Mirella L Meyer-Ficca

Department of Animal Biology and Center for Animal Transgenesis and Germ Cell Research

University of Pennsylvania

BIOGRAPHY

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PUBLICATIONS

Human poly(ADP-ribose) glycohydrolase (PARG) gene and the common promoter sequence it shares with inner mitochondrial membrane translocase 23 (TIM23).

Gene Sep, 2003 | Pubmed ID: 14527731

Plasmid-based generation of recombinant coxsackievirus B3 particles carrying capsid gene replacement replicons.

Virus research Aug, 2004 | Pubmed ID: 15177888

Human poly(ADP-ribose) glycohydrolase is expressed in alternative splice variants yielding isoforms that localize to different cell compartments.

Experimental cell research Jul, 2004 | Pubmed ID: 15212953

Depletion of the 110-kilodalton isoform of poly(ADP-ribose) glycohydrolase increases sensitivity to genotoxic and endotoxic stress in mice.

Molecular and cellular biology Aug, 2004 | Pubmed ID: 15282315

Comparative analysis of inducible expression systems in transient transfection studies.

Analytical biochemistry Nov, 2004 | Pubmed ID: 15464949

Poly(ADP-ribose) polymerases: managing genome stability.

The international journal of biochemistry & cell biology May, 2005 | Pubmed ID: 15743666

Poly(ADP-ribosyl)ation during chromatin remodeling steps in rat spermiogenesis.

Chromosoma May, 2005 | Pubmed ID: 15838619

Altered poly(ADP-ribose) metabolism impairs cellular responses to genotoxic stress in a hypomorphic mutant of poly(ADP-ribose) glycohydrolase.

Experimental cell research Mar, 2007 | Pubmed ID: 17276427

Two small enzyme isoforms mediate mammalian mitochondrial poly(ADP-ribose) glycohydrolase (PARG) activity.

Experimental cell research Aug, 2007 | Pubmed ID: 17509564

Disruption of poly(ADP-ribose) homeostasis affects spermiogenesis and sperm chromatin integrity in mice.

Biology of reproduction Jul, 2009 | Pubmed ID: 19264700

A specific isoform of poly(ADP-ribose) glycohydrolase is targeted to the mitochondrial matrix by a N-terminal mitochondrial targeting sequence.

Experimental cell research Dec, 2009 | Pubmed ID: 19389396

Poly(ADP-ribose) metabolism is essential for proper nucleoprotein exchange during mouse spermiogenesis.

Biology of reproduction Feb, 2011 | Pubmed ID: 20881315

Poly(ADP-ribose) polymerases PARP1 and PARP2 modulate topoisomerase II beta (TOP2B) function during chromatin condensation in mouse spermiogenesis.

Biology of reproduction May, 2011 | Pubmed ID: 21228215

Genetic approaches to targeting multiple PARP genes in a mammalian genome.

Methods in molecular biology (Clifton, N.J.) , 2011 | Pubmed ID: 21870271

Alteration of poly(ADP-ribose) metabolism affects murine sperm nuclear architecture by impairing pericentric heterochromatin condensation.

Chromosoma Aug, 2013 | Pubmed ID: 23729169

INSTITUTIONS

University of Pennsylvania

JOVE ARTICLES

Separation of Spermatogenic Cell Types Using STA-PUT Velocity Sedimentation

Jessica M Bryant^1,2,

Mirella L Meyer-Ficca³,

Vanessa M Dang¹,

Shelley L Berger^1,4,5,

Ralph G Meyer³

¹Department of Cell and Developmental Biology, University of Pennsylvania,

²Biomedical Graduate Studies, University of Pennsylvania,

³Department of Animal Biology and Center for Animal Transgenesis and Germ Cell Research, University of Pennsylvania,

⁴Department of Genetics, University of Pennsylvania,

⁵Department of Biology, University of Pennsylvania

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Mirella L Meyer-Ficca

.css-o250i3{font-size:18px;font-family:Open Sans,sans-serif;line-height:21.6px;}Department of Animal Biology and Center for Animal Transgenesis and Germ Cell Research

University of Pennsylvania

Separation of Spermatogenic Cell Types Using STA-PUT Velocity Sedimentation

Department of Animal Biology and Center for Animal Transgenesis and Germ Cell Research