James J. Moon

Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital and Harvard Medical School

Affiliated withMassachusetts General Hospital and Harvard Medical School Massachusetts General Hospital Harvard Medical School

Research Area

Immunology and Infection

Biography

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JoVE Journal Publications

Article Total : 2	Year
Publication title	2012
Publication title	2024

Other Publications

Article	Year
Quantitative impact of thymic selection on Foxp3+ and Foxp3- subsets of self-peptide/MHC class II-specific CD4+ T cells. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 21873213	2011
Robust antigen specific th17 T cell response to group A Streptococcus is dependent on IL-6 and intranasal route of infection. PLoS pathogens\| PubMed ID: 21966268	2011
CARMA1 is necessary for optimal T cell responses in a murine model of allergic asthma. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 22075698	2011
Enhancing humoral responses to a malaria antigen with nanoparticle vaccines that expand Tfh cells and promote germinal center induction. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 22247289	2012
The role of naive T cell precursor frequency and recruitment in dictating immune response magnitude. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 22517866	2012
Detection of an autoreactive T-cell population within the polyclonal repertoire that undergoes distinct autoimmune regulator (Aire)-mediated selection. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 22552229	2012
CXCR3 chemokine receptor-ligand interactions in the lymph node optimize CD4+ T helper 1 cell differentiation. Immunity\| PubMed ID: 23123063	2012
Adjuvant formulation structure and composition are critical for the development of an effective vaccine against tuberculosis. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 23933525	2013
Cutting edge: type 1 diabetes occurs despite robust anergy among endogenous insulin-specific CD4 T cells in NOD mice. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 24123682	2013
A dual TLR agonist adjuvant enhances the immunogenicity and protective efficacy of the tuberculosis vaccine antigen ID93. PloS one\| PubMed ID: 24404140	2014
T cell receptor cross-reactivity between similar foreign and self peptides influences naive cell population size and autoimmunity. Immunity\| PubMed ID: 25601203	2015
The human T-cell repertoire grows up. Immunology and cell biology\| PubMed ID: 25939281	2015
Characterization of a New Epitope of IRBP That Induces Moderate to Severe Uveoretinitis in Mice With H-2b Haplotype. Investigative ophthalmology & visual science\| PubMed ID: 26284549	2015
CD4+ T Cell Tolerance to Tissue-Restricted Self Antigens Is Mediated by Antigen-Specific Regulatory T Cells Rather Than Deletion. Immunity\| PubMed ID: 26572061	2015
A Wave of Regulatory T Cells into Neonatal Skin Mediates Tolerance to Commensal Microbes. Immunity\| PubMed ID: 26588783	2015
Interleukin-2-Dependent Allergen-Specific Tissue-Resident Memory Cells Drive Asthma. Immunity\| PubMed ID: 26750312	2016
Delayed Cytotoxic T Lymphocyte-Associated Protein 4-Immunoglobulin Treatment Reverses Ongoing Alloantibody Responses and Rescues Allografts From Acute Rejection. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons\| PubMed ID: 26928966	2016
LYN- and AIRE-mediated tolerance checkpoint defects synergize to trigger organ-specific autoimmunity. The Journal of clinical investigation\| PubMed ID: 27571405	2016
Allergic asthma is distinguished by sensitivity of allergen-specific CD4+ T cells and airway structural cells to type 2 inflammation. Science translational medicine\| PubMed ID: 27708065	2016
Selective Induction of Homeostatic Th17 Cells in the Murine Intestine by Cholera Toxin Interacting with the Microbiota. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 28539431	2017
Epitope mapping and kinetics of CD4 T cell immunity to pneumonia virus of mice in the C57BL/6 strain. Scientific reports\| PubMed ID: 28615708	2017
Generation of Allergen-Specific Tetramers for a Murine Model of Airway Inflammation. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 29956152	2018
Distinct Graft-Specific TCR Avidity Profiles during Acute Rejection and Tolerance. Cell reports\| PubMed ID: 30134172	2018
Differential IL-2 expression defines developmental fates of follicular versus nonfollicular helper T cells. Science (New York, N.Y.)\| PubMed ID: 30213884	2018
induces intestinal adaptive immune responses during homeostasis. Science (New York, N.Y.)\| PubMed ID: 31221858	2019
Context-Dependent Role for T-bet in T Follicular Helper Differentiation and Germinal Center Function following Viral Infection. Cell reports\| PubMed ID: 31412245	2019
Opposing peripheral fates of tissue-restricted self antigen-specific conventional and regulatory CD4 T cells. European journal of immunology\| PubMed ID: 31580477	2020
Natural Tr1-like cells do not confer long-term tolerogenic memory. eLife\| PubMed ID: 31603425	2019
DOCK2 Sets the Threshold for Entry into the Virtual Memory CD8 T Cell Compartment by Negatively Regulating Tonic TCR Triggering. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 31740487	2020
In vivo engineering of lymphocytes after systemic exosome-associated AAV delivery. Scientific reports\| PubMed ID: 32161326	2020
Systemic lupus erythematosus favors the generation of IL-17 producing double negative T cells. Nature communications\| PubMed ID: 32503973	2020
Differential expression of tissue-restricted antigens among mTEC is associated with distinct autoreactive T cell fates. Nature communications\| PubMed ID: 32709894	2020
Interleukin-33 activates regulatory T cells to suppress innate γδ T cell responses in the lung. Nature immunology\| PubMed ID: 32989331	2020
Identification of antigen-specific TCR sequences based on biological and statistical enrichment in unselected individuals. JCI insight\| PubMed ID: 34032640	2021
Rejection of benign melanocytic nevi by nevus-resident CD4 T cells. Science advances\| PubMed ID: 34162549	2021
SARS-CoV-2 epitope-specific CD4 memory T cell responses across COVID-19 disease severity and antibody durability. Science immunology\| PubMed ID: 35857584	2022
A conserved Bacteroidetes antigen induces anti-inflammatory intestinal T lymphocytes. Science (New York, N.Y.)\| PubMed ID: 35926021	2022
Combined Regulatory T-Lymphocyte and IL-2 Treatment Is Safe, Tolerable, and Biologically Active for 1 Year in Persons With Amyotrophic Lateral Sclerosis. Neurology(R) neuroimmunology & neuroinflammation\| PubMed ID: 36038262	2022
The CD4 T cell response to a commensal-derived epitope transitions from a tolerant to an inflammatory state in Crohn's disease. Immunity\| PubMed ID: 36115338	2022
IRF4 expression by lung dendritic cells drives acute but not Trm cell-dependent memory Th2 responses. JCI insight\| PubMed ID: 36194494	2022
Tumor-associated macrophages expressing the transcription factor IRF8 promote T cell exhaustion in cancer. Immunity\| PubMed ID: 36288724	2022
Autoimmunity to synovial extracellular matrix proteins in patients with postinfectious Lyme arthritis. The Journal of clinical investigation\| PubMed ID: 37471146	2023
Lung injury induces a polarized immune response by self-antigen-specific CD4 Foxp3 regulatory T cells. Cell reports\| PubMed ID: 37471223	2023
Mapping the T cell repertoire to a complex gut bacterial community. Nature\| PubMed ID: 37587342	2023
Identification of mouse CD4 T cell epitopes in SARS-CoV-2 BA.1 spike and nucleocapsid for use in peptide:MHCII tetramers. bioRxiv : the preprint server for biology\| PubMed ID: 38014059	2023
Identification of mouse CD4 T cell epitopes in SARS-CoV-2 BA.1 spike and nucleocapsid for use in peptide:MHCII tetramers. Frontiers in immunology\| PubMed ID: 38529279	2024