Department of Biochemistry
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Late endosome motility depends on lipids via the small GTPase Rab7.
The EMBO journal Mar, 2002 | Pubmed ID: 11889035
Separation and characterization of late endosomal membrane domains.
The Journal of biological chemistry Aug, 2002 | Pubmed ID: 12065580
Sonic hedgehog induces the segregation of patched and smoothened in endosomes.
Current biology : CB Jun, 2002 | Pubmed ID: 12123571
Oiling the wheels of the endocytic pathway.
Trends in cell biology Jul, 2002 | Pubmed ID: 12185843
Signaling from the far side.
Molecular cell Dec, 2002 | Pubmed ID: 12503999
Modulation of Rab5 and Rab7 recruitment to phagosomes by phosphatidylinositol 3-kinase.
Molecular and cellular biology Apr, 2003 | Pubmed ID: 12640132
Sliding doors: clathrin-coated pits or caveolae?
Nature cell biology May, 2003 | Pubmed ID: 12724770
Annexin II regulates multivesicular endosome biogenesis in the degradation pathway of animal cells.
The EMBO journal Jul, 2003 | Pubmed ID: 12839987
Lipids in endocytic membrane transport and sorting.
Current opinion in cell biology Aug, 2003 | Pubmed ID: 12892777
The trans-membrane protein p25 forms highly specialized domains that regulate membrane composition and dynamics.
Journal of cell science Dec, 2003 | Pubmed ID: 14600267
Role of LBPA and Alix in multivesicular liposome formation and endosome organization.
Science (New York, N.Y.) Jan, 2004 | Pubmed ID: 14739459
The biogenesis of multivesicular endosomes.
Nature reviews. Molecular cell biology Apr, 2004 | Pubmed ID: 15071556
Acquisition of Hrs, an essential component of phagosomal maturation, is impaired by mycobacteria.
Molecular and cellular biology May, 2004 | Pubmed ID: 15121875
ARF1 regulates Nef-induced CD4 degradation.
Current biology : CB Jun, 2004 | Pubmed ID: 15202998
The secreted form of dengue virus nonstructural protein NS1 is endocytosed by hepatocytes and accumulates in late endosomes: implications for viral infectivity.
Journal of virology Sep, 2005 | Pubmed ID: 16103191
Concise synthesis of ether analogues of lysobisphosphatidic acid.
Organic letters Sep, 2005 | Pubmed ID: 16119911
[Endocytosis: the Trojan Horse of viral infection].
Medecine sciences : M/S Nov, 2005 | Pubmed ID: 16274637
Capture of the small GTPase Rab5 by GDI: regulation by p38 MAP kinase.
Methods in enzymology , 2005 | Pubmed ID: 16473603
Toxoplasma: guess who's coming to dinner.
Cell Apr, 2006 | Pubmed ID: 16630810
Mechanisms of pathogen entry through the endosomal compartments.
Nature reviews. Molecular cell biology Jul, 2006 | Pubmed ID: 16773132
Intra-endosomal membrane traffic.
Trends in cell biology Oct, 2006 | Pubmed ID: 16949287
Intracellular trafficking of interleukin-1 receptor I requires Tollip.
Current biology : CB Nov, 2006 | Pubmed ID: 17113392
Diversity of raft-like domains in late endosomes.
PloS one Apr, 2007 | Pubmed ID: 17460758
Core protein machinery for mammalian phosphatidylinositol 3,5-bisphosphate synthesis and turnover that regulates the progression of endosomal transport. Novel Sac phosphatase joins the ArPIKfyve-PIKfyve complex.
The Journal of biological chemistry Aug, 2007 | Pubmed ID: 17556371
Late endosomal cholesterol accumulation leads to impaired intra-endosomal trafficking.
PloS one Sep, 2007 | Pubmed ID: 17786222
The p11/S100A10 light chain of annexin A2 is dispensable for annexin A2 association to endosomes and functions in endosomal transport.
PloS one Oct, 2007 | Pubmed ID: 17971878
The redox sensor TXNL1 plays a regulatory role in fluid phase endocytosis.
PloS one Nov, 2007 | Pubmed ID: 17987124
The cargo receptors Surf4, endoplasmic reticulum-Golgi intermediate compartment (ERGIC)-53, and p25 are required to maintain the architecture of ERGIC and Golgi.
Molecular biology of the cell May, 2008 | Pubmed ID: 18287528
Subcellular fractionation of tissue culture cells.
Current protocols in protein science Aug, 2004 | Pubmed ID: 18429269
Subcellular fractionation of tissue culture cells.
Current protocols in immunology Nov, 2003 | Pubmed ID: 18432914
Down syndrome fibroblast model of Alzheimer-related endosome pathology: accelerated endocytosis promotes late endocytic defects.
The American journal of pathology Aug, 2008 | Pubmed ID: 18535180
Lysobisphosphatidic acid controls endosomal cholesterol levels.
The Journal of biological chemistry Oct, 2008 | Pubmed ID: 18644787
Hrs and SNX3 functions in sorting and membrane invagination within multivesicular bodies.
PLoS biology Sep, 2008 | Pubmed ID: 18767904
In vitro budding of intralumenal vesicles into late endosomes is regulated by Alix and Tsg101.
Molecular biology of the cell Nov, 2008 | Pubmed ID: 18768755
The ESCRT-I subunit TSG101 controls endosome-to-cytosol release of viral RNA.
Traffic (Copenhagen, Denmark) Dec, 2008 | Pubmed ID: 18817529
Annexin A2 binding to endosomes and functions in endosomal transport are regulated by tyrosine 23 phosphorylation.
The Journal of biological chemistry Jan, 2009 | Pubmed ID: 18990701
Molecular assemblies and membrane domains in multivesicular endosome dynamics.
Experimental cell research May, 2009 | Pubmed ID: 19133258
Annexin A2-dependent polymerization of actin mediates endosome biogenesis.
Developmental cell Mar, 2009 | Pubmed ID: 19289089
Viruses and endosome membrane dynamics.
Current opinion in cell biology Aug, 2009 | Pubmed ID: 19443190
Ion flux and the function of endosomes and lysosomes: pH is just the start: the flux of ions across endosomal membranes influences endosome function not only through regulation of the luminal pH.
BioEssays : news and reviews in molecular, cellular and developmental biology Feb, 2011 | Pubmed ID: 21140470
Role of AP1 and Gadkin in the traffic of secretory endo-lysosomes.
Molecular biology of the cell Jun, 2011 | Pubmed ID: 21525240
Role of SNX16 in the dynamics of tubulo-cisternal membrane domains of late endosomes.
PloS one , 2011 | Pubmed ID: 21754999
Regulation of the MVB pathway by SCAMP3.
Traffic (Copenhagen, Denmark) Jan, 2012 | Pubmed ID: 21951651
Duelling functions of the V-ATPase.
The EMBO journal Oct, 2011 | Pubmed ID: 22009224
A novel strategy to identify drugs that interfere with endosomal lipids.
Chimia , 2011 | Pubmed ID: 22289369
Studying lipids involved in the endosomal pathway.
Methods in cell biology , 2012 | Pubmed ID: 22325596
Regulation of the EGF transcriptional response by endocytic sorting.
Science signaling Mar, 2012 | Pubmed ID: 22416276
Single-cell analysis of population context advances RNAi screening at multiple levels.
Molecular systems biology Apr, 2012 | Pubmed ID: 22531119
SNX12 role in endosome membrane transport.
PloS one , 2012 | Pubmed ID: 22719997
An MBoC favorite: Functional interactions between sphingolipids and sterols in biological membranes regulating cell physiology.
Molecular biology of the cell Jul, 2012 | Pubmed ID: 22745339
PNPLA3/adiponutrin functions in lipid droplet formation.
Biology of the cell May, 2013 | Pubmed ID: 23398201
Viral infection controlled by a calcium-dependent lipid-binding module in ALIX.
Developmental cell May, 2013 | Pubmed ID: 23664863
Lipid sorting and multivesicular endosome biogenesis.
Cold Spring Harbor perspectives in biology Oct, 2013 | Pubmed ID: 24086044
ALIX and the multivesicular endosome: ALIX in Wonderland.
Trends in cell biology Jan, 2014 | Pubmed ID: 24287454
Endosome maturation, transport and functions.
Seminars in cell & developmental biology Jul, 2014 | Pubmed ID: 24709024
Discovery of novel membrane binding structures and functions.
Biochemistry and cell biology = Biochimie et biologie cellulaire Dec, 2014 | Pubmed ID: 25394204
Close encounter of the third kind: the ER meets endosomes at fission sites.
Developmental cell Dec, 2014 | Pubmed ID: 25535914
Wnt directs the endosomal flux of LDL-derived cholesterol and lipid droplet homeostasis.
EMBO reports Jun, 2015 | Pubmed ID: 25851648
Secondary structure and (1)H, (13)C, (15)N resonance assignments of the endosomal sorting protein sorting nexin 3.
Biomolecular NMR assignments Oct, 2015 | Pubmed ID: 25893673
Selective Imaging of Late Endosomes with a pH-Sensitive Diazaoxatriangulene Fluorescent Probe.
Journal of the American Chemical Society Feb, 2016 | Pubmed ID: 26799309
Moesin and cortactin control actin-dependent multivesicular endosome biogenesis.
Molecular biology of the cell Nov, 2016 | Pubmed ID: 27605702
The Biochemistry Department of the University of Geneva: Understanding the Molecular Basis and Function of Intracellular Organization.
Chimia Dec, 2009 | Pubmed ID: 28372605
Automated Microscopy and High Content Screens (Phenotypic Screens) in Academia Labs.
Chimia Dec, 2016 | Pubmed ID: 28661361
LLOMe does not release cysteine cathepsins to the cytosol but inactivates them in transiently permeabilized lysosomes.
Journal of cell science Jul, 2017 | Pubmed ID: 28754686