Corporate Preclinical R&D
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Antitumor activity of edotecarin in breast carcinoma models.
Cancer chemotherapy and pharmacology Jul, 2007 | Pubmed ID: 17089166
In vivo imaging of early stage apoptosis by measuring real-time caspase-3/7 activation.
Apoptosis : an international journal on programmed cell death Feb, 2011 | Pubmed ID: 21082356
Imaging pulmonary NF-kappaB activation and therapeutic effects of MLN120B and TDZD-8.
PloS one , 2011 | Pubmed ID: 21966423
In vivo imaging of transiently transgenized mice with a bovine interleukin 8 (CXCL8) promoter/luciferase reporter construct.
PloS one , 2012 | Pubmed ID: 22761878
Enlightened Mannhemia haemolytica lung inflammation in bovinized mice.
Veterinary research Jan, 2014 | Pubmed ID: 24460618
In vivo image analysis of BoHV-4-based vector in mice.
PloS one , 2014 | Pubmed ID: 24752229
Generation and characterization of the first immortalized alpaca cell line suitable for diagnostic and immunization studies.
PloS one , 2014 | Pubmed ID: 25140515
Azithromycin inhibits nuclear factor-κB activation during lung inflammation: an in vivo imaging study.
Pharmacology research & perspectives Oct, 2014 | Pubmed ID: 25505605
CHF6001 II: a novel phosphodiesterase 4 inhibitor, suitable for topical pulmonary administration--in vivo preclinical pharmacology profile defines a potent anti-inflammatory compound with a wide therapeutic window.
The Journal of pharmacology and experimental therapeutics Mar, 2015 | Pubmed ID: 25576073
In vivo imaging of the lung inflammatory response to Pseudomonas aeruginosa and its modulation by azithromycin.
Journal of translational medicine Aug, 2015 | Pubmed ID: 26239109
Monitoring inflammation and airway remodeling by fluorescence molecular tomography in a chronic asthma model.
Journal of translational medicine Oct, 2015 | Pubmed ID: 26496719
Assessment of asthmatic inflammation using hybrid fluorescence molecular tomography-x-ray computed tomography.
Journal of biomedical optics Jan, 2016 | Pubmed ID: 26803669
In vivo monitoring of lung inflammation in CFTR-deficient mice.
Journal of translational medicine Jul, 2016 | Pubmed ID: 27468800
Heterologous Matrix Metalloproteinase Gene Promoter Activity Allows In Vivo Real-time Imaging of Bleomycin-Induced Lung Fibrosis in Transiently Transgenized Mice.
Frontiers in immunology , 2017 | Pubmed ID: 28298912
Gabriella Bergamini*,1,
Fabio Stellari*,2,
Angela Sandri*,3,
Maria M. Lleo3,
Gaetano Donofrio4,
Francesca Ruscitti5,2,
Federico Boschi6,
Andrea Sbarbati7,
Gino Villetti2,
Paola Melotti8,
Claudio Sorio1
1Department of Medicine, General Pathology Division, Cystic Fibrosis Translational Research Laboratory "D. Lissandrini", University of Verona,
2Corporate Preclinical R&D, Chiesi Farmaceutici S.p.A.,
3Department of Diagnostic and Public Health, Microbiology Division, University of Verona,
4Dipartimento di Scienze Medico-Veterinarie, University of Parma,
5Department of Biomedical Biotechnological and Translational Sciences, University of Parma,
6Department of Computer Science, University of Verona,
7Department of Neurological, Biomedical and Movement Sciences, University of Verona,
8Cystic Fibrosis Regional Center (CFC), AOUI Verona
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