Amir Manbachi

Harvard-MIT Division of Health Sciences and Technology,
Massachusetts Institute of Technology; Center for Biomedical Engineering,
Department of Medicine,
Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology; Center for Biomedical Engineering, Department of Medicine

Brigham and Women's Hospital

BIOGRAPHY

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PUBLICATIONS

Microcirculation within grooved substrates regulates cell positioning and cell docking inside microfluidic channels.

Lab on a chip May, 2008 | Pubmed ID: 18432345

High-throughput screening of cell responses to biomaterials.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences Oct, 2008 | Pubmed ID: 18586092

A computational and experimental study inside microfluidic systems: the role of shear stress and flow recirculation in cell docking.

Biomedical microdevices Aug, 2010 | Pubmed ID: 20300857

On the shape of the common carotid artery with implications for blood velocity profiles.

Physiological measurement Dec, 2011 | Pubmed ID: 22031538

Surface acoustic waves induced micropatterning of cells in gelatin methacryloyl (GelMA) hydrogels.

Biofabrication Feb, 2017 | Pubmed ID: 28195834

Starting a Medical Technology Venture as a Young Academic Innovator or Student Entrepreneur.

Annals of biomedical engineering Jan, 2018 | Pubmed ID: 29019076

Virtual fluoroscopy for intraoperative C-arm positioning and radiation dose reduction.

Journal of medical imaging (Bellingham, Wash.) , | Pubmed ID: 29487882

Design and validation of an open-source library of dynamic reference frames for research and education in optical tracking.

Journal of medical imaging (Bellingham, Wash.) , | Pubmed ID: 29487887

Microfluidics-Enabled Multimaterial Maskless Stereolithographic Bioprinting.

Advanced materials (Deerfield Beach, Fla.) Jul, 2018 | Pubmed ID: 29737048

Clinical Translation of the LevelCheck Decision Support Algorithm for Target Localization in Spine Surgery.

Annals of biomedical engineering , | Pubmed ID: 30051244

Transcranioplasty Ultrasound Through a Sonolucent Cranial Implant Made of Polymethyl Methacrylate: Phantom Study Comparing Ultrasound, Computed Tomography, and Magnetic Resonance Imaging.

The Journal of craniofacial surgery Oct, 2019 | Pubmed ID: 31188246

Sonolucent Cranial Implants: Cadaveric Study and Clinical Findings Supporting Diagnostic and Therapeutic Transcranioplasty Ultrasound.

The Journal of craniofacial surgery Jul, 2019 | Pubmed ID: 31299743

The effect of renin-angiotensin system blockers on spinal cord dysfunction and imaging features of spinal cord compression in patients with symptomatic cervical spondylosis.

The spine journal : official journal of the North American Spine Society , | Pubmed ID: 31821888

Curricular Advancement of Biomedical Engineering Undergraduate Design Projects Beyond 1 Year: A Pilot Study.

Annals of biomedical engineering , | Pubmed ID: 31828455

Correction to: Curricular Advancement of Biomedical Engineering Undergraduate Design Projects Beyond 1 Year: A Pilot Study.

Annals of biomedical engineering , | Pubmed ID: 31863229

Three-dimensional assessment of robot-assisted pedicle screw placement accuracy and instrumentation reliability based on a preplanned trajectory.

Journal of neurosurgery. Spine , | Pubmed ID: 32470927

Epidural Oscillating Cardiac-Gated Intracranial Implant Modulates Cerebral Blood Flow.

Neurosurgery , | Pubmed ID: 32533835

Minimally invasive therapeutic ultrasound: Ultrasound-guided ultrasound ablation in neuro-oncology.

Ultrasonics , | Pubmed ID: 32619834

Ultrasound in Traumatic Spinal Cord Injury: A Wide-Open Field.

Neurosurgery , | Pubmed ID: 34098572

Social Non-profit Bioentrepreneurship: Current Status and Future Impact on Global Health.

Frontiers in public health , | Pubmed ID: 34660499

In Reply: Ultrasound in Traumatic Spinal Cord Injury: A Wide-Open Field.

Neurosurgery , | Pubmed ID: 34995249

A MINIATURE LASER SPECKLE CONTRAST IMAGER FOR MONITORING OF THE NEURO-MODULATORY EFFECT OF TRANSCRANIAL FOCUSED ULTRASOUND STIMULATION.

Proceedings of the 2021 Design of Medical Devices Conference (DMD2021) : April 12-15, 2021 virtual, online. ASME Design of Medical Devices Conference (2021 : Online) , | Pubmed ID: 35224565

Automatic detection of cotton balls during brain surgery: Where deep learning meets ultrasound imaging to tackle foreign objects.

Proceedings of SPIE--the International Society for Optical Engineering Feb, 2021 | Pubmed ID: 35233128

THE DESIGN AND USE OF A MINIMALLY-INVASIVE, EXPANDABLE RETRACTOR FOR DEEP-SEATED BRAIN LESIONS.

Proceedings of the 2021 Design of Medical Devices Conference (DMD2021) : April 12-15, 2021 virtual, online. ASME Design of Medical Devices Conference (2021 : Online) , | Pubmed ID: 35233564

DESIGN OF AN ULTRASOUND PROBE HOLDER TO MINIMIZE MOTION ARTIFACT DURING SONOGRAPHY.

Proceedings of the 2021 Design of Medical Devices Conference (DMD2021) : April 12-15, 2021 virtual, online. ASME Design of Medical Devices Conference (2021 : Online) , | Pubmed ID: 35237770

DESIGN AND FABRICATION OF A FOCUSED ULTRASOUND DEVICE FOR MINIMALLY-INVASIVE NEUROSURGERY: REPORTING A SECOND, MINIATURIZED AND MR-COMPATIBLE PROTOTYPE WITH STEERING CAPABILITIES.

Proceedings of the 2021 Design of Medical Devices Conference (DMD2021) : April 12-15, 2021 virtual, online. ASME Design of Medical Devices Conference (2021 : Online) , | Pubmed ID: 35237771

USDL: Inexpensive Medical Imaging Using Deep Learning Techniques and Ultrasound Technology.

2020 Design of Medical Devices Conference (DMD 2020). Design of Medical Devices Conferences (2020 : Minneapolis, Minn.) , | Pubmed ID: 35253013

DEVELOPMENT OF A PORTABLE BLOOD POTASSIUM MONITORING DEVICE FOR DIALYSIS PATIENTS.

2020 Design of Medical Devices Conference (DMD 2020). Design of Medical Devices Conferences (2020 : Minneapolis, Minn.) , | Pubmed ID: 35253014

DEVELOPMENT OF VOICE-CONTROLLED SMART SURGICAL BED.

2020 Design of Medical Devices Conference (DMD 2020). Design of Medical Devices Conferences (2020 : Minneapolis, Minn.) , | Pubmed ID: 35253015

Minimizing cotton ball retention in neurological procedures.

2020 Design of Medical Devices Conference (DMD 2020). Design of Medical Devices Conferences (2020 : Minneapolis, Minn.) , | Pubmed ID: 35253016

Development of a Smart Hospital Assistant: Integrating Artificial Intelligence and a Voice-User Interface for Improved Surgical Outcomes.

Proceedings of SPIE--the International Society for Optical Engineering , | Pubmed ID: 35341075

Minimizing cotton retention in neurosurgical procedures: which imaging modality can help?

Proceedings of SPIE--the International Society for Optical Engineering , | Pubmed ID: 35350430

Advances in monitoring for acute spinal cord injury: a narrative review of current literature.

The spine journal : official journal of the North American Spine Society Mar, 2022 | Pubmed ID: 35351667

Ultrasound monitoring of microcirculation: An original study from the laboratory bench to the clinic.

Microcirculation (New York, N.Y. : 1994) , | Pubmed ID: 35611457

Applications of elastography in operative neurosurgery: A systematic review.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia , | Pubmed ID: 35933785

Porcine Model of Spinal Cord Injury: A Systematic Review.

Neurotrauma reports , 2022 | Pubmed ID: 36204385

Applications of Focused Ultrasound for the Treatment of Glioblastoma: A New Frontier.

Cancers Oct, 2022 | Pubmed ID: 36230843

Automatic detection of foreign body objects in neurosurgery using a deep learning approach on intraoperative ultrasound images: From animal models to first in-human testing.

Frontiers in surgery , 2022 | Pubmed ID: 36532130

Towards standardization of the parameters for opening the blood-brain barrier with focused ultrasound to treat glioblastoma multiforme: A systematic review of the devices, animal models, and therapeutic compounds used in rodent tumor models.

Frontiers in oncology , 2022 | Pubmed ID: 36873300

FlowMorph: Morphological Segmentation of Ultrasound-Monitored Spinal Cord Microcirculation.

IEEE Biomedical Circuits and Systems Conference : healthcare technology : [proceedings]. IEEE Biomedical Circuits and Systems Conference Oct, 2022 | Pubmed ID: 36695674

Visualizing tactile feedback: an overview of current technologies with a focus on ultrasound elastography.

Frontiers in medical technology , 2023 | Pubmed ID: 37854637

Early versus late surgical decompression for patients with acute traumatic central cord syndrome: a systematic review and meta-analysis.

The spine journal : official journal of the North American Spine Society Mar, 2024 | Pubmed ID: 37890727

Tethered spinal cord tension assessed via ultrasound elastography in computational and intraoperative human studies.

Communications medicine Jan, 2024 | Pubmed ID: 38182729

Non-contrast ultrasound image analysis for spatial and temporal distribution of blood flow after spinal cord injury.

Scientific reports Jan, 2024 | Pubmed ID: 38184676

INSTITUTIONS

Brigham and Women's Hospital

Johns Hopkins University School of Medicine

Johns Hopkins University

JOVE ARTICLES

A Microfluidic Device with Groove Patterns for Studying Cellular Behavior

Bong Geun Chung¹,

Amir Manbachi¹,

Ali Khademhosseini¹

¹Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology; Center for Biomedical Engineering, Department of Medicine, Brigham and Women's Hospital

Biology

A Gradient-generating Microfluidic Device for Cell Biology

Bong Geun Chung¹,

Amir Manbachi¹,

Wajeeh Saadi¹,

Francis Lin¹,

Noo Li Jeon¹,

Ali Khademhosseini¹

¹Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology; Center for Biomedical Engineering, Department of Medicine, Brigham and Women's Hospital

Biology

Disruption of the Blood-Spinal Cord Barrier Using Low-Intensity Focused Ultrasound in a Rat Model

Meghana Bhimreddy¹,

Denis Routkevitch^1,2,3,

Andrew M. Hersh¹,

Ali Mohammadabadi^1,3,

Arjun K. Menta¹,

Kelly Jiang¹,

Carly Weber-Levine¹,

A. Daniel Davidar¹,

Joshua Punnoose^1,2,3,

Kelley M. Kempski Leadingham^1,3,

Joshua C. Doloff²,

Betty Tyler¹,

Nicholas Theodore^1,3,

Amir Manbachi^1,2,3,4,5,6

¹Department of Neurosurgery, Johns Hopkins University School of Medicine,

²Department of Biomedical Engineering, Johns Hopkins University,

³HEPIUS Innovation Laboratory, Johns Hopkins University School of Medicine,

⁴Department of Electrical Engineering and Computer Science, Johns Hopkins University,

⁵Department of Mechanical Engineering, Johns Hopkins University,

⁶Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University

Bioengineering

Focused Ultrasound Neuromodulation of Human In Vitro Neural Cultures in Multi-Well Microelectrode Arrays

Ruixing Liang^1,2,

Griffin Mess^2,3,

Joshua Punnoose^2,3,

Kelley M. Kempski Leadingham^2,3,

Constantin Smit^2,3,

Nitish Thakor^1,4,

Christa W. Habela³,

Betty Tyler³,

Yousef Salimpour³,

Amir Manbachi^1,2,3,4,5,6

¹Electrical and Computer Engineering, Johns Hopkins University,

²HEPIUS Innovation Laboratory, Johns Hopkins University School of Medicine,

³Neurosurgery, Johns Hopkins University School of Medicine,

⁴Biomedical Engineering, Johns Hopkins University School of Medicine,

⁵Mechanical Engineering, Johns Hopkins University,

⁶Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine

Focused Ultrasound Neuromodulation of Human <em>In Vitro</em> Neural Cultures in Multi-Well Microelectrode Arrays

Sonodynamic Therapy for the Treatment of Glioblastoma Multiforme in a Mouse Model Using a Portable Benchtop Focused Ultrasound System

Griffin Mess^1,2,

Taylor Anderson^1,2,

Shivani Kapoor³,

Rasika Thombre^1,2,

Ruixing Liang⁴,

Emre Derin¹,

Kelley M. Kempski-Leadingham¹,

Santosh K. Yadav⁵,

Betty Tyler¹,

Amir Manbachi^1,2,4,6,7

¹Department of Neurosurgery, Johns Hopkins University School of Medicine,

²Department of Biomedical Engineering, Johns Hopkins University,

³Krieger School of Arts and Sciences, Johns Hopkins University,

⁴Department of Electrical Engineering and Computer Science, Johns Hopkins University,

⁵Department of Radiology, Cancer Imaging Division, Johns Hopkins University School of Medicine,

⁶Department of Mechanical Engineering, Johns Hopkins University,

⁷Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine

Bioengineering

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