Edmund J. Keliher

Edmund J. Keliher

Center for Systems Biology, Massachusetts General Hospital

Affiliated withMassachusetts General Hospital

Research Area

Chemistry

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2013

Other Publications

Article	Year
Activation parameters for three reactions interconverting isomeric 4- and 6-deuteriobicyclo[3.1.0]hex-2-enes. Journal of the American Chemical Society\| PubMed ID: 11792200	2002
Perturbations by phenyl on the 1,5-hydrogen shift in 1,3(Z)-pentadiene. Another chameleonic transition region? Journal of the American Chemical Society\| PubMed ID: 15506787	2004
Efficient syntheses of four stable-isotope labeled (1R)-menthyl (1S,2S)-(+)-2-phenylcyclopropanecarboxylates. Organic & biomolecular chemistry\| PubMed ID: 16826303	2006
Effect of deuterium on the kinetics of 1,5-hydrogen shifts: 5-dideuteriomethylene-2,4,6,7,9-pentamethyl-11,11a- dihydro-12H-naphthacene. Journal of the American Chemical Society\| PubMed ID: 17288416	2007
An effect of bulk on the ratio of fragmentation to stereomutation in three cyclobutane dimers of 3-methylenecholest-4-ene. Journal of the American Chemical Society\| PubMed ID: 17941633	2007
18F labeled nanoparticles for in vivo PET-CT imaging. Bioconjugate chemistry\| PubMed ID: 19138113	2009
High-Yielding, Two-Step (18)F Labeling Strategy for (18)F-PARP1 Inhibitors. ChemMedChem\| PubMed ID: 21207434	2011
Synthesis and in vivo imaging of a 18F-labeled PARP1 inhibitor using a chemically orthogonal scavenger-assisted high-performance method. Angewandte Chemie (International ed. in English)\| PubMed ID: 21328671	2011
High-yielding, two-step 18F labeling strategy for 18F-PARP1 inhibitors. ChemMedChem\| PubMed ID: 21360818	2011
In vivo PET imaging of histone deacetylases by 18F-suberoylanilide hydroxamic acid (18F-SAHA). Journal of medicinal chemistry\| PubMed ID: 21721525	2011
89Zr-labeled dextran nanoparticles allow in vivo macrophage imaging. Bioconjugate chemistry\| PubMed ID: 22035047	2011
Reactive polymer enables efficient in vivo bioorthogonal chemistry. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 22411831	2012
Synthesis of [18F]BODIPY: bifunctional reporter for hybrid optical/positron emission tomography imaging. Angewandte Chemie (International ed. in English)\| PubMed ID: 22473535	2012
Imaging therapeutic PARP inhibition in vivo through bioorthogonally developed companion imaging agents. Neoplasia (New York, N.Y.)\| PubMed ID: 22496617	2012
Polymeric nanoparticle PET/MR imaging allows macrophage detection in atherosclerotic plaques. Circulation research\| PubMed ID: 23300273	2013
Monocyte-directed RNAi targeting CCR2 improves infarct healing in atherosclerosis-prone mice. Circulation\| PubMed ID: 23616627	2013
Targeting cathepsin E in pancreatic cancer by a small molecule allows in vivo detection. Neoplasia (New York, N.Y.)\| PubMed ID: 23814481	2013
Efficient (18)F-Labeling of Synthetic Exendin-4 Analogues for Imaging Beta Cells. ChemistryOpen\| PubMed ID: 23997998	2012