Jonathon Howard

A brief scientific biography of Prof. Alan J. Hunt.

Motor regulation results in distal forces that bend partially disintegrated Chlamydomonas axonemes into circular arcs.

Stu2, the budding yeast XMAP215/Dis1 homolog, promotes assembly of yeast microtubules by increasing growth rate and decreasing catastrophe frequency.

Quantitative cell biology: the essential role of theory.

The microtubule-based cytoskeleton is a component of a mechanical signaling pathway in fly campaniform receptors.

The motility of axonemal dynein is regulated by the tubulin code.

Kinesin Kip2 enhances microtubule growth in vitro through length-dependent feedback on polymerization and catastrophe.

Regulation of Microtubule Growth and Catastrophe: Unifying Theory and Experiment.

Splicing of Nascent RNA Coincides with Intron Exit from RNA Polymerase II.

Independent Control of the Static and Dynamic Components of the Chlamydomonas Flagellar Beat.

Microtubules: 50 years on from the discovery of tubulin.

Automatic optimal filament segmentation with sub-pixel accuracy using generalized linear models and B-spline level-sets.

Broken detailed balance at mesoscopic scales in active biological systems.

Dynamic curvature regulation accounts for the symmetric and asymmetric beats of Chlamydomonas flagella.

A force-generating machinery maintains the spindle at the cell center during mitosis.

The Mitotic Spindle in the One-Cell C. elegans Embryo Is Positioned with High Precision and Stability.

Mechanism of microtubule lumen entry for the α-tubulin acetyltransferase enzyme αTAT1.

Curvature regulation of the ciliary beat through axonemal twist.

Structural Biology: A Force-Sensitive Ion Channel Springs to Life.

Physical Limits on the Precision of Mitotic Spindle Positioning by Microtubule Pushing forces: Mechanics of mitotic spindle positioning.

Structural Biology: Piezo Senses Tension through Curvature.

Label-free high-speed wide-field imaging of single microtubules using interference reflection microscopy.

Heat Oscillations Driven by the Embryonic Cell Cycle Reveal the Energetic Costs of Signaling.

Spastin is a dual-function enzyme that severs microtubules and promotes their regrowth to increase the number and mass of microtubules.

The dynamic and structural properties of axonemal tubulins support the high length stability of cilia.

Force Generated by Two Kinesin Motors Depends on the Load Direction and Intermolecular Coupling.

Nicotinamide adenine dinucleotides and their precursor NMN have no direct effect on microtubule dynamics in purified brain tubulin.

The Kinetics of Nucleotide Binding to Isolated Chlamydomonas Axonemes Using UV-TIRF Microscopy.

Predicted Effects of Severing Enzymes on the Length Distribution and Total Mass of Microtubules.

Three Beads Are Better Than One.

Contribution of increasing plasma membrane to the energetic cost of early zebrafish embryogenesis.

Purification of Ciliary Tubulin from Chlamydomonas reinhardtii.

Cutting, Amplifying, and Aligning Microtubules with Severing Enzymes.

Physical bioenergetics: Energy fluxes, budgets, and constraints in cells.

Focal laser stimulation of fly nociceptors activates distinct axonal and dendritic Ca signals.

The narrowing of dendrite branches across nodes follows a well-defined scaling law.

Structures of outer-arm dynein array on microtubule doublet reveal a motor coordination mechanism.

Counting fluorescently labeled proteins in tissues in the spinning disk microscope using single-molecule calibrations.

In Vitro Reconstitution of Microtubule Dynamics and Severing Imaged by Label-Free Interference-Reflection Microscopy.