Shelley L Berger

The SANT domain of Ada2 is required for normal acetylation of histones by the yeast SAGA complex.

Histone modifications in transcriptional regulation.

Trans-tail histone modifications: wedge or bridge?

SALSA, a variant of yeast SAGA, contains truncated Spt7, which correlates with activated transcription.

Activating signal cointegrator 2 belongs to a novel steady-state complex that contains a subset of trithorax group proteins.

A novel human Ada2 homologue functions with Gcn5 or Brg1 to coactivate transcription.

Structural basis for histone and phosphohistone binding by the GCN5 histone acetyltransferase.

Transcriptional activation via sequential histone H2B ubiquitylation and deubiquitylation, mediated by SAGA-associated Ubp8.

Histone modifications: Now summoning sumoylation.

Temporal and spatial changes in transcription factor binding and histone modifications at the steroidogenic acute regulatory protein (stAR) locus associated with stAR transcription.

Histone modification patterns during gene activation.

H2B ubiquitylation and de-ubiquitylation in gene activation.

Good fences make good neighbors: barrier elements and genomic regulation.

H2B ubiquitin protease Ubp8 and Sgf11 constitute a discrete functional module within the Saccharomyces cerevisiae SAGA complex.

Histone H3 phosphorylation can promote TBP recruitment through distinct promoter-specific mechanisms.

Maintenance of low histone ubiquitylation by Ubp10 correlates with telomere-proximal Sir2 association and gene silencing.

Phosphorylation of histone H4 serine 1 during DNA damage requires casein kinase II in S. cerevisiae.

Sumoylation of the yeast Gcn5 protein.

Structure and dimerization of the kinase domain from yeast Snf1, a member of the Snf1/AMPK protein family.

Histone sumoylation is a negative regulator in Saccharomyces cerevisiae and shows dynamic interplay with positive-acting histone modifications.

Trimethylation of histone H3 lysine 4 by Set1 in the lytic infection of human herpes simplex virus 1.

A feed-forward repression mechanism anchors the Sin3/histone deacetylase and N-CoR/SMRT corepressors on chromatin.

Phosphorylation of histone H4 Ser1 regulates sporulation in yeast and is conserved in fly and mouse spermatogenesis.

LKB1 is recruited to the p21/WAF1 promoter by p53 to mediate transcriptional activation.

Repression of p53 activity by Smyd2-mediated methylation.

In vivo dual cross-linking for identification of indirect DNA-associated proteins by chromatin immunoprecipitation.

CTCF-dependent chromatin boundary element between the latency-associated transcript and ICP0 promoters in the herpes simplex virus type 1 genome.

Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map.

The complex language of chromatin regulation during transcription.

H2B ubiquitylation acts as a barrier to Ctk1 nucleosomal recruitment prior to removal by Ubp8 within a SAGA-related complex.

p53 is regulated by the lysine demethylase LSD1.

Histone H3 K4 demethylation during activation and attenuation of GAL1 transcription in Saccharomyces cerevisiae.

New nomenclature for chromatin-modifying enzymes.

The putative cancer stem cell marker USP22 is a subunit of the human SAGA complex required for activated transcription and cell-cycle progression.

14-3-3 interaction with histone H3 involves a dual modification pattern of phosphoacetylation.

The emerging field of dynamic lysine methylation of non-histone proteins.

The histone H2B-specific ubiquitin ligase RNF20/hBRE1 acts as a putative tumor suppressor through selective regulation of gene expression.

Hit and run: transient deubiquitylase activity in a chromatin-remodeling complex.

The histone variant H3.3 regulates gene expression during lytic infection with herpes simplex virus type 1.

Out of the jaws of death: PRMT5 steers p53.

Protein acetylation microarray reveals that NuA4 controls key metabolic target regulating gluconeogenesis.

An operational definition of epigenetics.

Genome reprogramming during sporulation.

Histone H4 lysine 16 acetylation regulates cellular lifespan.

Identification and characterization of novel sirtuin inhibitor scaffolds.

Inactivation of the Sas2 histone acetyltransferase delays senescence driven by telomere dysfunction.

G9a and Glp methylate lysine 373 in the tumor suppressor p53.

Chromatin dynamics during herpes simplex virus-1 lytic infection.

Genome-wide mapping of histone H4 serine-1 phosphorylation during sporulation in Saccharomyces cerevisiae.

Keeping p53 in check: a high-stakes balancing act.

Signaling kinase AMPK activates stress-promoted transcription via histone H2B phosphorylation.

Systematic screen reveals new functional dynamics of histones H3 and H4 during gametogenesis.

Genomic comparison of the ants Camponotus floridanus and Harpegnathos saltator.

Epigenetic drugs can stimulate metastasis through enhanced expression of the pro-metastatic Ezrin gene.

Cutting edge: persistently open chromatin at effector gene loci in resting memory CD8+ T cells independent of transcriptional status.

A genetic and molecular toolbox for analyzing histone ubiquitylation and sumoylation in yeast.

The contribution of epigenetic memory to immunologic memory.

Carnitine palmitoyltransferase 1C promotes cell survival and tumor growth under conditions of metabolic stress.

Acetylation of yeast AMPK controls intrinsic aging independently of caloric restriction.

Histone H4 lysine 20 of Saccharomyces cerevisiae is monomethylated and functions in subtelomeric silencing.

MYST protein acetyltransferase activity requires active site lysine autoacetylation.

H2B ubiquitylation is part of chromatin architecture that marks exon-intron structure in budding yeast.

Transgenerational inheritance of longevity: epigenetic mysteries abound.

IDH mutation impairs histone demethylation and results in a block to cell differentiation.

Gcn5p-dependent acetylation induces degradation of the meiotic transcriptional repressor Ume6p.

The linker histone plays a dual role during gametogenesis in Saccharomyces cerevisiae.

Genome-wide and caste-specific DNA methylomes of the ants Camponotus floridanus and Harpegnathos saltator.

Phylogenetic and transcriptomic analysis of chemosensory receptors in a pair of divergent ant species reveals sex-specific signatures of odor coding.

Low-hanging fruit: targeting Brdt in the testes.

A chromatin link to caste identity in the carpenter ant Camponotus floridanus.

Social insect genomes exhibit dramatic evolution in gene composition and regulation while preserving regulatory features linked to sociality.

Genome-wide epigenetics.

Lysosome-mediated processing of chromatin in senescence.

Lamin B1 depletion in senescent cells triggers large-scale changes in gene expression and the chromatin landscape.