Hazel Sive

Cement gland-specific activation of the Xag1 promoter is regulated by co-operation of putative Ets and ATF/CREB transcription factors.

What's your position? the Xenopus cement gland as a paradigm of regional specification.

vhnf1 and Fgf signals synergize to specify rhombomere identity in the zebrafish hindbrain.

Early requirement for fgf8 function during hindbrain pattern formation in zebrafish.

nlz gene family is required for hindbrain patterning in the zebrafish.

The Meis3 protein and retinoid signaling interact to pattern the Xenopus hindbrain.

Strategies of vertebrate neurulation and a re-evaluation of teleost neural tube formation.

Identification and characterisation of the posteriorly-expressed Xenopus neurotrophin receptor homolog genes fullback and fullback-like.

Specification of the enveloping layer and lack of autoneuralization in zebrafish embryonic explants.

Combined haploid and insertional mutation screen in the zebrafish.

Initial formation of zebrafish brain ventricles occurs independently of circulation and requires the nagie oko and snakehead/atp1a1a.1 gene products.

Identification of a BMP inhibitor-responsive promoter module required for expression of the early neural gene zic1.

Development of the primary mouth in Xenopus laevis.

Zebrafish promoter microarrays identify actively transcribed embryonic genes.

The zic1 gene is an activator of Wnt signaling.

Disease connections: a new peer-reviewed dialog.

Whitesnake/sfpq is required for cell survival and neuronal development in the zebrafish.

Investigator profile. An interview with Hazel Sive, Ph.D. Interview by Vicki Glaser.

Formation of the zebrafish midbrain-hindbrain boundary constriction requires laminin-dependent basal constriction.

Characterization and classification of zebrafish brain morphology mutants.

The Wnt antagonists Frzb-1 and Crescent locally regulate basement membrane dissolution in the developing primary mouth.

Coherent but overlapping expression of microRNAs and their targets during vertebrate development.

Totally tubular: the mystery behind function and origin of the brain ventricular system.

Understanding the role of DISC1 in psychiatric disease and during normal development.

Epithelial relaxation mediated by the myosin phosphatase regulator Mypt1 is required for brain ventricle lumen expansion and hindbrain morphogenesis.

Microinjection of Xenopus embryos.

Isolation of Xenopus oocytes.

Defolliculation of Xenopus oocytes.

Microinjection of Xenopus oocytes.

Calibration of the injection volume for microinjection of Xenopus oocytes and embryos.

Microinjection of RNA and preparation of secreted proteins from Xenopus oocytes.

Dejellying Xenopus laevis Embryos.

Removing the Vitelline Membrane from Xenopus laevis Embryos.

Handling Xenopus laevis Adults.

Inducing Ovulation in Xenopus laevis.

Isolating Xenopus laevis Testes.

Xenopus laevis Egg Collection.

Xenopus laevis In Vitro Fertilization and Natural Mating Methods.

Embryo dissection and micromanipulation tools.

Housing and Feeding of Xenopus laevis.

Animal Cap Isolation from Xenopus laevis.

Dissociation and Reaggregation of Xenopus laevis Animal Caps.

Ectodermal (Animal Cap) Layer Separations in Xenopus laevis.

Xenopus laevis Animal Cap/Vegetal Endoderm Conjugates.

Xenopus laevis Animal Cap/Dorsal Mesoderm Conjugates.

Xenopus laevis Keller Explants.

Xenopus laevis Einstecks.

Transplantation of Xenopus laevis Lens Ectoderm.

Dissection of Tightly Adhering Xenopus laevis Tissues by Trypsin Treatment.

Cortical Isolation from Xenopus laevis Oocytes and Eggs.

Microdissection: Explant and Transplant Assays in Xenopus laevis.

Baskets for in situ hybridization and immunohistochemistry.

Synthesis and purification of digoxigenin-labeled RNA probes for in situ hybridization.

'Model' or 'tool'? New definitions for translational research.

Keeping two animal systems in one lab - a frog plus fish case study.

Disc1 regulates both β-catenin-mediated and noncanonical Wnt signaling during vertebrate embryogenesis.

Common DISC1 polymorphisms disrupt Wnt/GSK3β signaling and brain development.

Isolation of DNA from red blood cells in Xenopus.

Conserved function of lincRNAs in vertebrate embryonic development despite rapid sequence evolution.

Zebrafish homologs of genes within 16p11.2, a genomic region associated with brain disorders, are active during brain development, and include two deletion dosage sensor genes.

Multiple roles for the Na,K-ATPase subunits, Atp1a1 and Fxyd1, during brain ventricle development.

Extensive alternative polyadenylation during zebrafish development.

Efficient shRNA-Mediated Inhibition of Gene Expression in Zebrafish.

Education: online on-ramps.

Poly(A)-tail profiling reveals an embryonic switch in translational control.