Edmund J. Keliher

Activation parameters for three reactions interconverting isomeric 4- and 6-deuteriobicyclo[3.1.0]hex-2-enes.

Perturbations by phenyl on the 1,5-hydrogen shift in 1,3(Z)-pentadiene. Another chameleonic transition region?

Efficient syntheses of four stable-isotope labeled (1R)-menthyl (1S,2S)-(+)-2-phenylcyclopropanecarboxylates.

Effect of deuterium on the kinetics of 1,5-hydrogen shifts: 5-dideuteriomethylene-2,4,6,7,9-pentamethyl-11,11a- dihydro-12H-naphthacene.

An effect of bulk on the ratio of fragmentation to stereomutation in three cyclobutane dimers of 3-methylenecholest-4-ene.

18F labeled nanoparticles for in vivo PET-CT imaging.

High-Yielding, Two-Step (18)F Labeling Strategy for (18)F-PARP1 Inhibitors.

Synthesis and in vivo imaging of a 18F-labeled PARP1 inhibitor using a chemically orthogonal scavenger-assisted high-performance method.

High-yielding, two-step 18F labeling strategy for 18F-PARP1 inhibitors.

In vivo PET imaging of histone deacetylases by 18F-suberoylanilide hydroxamic acid (18F-SAHA).

89Zr-labeled dextran nanoparticles allow in vivo macrophage imaging.

Reactive polymer enables efficient in vivo bioorthogonal chemistry.

Synthesis of [18F]BODIPY: bifunctional reporter for hybrid optical/positron emission tomography imaging.

Imaging therapeutic PARP inhibition in vivo through bioorthogonally developed companion imaging agents.

Polymeric nanoparticle PET/MR imaging allows macrophage detection in atherosclerotic plaques.

Monocyte-directed RNAi targeting CCR2 improves infarct healing in atherosclerosis-prone mice.

Targeting cathepsin E in pancreatic cancer by a small molecule allows in vivo detection.

Efficient (18)F-Labeling of Synthetic Exendin-4 Analogues for Imaging Beta Cells.