Mingyao Liu

Evaluation of the inhibition potential of plumbagin against cytochrome P450 using LC-MS/MS and cocktail approach.

Differential proteomic analysis of bronchoalveolar lavage fluid from lung transplant patients with and without chronic graft dysfunction.

Caffeic acid 3,4-dihydroxy-phenethyl ester suppresses receptor activator of NF-κB ligand–induced osteoclastogenesis and prevents ovariectomy-induced bone loss through inhibition of mitogen-activated protein kinase/activator protein 1 and Ca2+–nuclear factor of activated T-cells cytoplasmic 1 signaling pathways.

Comparative study of regulatory T cells expanded ex vivo from cord blood and adult peripheral blood.

Src tyrosine kinase inhibition prevents pulmonary ischemia-reperfusion-induced acute lung injury.

Synthesis and biological evaluation of heterocyclic ring-fused betulinic acid derivatives as novel inhibitors of osteoclast differentiation and bone resorption.

Pulmonary bacterial communities in surgically resected noncystic fibrosis bronchiectasis lungs are similar to those in cystic fibrosis.

Ex vivo adenoviral vector gene delivery results in decreased vector-associated inflammation pre- and post-lung transplantation in the pig.

Molecular binding of self-assembling peptide EAK16-II with anticancer agent EPT and its implication in cancer cell inhibition.

Usnic acid inhibits breast tumor angiogenesis and growth by suppressing VEGFR2-mediated AKT and ERK1/2 signaling pathways.

Claudin 1 mediates TNFα-induced gene expression and cell migration in human lung carcinoma cells.

KiSS1 and its G-protein-coupled receptor GPR54 in cancer development and metastasis.

Knowledge translation: airway epithelial cell migration and respiratory diseases.

Protective effects of long pentraxin PTX3 on lung injury in a severe acute respiratory syndrome model in mice.

MEK/ERK pathway mediates PKC activation-induced recruitment of PKCζ and MMP-9 to podosomes.

XB130 as an independent prognostic factor in human esophageal squamous cell carcinoma.

Cucurbitacin E inhibits breast tumor metastasis by suppressing cell migration and invasion.

XB130 mediates cancer cell proliferation and survival through multiple signaling events downstream of Akt.

Physiologic assessment of the ex vivo donor lung for transplantation.

Therapeutic effects of inhaling aerosolized surfactant alone or with dexamethasone generated by a novel noninvasive apparatus on acute lung injury in rats.

Norcantharidin facilitates LPS-mediated immune responses by up-regulation of AKT/NF-κB signaling in macrophages.

Microarray meta-analysis identifies acute lung injury biomarkers in donor lungs that predict development of primary graft failure in recipients.

Atypical protein kinase C in cell motility.

MiR-93 enhances angiogenesis and metastasis by targeting LATS2.

Inhibition of breast cancer metastases by a novel inhibitor of TGFβ receptor 1.

A natural small molecule harmine inhibits angiogenesis and suppresses tumour growth through activation of p53 in endothelial cells.

Rejection of tracheal allograft by intrapulmonary lymphoid neogenesis in the absence of secondary lymphoid organs.

Aqp5 is a new transcriptional target of Dot1a and a regulator of Aqp2.

Lgr4 gene deficiency increases susceptibility and severity of dextran sodium sulfate-induced inflammatory bowel disease in mice.

FBW7 regulates endothelial functions by targeting KLF2 for ubiquitination and degradation.

XB130, a new adaptor protein, regulates expression of tumor suppressive microRNAs in cancer cells.

Lgr4-mediated Wnt/β-catenin signaling in peritubular myoid cells is essential for spermatogenesis.

Lgr4/Gpr48 negatively regulates TLR2/4-associated pattern recognition and innate immunity by targeting CD14 expression.

High-efficiency and heritable gene targeting in mouse by transcription activator-like effector nucleases.

PKC activation induces inflammatory response and cell death in human bronchial epithelial cells.

Lgr4 Regulates Mammary Gland Development and Stem Cell Activity through the Pluripotency Transcription Factor Sox2.

Lgr4 in ocular development and glaucoma.

Lgr4 is a key regulator of prostate development and prostate stem cell differentiation.

Heritable gene targeting in the mouse and rat using a CRISPR-Cas system.

GPR116, an adhesion G-protein-coupled receptor, promotes breast cancer metastasis via the Gαq-p63RhoGEF-Rho GTPase pathway.

Zebrafish cancer and metastasis models for in vivo drug discovery.

Efficient gene delivery to pig airway epithelia and submucosal glands using helper-dependent adenoviral vectors.

Inhibitory effects of celastrol on rat liver cytochrome P450 1A2, 2C11, 2D6, 2E1 and 3A2 activity.

Ablation of LGR4 promotes energy expenditure by driving white-to-brown fat switch.

Solid phase microextraction fills the gap in tissue sampling protocols.

Evaluating the pharmacological mechanism of Chinese medicine Si-Wu-Tang through multi-level data integration.

Modified in vivo lung perfusion allows for prolonged perfusion without acute lung injury.

LGR4 acts as a link between the peripheral circadian clock and lipid metabolism in liver.

Biological effects of Tat cell-penetrating peptide: a multifunctional Trojan horse?

α1-Antitrypsin inhibits ischemia reperfusion-induced lung injury by reducing inflammatory response and cell death.

Chimeric anti-IL-17 full-length monoclonal antibody is a novel potential candidate for the treatment of rheumatoid arthritis.

Synthesis and biological evaluation of novel tetrahydro-β-carboline derivatives as antitumor growth and metastasis agents through inhibiting the transforming growth factor-β signaling pathway.

Protein kinase C mediates enterohemorrhagic Escherichia coli O157:H7-induced attaching and effacing lesions.

LGR4/GPR48 inactivation leads to aniridia-genitourinary anomalies-mental retardation syndrome defects.

Metabolomic heterogeneity of pulmonary arterial hypertension.

PKA turnover by the REGγ-proteasome modulates FoxO1 cellular activity and VEGF-induced angiogenesis.

Soluble platelet-endothelial cell adhesion molecule-1, a biomarker of ventilator-induced lung injury.

Gpr48 deficiency induces polycystic kidney lesions and renal fibrosis in mice by activating Wnt signal pathway.

Low invasive in vivo tissue sampling for monitoring biomarkers and drugs during surgery.

Optimization of 2-(3-(arylalkyl amino carbonyl) phenyl)-3-(2-methoxyphenyl)-4-thiazolidinone derivatives as potent antitumor growth and metastasis agents.

Structure of the human P2Y₁₂ receptor in complex with an antithrombotic drug.

History and current status of evidence-based korean medicine.

Lgr4 gene regulates corpus luteum maturation through modulation of the WNT-mediated EGFR-ERK signaling pathway.

Measurement error of surface-mounted fiber Bragg grating temperature sensor.

XB130-A Novel Adaptor Protein: Gene, Function, and Roles in Tumorigenesis.

A note on CYP2J2-mediated terfenadine hydroxylation in human liver microsomes.

Lgr4 protein deficiency induces ataxia-like phenotype in mice and impairs long term depression at cerebellar parallel fiber-Purkinje cell synapses.

Enhancement of the pharmacological efficacy of FGF-21 by genetic modification and PEGylation.

Total synthesis and biological studies of cryptocin and derivatives of equisetin and fusarisetin A.

GPR126 protein regulates developmental and pathological angiogenesis through modulation of VEGFR2 receptor signaling.

Antitumor action of a novel histone deacetylase inhibitor, YF479, in breast cancer.

Toll-like receptor-triggered calcium mobilization protects mice against bacterial infection through extracellular ATP release.

Effects of cucurbitacin e, a tetracyclic triterpene compound from Cucurbitaceae, on the pharmacokinetics and pharmacodynamics of warfarin in rats.

CRISPR/Cas-mediated genome editing in the rat via direct injection of one-cell embryos.

Extracellular UDP and P2Y6 function as a danger signal to protect mice from vesicular stomatitis virus infection through an increase in IFN-β production.

XB130 deficiency affects tracheal epithelial differentiation during airway repair.

Small molecule 1'-acetoxychavicol acetate suppresses breast tumor metastasis by regulating the SHP-1/STAT3/MMPs signaling pathway.

A novel synthetic small molecule YH-306 suppresses colorectal tumour growth and metastasis via FAK pathway.

The antiparasitic drug, potassium antimony tartrate, inhibits tumor angiogenesis and tumor growth in nonsmall-cell lung cancer.

Design and optimization of novel hydroxamate-based histone deacetylase inhibitors of Bis-substituted aromatic amides bearing potent activities against tumor growth and metastasis.

Protein expression profiling predicts graft performance in clinical ex vivo lung perfusion.

De novo synthesize of bile acids in pulmonary arterial hypertension lung.

PubAngioGen: a database and knowledge for angiogenesis and related diseases.

Generation of site-specific mutations in the rat genome via CRISPR/Cas9.

Inhibition of tumor growth by polyarginine-fused mutant cytosine deaminase.

New functions and signaling mechanisms for the class of adhesion G protein-coupled receptors.

Development of a validated LC-MS/MS method for the determination of ailanthone in rat plasma with application to pharmacokinetic study.

Evaluation of enzyme inhibition kinetics in drug-drug interactions.

Long-acting hypoglycemic effects of PEGylated FGF21 and insulin glargine in mice with type 1 diabetes.

Crystal structure of LGR4-Rspo1 complex: insights into the divergent mechanisms of ligand recognition by leucine-rich repeat G-protein-coupled receptors (LGRs).

Oridonin inhibits tumor growth and metastasis through anti-angiogenesis by blocking the Notch signaling.

Claudin 1 mediates tumor necrosis factor alpha-induced cell migration in human gastric cancer cells.

PKCδ-iPLA2-PGE2-PPARγ signaling cascade mediates TNF-α induced Claudin 1 expression in human lung carcinoma cells.

Investigation of cytochrome P450 inhibitory properties of maslinic acid, a bioactive compound from Olea europaea L., and its structure-activity relationship.

Chemokine receptors and their therapeutic opportunities in diseased lung: far beyond leukocyte trafficking.

Targeted deletion of the murine Lgr4 gene decreases lens epithelial cell resistance to oxidative stress and induces age-related cataract formation.

Inhibition of breast cancer progression by a novel histone deacetylase inhibitor, LW479, by down-regulating EGFR expression.

Design and optimization of hybrid of 2,4-diaminopyrimidine and arylthiazole scaffold as anticancer cell proliferation and migration agents.

The role of the endothelin-1 pathway as a biomarker for donor lung assessment in clinical ex vivo lung perfusion.

Lycorine is a novel inhibitor of the growth and metastasis of hormone-refractory prostate cancer.

TAT cell-penetrating peptide modulates inflammatory response and apoptosis in human lung epithelial cells.

The ubiquitination of rag A GTPase by RNF152 negatively regulates mTORC1 activation.

Mechanical Stress and the Induction of Lung Fibrosis via the Midkine Signaling Pathway.

5-Fluoruracil blocked giant cell tumor progression by suppressing osteoclastogenesis through NF-kappaB signals and blocking angiogenesis.

XB130 translocation to microfilamentous structures mediates NNK-induced migration of human bronchial epithelial cells.

Long-Term Administration of Fibroblast Growth Factor 21 Prevents Chemically-Induced Hepatocarcinogenesis in Mice.

Repression of Mammalian Target of Rapamycin Complex 1 Inhibits Intestinal Regeneration in Acute Inflammatory Bowel Disease Models.

Phenotypic diversity within a Pseudomonas aeruginosa population infecting an adult with cystic fibrosis.

Amino Acid-Dependent Attenuation of Toll-like Receptor Signaling by Peptide-Gold Nanoparticle Hybrids.

In vivo selection for spine-derived highly metastatic lung cancer cells is associated with increased migration, inflammation and decreased adhesion.

Effective delivery of a rationally designed intracellular peptide drug with gold nanoparticle-peptide hybrids.

A Novel TGR5 Activator WB403 Promotes GLP-1 Secretion and Preserves Pancreatic β-Cells in Type 2 Diabetic Mice.

Extension of donor lung preservation with hypothermic storage after normothermic ex vivo lung perfusion.

Chromosome Condensation 1-Like (Chc1L) Is a Novel Tumor Suppressor Involved in Development of Histiocyte-Rich Neoplasms.

Altered Profile of Circulating Endothelial-Derived Microparticles in Ventilator-Induced Lung Injury.

Low-dose computed tomography volumetry for subtyping chronic lung allograft dysfunction.

In vitro and in vivo evaluation of cucurbitacin E on rat hepatic CYP2C11 expression and activity using LC-MS/MS.

XB130 promotes bronchioalveolar stem cell and Club cell proliferation in airway epithelial repair and regeneration.

LG308, a Novel Synthetic Compound with Antimicrotubule Activity in Prostate Cancer Cells, Exerts Effective Antitumor Activity.

A Fiber Bragg Grating Sensing Based Triaxial Vibration Sensor.

XB130/Tks5 scaffold protein interaction regulates Src-mediated cell proliferation and survival.

The greedy nature of mutant RAS: a boon for drug discovery targeting cancer metabolism?

Hierarchically micro-patterned nanofibrous scaffolds with a nanosized bio-glass surface for accelerating wound healing.

Using the inherent chemistry of the endothelin-1 peptide to develop a rapid assay for pre-transplant donor lung assessment.

Fibroblast growth factor 21 attenuates hepatic fibrogenesis through TGF-β/smad2/3 and NF-κB signaling pathways.

Design, synthesis and anticancer activities of novel otobain derivatives.

Fractal circuit sensors enable rapid quantification of biomarkers for donor lung assessment for transplantation.

Insulin sensitizes FGF21 in glucose and lipid metabolisms via activating common AKT pathway.

Inhibition of Osteoclastogenesis and Bone Resorption in vitro and in vivo by a prenylflavonoid xanthohumol from hops.

Large genomic fragment deletion and functional gene cassette knock-in via Cas9 protein mediated genome editing in one-cell rodent embryos.

Meet Our Associate Editor.

Annexin V homodimer protects against ischemia reperfusion-induced acute lung injury in lung transplantation.

A hybrid of thiazolidinone with the hydroxamate scaffold for developing novel histone deacetylase inhibitors with antitumor activities.

TLR-Activated Gap Junction Channels Protect Mice against Bacterial Infection through Extracellular UDP Release.

Halofuginone treatment reduces interleukin-17A and ameliorates features of chronic lung allograft dysfunction in a mouse orthotopic lung transplant model.

Circulating Cell Death Biomarkers May Predict Survival in Human Lung Transplantation.

Bortezomib Inhibits Giant Cell Tumor of Bone through Induction of Cell Apoptosis and Inhibition of Osteoclast Recruitment, Giant Cell Formation, and Bone Resorption.

New insights into the androgen biotransformation in prostate cancer: A regulatory network among androgen, androgen receptors and UGTs.

Characterization of novel cytochrome P450 2E1 knockout rat model generated by CRISPR/Cas9.

Modified In Vivo Lung Perfusion for Local Chemotherapy: A Preclinical Study With Doxorubicin.

CRISPR/Cas9-mediated somatic correction of a novel coagulator factor IX gene mutation ameliorates hemophilia in mouse.

Preparation of copper-containing bioactive glass/eggshell membrane nanocomposites for improving angiogenesis, antibacterial activity and wound healing.

XB130 deficiency enhances lipopolysaccharide-induced septic response and acute lung injury.

β-Lapachone Induces NAD(P)H:Quinone Oxidoreductase-1- and Oxidative Stress-Dependent Heat Shock Protein 90 Cleavage and Inhibits Tumor Growth and Angiogenesis.

Measurement of Rhodamine 123 in Three-Dimensional Organoids: A Novel Model for P-Glycoprotein Inhibitor Screening.

LGR4 is a receptor for RANKL and negatively regulates osteoclast differentiation and bone resorption.

Gpr97 is dispensable for metabolic syndrome but is involved in macrophage inflammation in high-fat diet-induced obesity in mice.

Human α1-antitrypsin improves early post-transplant lung function: Pre-clinical studies in a pig lung transplant model.

Importance of left atrial pressure during ex vivo lung perfusion.

Suppression of KRas-mutant cancer through the combined inhibition of KRAS with PLK1 and ROCK.

Generation of obese rat model by transcription activator-like effector nucleases targeting the leptin receptor gene.

Differential Requirement of the Extracellular Domain in Activation of Class B G Protein-coupled Receptors.

Ccndbp1 is a new positive regulator of skeletal myogenesis.

Inhibiting cytoplasmic accumulation of HuR synergizes genotoxic agents in urothelial carcinoma of the bladder.

Linifanib (ABT-869) Potentiates the Efficacy of Chemotherapeutic Agents through the Suppression of Receptor Tyrosine Kinase-Mediated AKT/mTOR Signaling Pathways in Gastric Cancer.

Mesenchymal stem cell treatment is associated with decreased perfusate concentration of interleukin-8 during ex vivo perfusion of donor lungs after 18-hour preservation.

Defeat mutant KRAS with synthetic lethality.

Identification of Genes Involved in Breast Cancer Metastasis by Integrating Protein-Protein Interaction Information with Expression Data.

Efficient liver repopulation of transplanted hepatocyte prevents cirrhosis in a rat model of hereditary tyrosinemia type I.

Formulation of hydrophobic therapeutics with self-assembling peptide and amino acid: A new platform for intravenous drug delivery.

A Novel Model of P-Glycoprotein Inhibitor Screening Using Human Small Intestinal Organoids.

A Self-restricted CRISPR System to Reduce Off-target Effects.

Lgr4 is crucial for skin carcinogenesis by regulating MEK/ERK and Wnt/β-catenin signaling pathways.

Effects of Melanocortin 3 and 4 Receptor Deficiency on Energy Homeostasis in Rats.

3D printing of biomaterials with mussel-inspired nanostructures for tumor therapy and tissue regeneration.

Endosomal pH modulation by peptide-gold nanoparticle hybrids enables potent anti-inflammatory activity in phagocytic immune cells.

A combination therapy for KRAS-mutant lung cancer by targeting synthetic lethal partners of mutant KRAS.

Stimulus-dependent dissociation between XB130 and Tks5 scaffold proteins promotes airway epithelial cell migration.

Design and Fabrication of a Dual-Photoelectrode Fuel Cell towards Cost-Effective Electricity Production from Biomass.

Extracellular ADP facilitates monocyte recruitment in bacterial infection via ERK signaling.

Prevention of Muscle Wasting by CRISPR/Cas9-mediated Disruption of Myostatin In Vivo.

Heritable expansion of the genetic code in mouse and zebrafish.

Proteome-Scale Investigation of Protein Allosteric Regulation Perturbed by Somatic Mutations in 7,000 Cancer Genomes.

Ailanthone targets p23 to overcome MDV3100 resistance in castration-resistant prostate cancer.

A betulinic acid derivative SH479 inhibits collagen-induced arthritis by modulating T cell differentiation and cytokine balance.

Lung Lavage and Surfactant Replacement During Ex Vivo Lung Perfusion for Treatment of Gastric Acid Aspiration-Induced Donor Lung Injury.

Safety and Efficacy of Ex Vivo Donor Lung Adenoviral IL-10 Gene Therapy in a Large Animal Lung Transplant Survival Model.

Exploration and analysis of drug modes of action through feature integration.

Sevoflurane Attenuates Ischemia-Reperfusion Injury in a Rat Lung Transplantation Model.

A novel synthetic small molecule YF-452 inhibits tumor growth through antiangiogenesis by suppressing VEGF receptor 2 signaling.

SH479, a Betulinic Acid Derivative, Ameliorates Experimental Autoimmune Encephalomyelitis by Regulating the T Helper 17/Regulatory T Cell Balance.

Ten years of achievements in biological and medical sciences.

CRISPR knockout rat cytochrome P450 3A1/2 model for advancing drug metabolism and pharmacokinetics research.

Drug Repurposing of Histone Deacetylase Inhibitors That Alleviate Neutrophilic Inflammation in Acute Lung Injury and Idiopathic Pulmonary Fibrosis via Inhibiting Leukotriene A4 Hydrolase and Blocking LTB4 Biosynthesis.

Ailanthone: a new potential drug for castration-resistant prostate cancer.

Comprehensive assessment of Cucurbitacin E related hepatotoxicity and drug-drug interactions involving CYP3A and P-glycoprotein.

Synthesis of heterocyclic ring-fused tricyclic diterpene analogs as novel inhibitors of RANKL-induced osteoclastogenesis and bone resorption.

Elevation of GPRC5A expression in colorectal cancer promotes tumor progression through VNN-1 induced oxidative stress.

Novel hemostatic agents based on gelatin-microbial transglutaminase mix.

Palmitoylated SCP1 is targeted to the plasma membrane and negatively regulates angiogenesis.

Elimination of GPR146-mediated antiviral function through IRF3/HES1-signalling pathway.

CRISPR/Cas9 system: a powerful technology for in vivo and ex vivo gene therapy.

Virus-Triggered ATP Release Limits Viral Replication through Facilitating IFN-β Production in a P2X7-Dependent Manner.

Higher M30 and high mobility group box 1 protein levels in ex vivo lung perfusate are associated with primary graft dysfunction after human lung transplantation.

A conducive bioceramic/polymer composite biomaterial for diabetic wound healing.

Cytochrome P450 3A selectively affects the pharmacokinetic interaction between erlotinib and docetaxel in rats.

Inhibition of histone deacetylases sensitizes EGF receptor-TK inhibitor-resistant non-small-cell lung cancer cells to erlotinib in vitro and in vivo.

Leucine-rich repeat-containing G protein coupled receptor 4 (Lgr4) is necessary for prostate cancer metastasis via epithelial-mesenchymal transition.

Leucine-rich repeat-containing G protein-coupled receptor 4 facilitates vesicular stomatitis virus infection by binding vesicular stomatitis virus glycoprotein.

Donor bronchial wash bile acid and suitability of donor lungs for transplantation.

New Avenues for Nanoparticle-Related Therapies.

Inhibition of regulated necrosis attenuates receptor-interacting protein kinase 1-mediated ischemia-reperfusion injury after lung transplantation.

Pig lung transplant survival model.

Interleukin-8 release during early reperfusion predicts graft function in human lung transplantation.

Soluble transforming growth factor-beta type III receptor gene transfection inhibits fibrous airway obliteration in a rat model of Bronchiolitis obliterans.

A simplified model for en bloc double lung xenotransplantation from hamster to rat.

Transplant immunosuppression enhances efficiency of adenoviral-mediated gene retransfection: inhibition of interferon-gamma and immunoglobin G.

Gain control of N-methyl-D-aspartate receptor activity by receptor-like protein tyrosine phosphatase alpha.

Molecular cloning of actin filament-associated protein: a putative adaptor in stretch-induced Src activation.

Ischemia-reperfusion-induced lung injury.

Accommodation after lung xenografting from hamster to rat.

Impact of human interleukin-10 on vector-induced inflammation and early graft function in rat lung transplantation.

Interleukin 10 gene transfection of donor lungs ameliorates posttransplant cell death by a switch from cellular necrosis to apoptosis.

Increased expression of nitric oxide synthase in human lung transplants after nitric oxide inhalation.

Vascular endothelial growth factor and related molecules in acute lung injury.

Conversion of mechanical force into biochemical signaling.

Caspase inhibition improves ischemia-reperfusion injury after lung transplantation.

Innate immunity and organ transplantation: the potential role of toll-like receptors.

PKA independent and cell type specific activation of the expression of caudal homeobox gene Cdx-2 by cyclic AMP.

Reperfusion-induced gene expression profiles in rat lung transplantation.

Ventilator-induced lung injury: role of protein-protein interaction in mechanosensation.

TNFalpha-induced long pentraxin PTX3 expression in human lung epithelial cells via JNK.

Activation of mitogen-activated protein kinases during human lung transplantation.

Src protein tyrosine kinase family and acute inflammatory responses.

The effect of gender combinations on outcome in human lung transplantation: the International Society of Heart and Lung Transplantation Registry experience.

Lipopolysaccharide accelerates caspase-independent but cathepsin B-dependent death of human lung epithelial cells.

The early responses of VEGF and its receptors during acute lung injury: implication of VEGF in alveolar epithelial cell survival.

Cell-based tissue engineering for lung regeneration.

Toll-like receptor and cytokine gene expression in the early phase of human lung transplantation.

Long pentraxin 3 in pulmonary infection and acute lung injury.

XB130, a novel adaptor protein for signal transduction.

Targeted cell replacement with bone marrow cells for airway epithelial regeneration.

Intestinal ischemia-reperfusion-induced acute lung injury and oncotic cell death in multiple organs.

The Blimp-1 gene regulatory region directs EGFP expression in multiple hematopoietic lineages and testis in mice.

Acute lung injury and cell death: how many ways can cells die?

Anti-human tissue factor antibody ameliorated intestinal ischemia reperfusion-induced acute lung injury in human tissue factor knock-in mice.

Differential gene profiling in acute lung injury identifies injury-specific gene expression.

Phorbol ester-induced podosomes in normal human bronchial epithelial cells.

Technique for prolonged normothermic ex vivo lung perfusion.

The role of intrapulmonary de novo lymphoid tissue in obliterative bronchiolitis after lung transplantation.

Acute lung injury: a yellow card for engineered nanoparticles?

Activated protein C in ischemia-reperfusion injury after experimental lung transplantation.

PTX3 as a potential biomarker of acute lung injury: supporting evidence from animal experimentation.

Functions of type II pneumocyte-derived vascular endothelial growth factor in alveolar structure, acute inflammation, and vascular permeability.

Functional repair of human donor lungs by IL-10 gene therapy.

Activating transcription factor 3 confers protection against ventilator-induced lung injury.

The protein kinase C cascade regulates recruitment of matrix metalloprotease 9 to podosomes and its release and activation.

Long pentraxin PTX3 deficiency worsens LPS-induced acute lung injury.

Adaptor protein XB130 is a Rac-controlled component of lamellipodia that regulates cell motility and invasion.

Transcriptional signatures in donor lungs from donation after cardiac death vs after brain death: a functional pathway analysis.

XB130, a novel adaptor protein, promotes thyroid tumor growth.

Actin filament associated protein mediates c-Src related SRE/AP-1 transcriptional activation.

Increased levels of interleukin-1β and tumor necrosis factor-α in donor lungs rejected for transplantation.

The potential of nanoscale combinations of self-assembling peptides and amino acids of the Src tyrosine kinase inhibitor in acute lung injury therapy.

Stromal activation and formation of lymphoid-like stroma in chronic lung allograft dysfunction.

Local long-term expression of lentivirally delivered IL-10 in the lung attenuates obliteration of intrapulmonary allograft airways.

Regression of allograft airway fibrosis: the role of MMP-dependent tissue remodeling in obliterative bronchiolitis after lung transplantation.

Roles of XB130, a novel adaptor protein, in cancer.

Self-assembling peptide-based nanoparticles enhance cellular delivery of the hydrophobic anticancer drug ellipticine through caveolae-dependent endocytosis.

Programming the cellular uptake of physiologically stable peptide-gold nanoparticle hybrids with single amino acids.

The actin-binding domain of actin filament-associated protein (AFAP) is involved in the regulation of cytoskeletal structure.

α-Anti-trypsin improves function of porcine donor lungs during ex-vivo lung perfusion.

Chronic lung injury and impaired pulmonary function in a mouse model of acid ceramidase deficiency.

Metabolic Profile of Ex Vivo Lung Perfusate Yields Biomarkers for Lung Transplant Outcomes.

Effects of Warm Versus Cold Ischemic Donor Lung Preservation on the Underlying Mechanisms of Injuries During Ischemia and Reperfusion.

Pentraxin 3 deficiency enhances features of chronic rejection in a mouse orthotopic lung transplantation model.

Organ preservation: from the past to the future.

Upregulation of alveolar neutrophil enzymes and long pentraxin-3 in human chronic lung allograft dysfunction subtypes.

A novel combined ex vivo and in vivo lentiviral interleukin-10 gene delivery strategy at the time of transplantation decreases chronic lung allograft rejection in mice.

Ischemia-reperfusion induces death receptor-independent necroptosis via calpain-STAT3 activation in a lung transplant setting.

Spectrum of chronic lung allograft pathology in a mouse minor-mismatched orthotopic lung transplant model.

Identification and Modulation of Microenvironment Is Crucial for Effective Mesenchymal Stromal Cell Therapy in Acute Lung Injury.

Intracellular signal transduction pathways as potential drug targets for ischemia-reperfusion injury in lung transplantation.

Neutrophil extracellular traps in lung perfusion perfusate predict the clinical outcome of lung transplant recipients.

Lentiviral interleukin-10 gene therapy: Safety and questions.

Inactivating hepatitis C virus in donor lungs using light therapies during normothermic ex vivo lung perfusion.

XB130 deficiency enhances carcinogen-induced skin tumorigenesis.

Donor prone positioning protects lungs from injury during warm ischemia.

A B cell-dependent pathway drives chronic lung allograft rejection after ischemia-reperfusion injury in mice.

Mesenchymal stromal cell therapy during ex vivo lung perfusion ameliorates ischemia-reperfusion injury in lung transplantation.

Chemokines and their receptors as biomarkers in esophageal cancer.

Pharmacokinetics, tissue distribution and safety of gold nanoparticle/PKC Delta inhibitor peptide hybrid in rats.

Potential therapeutic targets for lung repair during human lung perfusion.

Increased Arginase Expression and Decreased Nitric Oxide in Pig Donor Lungs after Normothermic Ex Vivo Lung Perfusion.

An extracellular oxygen carrier during prolonged pulmonary preservation improves post-transplant lung function.

Commentary: It's time for exosomes to get the limelight in lung transplant.

Glucagon-like peptide-1 receptor mediates the beneficial effect of liraglutide in an acute lung injury mouse model involving the thioredoxin-interacting protein.

Letter to the editor: Comment on GLP-1-based drugs and COVID-19 treatment.

Cell-free DNA in human ex vivo lung perfusate as a potential biomarker to predict the risk of primary graft dysfunction in lung transplantation.

Strategies to prolong homeostasis of ex vivo perfused lungs.

Ex vivo lung perfusion for donor lung assessment and repair: a review of translational interspecies models.

Veno-venous ECMO as a platform to evaluate lung lavage and surfactant replacement therapy in an animal model of severe ARDS.

Transcriptomic investigation reveals donor-specific gene signatures in human lung transplants.

Safety concerns regarding concomitant use of tocilizumab and glucocorticoids in COVID-19 patients.

Alpha-1 Antitrypsin for COVID-19 Treatment: Dual Role in Antiviral Infection and Anti-Inflammation.

Single-cell analysis reveals transcriptomic remodellings in distinct cell types that contribute to human prostate cancer progression.

Friend or foe? ACE2 inhibitors and GLP-1R agonists in COVID-19 treatment.

α1-Antitrypsin deficiency and the risk of COVID-19: an urgent call to action.

Using nutrient-rich solutions and adding multiple cytoprotective agents as new strategies to develop lung preservation solutions.

Prognostic Impact of CXCR7 and CXCL12 Expression in Patients with Esophageal Adenocarcinoma.

Prediction of donor related lung injury in clinical lung transplantation using a validated ex vivo lung perfusion inflammation score.

ASO Author Reflections: CXCR7 and CXCL12 Expression as Biomarker in Patients with Esophageal Adenocarcinoma.

Tocilizumab in Treatment for Patients With COVID-19.

Use of metabolomics to identify strategies to improve and prolong ex vivo lung perfusion for lung transplants.

Predicting donor lung acceptance for transplant during ex vivo lung perfusion: The EX vivo lung PerfusIon pREdiction (EXPIRE).

Inflammatory responses in lungs from donation after brain death: Mechanisms and potential therapeutic targets.

Surfactant therapy in lung transplantation: A systematic review and meta-analysis.

XB130 Deficiency Causes Congenital Hypothyroidism in Mice due to Disorganized Apical Membrane Structure and Function of Thyrocytes.

delivery of regulatory T-cells for control of alloimmune priming in the donor lung.

Static lung storage at 10°C maintains mitochondrial health and preserves donor organ function.

XB130 Plays an Essential Role in Folliculogenesis Through Mediating Interactions Between Microfilament and Microtubule Systems in Thyrocytes.

Ischemia-Reperfusion Injury in a Simulated Lung Transplant Setting Differentially Regulates Transcriptomic Profiles between Human Lung Endothelial and Epithelial Cells.

Engineered mesenchymal stromal cell therapy during human lung lung perfusion is compromised by acidic lung microenvironment.

Single-Cell Analysis Reveals EP4 as a Target for Restoring T-Cell Infiltration and Sensitizing Prostate Cancer to Immunotherapy.

Ex vivo treatment of cytomegalovirus in human donor lungs using a novel chemokine-based immunotoxin.

Pathogenesis of Multinodular Goiter in Elderly XB130-Deficient Mice: Alteration of Thyroperoxidase Affinity with Iodide and Hydrogen Peroxide.

Proteomics, brain death, and organ transplantation.

Ex vivo enzymatic treatment converts blood type A donor lungs into universal blood type lungs.

Thyroidal Transcriptomic Profiles of Pathoadaptive Responses to Congenital Hypothyroidism in XB130 Knockout Mice.

Near-infrared fluorescence imaging during ex vivo lung perfusion: Noninvasive real-time evaluation of regional lung perfusion and edema.

Altered purine metabolism at reperfusion affects clinical outcome in lung transplantation.

Interferon-stimulated and metallothionein-expressing macrophages are associated with acute and chronic allograft dysfunction after lung transplantation.

Cell death and ischemia-reperfusion injury in lung transplantation.

Successful 3-day lung preservation using a cyclic normothermic ex vivo lung perfusion strategy.

A biomarker assay to risk-stratify patients with symptoms of respiratory tract infection.

Evaluation of 10°C as the optimal storage temperature for aspiration-injured donor lungs in a large animal transplant model.

Determining the impact of ex-vivo lung perfusion on hospital costs for lung transplantation: A retrospective cohort study.

L-alanyl-L-glutamine modified perfusate improves human lung cell functions and extend porcine ex vivo lung perfusion.

Triaging donor lungs based on a microaspiration signature that predicts adverse recipient outcome.

Defining and targeting tumor-associated macrophages in malignant mesothelioma.

Alpha-1-antitrypsin safely promotes rapid recovery of pigs after lung transplantation.

Evaluating the Impact of Ex Vivo Lung Perfusion on Organ Transplantation: A Retrospective Cohort Study.

Immunomodulation of the donor lung with CRISPR-mediated activation of IL-10 expression.

A Novel Tissue Preservation and Transport Solution as a Substitute for Formalin.

A cell-free tissue-engineered tracheal substitute with sequential cytokine release maintained airway opening in a rabbit tracheal full circumferential defect model.

Mesenchymal Stromal Cell Therapy in Lung Transplantation.

Time to extubation for lung transplant recipients represents a pragmatic end-point to guide the development of prognostic tests.

Identification of regional variation in gene expression and inflammatory proteins in donor lung tissue and ex vivo lung perfusate.

A machine-learning approach to human ex vivo lung perfusion predicts transplantation outcomes and promotes organ utilization.

De Novo Design and Development of a Nutrient-Rich Perfusate for Ex Vivo Lung Perfusion with Cell Culture Models.

Necroptosis in Organ Transplantation: Mechanisms and Potential Therapeutic Targets.

Applications and safety of gold nanoparticles as therapeutic devices in clinical trials.

Acellular ex vivo lung perfusate silences pro-inflammatory signaling in human lung endothelial and epithelial cells.

Donor IL-17 receptor A regulates LPS-potentiated acute and chronic murine lung allograft rejection.