associated Protein 4-Immunoglobulin Treatment Reverses Ongoing Alloantibody Responses and Rescues Allografts From Acute Rejection.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons Aug, 2016 | Pubmed ID: 26928966
LYN- and AIRE-mediated tolerance checkpoint defects synergize to trigger organ-specific autoimmunity.
The Journal of clinical investigation Oct, 2016 | Pubmed ID: 27571405
Allergic asthma is distinguished by sensitivity of allergen-specific CD4+ T cells and airway structural cells to type 2 inflammation.
Science translational medicine Oct, 2016 | Pubmed ID: 27708065
Selective Induction of Homeostatic Th17 Cells in the Murine Intestine by Cholera Toxin Interacting with the Microbiota.
Journal of immunology (Baltimore, Md. : 1950) Jul, 2017 | Pubmed ID: 28539431
Epitope mapping and kinetics of CD4 T cell immunity to pneumonia virus of mice in the C57BL/6 strain.
Scientific reports Jun, 2017 | Pubmed ID: 28615708
Generation of Allergen-Specific Tetramers for a Murine Model of Airway Inflammation.
Methods in molecular biology (Clifton, N.J.) , 2018 | Pubmed ID: 29956152
Distinct Graft-Specific TCR Avidity Profiles during Acute Rejection and Tolerance.
Cell reports Aug, 2018 | Pubmed ID: 30134172
Differential IL-2 expression defines developmental fates of follicular versus nonfollicular helper T cells.
Science (New York, N.Y.) Sep, 2018 | Pubmed ID: 30213884
induces intestinal adaptive immune responses during homeostasis.
Science (New York, N.Y.) Jun, 2019 | Pubmed ID: 31221858
Context-Dependent Role for T-bet in T Follicular Helper Differentiation and Germinal Center Function following Viral Infection.
Cell reports Aug, 2019 | Pubmed ID: 31412245
Opposing peripheral fates of tissue-restricted self antigen-specific conventional and regulatory CD4 T cells.
European journal of immunology Jan, 2020 | Pubmed ID: 31580477
Natural Tr1-like cells do not confer long-term tolerogenic memory.
eLife 10, 2019 | Pubmed ID: 31603425
DOCK2 Sets the Threshold for Entry into the Virtual Memory CD8 T Cell Compartment by Negatively Regulating Tonic TCR Triggering.
Journal of immunology (Baltimore, Md. : 1950) Jan, 2020 | Pubmed ID: 31740487
In vivo engineering of lymphocytes after systemic exosome-associated AAV delivery.
Scientific reports Mar, 2020 | Pubmed ID: 32161326
Systemic lupus erythematosus favors the generation of IL-17 producing double negative T cells.
Nature communications Jun, 2020 | Pubmed ID: 32503973
Differential expression of tissue-restricted antigens among mTEC is associated with distinct autoreactive T cell fates.
Nature communications Jul, 2020 | Pubmed ID: 32709894
Interleukin-33 activates regulatory T cells to suppress innate γδ T cell responses in the lung.
Nature immunology Nov, 2020 | Pubmed ID: 32989331
Identification of antigen-specific TCR sequences based on biological and statistical enrichment in unselected individuals.
JCI insight Jul, 2021 | Pubmed ID: 34032640
Rejection of benign melanocytic nevi by nevus-resident CD4 T cells.
Science advances Jun, 2021 | Pubmed ID: 34162549
SARS-CoV-2 epitope-specific CD4 memory T cell responses across COVID-19 disease severity and antibody durability.
Science immunology Jul, 2022 | Pubmed ID: 35857584
A conserved Bacteroidetes antigen induces anti-inflammatory intestinal T lymphocytes.
Science (New York, N.Y.) Aug, 2022 | Pubmed ID: 35926021
Combined Regulatory T-Lymphocyte and IL-2 Treatment Is Safe, Tolerable, and Biologically Active for 1 Year in Persons With Amyotrophic Lateral Sclerosis.
Neurology(R) neuroimmunology & neuroinflammation Nov, 2022 | Pubmed ID: 36038262
The CD4 T cell response to a commensal-derived epitope transitions from a tolerant to an inflammatory state in Crohn's disease.
Immunity Oct, 2022 | Pubmed ID: 36115338
IRF4 expression by lung dendritic cells drives acute but not Trm cell-dependent memory Th2 responses.
JCI insight Nov, 2022 | Pubmed ID: 36194494
Tumor-associated macrophages expressing the transcription factor IRF8 promote T cell exhaustion in cancer.
Immunity Nov, 2022 | Pubmed ID: 36288724
Autoimmunity to synovial extracellular matrix proteins in patients with postinfectious Lyme arthritis.
The Journal of clinical investigation Sep, 2023 | Pubmed ID: 37471146
Lung injury induces a polarized immune response by self-antigen-specific CD4 Foxp3 regulatory T cells.
Cell reports Aug, 2023 | Pubmed ID: 37471223
Mapping the T cell repertoire to a complex gut bacterial community.
Nature Sep, 2023 | Pubmed ID: 37587342
Identification of mouse CD4 T cell epitopes in SARS-CoV-2 BA.1 spike and nucleocapsid for use in peptide:MHCII tetramers.
bioRxiv : the preprint server for biology Nov, 2023 | Pubmed ID: 38014059
Identification of mouse CD4 T cell epitopes in SARS-CoV-2 BA.1 spike and nucleocapsid for use in peptide:MHCII tetramers.
Frontiers in immunology , 2024 | Pubmed ID: 38529279
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