Thomas Powles

St Bartholomew's Cancer Institute, Queen Mary University of London

Affiliated withQueen Mary University of London Queen Mary University of London

Research Area

Medicine

Biography

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JoVE Journal Publications

Article Total : 1	Year
Publication title	2013

Other Publications

Article	Year
Effect of haemopoietic growth factors on cancer cell lines and their role in chemosensitivity. Oncogene\| PubMed ID: 14647427	2004
Erythropoietin to treat anaemia in patients with head and neck cancer. Lancet\| PubMed ID: 14724015	2004
HIV and the risk of lung cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 15051794	2004
Cannabis-induced cytotoxicity in leukemic cell lines: the role of the cannabinoid receptors and the MAPK pathway. Blood\| PubMed ID: 15454482	2005
Antiapoptotic effect of growth factors in leukemia. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 15659515	2005
The changing presentation of germ cell tumours of the testis between 1983 and 2002. BJU international\| PubMed ID: 15892800	2005
Hepatocellular cancer in HIV-infected individuals: tomorrow's problem? Expert review of anticancer therapy\| PubMed ID: 17134360	2006
Does PET imaging have a role in renal cancers after all? The lancet oncology\| PubMed ID: 17395099	2007
Non-AIDS-defining cancers in people with HIV infection: a sleeping giant? Journal of HIV therapy\| PubMed ID: 17580500	2006
A comparison of the platinum analogues in bladder cancer cell lines. Urologia internationalis\| PubMed ID: 17627172	2007
Neoadjuvant therapy followed by prostatectomy for clinically localized prostate cancer. Cancer\| PubMed ID: 17941029	2007
Germ-cell tumors. The New England journal of medicine\| PubMed ID: 17960020	2007
HIV-associated Castleman's disease: from case reports to evidence. Journal of HIV therapy\| PubMed ID: 17962792	2007
Prostate cancer in HIV-positive individuals: what we know and what we don't. Journal of HIV therapy\| PubMed ID: 17962795	2007
Malignant germ cell tumours in the elderly: a histopathological review of 50 cases in men aged 60 years or over. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc\| PubMed ID: 17975539	2008
Novel agents for muscle-invasive and advanced urothelial cancer. BJU international\| PubMed ID: 18005203	2008
Hepatocellular carcinoma, human immunodeficiency virus and viral hepatitis in the HAART era. World journal of gastroenterology : WJG\| PubMed ID: 18350596	2008
The efficacy and safety of weekly vinorelbine in relapsed malignant pleural mesothelioma. Lung cancer (Amsterdam, Netherlands)\| PubMed ID: 18486273	2009
Enhancing the in vitro cytotoxic activity of Delta9-tetrahydrocannabinol in leukemic cells through a combinatorial approach. Leukemia & lymphoma\| PubMed ID: 18608861	2008
Human immunodeficiency virus--associated renal cell carcinoma: a transatlantic case series. Clinical genitourinary cancer\| PubMed ID: 18824430	2008
Smoke and mirrors: HIV-related lung cancer. Current opinion in oncology\| PubMed ID: 19106655	2008
Highly active antiretroviral therapy and the incidence of non-AIDS-defining cancers in people with HIV infection. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 19114688	2009
The relative activity of cisplatin, oxaliplatin and satraplatin in testicular germ cell tumour sensitive and resistant cell lines. Cancer chemotherapy and pharmacology\| PubMed ID: 19263053	2009
Amplification of epidermal growth factor receptor gene in renal cell carcinoma. European journal of cancer (Oxford, England : 1990)\| PubMed ID: 20167476	2010
The association of CCND1 overexpression and cisplatin resistance in testicular germ cell tumors and other cancers. The American journal of pathology\| PubMed ID: 20395447	2010
A validated prognostic index predicting response to dexamethasone and diethylstilbestrol in castrate-resistant prostate cancer. Cancer\| PubMed ID: 20564115	2010
The application of the National Institute of Clinical Excellence guidelines for treatment of metastatic renal cell carcinoma in the United Kingdom: friend or foe? BJU international\| PubMed ID: 20576026	2010
Elevated LDH predicts poor outcome of recurrent germ cell tumours treated with dose dense chemotherapy. European journal of cancer (Oxford, England : 1990)\| PubMed ID: 20709529	2010
Integrating surgery with targeted therapies for renal cell carcinoma: current evidence and ongoing trials. European urology\| PubMed ID: 20828919	2010
A synergistic interaction between lapatinib and chemotherapy agents in a panel of cell lines is due to the inhibition of the efflux pump BCRP. Molecular cancer therapeutics\| PubMed ID: 20889729	2010
Prognostic factors in patients with metastatic germ cell tumors who experienced treatment failure with cisplatin-based first-line chemotherapy. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 20956623	2010
The effect of sunitinib on immune subsets in metastatic clear cell renal cancer. Urologia internationalis\| PubMed ID: 20975250	2011
Castration refractory prostate cancer: cinderella finally comes to the ball. Onkologie\| PubMed ID: 21124035	2010
The efficacy and safety of irinotecan cisplatin and mitomycin chemotherapy in sunitinib pre-treated metastatic clear cell renal cancer. OncoTargets and therapy\| PubMed ID: 21127750	2008
Efficacy and toxicity of sunitinib in patients with metastatic renal cell carcinoma with severe renal impairment or on haemodialysis. BJU international\| PubMed ID: 21244613	2011
Conventional-dose versus high-dose chemotherapy as first salvage treatment in male patients with metastatic germ cell tumors: evidence from a large international database. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 21444870	2011
What can molecular pathology contribute to the management of renal cell carcinoma? Nature reviews. Urology\| PubMed ID: 21487387	2011
Stage I nonseminomatous germ cell tumor of the testis: more questions than answers? Hematology/oncology clinics of North America\| PubMed ID: 21570606	2011
The outcome of patients treated with sunitinib prior to planned nephrectomy in metastatic clear cell renal cancer. European urology\| PubMed ID: 21612860	2011
Sequential FDG-PET/CT as a biomarker of response to Sunitinib in metastatic clear cell renal cancer. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 21742806	2011
Is high dose therapy superior to conventional dose therapy as initial treatment for relapsed germ cell tumors? The TIGER Trial. Journal of Cancer\| PubMed ID: 21750688	2011
Sequential therapy in metastatic renal cell carcinoma: what comes next? Medical oncology (Northwood, London, England)\| PubMed ID: 21964814	2012
Whole blood stem cell re-infusion and escalated dose melphalan in castration-resistant prostate cancer: a phase 1 study. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 22392912	2012
Second-line therapy after VEGF targeted therapy in metastatic renal cancer: a law of diminishing returns. Clinical genitourinary cancer\| PubMed ID: 22608779	2012
Performing cytoreductive nephrectomy following targeted sunitinib therapy for metastatic renal cell carcinoma: a surgical perspective. Urologia internationalis\| PubMed ID: 22614181	2012
Accelerated methotrexate, vinblastine, doxorubicin, and cisplatin (AMVAC) as neoadjuvant chemotherapy for patients with muscle-invasive transitional cell carcinoma of the bladder. Cancer\| PubMed ID: 22614698	2012
Treatment of relapsed/refractory germ cell tumours: an equipoise between conventional and high dose therapy. Current treatment options in oncology\| PubMed ID: 22623055	2012
A systematic review of neoadjuvant and adjuvant chemotherapy for muscle-invasive bladder cancer. European urology\| PubMed ID: 22677572	2012
Neoadjuvant and adjuvant treatment of renal cell carcinoma. Expert review of anticancer therapy\| PubMed ID: 22716493	2012
An indirect comparison of the toxicity of sunitinib and pazopanib in metastatic clear cell renal cancer. European journal of cancer (Oxford, England : 1990)\| PubMed ID: 22766517	2012
Contrasting effects of sunitinib within in vivo models of metastasis. Angiogenesis\| PubMed ID: 22843200	2012
Management of favorable-risk patients with metastatic renal cell carcinoma: when to start and when to stop targeted therapy. Clinical genitourinary cancer\| PubMed ID: 22939100	2012
Carboplatin AUC 10 for IGCCCG good prognosis metastatic seminoma. Acta oncologica (Stockholm, Sweden)\| PubMed ID: 22943385	2012
The hazards of cross comparing the drug toxicity results from different trials in metastatic renal cancer: In response to a letter from Dr. CatalÃ¡-LÃ³pez. European journal of cancer (Oxford, England : 1990)\| PubMed ID: 23138000	2012
Probability of downsizing primary tumors of renal cell carcinoma by targeted therapies is related to size at presentation. Urology\| PubMed ID: 23153934	2013
Gemcitabine, Cisplatin, and Sunitinib for Metastatic Urothelial Carcinoma and as Preoperative Therapy for Muscle-Invasive Bladder Cancer. Clinical genitourinary cancer\| PubMed ID: 23228446	2012
The conundrum of clinical trials in adult germ-cell tumours. The lancet oncology\| PubMed ID: 23276363	2013