Coleen Murphy
Department of Molecular Biology,
Lewis-Sigler Institute for Integrative Genomics,
Department of Molecular Biology, Lewis-Sigler Institute for Integrative Genomics
Princeton University
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Regulation of aging and age-related disease by DAF-16 and heat-shock factor.
Science (New York, N.Y.) May, 2003 | Pubmed ID: 12750521
Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans.
Nature Jul, 2003 | Pubmed ID: 12845331
Comparing genomic expression patterns across species identifies shared transcriptional profile in aging.
Nature genetics Feb, 2004 | Pubmed ID: 14730301
Enrichment of regulatory motifs upstream of predicted DAF-16 targets.
Nature genetics Apr, 2006 | Pubmed ID: 16570056
The search for DAF-16/FOXO transcriptional targets: approaches and discoveries.
Experimental gerontology Oct, 2006 | Pubmed ID: 16934425
The C. elegans TGF-beta Dauer pathway regulates longevity via insulin signaling.
Current biology : CB Oct, 2007 | Pubmed ID: 17900898
Tissue entrainment by feedback regulation of insulin gene expression in the endoderm of Caenorhabditis elegans.
Proceedings of the National Academy of Sciences of the United States of America Nov, 2007 | Pubmed ID: 18025456
Global prediction of tissue-specific gene expression and context-dependent gene networks in Caenorhabditis elegans.
PLoS computational biology Jun, 2009 | Pubmed ID: 19543383
Condition-adapted stress and longevity gene regulation by Caenorhabditis elegans SKN-1/Nrf.
Aging cell Sep, 2009 | Pubmed ID: 19575768
Glucose shortens the life span of C. elegans by downregulating DAF-16/FOXO activity and aquaporin gene expression.
Cell metabolism Nov, 2009 | Pubmed ID: 19883616
TGF-beta Sma/Mab signaling mutations uncouple reproductive aging from somatic aging.
PLoS genetics Dec, 2009 | Pubmed ID: 20041217
Integration of diverse inputs in the regulation of Caenorhabditis elegans DAF-16/FOXO.
Developmental dynamics : an official publication of the American Association of Anatomists May, 2010 | Pubmed ID: 20140911
The role of insulin/IGF-like signaling in C. elegans longevity and aging.
Disease models & mechanisms Jul-Aug, 2010 | Pubmed ID: 20354111
Insulin signaling and dietary restriction differentially influence the decline of learning and memory with age.
PLoS biology May, 2010 | Pubmed ID: 20502519
TGF-β and insulin signaling regulate reproductive aging via oocyte and germline quality maintenance.
Cell Oct, 2010 | Pubmed ID: 20946987
Caenorhabditis elegans reproductive aging: Regulation and underlying mechanisms.
Genesis (New York, N.Y. : 2000) Feb, 2011 | Pubmed ID: 21105070
Aging: miRacles of longevity?
Current biology : CB Dec, 2010 | Pubmed ID: 21172627
EGF signalling activates the ubiquitin proteasome system to modulate C. elegans lifespan.
The EMBO journal Aug, 2011 | Pubmed ID: 21673654
The evolutionarily conserved longevity determinants HCF-1 and SIR-2.1/SIRT1 collaborate to regulate DAF-16/FOXO.
PLoS genetics Sep, 2011 | Pubmed ID: 21909281
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