St Bartholomew's Cancer Institute,
Experimental Cancer Medicine Centre,
St Bartholomew's Cancer Institute, Experimental Cancer Medicine Centre
Thomas Powles has not added Biography.
If you are Thomas Powles and would like to personalize this page please email our Author Liaison for assistance.
Effect of haemopoietic growth factors on cancer cell lines and their role in chemosensitivity.
Oncogene Jan, 2004 | Pubmed ID: 14647427
Erythropoietin to treat anaemia in patients with head and neck cancer.
Lancet Jan, 2004 | Pubmed ID: 14724015
HIV and the risk of lung cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology Apr, 2004 | Pubmed ID: 15051794
Cannabis-induced cytotoxicity in leukemic cell lines: the role of the cannabinoid receptors and the MAPK pathway.
Blood Feb, 2005 | Pubmed ID: 15454482
Antiapoptotic effect of growth factors in leukemia.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology Jan, 2005 | Pubmed ID: 15659515
The changing presentation of germ cell tumours of the testis between 1983 and 2002.
BJU international Jun, 2005 | Pubmed ID: 15892800
Hepatocellular cancer in HIV-infected individuals: tomorrow's problem?
Expert review of anticancer therapy Nov, 2006 | Pubmed ID: 17134360
Does PET imaging have a role in renal cancers after all?
The lancet oncology Apr, 2007 | Pubmed ID: 17395099
Non-AIDS-defining cancers in people with HIV infection: a sleeping giant?
Journal of HIV therapy Sep, 2006 | Pubmed ID: 17580500
A comparison of the platinum analogues in bladder cancer cell lines.
Urologia internationalis , 2007 | Pubmed ID: 17627172
Neoadjuvant therapy followed by prostatectomy for clinically localized prostate cancer.
Cancer Dec, 2007 | Pubmed ID: 17941029
Germ-cell tumors.
The New England journal of medicine Oct, 2007 | Pubmed ID: 17960020
HIV-associated Castleman's disease: from case reports to evidence.
Journal of HIV therapy Sep, 2007 | Pubmed ID: 17962792
Prostate cancer in HIV-positive individuals: what we know and what we don't.
Journal of HIV therapy Sep, 2007 | Pubmed ID: 17962795
Malignant germ cell tumours in the elderly: a histopathological review of 50 cases in men aged 60 years or over.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc Jan, 2008 | Pubmed ID: 17975539
Novel agents for muscle-invasive and advanced urothelial cancer.
BJU international Apr, 2008 | Pubmed ID: 18005203
Hepatocellular carcinoma, human immunodeficiency virus and viral hepatitis in the HAART era.
World journal of gastroenterology : WJG Mar, 2008 | Pubmed ID: 18350596
The efficacy and safety of weekly vinorelbine in relapsed malignant pleural mesothelioma.
Lung cancer (Amsterdam, Netherlands) Jan, 2009 | Pubmed ID: 18486273
Enhancing the in vitro cytotoxic activity of Delta9-tetrahydrocannabinol in leukemic cells through a combinatorial approach.
Leukemia & lymphoma Sep, 2008 | Pubmed ID: 18608861
Human immunodeficiency virus--associated renal cell carcinoma: a transatlantic case series.
Clinical genitourinary cancer Sep, 2008 | Pubmed ID: 18824430
Smoke and mirrors: HIV-related lung cancer.
Current opinion in oncology Sep, 2008 | Pubmed ID: 19106655
Highly active antiretroviral therapy and the incidence of non-AIDS-defining cancers in people with HIV infection.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology Feb, 2009 | Pubmed ID: 19114688
The relative activity of cisplatin, oxaliplatin and satraplatin in testicular germ cell tumour sensitive and resistant cell lines.
Cancer chemotherapy and pharmacology Oct, 2009 | Pubmed ID: 19263053
Amplification of epidermal growth factor receptor gene in renal cell carcinoma.
European journal of cancer (Oxford, England : 1990) Mar, 2010 | Pubmed ID: 20167476
The association of CCND1 overexpression and cisplatin resistance in testicular germ cell tumors and other cancers.
The American journal of pathology Jun, 2010 | Pubmed ID: 20395447
A validated prognostic index predicting response to dexamethasone and diethylstilbestrol in castrate-resistant prostate cancer.
Cancer Aug, 2010 | Pubmed ID: 20564115
The application of the National Institute of Clinical Excellence guidelines for treatment of metastatic renal cell carcinoma in the United Kingdom: friend or foe?
BJU international Aug, 2010 | Pubmed ID: 20576026
Elevated LDH predicts poor outcome of recurrent germ cell tumours treated with dose dense chemotherapy.
European journal of cancer (Oxford, England : 1990) Nov, 2010 | Pubmed ID: 20709529
Integrating surgery with targeted therapies for renal cell carcinoma: current evidence and ongoing trials.
European urology Dec, 2010 | Pubmed ID: 20828919
A synergistic interaction between lapatinib and chemotherapy agents in a panel of cell lines is due to the inhibition of the efflux pump BCRP.
Molecular cancer therapeutics Dec, 2010 | Pubmed ID: 20889729
Prognostic factors in patients with metastatic germ cell tumors who experienced treatment failure with cisplatin-based first-line chemotherapy.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology Nov, 2010 | Pubmed ID: 20956623
The effect of sunitinib on immune subsets in metastatic clear cell renal cancer.
Urologia internationalis , 2011 | Pubmed ID: 20975250
Castration refractory prostate cancer: cinderella finally comes to the ball.
Onkologie , 2010 | Pubmed ID: 21124035
The efficacy and safety of irinotecan cisplatin and mitomycin chemotherapy in sunitinib pre-treated metastatic clear cell renal cancer.
OncoTargets and therapy , 2008 | Pubmed ID: 21127750
Efficacy and toxicity of sunitinib in patients with metastatic renal cell carcinoma with severe renal impairment or on haemodialysis.
BJU international Oct, 2011 | Pubmed ID: 21244613
Conventional-dose versus high-dose chemotherapy as first salvage treatment in male patients with metastatic germ cell tumors: evidence from a large international database.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology Jun, 2011 | Pubmed ID: 21444870
What can molecular pathology contribute to the management of renal cell carcinoma?
Nature reviews. Urology May, 2011 | Pubmed ID: 21487387
Stage I nonseminomatous germ cell tumor of the testis: more questions than answers?
Hematology/oncology clinics of North America Jun, 2011 | Pubmed ID: 21570606
The outcome of patients treated with sunitinib prior to planned nephrectomy in metastatic clear cell renal cancer.
European urology Sep, 2011 | Pubmed ID: 21612860
Sequential FDG-PET/CT as a biomarker of response to Sunitinib in metastatic clear cell renal cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research Sep, 2011 | Pubmed ID: 21742806
Is high dose therapy superior to conventional dose therapy as initial treatment for relapsed germ cell tumors? The TIGER Trial.
Journal of Cancer , 2011 | Pubmed ID: 21750688
Sequential therapy in metastatic renal cell carcinoma: what comes next?
Medical oncology (Northwood, London, England) Sep, 2012 | Pubmed ID: 21964814
Whole blood stem cell re-infusion and escalated dose melphalan in castration-resistant prostate cancer: a phase 1 study.
Clinical cancer research : an official journal of the American Association for Cancer Research Mar, 2012 | Pubmed ID: 22392912
Second-line therapy after VEGF targeted therapy in metastatic renal cancer: a law of diminishing returns.
Clinical genitourinary cancer Jun, 2012 | Pubmed ID: 22608779
Performing cytoreductive nephrectomy following targeted sunitinib therapy for metastatic renal cell carcinoma: a surgical perspective.
Urologia internationalis , 2012 | Pubmed ID: 22614181
Accelerated methotrexate, vinblastine, doxorubicin, and cisplatin (AMVAC) as neoadjuvant chemotherapy for patients with muscle-invasive transitional cell carcinoma of the bladder.
Cancer Aug, 2012 | Pubmed ID: 22614698
Treatment of relapsed/refractory germ cell tumours: an equipoise between conventional and high dose therapy.
Current treatment options in oncology Jun, 2012 | Pubmed ID: 22623055
A systematic review of neoadjuvant and adjuvant chemotherapy for muscle-invasive bladder cancer.
European urology Sep, 2012 | Pubmed ID: 22677572
Neoadjuvant and adjuvant treatment of renal cell carcinoma.
Expert review of anticancer therapy Jun, 2012 | Pubmed ID: 22716493
An indirect comparison of the toxicity of sunitinib and pazopanib in metastatic clear cell renal cancer.
European journal of cancer (Oxford, England : 1990) Nov, 2012 | Pubmed ID: 22766517
Contrasting effects of sunitinib within in vivo models of metastasis.
Angiogenesis Dec, 2012 | Pubmed ID: 22843200
Management of favorable-risk patients with metastatic renal cell carcinoma: when to start and when to stop targeted therapy.
Clinical genitourinary cancer Dec, 2012 | Pubmed ID: 22939100
Carboplatin AUC 10 for IGCCCG good prognosis metastatic seminoma.
Acta oncologica (Stockholm, Sweden) Sep, 2012 | Pubmed ID: 22943385
The hazards of cross comparing the drug toxicity results from different trials in metastatic renal cancer: In response to a letter from Dr. Catalá-López.
European journal of cancer (Oxford, England : 1990) Nov, 2012 | Pubmed ID: 23138000
Probability of downsizing primary tumors of renal cell carcinoma by targeted therapies is related to size at presentation.
Urology Jan, 2013 | Pubmed ID: 23153934
Gemcitabine, Cisplatin, and Sunitinib for Metastatic Urothelial Carcinoma and as Preoperative Therapy for Muscle-Invasive Bladder Cancer.
Clinical genitourinary cancer Dec, 2012 | Pubmed ID: 23228446
The conundrum of clinical trials in adult germ-cell tumours.
The lancet oncology Jan, 2013 | Pubmed ID: 23276363
Fiach C. O'Mahony1,
Jyoti Nanda1,
Alexander Laird1,
Peter Mullen2,
Helen Caldwell3,
Ian M. Overton4,
Lel Eory4,
Marie O'Donnell1,5,
Dana Faratian6,
Thomas Powles7,
David J. Harrison1,2,
Grant D. Stewart1
1Edinburgh Urological Cancer Group, University of Edinburgh,
2School of Medicine, University of St Andrews,
3Division of Pathology, University of Edinburgh,
4MRC Human Genetics Unit, MRC IGMM, University of Edinburgh,
5Department of Pathology, Western General Hospital,
6Breakthrough Breast Cancer Research Unit, University of Edinburgh,
7St Bartholomew's Cancer Institute, Experimental Cancer Medicine Centre, Queen Mary University of London
SOBRE A JoVE
Copyright © 2024 MyJoVE Corporation. Todos os direitos reservados