Darrell N. Kotton

Stem cell antigen-1 expression in the pulmonary vascular endothelium.

Side population cells and Bcrp1 expression in lung.

Translational physiology: origin and phenotype of lung side population cells.

Lung stem cells: new paradigms.

Embryonic lung side population cells are hematopoietic and vascular precursors.

A novel stem-cell population in adult liver with potent hematopoietic-reconstitution activity.

Efficiency of transduction of highly purified murine hematopoietic stem cells by lentiviral and oncoretroviral vectors under conditions of minimal in vitro manipulation.

Failure of bone marrow to reconstitute lung epithelium.

Exogenous control of mammalian gene expression via modulation of translational termination.

Lung stem cells.

Dual-promoter lentiviral system allows inducible expression of noxious proteins in macrophages.

The prolonged life-span of alveolar macrophages.

Another notch in stem cell biology: Drosophila intestinal stem cells and the specification of cell fates.

Sustained expression of alpha1-antitrypsin after transplantation of manipulated hematopoietic stem cells.

Induced pluripotent stem cell generation using a single lentiviral stem cell cassette.

Transcriptional analysis of fracture healing and the induction of embryonic stem cell-related genes.

Pulmonary alveolar proteinosis: a bench-to-bedside story of granulocyte-macrophage colony-stimulating factor dysfunction.

Excision of reprogramming transgenes improves the differentiation potential of iPS cells generated with a single excisable vector.

Amelioration of emphysema in mice through lentiviral transduction of long-lived pulmonary alveolar macrophages.

The role of skin-derived dendritic cells in CD8+ T cell priming following immunization with lentivectors.

Generation of transgene-free lung disease-specific human induced pluripotent stem cells using a single excisable lentiviral stem cell cassette.

FOXO1 modulates osteoblast differentiation.

Mouse ES and iPS cells can form similar definitive endoderm despite differences in imprinted genes.

Cell plasticity in lung injury and repair: report from an NHLBI workshop, April 19-20, 2010.

A shift from cell cultures to creatures: in vivo imaging of small animals in experimental regenerative medicine.

Programmatic change: lung disease research in the era of induced pluripotency.

Biophysical properties of slow potassium channels in human embryonic stem cell derived cardiomyocytes implicate subunit stoichiometry.

Role of Nanog in the maintenance of marrow stromal stem cells during post natal bone regeneration.

Are embryonic stem and induced pluripotent stem cells the same or different? Implications for their potential therapeutic use.

Case records of the Massachusetts General Hospital. Case 2-2012. A 63-year-old woman with dyspnea and rapidly progressive respiratory failure.

Maintenance and repair of the lung endothelium does not involve contributions from marrow-derived endothelial precursor cells.

Self-renewing endodermal progenitor lines generated from human pluripotent stem cells.

Efficient derivation of purified lung and thyroid progenitors from embryonic stem cells.

Next-generation regeneration: the hope and hype of lung stem cell research.

Modeling supravalvular aortic stenosis syndrome with human induced pluripotent stem cells.

The Transcription Factors Grainyhead-like 2 and NK2-Homeobox 1 Form a Regulatory Loop That Coordinates Lung Epithelial Cell Morphogenesis and Differentiation.

The 2012 Nobel Prize in physiology or medicine: democratizing pluripotency for lung researchers.

Induced pluripotent stem cells used to reveal drug actions in a long QT syndrome family with complex genetics.

Lentiviral delivery of RNAi for in vivo lineage-specific modulation of gene expression in mouse lung macrophages.

The aryl hydrocarbon receptor directs hematopoietic progenitor cell expansion and differentiation.

KDR identifies a conserved human and murine hepatic progenitor and instructs early liver development.

Lung regeneration: mechanisms, applications and emerging stem cell populations.

Derivation of Endodermal Progenitors From Pluripotent Stem Cells.

Targeted correction and restored function of the CFTR gene in cystic fibrosis induced pluripotent stem cells.

Embryonic and induced pluripotent stem cells for lung regeneration.

Emergence of a stage-dependent human liver disease signature with directed differentiation of alpha-1 antitrypsin-deficient iPS cells.

Regeneration of Thyroid Function by Transplantation of Differentiated Pluripotent Stem Cells.

Mouse ESC Differentiation to Nkx2.1+ Lung and Thyroid Progenitors.

Regenerative therapy for hypothyroidism: Mechanisms and possibilities.

Efficient Derivation of Functional Human Airway Epithelium from Pluripotent Stem Cells via Temporal Regulation of Wnt Signaling.

Prospective isolation of NKX2-1-expressing human lung progenitors derived from pluripotent stem cells.

Vascular smooth muscle cells derived from inbred swine induced pluripotent stem cells for vascular tissue engineering.

Pluripotent stem cell differentiation reveals distinct developmental pathways regulating lung- versus thyroid-lineage specification.

Differentiation of Human Pluripotent Stem Cells into Functional Lung Alveolar Epithelial Cells.

Claudin-18: unexpected regulator of lung alveolar epithelial cell proliferation.

Single-Cell Transcriptomic Profiling of Pluripotent Stem Cell-Derived SCGB3A2+ Airway Epithelium.

Circulating Truncated Alpha-1 Antitrypsin Glycoprotein in Patient Plasma Retains Anti-Inflammatory Capacity.

Generation of a Purified iPSC-Derived Smooth Muscle-like Population for Cell Sheet Engineering.

Derivation of self-renewing lung alveolar epithelial type II cells from human pluripotent stem cells.

Reconstructed Single-Cell Fate Trajectories Define Lineage Plasticity Windows during Differentiation of Human PSC-Derived Distal Lung Progenitors.

The in vivo genetic program of murine primordial lung epithelial progenitors.

Organoids Model Transcriptional Hallmarks of Oncogenic KRAS Activation in Lung Epithelial Progenitor Cells.

SARS-CoV-2 Infection of Pluripotent Stem Cell-Derived Human Lung Alveolar Type 2 Cells Elicits a Rapid Epithelial-Intrinsic Inflammatory Response.

Epithelial Stem and Progenitor Cells in Lung Repair and Regeneration.

Derivation of Airway Basal Stem Cells from Human Pluripotent Stem Cells.

Actionable Cytopathogenic Host Responses of Human Alveolar Type 2 Cells to SARS-CoV-2.

Derivation of Thyroid Follicular Cells From Pluripotent Stem Cells: Insights From Development and Implications for Regenerative Medicine.

Differentiation of human pluripotent stem cells into functional airway basal stem cells.

Morphological cell profiling of SARS-CoV-2 infection identifies drug repurposing candidates for COVID-19.

Patient-specific iPSCs carrying an SFTPC mutation reveal the intrinsic alveolar epithelial dysfunction at the inception of interstitial lung disease.

Editorial: Progenitors and Stem Cells in Thyroid Development, Disease, and Regeneration.

Human distal airways contain a multipotent secretory cell that can regenerate alveoli.