Samuel Lunenfeld Research Institute
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Modulators of the glycine site on NMDA receptors, D-serine and ALX 5407, display similar beneficial effects to clozapine in mouse models of schizophrenia.
Psychopharmacology Apr, 2005 | Pubmed ID: 15759151
In vivo magnetic resonance imaging and semiautomated image analysis extend the brain phenotype for cdf/cdf mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience Apr, 2006 | Pubmed ID: 16641223
Methods to rapidly and accurately screen a large number of ENU mutagenized mice for abnormal motor phenotypes.
Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases Jun, 2006 | Pubmed ID: 16753976
The ampakine CX546 restores the prepulse inhibition and latent inhibition deficits in mGluR5-deficient mice.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology Apr, 2007 | Pubmed ID: 16936708
Absence of the proapoptotic Bax protein extends fertility and alleviates age-related health complications in female mice.
Proceedings of the National Academy of Sciences of the United States of America Mar, 2007 | Pubmed ID: 17360389
Behavioral phenotypes of Disc1 missense mutations in mice.
Neuron May, 2007 | Pubmed ID: 17481393
Mice with reduced NMDA receptor glycine affinity model some of the negative and cognitive symptoms of schizophrenia.
Psychopharmacology Oct, 2008 | Pubmed ID: 18597079
Neto1 is a novel CUB-domain NMDA receptor-interacting protein required for synaptic plasticity and learning.
PLoS biology Feb, 2009 | Pubmed ID: 19243221
Abnormalities in brain structure and behavior in GSK-3alpha mutant mice.
Molecular brain , 2009 | Pubmed ID: 19925672
A new model of the disrupted latent inhibition in C57BL/6J mice after bupropion treatment.
Psychopharmacology Feb, 2010 | Pubmed ID: 20013111
Genetic and pharmacological evidence for schizophrenia-related Disc1 interaction with GSK-3.
Synapse (New York, N.Y.) Mar, 2011 | Pubmed ID: 20687111
Synergistic interactions between PDE4B and GSK-3: DISC1 mutant mice.
Neuropharmacology Mar, 2012 | Pubmed ID: 21376063
Parametric and pharmacological modulations of latent inhibition in mouse inbred strains.
Pharmacology, biochemistry, and behavior Dec, 2011 | Pubmed ID: 21903127
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