Genome Stability Laboratory,
Oncology Axis,
Genome Stability Laboratory, Oncology Axis
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Role of mammalian RAD51L2 (RAD51C) in recombination and genetic stability.
The Journal of biological chemistry May, 2002 | Pubmed ID: 11912211
XRCC3 and Rad51 modulate replication fork progression on damaged vertebrate chromosomes.
Molecular cell Apr, 2003 | Pubmed ID: 12718895
RAD51C is required for Holliday junction processing in mammalian cells.
Science (New York, N.Y.) Jan, 2004 | Pubmed ID: 14716019
Chromatin remodeling and the maintenance of genome integrity.
Biochimica et biophysica acta Mar, 2004 | Pubmed ID: 15020056
Conformational changes modulate the activity of human RAD51 protein.
Journal of molecular biology Apr, 2004 | Pubmed ID: 15033353
Direct interaction of FANCD2 with BRCA2 in DNA damage response pathways.
Human molecular genetics Jun, 2004 | Pubmed ID: 15115758
Exploring the multiple facets of the meiotic recombinase Dmc1.
BioEssays : news and reviews in molecular, cellular and developmental biology Nov, 2004 | Pubmed ID: 15499584
Arginine methylation of MRE11 by PRMT1 is required for DNA damage checkpoint control.
Genes & development Mar, 2005 | Pubmed ID: 15741314
The Hop2 and Mnd1 proteins act in concert with Rad51 and Dmc1 in meiotic recombination.
Nature structural & molecular biology May, 2005 | Pubmed ID: 15834424
Fission yeast rad51 and dmc1, two efficient DNA recombinases forming helical nucleoprotein filaments.
Molecular and cellular biology Jun, 2005 | Pubmed ID: 15899844
Methylation of MRE11 regulates its nuclear compartmentalization.
Cell cycle (Georgetown, Tex.) Jul, 2005 | Pubmed ID: 15970667
[A new role for arginine methylation in DNA repair].
Médecine sciences : M/S Jun-Jul, 2005 | Pubmed ID: 15985195
Targeting poly(ADP-ribosyl)ation: a promising approach in cancer therapy.
Trends in molecular medicine Oct, 2005 | Pubmed ID: 16154385
The transcriptional histone acetyltransferase cofactor TRRAP associates with the MRN repair complex and plays a role in DNA double-strand break repair.
Molecular and cellular biology Jan, 2006 | Pubmed ID: 16382133
Interplay between human DNA repair proteins at a unique double-strand break in vivo.
The EMBO journal Jan, 2006 | Pubmed ID: 16395335
Twists and turns in the function of DNA damage signaling and repair proteins by post-translational modifications.
DNA repair May, 2007 | Pubmed ID: 17258515
Stimulation of fission yeast and mouse Hop2-Mnd1 of the Dmc1 and Rad51 recombinases.
Nucleic acids research , 2007 | Pubmed ID: 17426123
PARP1-dependent kinetics of recruitment of MRE11 and NBS1 proteins to multiple DNA damage sites.
The Journal of biological chemistry Jan, 2008 | Pubmed ID: 18025084
A glycine-arginine domain in control of the human MRE11 DNA repair protein.
Molecular and cellular biology May, 2008 | Pubmed ID: 18285453
Functional and structural basis for a bacteriophage homolog of human RAD52.
Current biology : CB Aug, 2008 | Pubmed ID: 18656357
Recovery of deficient homologous recombination in Brca2-depleted mouse cells by wild-type Rad51 expression.
DNA repair Feb, 2009 | Pubmed ID: 18992372
The Werner syndrome protein affects the expression of genes involved in adipogenesis and inflammation in addition to cell cycle and DNA damage responses.
Cell cycle (Georgetown, Tex.) Jul, 2009 | Pubmed ID: 19502800
MRE11-RAD50-NBS1 is a critical regulator of FANCD2 stability and function during DNA double-strand break repair.
The EMBO journal Aug, 2009 | Pubmed ID: 19609304
Structure and function of phage p2 ORF34(p2), a new type of single-stranded DNA binding protein.
Molecular microbiology Sep, 2009 | Pubmed ID: 19719513
FANCD2: A DNA binding protein regulated by MRE11-RAD50-NBS1.
Cell cycle (Georgetown, Tex.) Jan, 2010 | Pubmed ID: 20023418
Deciphering the function of lactococcal phage ul36 Sak domains.
Journal of structural biology Jun, 2010 | Pubmed ID: 20036743
Cooperation of breast cancer proteins PALB2 and piccolo BRCA2 in stimulating homologous recombination.
Nature structural & molecular biology Oct, 2010 | Pubmed ID: 20871615
Proteome-wide identification of WRN-interacting proteins in untreated and nuclease-treated samples.
Journal of proteome research Mar, 2011 | Pubmed ID: 21210717
Irinotecan and DNA-PKcs inhibitors synergize in killing of colon cancer cells.
Investigational new drugs Jun, 2012 | Pubmed ID: 21221710
A key role for poly(ADP-ribose) polymerase 3 in ectodermal specification and neural crest development.
PloS one , 2011 | Pubmed ID: 21264220
Lactococcal phage p2 ORF35-Sak3 is an ATPase involved in DNA recombination and AbiK mechanism.
Molecular microbiology Apr, 2011 | Pubmed ID: 21276096
The effect of a DNA repair gene on cellular invasiveness: XRCC3 over-expression in breast cancer cells.
PloS one , 2011 | Pubmed ID: 21283680
Partners apart: Smc6-independent DNA binding activity of Smc5 on single-strand DNA.
Cell cycle (Georgetown, Tex.) Apr, 2011 | Pubmed ID: 21415594
The MRE11 GAR motif regulates DNA double-strand break processing and ATR activation.
Cell research Feb, 2012 | Pubmed ID: 21826105
ChAM, a novel motif that mediates PALB2 intrinsic chromatin binding and facilitates DNA repair.
EMBO reports Feb, 2012 | Pubmed ID: 22193777
The microRNA pathway controls germ cell proliferation and differentiation in C. elegans.
Cell research Jun, 2012 | Pubmed ID: 22370633
CBX4-mediated SUMO modification regulates BMI1 recruitment at sites of DNA damage.
Nucleic acids research Jul, 2012 | Pubmed ID: 22402492
Interactions between BRCA2 and RAD51 for promoting homologous recombination in Leishmania infantum.
Nucleic acids research Aug, 2012 | Pubmed ID: 22505581
A requirement for polymerized actin in DNA double-strand break repair.
Nucleus (Austin, Tex.) Jul, 2012 | Pubmed ID: 22688650
Synthesis, biological evaluation, and structure-activity relationships of novel substituted N-phenyl ureidobenzenesulfonate derivatives blocking cell cycle progression in S-phase and inducing DNA double-strand breaks.
Journal of medicinal chemistry Jul, 2012 | Pubmed ID: 22694057
PARP activation regulates the RNA-binding protein NONO in the DNA damage response to DNA double-strand breaks.
Nucleic acids research Nov, 2012 | Pubmed ID: 22941645
PALB2 self-interaction controls homologous recombination.
Nucleic acids research Nov, 2012 | Pubmed ID: 22941656
The RAD51 paralogs ensure cellular protection against mitotic defects and aneuploidy.
Journal of cell science Jan, 2013 | Pubmed ID: 23108668
Reprogramming cellular events by poly(ADP-ribose)-binding proteins.
Molecular aspects of medicine Dec, 2013 | Pubmed ID: 23268355
Detection of the HIV-1 minus-strand-encoded antisense protein and its association with autophagy.
Journal of virology May, 2013 | Pubmed ID: 23427159
Fanconi anemia group J helicase and MRE11 nuclease interact to facilitate the DNA damage response.
Molecular and cellular biology Jun, 2013 | Pubmed ID: 23530059
[Functions of PALB2 and BRCA2 tumor suppressors in DNA double-strand break repair].
Médecine sciences : M/S Mar, 2013 | Pubmed ID: 23544385
Coupling of Homologous Recombination and the Checkpoint by ATR.
Molecular cell Jan, 2017 | Pubmed ID: 28089683
The Tumor Suppressor PALB2: Inside Out.
Trends in biochemical sciences 03, 2019 | Pubmed ID: 30638972
Poly(ADP-ribose) polymerase-1 antagonizes DNA resection at double-strand breaks.
Nature communications 07, 2019 | Pubmed ID: 31273204
Limiting the DNA Double-Strand Break Resectosome for Genome Protection.
Trends in biochemical sciences 09, 2020 | Pubmed ID: 32513599
Animal models of Fanconi anemia: A developmental and therapeutic perspective on a multifaceted disease.
Seminars in cell & developmental biology May, 2021 | Pubmed ID: 33558144
Addressing the dark matter of gene therapy: technical and ethical barriers to clinical application.
Human genetics Apr, 2021 | Pubmed ID: 33834266
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