Robert O. Messing

Protein kinase C epsilon regulates gamma-aminobutyrate type A receptor sensitivity to ethanol and benzodiazepines through phosphorylation of gamma2 subunits.

Cardioprotection mediated by sphingosine-1-phosphate and ganglioside GM-1 in wild-type and PKC epsilon knockout mouse hearts.

Decreased anxiety-like behavior, reduced stress hormones, and neurosteroid supersensitivity in mice lacking protein kinase Cepsilon.

Conditional rescue of protein kinase C epsilon regulates ethanol preference and hypnotic sensitivity in adult mice.

Protein kinase C-epsilon-null mice have decreased hypoxic pulmonary vasoconstriction.

Genetic approaches to studying protein kinase C: an introduction.

Animal models in the study of protein kinase C isozymes.

Preservation of base-line hemodynamic function and loss of inducible cardioprotection in adult mice lacking protein kinase C epsilon.

The mouse RACK1 gene is regulated by nuclear factor-kappa B and contributes to cell survival.

Protein kinase C isozymes and addiction.

Neutrophil protein kinase Cdelta as a mediator of stroke-reperfusion injury.

The type 1 equilibrative nucleoside transporter regulates ethanol intoxication and preference.

Deletion of N-type calcium channels alters ethanol reward and reduces ethanol consumption in mice.

The mGluR5 antagonist 6-methyl-2-(phenylethynyl)pyridine decreases ethanol consumption via a protein kinase C epsilon-dependent mechanism.

Specific modulation of Na+ channels in hippocampal neurons by protein kinase C epsilon.

Chronic ethanol exposure induces an N-type calcium channel splice variant with altered channel kinetics.

Protein kinase C isozymes in stroke.

Role of the protein kinase C-epsilon-Raf-1-MEK-1/2-p44/42 MAPK signaling cascade in the activation of signal transducers and activators of transcription 1 and 3 and induction of cyclooxygenase-2 after ischemic preconditioning.

Acute functional tolerance to ethanol mediated by protein kinase Cepsilon.

PKCepsilon increases endothelin converting enzyme activity and reduces amyloid plaque pathology in transgenic mice.

Ethanol withdrawal induces hyperalgesia mediated by PKCepsilon.

Early editorial manuscript screening versus obligate peer review: a randomized trial.

A semisynthetic epitope for kinase substrates.

nPKCepsilon, a P2Y2-R downstream effector in regulated mucin secretion from airway goblet cells.

Alcohol-induced stress in painful alcoholic neuropathy.

Hypertensive encephalopathy and the blood-brain barrier: is deltaPKC a gatekeeper?

The identification and characterization of novel PKCepsilon phosphorylation sites provide evidence for functional cross-talk within the PKC superfamily.

Neurotoxic catecholamine metabolite in nociceptors contributes to painful peripheral neuropathy.

A blocker of N- and T-type voltage-gated calcium channels attenuates ethanol-induced intoxication, place preference, self-administration, and reinstatement.

Protein kinases and addiction.

Protein kinase Cdelta regulates ethanol intoxication and enhancement of GABA-stimulated tonic current.

PKCepsilon regulates behavioral sensitivity, binding and tolerance to the CB1 receptor agonist WIN55,212-2.

The role of the equilibrative nucleoside transporter 1 (ENT1) in transport and metabolism of ribavirin by human and wild-type or Ent1-/- mouse erythrocytes.

The N-type calcium channel is a novel target for treating alcohol use disorders.

Neurobiological mechanisms contributing to alcohol-stress-anxiety interactions.

Status report: the Annals in 2010.

The substrates and binding partners of protein kinase Cepsilon.

PKC-delta promotes renal tubular cell apoptosis associated with proteinuria.

GABAA receptor trafficking is regulated by protein kinase C(epsilon) and the N-ethylmaleimide-sensitive factor.

Should the reorganization of addiction-related research across all the National Institutes of Health be structural?--The devil is truly in the details.

How Should Addiction-Related Research at the National Institutes of Health be Reorganized?

Inhibition of PKCδ reduces cisplatin-induced nephrotoxicity without blocking chemotherapeutic efficacy in mouse models of cancer.

Signaling Pathways Mediating Alcohol Effects.

Protein kinase C epsilon modulates nicotine consumption and dopamine reward signals in the nucleus accumbens.

Fighting decision fatigue.