Centre for Biomedical Research
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HIV-1 down-modulates gamma signaling chain of Fc gamma R in human macrophages: a possible mechanism for inhibition of phagocytosis.
Journal of immunology (Baltimore, Md. : 1950) Mar, 2002 | Pubmed ID: 11884460
Coreceptor phenotype of natural human immunodeficiency virus with nef deleted evolves in vivo, leading to increased virulence.
Journal of virology Jul, 2002 | Pubmed ID: 12072497
The role of monocytes and macrophages in the pathogenesis of HIV-1 infection.
Current medicinal chemistry Nov, 2002 | Pubmed ID: 12369874
Proline residues within spacer peptide p1 are important for human immunodeficiency virus type 1 infectivity, protein processing, and genomic RNA dimer stability.
Journal of virology Nov, 2002 | Pubmed ID: 12388684
Selectively reduced tat mRNA heralds the decline in productive human immunodeficiency virus type 1 infection in monocyte-derived macrophages.
Journal of virology Dec, 2002 | Pubmed ID: 12438587
Virion-associated cholesterol is critical for the maintenance of HIV-1 structure and infectivity.
AIDS (London, England) Nov, 2002 | Pubmed ID: 12441796
The influence of cytokines, chemokines and their receptors on HIV-1 replication in monocytes and macrophages.
Reviews in medical virology Jan-Feb, 2003 | Pubmed ID: 12516061
Analysis of HIV-1 viral load in seminal plasma samples.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology Feb, 2003 | Pubmed ID: 12600655
Defective phagocytosis by human monocyte/macrophages following HIV-1 infection: underlying mechanisms and modulation by adjunctive cytokine therapy.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology Feb, 2003 | Pubmed ID: 12600656
Immunological and virological failure after antiretroviral therapy is associated with enhanced peripheral and thymic pathogenicity.
The Journal of infectious diseases Jun, 2003 | Pubmed ID: 12792868
HIV and cells of macrophage/dendritic lineage and other non-T cell reservoirs: new answers yield new questions.
Journal of leukocyte biology Nov, 2003 | Pubmed ID: 12960251
Human immunodeficiency virus type 1 infection inhibits granulocyte-macrophage colony-stimulating factor-induced activation of STAT5A in human monocyte-derived macrophages.
Journal of virology Dec, 2003 | Pubmed ID: 14610185
Phagocytic efficiency of monocytes and macrophages obtained from Sydney blood bank cohort members infected with an attenuated strain of HIV-1.
Journal of acquired immune deficiency syndromes (1999) Dec, 2003 | Pubmed ID: 14657753
The molecular epidemiology of HIV-1 in South and East Asia.
Current HIV research Apr, 2003 | Pubmed ID: 15043206
Interferon-gamma therapy activates human monocytes for enhanced phagocytosis of Mycobacterium avium complex in HIV-infected individuals.
HIV clinical trials Mar-Apr, 2004 | Pubmed ID: 15116283
Longitudinal analysis of nef/long terminal repeat-deleted HIV-1 in blood and cerebrospinal fluid of a long-term survivor who developed HIV-associated dementia.
The Journal of infectious diseases Dec, 2004 | Pubmed ID: 15551218
Locking the door to HIV entry: how far can we go?
AIDS (London, England) Nov, 2004 | Pubmed ID: 15577654
Pathogenesis of macrophage tropic HIV-1.
Current HIV research Jan, 2005 | Pubmed ID: 15638723
The molecular epidemiology of HIV type 1 among Vietnamese Australian injecting drug users in Melbourne, Australia.
AIDS research and human retroviruses Dec, 2004 | Pubmed ID: 15650430
Evaluation of a low cost reverse transcriptase assay for plasma HIV-1 viral load monitoring.
Current HIV research Apr, 2005 | Pubmed ID: 15853722
In vivo replication kinetics of a nef-deleted strain of HIV-1.
AIDS (London, England) May, 2005 | Pubmed ID: 15867504
Uncoupling coreceptor usage of human immunodeficiency virus type 1 (HIV-1) from macrophage tropism reveals biological properties of CCR5-restricted HIV-1 isolates from patients with acquired immunodeficiency syndrome.
Virology Jul, 2005 | Pubmed ID: 15916792
Antiretroviral compounds: mechanisms underlying failure of HAART to eradicate HIV-1.
Current medicinal chemistry , 2005 | Pubmed ID: 16029143
Isolation of human immunodeficiency virus type 1 from peripheral blood monocytes.
Methods in molecular biology (Clifton, N.J.) , 2005 | Pubmed ID: 16061964
Phenotypic characterization of blood monocytes from HIV-infected individuals.
Methods in molecular biology (Clifton, N.J.) , 2005 | Pubmed ID: 16061988
Transendothelial migration of monocytes: the underlying molecular mechanisms and consequences of HIV-1 infection.
Current HIV research Oct, 2005 | Pubmed ID: 16250878
Phagocytosis stimulates mobilization and shedding of intracellular CD16A in human monocytes and macrophages: inhibition by HIV-1 infection.
Journal of leukocyte biology Feb, 2006 | Pubmed ID: 16301325
Comparison of two human immunodeficiency virus (HIV) RNA surrogate assays to the standard HIV RNA assay.
Journal of clinical microbiology Dec, 2005 | Pubmed ID: 16333081
Efficacy of Cyto-Chex blood preservative for delayed manual CD4 testing using Dynal T4 Quant CD4 test among HIV-infected persons in Zambia.
Journal of acquired immune deficiency syndromes (1999) Feb, 2006 | Pubmed ID: 16394848
Normal CD16 expression and phagocytosis of Mycobacterium avium complex by monocytes from a current cohort of HIV-1-infected patients.
The Journal of infectious diseases Mar, 2006 | Pubmed ID: 16453265
Adverse effects of antiretroviral drugs on HIV-1-infected and -uninfected human monocyte-derived macrophages.
Journal of acquired immune deficiency syndromes (1999) May, 2006 | Pubmed ID: 16639337
Impaired complement-mediated phagocytosis by HIV type-1-infected human monocyte-derived macrophages involves a cAMP-dependent mechanism.
AIDS research and human retroviruses Jul, 2006 | Pubmed ID: 16831086
A reliable and inexpensive EasyCD4 assay for monitoring HIV-infected individuals in resource-limited settings.
Journal of acquired immune deficiency syndromes (1999) Sep, 2006 | Pubmed ID: 16885780
Advances in macrophage and dendritic cell biology in HIV-1 infection stress key understudied areas in infection, pathogenesis, and analysis of viral reservoirs.
Journal of leukocyte biology Nov, 2006 | Pubmed ID: 16935944
Matrix metalloproteinases, their production by monocytes and macrophages and their potential role in HIV-related diseases.
Journal of leukocyte biology Nov, 2006 | Pubmed ID: 16959898
HIV-1 viral load assays for resource-limited settings.
PLoS medicine Oct, 2006 | Pubmed ID: 17032062
The mechanism underlying defective Fcgamma receptor-mediated phagocytosis by HIV-1-infected human monocyte-derived macrophages.
Journal of immunology (Baltimore, Md. : 1950) Jan, 2007 | Pubmed ID: 17202373
Changes in the V3 region of gp120 contribute to unusually broad coreceptor usage of an HIV-1 isolate from a CCR5 Delta32 heterozygote.
Virology May, 2007 | Pubmed ID: 17239419
The CD16+ monocyte subset is more permissive to infection and preferentially harbors HIV-1 in vivo.
Journal of immunology (Baltimore, Md. : 1950) May, 2007 | Pubmed ID: 17475889
CD16+ monocyte subset preferentially harbors HIV-1 and is expanded in pregnant Malawian women with Plasmodium falciparum malaria and HIV-1 infection.
The Journal of infectious diseases Jul, 2007 | Pubmed ID: 17538881
The heterosexual HIV type 1 epidemic in Papua New Guinea is dominated by subtype C.
AIDS research and human retroviruses Jul, 2007 | Pubmed ID: 17678479
Pathogenicity and immunogenicity of attenuated, nef-deleted HIV-1 strains in vivo.
Retrovirology , 2007 | Pubmed ID: 17888184
Use of an HIV-1 reverse-transcriptase enzyme-activity assay to measure HIV-1 viral load as a potential alternative to nucleic acid-based assay for monitoring antiretroviral therapy in resource-limited settings.
Journal of medical microbiology Dec, 2007 | Pubmed ID: 18033828
Reduction in hepatitis C-related liver disease associated with GB virus C in human immunodeficiency virus coinfection.
Gastroenterology Dec, 2007 | Pubmed ID: 18054555
Kynurenine pathway metabolism in human blood-brain-barrier cells: implications for immune tolerance and neurotoxicity.
Journal of neurochemistry May, 2008 | Pubmed ID: 18221377
Effects of HIV-1 infection in vitro on transendothelial migration by monocytes and monocyte-derived macrophages.
Journal of leukocyte biology Jun, 2009 | Pubmed ID: 19286896
Macrophages and residual HIV infection.
Current opinion in HIV and AIDS Mar, 2006 | Pubmed ID: 19372796
Enhanced monocyte Fc phagocytosis by a homologue of interleukin-10 encoded by human cytomegalovirus.
Virology Aug, 2009 | Pubmed ID: 19564031
Evaluation of the Cavidi ExaVir Load assay (version 3) for plasma human immunodeficiency virus type 1 load monitoring.
Journal of clinical microbiology Sep, 2009 | Pubmed ID: 19605583
Assessment of the low-cost Cavidi ExaVir Load assay for monitoring HIV viral load in pediatric and adult patients.
Journal of acquired immune deficiency syndromes (1999) Nov, 2009 | Pubmed ID: 19617845
Evaluation of the blood stabilizers TransFix and Cyto-Chex BCT for low-cost CD4 T-cell methodologies.
Viral immunology Oct, 2009 | Pubmed ID: 19811090
Effect of reverse transcriptase inhibitors and mutations on the low-cost Cavidi reverse transcriptase viral load assay.
Journal of acquired immune deficiency syndromes (1999) Dec, 2009 | Pubmed ID: 19901621
An HIV-1 integrase genotype assay for the detection of drug resistance mutations.
Sexual health Dec, 2009 | Pubmed ID: 19917199
The macrophage: the intersection between HIV infection and atherosclerosis.
Journal of leukocyte biology Apr, 2010 | Pubmed ID: 19952353
A novel, rapid method to detect infectious HIV-1 from plasma of persons infected with HIV-1.
Journal of virological methods Apr, 2010 | Pubmed ID: 20117138
Stability of dried blood spots for HIV-1 drug resistance analysis.
Current HIV research Mar, 2010 | Pubmed ID: 20163343
Decreased NK Cell FcRgamma in HIV-1 infected individuals receiving combination antiretroviral therapy: a cross sectional study.
PloS one , 2010 | Pubmed ID: 20224795
Quantifying HIV for monitoring antiretroviral therapy in resource-poor settings.
The Journal of infectious diseases Apr, 2010 | Pubmed ID: 20225942
Editorial: Monocyte subpopulations and lentiviral infection.
Journal of leukocyte biology Apr, 2010 | Pubmed ID: 20356904
Extremely prolonged HIV seroconversion associated with an MHC haplotype carrying disease susceptibility genes for antibody deficiency disorders.
Clinical immunology (Orlando, Fla.) Nov, 2010 | Pubmed ID: 20696618
HIV reverse transcriptase activity assay: a feasible surrogate for HIV viral load measurement in China.
Diagnostic microbiology and infectious disease Nov, 2010 | Pubmed ID: 20846816
HIV inhibits early signal transduction events triggered by CD16 cross-linking on NK cells, which are important for antibody-dependent cellular cytotoxicity.
Journal of leukocyte biology Jan, 2011 | Pubmed ID: 20884651
Both CD31(+) and CD31⁻ naive CD4(+) T cells are persistent HIV type 1-infected reservoirs in individuals receiving antiretroviral therapy.
The Journal of infectious diseases Dec, 2010 | Pubmed ID: 20979453
Point-of-care testing.
Current HIV/AIDS reports Mar, 2011 | Pubmed ID: 21184203
Biomarkers of immune dysfunction following combination antiretroviral therapy for HIV infection.
Biomarkers in medicine Apr, 2011 | Pubmed ID: 21473720
Symptomatic and asymptomatic early neurosyphilis in HIV-infected men who have sex with men: a retrospective case series from 2000 to 2007.
Sexual health Jun, 2011 | Pubmed ID: 21592435
Differential expression of CD163 on monocyte subsets in healthy and HIV-1 infected individuals.
PloS one , 2011 | Pubmed ID: 21625498
Antiviral activity of arbidol, a broad-spectrum drug for use against respiratory viruses, varies according to test conditions.
Journal of medical virology Jan, 2012 | Pubmed ID: 22028179
HIV infection and aging of the innate immune system.
Sexual health Dec, 2011 | Pubmed ID: 22127030
HIV infection induces age-related changes to monocytes and innate immune activation in young men that persist despite combination antiretroviral therapy.
AIDS (London, England) Apr, 2012 | Pubmed ID: 22313961
Endothelial cell activation promotes foam cell formation by monocytes following transendothelial migration in an in vitro model.
Experimental and molecular pathology Oct, 2012 | Pubmed ID: 22609311
Aging is associated with chronic innate immune activation and dysregulation of monocyte phenotype and function.
Aging cell Oct, 2012 | Pubmed ID: 22708967
Virologically suppressed HIV patients show activation of NK cells and persistent innate immune activation.
Journal of immunology (Baltimore, Md. : 1950) Aug, 2012 | Pubmed ID: 22745371
Evaluating new CD4 enumeration technologies for resource-constrained countries.
Nature reviews. Microbiology Nov, 2008 | Pubmed ID: 22745957
CRF01_AE dominates the HIV-1 epidemic in Indonesia.
Sexual health Nov, 2012 | Pubmed ID: 22958472
Are monocytes the canary in the coal mine for HIV-related atherosclerosis?
The Journal of infectious diseases Nov, 2012 | Pubmed ID: 23066161
Inhibition of telomerase activity by human immunodeficiency virus (HIV) nucleos(t)ide reverse transcriptase inhibitors: a potential factor contributing to HIV-associated accelerated aging.
The Journal of infectious diseases Apr, 2013 | Pubmed ID: 23303810
Age-associated changes in monocyte and innate immune activation markers occur more rapidly in HIV infected women.
PloS one , 2013 | Pubmed ID: 23365694
First molecular epidemiology study of Mycobacterium tuberculosis in Kiribati.
PloS one , 2013 | Pubmed ID: 23383187
Characterization of tetraspanins CD9, CD53, CD63, and CD81 in monocytes and macrophages in HIV-1 infection.
Journal of leukocyte biology Jun, 2013 | Pubmed ID: 23570947
HIV epidemic in men who have sex with men in Philippines.
The Lancet. Infectious diseases Jun, 2013 | Pubmed ID: 23718916
Associations between surface markers on blood monocytes and carotid atherosclerosis in HIV-positive individuals.
Immunology and cell biology Feb, 2014 | Pubmed ID: 24296810
Increased glucose metabolic activity is associated with CD4+ T-cell activation and depletion during chronic HIV infection.
AIDS (London, England) Jan, 2014 | Pubmed ID: 24335483
Acquisition of HIV by African-born residents of Victoria, Australia: insights from molecular epidemiology.
PloS one , 2013 | Pubmed ID: 24391866
Inflammatory co-morbidities in HIV+ individuals: learning lessons from healthy ageing.
Current HIV/AIDS reports Mar, 2014 | Pubmed ID: 24414166
Systematic review of the performance of HIV viral load technologies on plasma samples.
PloS one , 2014 | Pubmed ID: 24558359
Systematic review of the use of dried blood spots for monitoring HIV viral load and for early infant diagnosis.
PloS one , 2014 | Pubmed ID: 24603442
How does monocyte metabolism impact inflammation and aging during chronic HIV infection?
AIDS research and human retroviruses Apr, 2014 | Pubmed ID: 24697644
Presence of HIV drug resistance in antiretroviral therapy-naive and -experienced patients from Papua New Guinea.
The Journal of antimicrobial chemotherapy Aug, 2014 | Pubmed ID: 24722838
Monocytes as regulators of inflammation and HIV-related comorbidities during cART.
Journal of immunology research , 2014 | Pubmed ID: 25025081
The importance of monocytes and macrophages in HIV pathogenesis, treatment, and cure.
AIDS (London, England) Sep, 2014 | Pubmed ID: 25144219
Tuberculosis (TB)-associated immune reconstitution inflammatory syndrome in TB-HIV co-infected patients in Malaysia: prevalence, risk factors, and treatment outcomes.
Sexual health Dec, 2014 | Pubmed ID: 25200957
Macrophage migration inhibitory factor: a potential biomarker for cardiovascular disease in persons with HIV?
AIDS (London, England) Jul, 2014 | Pubmed ID: 25232902
Glucose transporter 1-expressing proinflammatory monocytes are elevated in combination antiretroviral therapy-treated and untreated HIV+ subjects.
Journal of immunology (Baltimore, Md. : 1950) Dec, 2014 | Pubmed ID: 25367121
C-reactive protein as a predictor of cardiovascular risk in HIV-infected individuals.
Sexual health Dec, 2014 | Pubmed ID: 25435195
Plasma interleukin-18 levels are a biomarker of innate immune responses that predict and characterize tuberculosis-associated immune reconstitution inflammatory syndrome.
AIDS (London, England) Feb, 2015 | Pubmed ID: 25565499
Viremic and Virologically Suppressed HIV Infection Increases Age-Related Changes to Monocyte Activation Equivalent to 12 and 4 Years of Aging, Respectively.
Journal of acquired immune deficiency syndromes (1999) May, 2015 | Pubmed ID: 25647525
Glucose metabolism regulates T cell activation, differentiation, and functions.
Frontiers in immunology , 2015 | Pubmed ID: 25657648
CD4 enumeration technologies: a systematic review of test performance for determining eligibility for antiretroviral therapy.
PloS one , 2015 | Pubmed ID: 25790185
The dire sexual health crisis among MSM in the Philippines: an exploding HIV epidemic in the absence of essential health services.
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases Aug, 2015 | Pubmed ID: 26072039
Quantitative Assessment of Intra-Patient Variation in CD4+ T Cell Counts in Stable, Virologically-Suppressed, HIV-Infected Subjects.
PloS one , 2015 | Pubmed ID: 26110761
Monocytes from HIV-infected individuals show impaired cholesterol efflux and increased foam cell formation after transendothelial migration.
AIDS (London, England) Jul, 2015 | Pubmed ID: 26244384
Factors Influencing Antiretroviral Adherence and Virological Outcomes in People Living with HIV in the Highlands of Papua New Guinea.
PloS one , 2015 | Pubmed ID: 26244516
Planning for the Next Global Pandemic.
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases Sep, 2015 | Pubmed ID: 26253461
Panobinostat clinical trial highlights the challenges towards an HIV cure.
The lancet. HIV Dec, 2014 | Pubmed ID: 26424118
Regulators of glucose metabolism in CD4(+) and CD8(+) T cells.
International reviews of immunology Nov, 2015 | Pubmed ID: 26606199
Aberrant Inflammasome Activation Characterizes Tuberculosis-Associated Immune Reconstitution Inflammatory Syndrome.
Journal of immunology (Baltimore, Md. : 1950) May, 2016 | Pubmed ID: 27076678
Emerging Role and Characterization of Immunometabolism: Relevance to HIV Pathogenesis, Serious Non-AIDS Events, and a Cure.
Journal of immunology (Baltimore, Md. : 1950) Jun, 2016 | Pubmed ID: 27207806
Glucose Metabolism in T Cells and Monocytes: New Perspectives in HIV Pathogenesis.
EBioMedicine Apr, 2016 | Pubmed ID: 27211546
Acceptability and feasibility of point-of-care CD4 testing on HIV continuum of care in low and middle income countries: a systematic review.
BMC health services research , 2016 | Pubmed ID: 27484023
Genetic polymorphisms in the CD14 gene are associated with monocyte activation and carotid intima-media thickness in HIV-infected patients on antiretroviral therapy.
Medicine Aug, 2016 | Pubmed ID: 27495090
Clovis S. Palmer1,2,3,
Joshua J. Anzinger4,
Tiffany R. Butterfield4,
Joseph M. McCune5,
Suzanne M. Crowe1,2,6
1Centre for Biomedical Research, Macfarlane Burnet Institute for Medical Research and Public Health,
2Department of Infectious Diseases, Monash University,
3Department of Microbiology and Immunology, University of Melbourne,
4Department of Microbiology, The University of the West Indies,
5Division of Experimental Medicine, Department of Medicine, University of California, San Francisco,
6Department of Medicine, Monash University
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