Department of Occupational and Environmental Health,
Department of Environmental Health,
Fay W. Boozman School of Public Health,
Department of Environmental Health, Fay W. Boozman School of Public Health
Igor Koturbash has not added Biography.
If you are Igor Koturbash and would like to personalize this page please email our Author Liaison for assistance.
Stable loss of global DNA methylation in the radiation-target tissue--a possible mechanism contributing to radiation carcinogenesis?
Biochemical and biophysical research communications Nov, 2005 | Pubmed ID: 16202973
Fractionated low-dose radiation exposure leads to accumulation of DNA damage and profound alterations in DNA and histone methylation in the murine thymus.
Molecular cancer research : MCR Oct, 2005 | Pubmed ID: 16254189
Novel retinoblastoma binding protein RBBP9 modulates sex-specific radiation responses in vivo.
Carcinogenesis Mar, 2006 | Pubmed ID: 16272168
Epigenetic dysregulation underlies radiation-induced transgenerational genome instability in vivo.
International journal of radiation oncology, biology, physics Oct, 2006 | Pubmed ID: 16965987
Radiation-induced molecular changes in rat mammary tissue: possible implications for radiation-induced carcinogenesis.
International journal of radiation biology Nov, 2006 | Pubmed ID: 17148264
Role of epigenetic effectors in maintenance of the long-term persistent bystander effect in spleen in vivo.
Carcinogenesis Aug, 2007 | Pubmed ID: 17347136
DNA double-strand breaks form in bystander cells after microbeam irradiation of three-dimensional human tissue models.
Cancer research May, 2007 | Pubmed ID: 17483342
Germ-line mutations, DNA damage, and global hypermethylation in mice exposed to particulate air pollution in an urban/industrial location.
Proceedings of the National Academy of Sciences of the United States of America Jan, 2008 | Pubmed ID: 18195365
In vivo bystander effect: cranial X-irradiation leads to elevated DNA damage, altered cellular proliferation and apoptosis, and increased p53 levels in shielded spleen.
International journal of radiation oncology, biology, physics Feb, 2008 | Pubmed ID: 18207032
Paternal cranial irradiation induces distant bystander DNA damage in the germline and leads to epigenetic alterations in the offspring.
Cell cycle (Georgetown, Tex.) May, 2008 | Pubmed ID: 18418050
Radiation-induced bystander effects in vivo are sex specific.
Mutation research Jul, 2008 | Pubmed ID: 18508093
Sex-specific microRNAome deregulation in the shielded bystander spleen of cranially exposed mice.
Cell cycle (Georgetown, Tex.) Jun, 2008 | Pubmed ID: 18560276
Altered microRNA expression patterns in irradiated hematopoietic tissues suggest a sex-specific protective mechanism.
Biochemical and biophysical research communications Dec, 2008 | Pubmed ID: 18823940
DNA damage-induced upregulation of miR-709 in the germline downregulates BORIS to counteract aberrant DNA hypomethylation.
Cell cycle (Georgetown, Tex.) Dec, 2008 | Pubmed ID: 19029807
Radiation-induced bystander effects in vivo are epigenetically regulated in a tissue-specific manner.
Environmental and molecular mutagenesis Mar, 2009 | Pubmed ID: 19107897
Heat-killed bacteria induce genome instability in mouse small intestine, liver and spleen tissues.
Cell cycle (Georgetown, Tex.) Jun, 2009 | Pubmed ID: 19440049
Hypomethylation and genome instability in the germline of exposed parents and their progeny is associated with altered miRNA expression.
Carcinogenesis Jun, 2010 | Pubmed ID: 19959559
Small molecules with big effects: the role of the microRNAome in cancer and carcinogenesis.
Mutation research Jun, 2011 | Pubmed ID: 20472093
Sex-specific radiation-induced microRNAome responses in the hippocampus, cerebellum and frontal cortex in a mouse model.
Mutation research Jun, 2011 | Pubmed ID: 20478395
Imbalance between apoptosis and cell proliferation during early stages of mammary gland carcinogenesis in ACI rats.
Mutation research Dec, 2010 | Pubmed ID: 20659487
Reversibility of pre-malignant estrogen-induced epigenetic changes.
Cell cycle (Georgetown, Tex.) Aug, 2010 | Pubmed ID: 20699652
Epigenetic alterations in liver of C57BL/6J mice after short-term inhalational exposure to 1,3-butadiene.
Environmental health perspectives May, 2011 | Pubmed ID: 21147608
Role of epigenetic events in chemical carcinogenesis--a justification for incorporating epigenetic evaluations in cancer risk assessment.
Toxicology mechanisms and methods May, 2011 | Pubmed ID: 21495867
Epigenetic mechanisms of mouse interstrain variability in genotoxicity of the environmental toxicant 1,3-butadiene.
Toxicological sciences : an official journal of the Society of Toxicology Aug, 2011 | Pubmed ID: 21602187
Induction and persistence of radiation-induced DNA damage is more pronounced in young animals than in old animals.
Aging Jun, 2011 | Pubmed ID: 21685513
Chronic administration of 2-acetylaminofluorene alters the cellular iron metabolism in rat liver.
Toxicological sciences : an official journal of the Society of Toxicology Oct, 2011 | Pubmed ID: 21785164
Alterations in histone H4 lysine 20 methylation: implications for cancer detection and prevention.
Antioxidants & redox signaling Jul, 2012 | Pubmed ID: 22035019
Role of epigenetic and miR-22 and miR-29b alterations in the downregulation of Mat1a and Mthfr genes in early preneoplastic livers in rats induced by 2-acetylaminofluorene.
Molecular carcinogenesis Dec, 2011 | Pubmed ID: 22213190
Tumorigenicity of acrylamide and its metabolite glycidamide in the neonatal mouse bioassay.
International journal of cancer Nov, 2012 | Pubmed ID: 22336951
Role of microRNAs in the regulation of drug metabolizing and transporting genes and the response to environmental toxicants.
Expert opinion on drug metabolism & toxicology May, 2012 | Pubmed ID: 22435483
Interstrain differences in the severity of liver injury induced by a choline- and folate-deficient diet in mice are associated with dysregulation of genes involved in lipid metabolism.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Nov, 2012 | Pubmed ID: 22872676
The chemopreventive activity of the butyric acid prodrug tributyrin in experimental rat hepatocarcinogenesis is associated with p53 acetylation and activation of the p53 apoptotic signaling pathway.
Carcinogenesis Aug, 2013 | Pubmed ID: 23568954
Epigenetic alterations induced by ambient particulate matter in mouse macrophages.
Environmental and molecular mutagenesis Jun, 2014 | Pubmed ID: 24535919
Long-term epigenetic effects of exposure to low doses of 56Fe in the mouse lung.
Journal of radiation research Jul, 2014 | Pubmed ID: 24585548
Exposure to low-dose (56)Fe-ion radiation induces long-term epigenetic alterations in mouse bone marrow hematopoietic progenitor and stem cells.
Radiation research Jul, 2014 | Pubmed ID: 24960414
The hypothalamic-pituitary-thyroid axis in infants and children: protection from radioiodines.
Journal of thyroid research , 2014 | Pubmed ID: 24971190
Age-dependent changes in DNA repair in radiation-exposed mice.
Radiation research Dec, 2014 | Pubmed ID: 25409128
Whole-body proton irradiation causes long-term damage to hematopoietic stem cells in mice.
Radiation research Feb, 2015 | Pubmed ID: 25635345
Effects of oral exposure to bisphenol A on gene expression and global genomic DNA methylation in the prostate, female mammary gland, and uterus of NCTR Sprague-Dawley rats.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association Jul, 2015 | Pubmed ID: 25862956
Short-term exposure to engineered nanomaterials affects cellular epigenome.
Nanotoxicology , 2016 | Pubmed ID: 25938281
Effects of Laser Printer-Emitted Engineered Nanoparticles on Cytotoxicity, Chemokine Expression, Reactive Oxygen Species, DNA Methylation, and DNA Damage: A Comprehensive in Vitro Analysis in Human Small Airway Epithelial Cells, Macrophages, and Lymphoblasts.
Environmental health perspectives Feb, 2016 | Pubmed ID: 26080392
The impact of low-dose carcinogens and environmental disruptors on tissue invasion and metastasis.
Carcinogenesis Jun, 2015 | Pubmed ID: 26106135
Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead.
Carcinogenesis Jun, 2015 | Pubmed ID: 26106142
Importance of investigating epigenetic alterations for industry and regulators: An appraisal of current efforts by the Health and Environmental Sciences Institute.
Toxicology Sep, 2015 | Pubmed ID: 26134581
Response of transposable elements to environmental stressors.
Mutation research. Reviews in mutation research Jul-Sep, 2015 | Pubmed ID: 26281766
In Vitro Toxicity and Epigenotoxicity of Different Types of Ambient Particulate Matter.
Toxicological sciences : an official journal of the Society of Toxicology Dec, 2015 | Pubmed ID: 26342214
The Fine LINE: Methylation Drawing the Cancer Landscape.
BioMed research international , 2015 | Pubmed ID: 26448926
microRNAs as pharmacogenomic biomarkers for drug efficacy and drug safety assessment.
Biomarkers in medicine , 2015 | Pubmed ID: 26501795
Combined exposure to protons and (56)Fe leads to overexpression of Il13 and reactivation of repetitive elements in the mouse lung.
Life sciences in space research Nov, 2015 | Pubmed ID: 26553631
In vivo epigenetic effects induced by engineered nanomaterials: A case study of copper oxide and laser printer-emitted engineered nanoparticles.
Nanotoxicology , 2016 | Pubmed ID: 26559097
Space radiation and cardiovascular disease risk.
World journal of cardiology Dec, 2015 | Pubmed ID: 26730293
A priming dose of protons alters the early cardiac cellular and molecular response to (56)Fe irradiation.
Life sciences in space research Feb, 2016 | Pubmed ID: 26948008
Radiation-induced changes in DNA methylation of repetitive elements in the mouse heart.
Mutation research May, 2016 | Pubmed ID: 26963372
Effects of intratracheally instilled laser printer-emitted engineered nanoparticles in a mouse model: A case study of toxicological implications from nanomaterials released during consumer use.
NanoImpact Jan, 2016 | Pubmed ID: 26989787
The Vitamin E Analog Gamma-Tocotrienol (GT3) Suppresses Radiation-Induced Cytogenetic Damage.
Pharmaceutical research Sep, 2016 | Pubmed ID: 27216753
Densely ionizing radiation affects DNA methylation of selective LINE-1 elements.
Environmental research Oct, 2016 | Pubmed ID: 27419368
Fractionated exposure to low doses of ionizing radiation results in accumulation of DNA damage in mouse spleen tissue and activation of apoptosis in a p53/Atm-independent manner.
International journal of radiation biology Oct, 2016 | Pubmed ID: 27758128
Pediatric Exposures to Ionizing Radiation: Carcinogenic Considerations.
International journal of environmental research and public health Oct, 2016 | Pubmed ID: 27801855
Effects of ionizing radiation on the heart.
Mutation research Oct - Dec, 2016 | Pubmed ID: 27919338
1Division of Radiation Health, Department of Pharmaceutical Sciences, College of Pharmacy, University of Arkansas for Medical Sciences,
2Department of Environmental Health, Fay W. Boozman School of Public Health, University of Arkansas for Medical Sciences,
3Surgical Service, Central Arkansas Veterans Healthcare System
关于 JoVE
版权所属 © 2024 MyJoVE 公司版权所有,本公司不涉及任何医疗业务和医疗服务。