Department of Biochemistry
Jean Gruenberg has not added Biography.
If you are Jean Gruenberg and would like to personalize this page please email our Author Liaison for assistance.
Late endosome motility depends on lipids via the small GTPase Rab7.
The EMBO journal Mar, 2002 | Pubmed ID: 11889035
Separation and characterization of late endosomal membrane domains.
The Journal of biological chemistry Aug, 2002 | Pubmed ID: 12065580
Sonic hedgehog induces the segregation of patched and smoothened in endosomes.
Current biology : CB Jun, 2002 | Pubmed ID: 12123571
Oiling the wheels of the endocytic pathway.
Trends in cell biology Jul, 2002 | Pubmed ID: 12185843
Signaling from the far side.
Molecular cell Dec, 2002 | Pubmed ID: 12503999
Modulation of Rab5 and Rab7 recruitment to phagosomes by phosphatidylinositol 3-kinase.
Molecular and cellular biology Apr, 2003 | Pubmed ID: 12640132
Sliding doors: clathrin-coated pits or caveolae?
Nature cell biology May, 2003 | Pubmed ID: 12724770
Annexin II regulates multivesicular endosome biogenesis in the degradation pathway of animal cells.
The EMBO journal Jul, 2003 | Pubmed ID: 12839987
Lipids in endocytic membrane transport and sorting.
Current opinion in cell biology Aug, 2003 | Pubmed ID: 12892777
The trans-membrane protein p25 forms highly specialized domains that regulate membrane composition and dynamics.
Journal of cell science Dec, 2003 | Pubmed ID: 14600267
Role of LBPA and Alix in multivesicular liposome formation and endosome organization.
Science (New York, N.Y.) Jan, 2004 | Pubmed ID: 14739459
The biogenesis of multivesicular endosomes.
Nature reviews. Molecular cell biology Apr, 2004 | Pubmed ID: 15071556
Acquisition of Hrs, an essential component of phagosomal maturation, is impaired by mycobacteria.
Molecular and cellular biology May, 2004 | Pubmed ID: 15121875
ARF1 regulates Nef-induced CD4 degradation.
Current biology : CB Jun, 2004 | Pubmed ID: 15202998
The secreted form of dengue virus nonstructural protein NS1 is endocytosed by hepatocytes and accumulates in late endosomes: implications for viral infectivity.
Journal of virology Sep, 2005 | Pubmed ID: 16103191
Concise synthesis of ether analogues of lysobisphosphatidic acid.
Organic letters Sep, 2005 | Pubmed ID: 16119911
[Endocytosis: the Trojan Horse of viral infection].
Medecine sciences : M/S Nov, 2005 | Pubmed ID: 16274637
Capture of the small GTPase Rab5 by GDI: regulation by p38 MAP kinase.
Methods in enzymology , 2005 | Pubmed ID: 16473603
Toxoplasma: guess who's coming to dinner.
Cell Apr, 2006 | Pubmed ID: 16630810
Mechanisms of pathogen entry through the endosomal compartments.
Nature reviews. Molecular cell biology Jul, 2006 | Pubmed ID: 16773132
Intra-endosomal membrane traffic.
Trends in cell biology Oct, 2006 | Pubmed ID: 16949287
Intracellular trafficking of interleukin-1 receptor I requires Tollip.
Current biology : CB Nov, 2006 | Pubmed ID: 17113392
Diversity of raft-like domains in late endosomes.
PloS one Apr, 2007 | Pubmed ID: 17460758
Core protein machinery for mammalian phosphatidylinositol 3,5-bisphosphate synthesis and turnover that regulates the progression of endosomal transport. Novel Sac phosphatase joins the ArPIKfyve-PIKfyve complex.
The Journal of biological chemistry Aug, 2007 | Pubmed ID: 17556371
Late endosomal cholesterol accumulation leads to impaired intra-endosomal trafficking.
PloS one Sep, 2007 | Pubmed ID: 17786222
The p11/S100A10 light chain of annexin A2 is dispensable for annexin A2 association to endosomes and functions in endosomal transport.
PloS one Oct, 2007 | Pubmed ID: 17971878
The redox sensor TXNL1 plays a regulatory role in fluid phase endocytosis.
PloS one Nov, 2007 | Pubmed ID: 17987124
The cargo receptors Surf4, endoplasmic reticulum-Golgi intermediate compartment (ERGIC)-53, and p25 are required to maintain the architecture of ERGIC and Golgi.
Molecular biology of the cell May, 2008 | Pubmed ID: 18287528
Subcellular fractionation of tissue culture cells.
Current protocols in protein science Aug, 2004 | Pubmed ID: 18429269
Subcellular fractionation of tissue culture cells.
Current protocols in immunology Nov, 2003 | Pubmed ID: 18432914
Down syndrome fibroblast model of Alzheimer-related endosome pathology: accelerated endocytosis promotes late endocytic defects.
The American journal of pathology Aug, 2008 | Pubmed ID: 18535180
Lysobisphosphatidic acid controls endosomal cholesterol levels.
The Journal of biological chemistry Oct, 2008 | Pubmed ID: 18644787
Hrs and SNX3 functions in sorting and membrane invagination within multivesicular bodies.
PLoS biology Sep, 2008 | Pubmed ID: 18767904
In vitro budding of intralumenal vesicles into late endosomes is regulated by Alix and Tsg101.
Molecular biology of the cell Nov, 2008 | Pubmed ID: 18768755
The ESCRT-I subunit TSG101 controls endosome-to-cytosol release of viral RNA.
Traffic (Copenhagen, Denmark) Dec, 2008 | Pubmed ID: 18817529
Annexin A2 binding to endosomes and functions in endosomal transport are regulated by tyrosine 23 phosphorylation.
The Journal of biological chemistry Jan, 2009 | Pubmed ID: 18990701
Molecular assemblies and membrane domains in multivesicular endosome dynamics.
Experimental cell research May, 2009 | Pubmed ID: 19133258
Annexin A2-dependent polymerization of actin mediates endosome biogenesis.
Developmental cell Mar, 2009 | Pubmed ID: 19289089
Viruses and endosome membrane dynamics.
Current opinion in cell biology Aug, 2009 | Pubmed ID: 19443190
Ion flux and the function of endosomes and lysosomes: pH is just the start: the flux of ions across endosomal membranes influences endosome function not only through regulation of the luminal pH.
BioEssays : news and reviews in molecular, cellular and developmental biology Feb, 2011 | Pubmed ID: 21140470
Role of AP1 and Gadkin in the traffic of secretory endo-lysosomes.
Molecular biology of the cell Jun, 2011 | Pubmed ID: 21525240
Role of SNX16 in the dynamics of tubulo-cisternal membrane domains of late endosomes.
PloS one , 2011 | Pubmed ID: 21754999
Regulation of the MVB pathway by SCAMP3.
Traffic (Copenhagen, Denmark) Jan, 2012 | Pubmed ID: 21951651
Duelling functions of the V-ATPase.
The EMBO journal Oct, 2011 | Pubmed ID: 22009224
A novel strategy to identify drugs that interfere with endosomal lipids.
Chimia , 2011 | Pubmed ID: 22289369
Studying lipids involved in the endosomal pathway.
Methods in cell biology , 2012 | Pubmed ID: 22325596
Regulation of the EGF transcriptional response by endocytic sorting.
Science signaling Mar, 2012 | Pubmed ID: 22416276
Single-cell analysis of population context advances RNAi screening at multiple levels.
Molecular systems biology Apr, 2012 | Pubmed ID: 22531119
SNX12 role in endosome membrane transport.
PloS one , 2012 | Pubmed ID: 22719997
An MBoC favorite: Functional interactions between sphingolipids and sterols in biological membranes regulating cell physiology.
Molecular biology of the cell Jul, 2012 | Pubmed ID: 22745339
PNPLA3/adiponutrin functions in lipid droplet formation.
Biology of the cell May, 2013 | Pubmed ID: 23398201
Viral infection controlled by a calcium-dependent lipid-binding module in ALIX.
Developmental cell May, 2013 | Pubmed ID: 23664863
Lipid sorting and multivesicular endosome biogenesis.
Cold Spring Harbor perspectives in biology Oct, 2013 | Pubmed ID: 24086044
ALIX and the multivesicular endosome: ALIX in Wonderland.
Trends in cell biology Jan, 2014 | Pubmed ID: 24287454
Endosome maturation, transport and functions.
Seminars in cell & developmental biology Jul, 2014 | Pubmed ID: 24709024
Discovery of novel membrane binding structures and functions.
Biochemistry and cell biology = Biochimie et biologie cellulaire Dec, 2014 | Pubmed ID: 25394204
Close encounter of the third kind: the ER meets endosomes at fission sites.
Developmental cell Dec, 2014 | Pubmed ID: 25535914
Wnt directs the endosomal flux of LDL-derived cholesterol and lipid droplet homeostasis.
EMBO reports Jun, 2015 | Pubmed ID: 25851648
Secondary structure and (1)H, (13)C, (15)N resonance assignments of the endosomal sorting protein sorting nexin 3.
Biomolecular NMR assignments Oct, 2015 | Pubmed ID: 25893673
Selective Imaging of Late Endosomes with a pH-Sensitive Diazaoxatriangulene Fluorescent Probe.
Journal of the American Chemical Society Feb, 2016 | Pubmed ID: 26799309
Moesin and cortactin control actin-dependent multivesicular endosome biogenesis.
Molecular biology of the cell Nov, 2016 | Pubmed ID: 27605702
The Biochemistry Department of the University of Geneva: Understanding the Molecular Basis and Function of Intracellular Organization.
Chimia Dec, 2009 | Pubmed ID: 28372605
Automated Microscopy and High Content Screens (Phenotypic Screens) in Academia Labs.
Chimia Dec, 2016 | Pubmed ID: 28661361
LLOMe does not release cysteine cathepsins to the cytosol but inactivates them in transiently permeabilized lysosomes.
Journal of cell science Jul, 2017 | Pubmed ID: 28754686
SOBRE A JoVE
Copyright © 2024 MyJoVE Corporation. Todos os direitos reservados