Xi Chen

The histone methyltransferase Smyd2 is a negative regulator of macrophage activation by suppressing interleukin 6 (IL-6) and tumor necrosis factor α (TNF-α) production.

Broad H3K4me3 is associated with increased transcription elongation and enhancer activity at tumor-suppressor genes.

EglN2 associates with the NRF1-PGC1α complex and controls mitochondrial function in breast cancer.

Endogenous dendritic cells from the tumor microenvironment support T-ALL growth via IGF1R activation.

Outcomes of cataract surgery with residents as primary surgeons in the Veterans Affairs Healthcare System.

Colorectal Cancer Cell Line Proteomes Are Representative of Primary Tumors and Predict Drug Sensitivity.

SCP4 Promotes Gluconeogenesis Through FoxO1/3a Dephosphorylation.

Genome-wide identification and differential analysis of translational initiation.

Pharmacological targeting of MYC-regulated IRE1/XBP1 pathway suppresses MYC-driven breast cancer.

Rapid inhibition of atherosclerotic plaque progression by sonodynamic therapy.

miR-30a Remodels Subcutaneous Adipose Tissue Inflammation to Improve Insulin Sensitivity in Obesity.

Functional Annotation of ESR1 Gene Fusions in Estrogen Receptor-Positive Breast Cancer.

miR-205 Regulates Basal Cell Identity and Stem Cell Regenerative Potential During Mammary Reconstitution.

Quantitative Real-Time Imaging of Glutathione with Subcellular Resolution.

Is a Tumor Suppressor Gene in Colorectal Cancer.

Adaptive endoplasmic reticulum stress signalling via IRE1α-XBP1 preserves self-renewal of haematopoietic and pre-leukaemic stem cells.

The IRE1 endoplasmic reticulum stress sensor activates natural killer cell immunity in part by regulating c-Myc.

PTPN3 acts as a tumor suppressor and boosts TGF-β signaling independent of its phosphatase activity.

Comprehensive characterization of circular RNAs in ~ 1000 human cancer cell lines.

Integrated Proteogenomic Characterization of Clear Cell Renal Cell Carcinoma.

The SINEB1 element in the long non-coding RNA Malat1 is necessary for TDP-43 proteostasis.

12-h clock regulation of genetic information flow by XBP1s.

Proteogenomic Characterization of Endometrial Carcinoma.

Neurofibromin Is an Estrogen Receptor-α Transcriptional Co-repressor in Breast Cancer.

Psoriasis Vulgaris of Blood Heat Syndrome in Plasma Based on Widely Targeted Techniques.