Jean Gruenberg

Late endosome motility depends on lipids via the small GTPase Rab7.

Separation and characterization of late endosomal membrane domains.

Sonic hedgehog induces the segregation of patched and smoothened in endosomes.

Oiling the wheels of the endocytic pathway.

Signaling from the far side.

Modulation of Rab5 and Rab7 recruitment to phagosomes by phosphatidylinositol 3-kinase.

Sliding doors: clathrin-coated pits or caveolae?

Annexin II regulates multivesicular endosome biogenesis in the degradation pathway of animal cells.

Lipids in endocytic membrane transport and sorting.

The trans-membrane protein p25 forms highly specialized domains that regulate membrane composition and dynamics.

Role of LBPA and Alix in multivesicular liposome formation and endosome organization.

The biogenesis of multivesicular endosomes.

Acquisition of Hrs, an essential component of phagosomal maturation, is impaired by mycobacteria.

ARF1 regulates Nef-induced CD4 degradation.

The secreted form of dengue virus nonstructural protein NS1 is endocytosed by hepatocytes and accumulates in late endosomes: implications for viral infectivity.

Concise synthesis of ether analogues of lysobisphosphatidic acid.

[Endocytosis: the Trojan Horse of viral infection].

Capture of the small GTPase Rab5 by GDI: regulation by p38 MAP kinase.

Toxoplasma: guess who's coming to dinner.

Mechanisms of pathogen entry through the endosomal compartments.

Intra-endosomal membrane traffic.

Intracellular trafficking of interleukin-1 receptor I requires Tollip.

Diversity of raft-like domains in late endosomes.

Core protein machinery for mammalian phosphatidylinositol 3,5-bisphosphate synthesis and turnover that regulates the progression of endosomal transport. Novel Sac phosphatase joins the ArPIKfyve-PIKfyve complex.

Late endosomal cholesterol accumulation leads to impaired intra-endosomal trafficking.

The p11/S100A10 light chain of annexin A2 is dispensable for annexin A2 association to endosomes and functions in endosomal transport.

The redox sensor TXNL1 plays a regulatory role in fluid phase endocytosis.

The cargo receptors Surf4, endoplasmic reticulum-Golgi intermediate compartment (ERGIC)-53, and p25 are required to maintain the architecture of ERGIC and Golgi.

Subcellular fractionation of tissue culture cells.

Subcellular fractionation of tissue culture cells.

Down syndrome fibroblast model of Alzheimer-related endosome pathology: accelerated endocytosis promotes late endocytic defects.

Lysobisphosphatidic acid controls endosomal cholesterol levels.

Hrs and SNX3 functions in sorting and membrane invagination within multivesicular bodies.

In vitro budding of intralumenal vesicles into late endosomes is regulated by Alix and Tsg101.

The ESCRT-I subunit TSG101 controls endosome-to-cytosol release of viral RNA.

Annexin A2 binding to endosomes and functions in endosomal transport are regulated by tyrosine 23 phosphorylation.

Molecular assemblies and membrane domains in multivesicular endosome dynamics.

Annexin A2-dependent polymerization of actin mediates endosome biogenesis.

Viruses and endosome membrane dynamics.

Ion flux and the function of endosomes and lysosomes: pH is just the start: the flux of ions across endosomal membranes influences endosome function not only through regulation of the luminal pH.

Role of AP1 and Gadkin in the traffic of secretory endo-lysosomes.

Role of SNX16 in the dynamics of tubulo-cisternal membrane domains of late endosomes.

Regulation of the MVB pathway by SCAMP3.

Duelling functions of the V-ATPase.

A novel strategy to identify drugs that interfere with endosomal lipids.

Studying lipids involved in the endosomal pathway.

Regulation of the EGF transcriptional response by endocytic sorting.

Single-cell analysis of population context advances RNAi screening at multiple levels.

SNX12 role in endosome membrane transport.

An MBoC favorite: Functional interactions between sphingolipids and sterols in biological membranes regulating cell physiology.

PNPLA3/adiponutrin functions in lipid droplet formation.

Viral infection controlled by a calcium-dependent lipid-binding module in ALIX.

Lipid sorting and multivesicular endosome biogenesis.

ALIX and the multivesicular endosome: ALIX in Wonderland.

Endosome maturation, transport and functions.

Discovery of novel membrane binding structures and functions.

Close encounter of the third kind: the ER meets endosomes at fission sites.

Wnt directs the endosomal flux of LDL-derived cholesterol and lipid droplet homeostasis.

Secondary structure and (1)H, (13)C, (15)N resonance assignments of the endosomal sorting protein sorting nexin 3.

Selective Imaging of Late Endosomes with a pH-Sensitive Diazaoxatriangulene Fluorescent Probe.

Moesin and cortactin control actin-dependent multivesicular endosome biogenesis.

The Biochemistry Department of the University of Geneva: Understanding the Molecular Basis and Function of Intracellular Organization.

Automated Microscopy and High Content Screens (Phenotypic Screens) in Academia Labs.

LLOMe does not release cysteine cathepsins to the cytosol but inactivates them in transiently permeabilized lysosomes.