Jamie W. Joseph

A pyruvate cycling pathway involving cytosolic NADP-dependent isocitrate dehydrogenase regulates glucose-stimulated insulin secretion.

The mitochondrial citrate/isocitrate carrier plays a regulatory role in glucose-stimulated insulin secretion.

Normal flux through ATP-citrate lyase or fatty acid synthase is not required for glucose-stimulated insulin secretion.

Galphaz negatively regulates insulin secretion and glucose clearance.

Chronic suppression of acetyl-CoA carboxylase 1 in beta-cells impairs insulin secretion via inhibition of glucose rather than lipid metabolism.

Metabolic cycling in control of glucose-stimulated insulin secretion.

The mitochondrial 2-oxoglutarate carrier is part of a metabolic pathway that mediates glucose- and glutamine-stimulated insulin secretion.

Thermodynamic investigation of the binding of dissymmetric pyrenyl-gemini surfactants to DNA.

Aryl hydrocarbon receptor nuclear translocator/hypoxia-inducible factor-1{beta} plays a critical role in maintaining glucose-stimulated anaplerosis and insulin release from pancreatic {beta}-cells.

Overcoming the spatial barriers of the stimulus secretion cascade in pancreatic β-cells.

Metabolomic analysis of pancreatic β-cell insulin release in response to glucose.

Mitochondrial glutathione transport is a key determinant of neuronal susceptibility to oxidative and nitrosative stress.

Functional plasticity of the human infant β-cell exocytotic phenotype.

Assessment of the metabolic pathways associated with glucose-stimulated biphasic insulin secretion.

Mitochondrial metabolism of pyruvate is essential for regulating glucose-stimulated insulin secretion.